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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)262
The number (and %) of the onco-proteins47 (17.94 %)
The number (and %) of the tumor suppressors25 (9.54 %)
Total number of binary PPIs (saturation %)934 (2.73 %)
The number (and %) of affected PPIs260 (27.84 %)
The number of possible different fusions27
PPI diameter5
PPI radius3
The average degree of PPI6.641
Assortativity coefficient-0.3929
The network average Clustering coefficient0.347
The number (and %) of a zero Clustering coefficients93 (35.50 %)
The number (and %) of a zero Betweenness Centrality109 (41.60 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ADD1,MEOX2 All fusions
Proteins found in more fusions TRAF6 (see 1 fusions); MAGED1 (see 1 fusions); VCP (see 4 fusions); HMG20A (see 2 fusions); ZDHHC17 (see 2 fusions); C19orf66 (see 2 fusions); TPM3 (see 3 fusions); RUNX1T1 (see 1 fusions); PARK2 (see 1 fusions); NTRK1/TPM3 (see 2 fusions); UBE3A (see 1 fusions); HNRNPD (see 1 fusions); MVP (see 2 fusions); TPM2 (see 1 fusions); AHCYL1 (see 2 fusions); MAPRE1 (see 1 fusions); CEP57L1 (see 1 fusions); KAT5 (see 3 fusions); TXLNA (see 3 fusions); SMARCC1 (see 2 fusions); IKBKB (see 2 fusions); RPA1 (see 1 fusions); PACSIN2 (see 1 fusions); SET (see 1 fusions); CTNNBL1 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ADD1parental protein480.1184573.975Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
2 MEOX2parental protein2120.01655029.779Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
3 ADAMTS12interactor100ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1
Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide
PLAC (PF08686, IPR010909, SM00022): PLAC (protease and lacunin) domain
Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
4 ADD3oncoprotein80.321110.644Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain
5 AGPAT1interactor100Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase
DUF2706 (PF10913, IPR024444): Protein of unknown function (DUF2706)
6 AHCYL1suppressor90.179699.436AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515)
Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3)
7 AHSA2interactor100AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
ENOD40 (PF08247, IPR013186): ENOD40 protein
8 ANKRD29interactor21.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
9 ANP32Boncoprotein60.333242.646FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
SDA1 (PF05285, IPR007949): SDA1
LRR_9 (PF14580): Leucine-rich repeat
10 ARHGEF7interactor40.167176.470Borrelia_lipo_1 (PF05714, IPR008421): Borrelia burgdorferi virulent strain associated lipoprotein
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7
RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7
11 ARNT2interactor40.5004.369HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
12 ATG5interactor40462.089APG5 (PF04106, IPR007239): Autophagy protein Apg5
13 ATL2interactor31.0000GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain
GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
14 ATXN1Linteractor3069.314AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
15 BCL2L15interactor100Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
16 C19orf66protein found in more fusions120.8730.733UPF0515 (PF15135, IPR026795): Uncharacterised protein UPF0515
17 C1orf109interactor40.33373.172CK2S (PF15011, IPR029159): Casein Kinase 2 substrate
18 CALM1interactor130.154348.841EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
19 CAPZA2interactor140.374130.423F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
20 CARD9interactor110.53313.118CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
21 CASP14interactor21.0000Peptidase_C14 (PF00656, IPR011600): Caspase domain
22 CCDC103interactor100RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3
Dynein_attach_N (PF15867, IPR031733): Dynein attachment factor N-terminus
23 CCNCsuppressor21.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
24 CDH9interactor100Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Rifin_STEVOR (PF02009, IPR002858): Rifin/stevor family
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
25 CDKN2AIPinteractor60.53313.950XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD
26 CEP57L1protein found in more fusions60.4006.878Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
XhlA (PF10779, IPR019715): Haemolysin XhlA
YqzE (PF14038, IPR025622): YqzE-like protein
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
27 CHIC2oncoprotein80.8930.330Erf4 (PF10256, IPR019383): Golgin subfamily A member 7/ERF4 family
28 CHRDinteractor110.72721.601CHRD (PF07452, IPR010895, SM00754): CHRD domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
29 CIAPIN1interactor200CIAPIN1 (PF05093, IPR007785): Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis
Methyltransf_11 (PF08241, IPR013216): Methyltransferase domain
Methyltransf_31 (PF13847, IPR025714): Methyltransferase domain
30 CIB3interactor21.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
31 CNTNAP2suppressor100COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain
EGF (PF00008, IPR000742, SM00181): EGF-like domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
SCRL (PF06876, IPR010682): Plant self-incompatibility response (SCRL) protein
Syndecan (PF01034, IPR027789): Syndecan domain
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
32 CPNE6interactor30.333339.159C2 (PF00168, IPR000008, SM00239): C2 domain
Copine (PF07002, IPR010734): Copine
33 CPSF4interactor2054.328zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-CCCH_3 (PF15663): Zinc-finger containing family
34 CRCT1interactor60.9330.125NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
35 CSDC2interactor100CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
36 CSF2suppressor200GM_CSF (PF01109, IPR000773, SM00040): Granulocyte-macrophage colony-stimulating factor
37 CSNK2Binteractor120.182297.548CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
38 CTNNBL1protein found in more fusions40.33371.650Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DASH_Dad4 (PF08650, IPR013959): DASH complex subunit Dad4
CTNNBL (PF08216, IPR013180, SM01156): Catenin-beta-like, Arm-motif containing nuclear
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
39 CXXC1interactor100ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLATZ (PF04640, IPR006734): PLATZ transcription factor
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347)
zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain
40 DGCR6interactor80.250471.089DGCR6 (PF07324, IPR010849): DiGeorge syndrome critical region 6 (DGCR6) protein
41 DGCR8interactor100dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
WW (PF00397, IPR001202, SM00456): WW domain
42 DOCK8interactor31.0000DHR-2 (PF06920, IPR010703): Dock homology region 2
DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
DOCK_N (PF16172, IPR032376): DOCK N-terminus
43 DPPA4interactor4077.220Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
DCR (PF14047, IPR025891): Dppa2/4 conserved region
Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates
44 DSToncoprotein80.321275.780CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Phasin (PF05597, IPR008769): Poly(hydroxyalcanoate) granule associated protein (phasin)
Spectrin (PF00435, IPR002017): Spectrin repeat
Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal
XhlA (PF10779, IPR019715): Haemolysin XhlA
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
NYD-SP28 (PF14772): Sperm tail
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
45 DYNC1I2interactor60.60045.425Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
Dynein_IC2 (PF11540, IPR025956): Cytoplasmic dynein 1 intermediate chain 2
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4329 (PF14220, IPR025479): Domain of unknown function (DUF4329)
46 DYNLL2interactor31.0000Dynein_light (PF01221, IPR001372): Dynein light chain type 1
47 DYNLT1interactor50.5005.324Tctex-1 (PF03645, IPR005334): Tctex-1 family
48 EDF1interactor20188.144MBF1 (PF08523, IPR013729): Multiprotein bridging factor 1
HTH_3 (PF01381, IPR001387, SM00530): Helix-turn-helix
49 EFEMP2interactor50.4006.167EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Adipogenin (PF15202, IPR027938): Adipogenin
50 EFNA3interactor21.0000Ephrin (PF00812, IPR001799): Ephrin
Epiglycanin_C (PF14654, IPR028199): Mucin, catalytic, TM and cytoplasmic tail region
51 EIF1ADinteractor21.0000eIF-1a (PF01176, IPR006196): Translation initiation factor 1A / IF-1
52 EIF5Ainteractor30122.942EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
53 EPM2AIP1interactor3069.314Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
54 ESR2suppressor70.267144.521zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
55 ESRRGoncoprotein31.0000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
56 FAM13Cinteractor31.0000Mnd1 (PF03962, IPR005647): Mnd1 family
SlyX (PF04102, IPR007236): SlyX
MRI (PF15325, IPR028278): Modulator of retrovirus infection
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
57 FAM3Ainteractor21.0000ILEI (PF15711): Interleukin-like EMT inducer
58 FAM74A4interactor90.5837.395NA
59 FAM78Ainteractor21.0000ArgJ (PF01960, IPR002813): ArgJ family
60 FBF1interactor60.33381.815DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
YlqD (PF11068, IPR021297): YlqD protein
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
61 FOXR1interactor30.333111.692Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
62 FUCA2interactor100Alpha_L_fucos (PF01120, IPR000933, SM00812): Alpha-L-fucosidase
Fucosidase_C (PF16757, IPR031919): Alpha-L-fucosidase C-terminal domain
63 FUT11interactor100Glyco_transf_10 (PF00852, IPR001503): Glycosyltransferase family 10 (fucosyltransferase) C-term
Glyco_tran_10_N (PF17039, IPR031481): Fucosyltransferase, N-terminal
64 GABRB3interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
65 GAGE1interactor100GAGE (PF05831, IPR008625): GAGE protein
66 GEMIN7interactor2024.179Gemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7)
SUZ-C (PF12901, IPR024642): SUZ-C motif
67 GLO1interactor100Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
68 GMCL1P1interactor21.0000NA
69 GMPR2interactor100IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
70 GNG11interactor100G-gamma (PF00631, IPR015898, SM00224): GGL domain
71 GOLGA8DPinteractor100NA
72 GOLGA8EPinteractor50.6000.956NA
73 GOLGA8Finteractor21.0000T3SS_needle_E (PF08988, IPR012671): Type III secretion system, cytoplasmic E component of needle
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FlxA (PF14282, IPR025577): FlxA-like protein
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
74 GPATCH2Linteractor50.50099.305NA
75 GPSM3interactor20435.320GoLoco (PF02188, IPR003109, SM00390): GoLoco motif
PRIMA1 (PF16101): Proline-rich membrane anchor 1
76 HAT1interactor30.33372.224Hat1_N (PF10394, IPR019467): Histone acetyl transferase HAT1 N-terminus
Acetyltransf_7 (PF13508, IPR000182): Acetyltransferase (GNAT) domain
Acetyltransf_10 (PF13673, IPR000182): Acetyltransferase (GNAT) domain
77 HDAC1suppressor190.176516.268FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
78 HDHD2interactor100Hydrolase_like (PF13242): HAD-hyrolase-like
Hydrolase_6 (PF13344, IPR006357): Haloacid dehalogenase-like hydrolase
79 HEXIM2interactor60.40081.981bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
80 HGFoncoprotein200Kringle (PF00051, IPR000001): Kringle domain
PAN_1 (PF00024, IPR003014): PAN domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
81 HLA-Aoncoprotein60.133463.196DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
82 HMG20Aprotein found in more fusions50.16770.720DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
MlaC (PF05494, IPR008869): MlaC protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
83 HNRNPDoncoprotein80.238383.183CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
84 HP1BP3interactor50.100432.429RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SDA1 (PF05285, IPR007949): SDA1
YL1 (PF05764, IPR008895): YL1 nuclear protein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
85 HSPA2interactor40.333172.836HSP70 (PF00012, IPR013126): Hsp70 protein
86 HSPG2oncoprotein100C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
EGF (PF00008, IPR000742, SM00181): EGF-like domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Laminin_B (PF00052, IPR000034): Laminin B (Domain IV)
Laminin_G_1 (PF00054, IPR001791): Laminin G domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
hEGF (PF12661, IPR013032): Human growth factor-like EGF
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
87 HSPH1oncoprotein40.33364.743HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
88 HTR1Einteractor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
89 IFI16suppressor80.143164.977HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
90 IGF2BP3interactor2069.314RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
91 IGFN1interactor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Tetradecapep (PF08187, IPR012619): Myoactive tetradecapeptides family
KRTAP (PF11759, IPR021743): Keratin-associated matrix
CXCR4_N (PF12109, IPR022726): CXCR4 Chemokine receptor N terminal
92 IKBKBprotein found in more fusions50.33386.215FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
93 INF2interactor60.6009.998Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
94 INPP1interactor100Inositol_P (PF00459, IPR000760): Inositol monophosphatase family
95 IP6K2interactor100IPK (PF03770, IPR005522): Inositol polyphosphate kinase
96 IQGAP1interactor180.431143.619CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
97 ITM2Ainteractor100BRICHOS (PF04089, IPR007084, SM01039): BRICHOS domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
98 KAT5suppressor130.152903.670MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
99 KDM5Binteractor2039.097ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
JmjN (PF02375, IPR003349, SM00545): jmjN domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLU-1 (PF08429, IPR013637): PLU-1-like protein
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Rubredoxin (PF00301, IPR024935): Rubredoxin
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
Lipoprotein_20 (PF13942, IPR025262): YfhG lipoprotein
100 KIZoncoprotein100IncA (PF04156, IPR007285): IncA protein
101 KLC4interactor40.333100.105Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
LUD_dom (PF02589): LUD domain
102 KLHL38interactor70.6677.283BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_6 (PF13964): Kelch motif
103 KRT80interactor100Filament (PF00038, IPR001664): Intermediate filament protein
Rhomboid_SP (PF12595, IPR022241): Rhomboid serine protease
Keratin_2_head (PF16208, IPR032444): Keratin type II head
104 KRT86interactor100Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
105 KRTAP10-1interactor230.39456.789Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
106 KRTAP10-11interactor50.9000.118Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
107 KRTAP10-3interactor420.263545.939Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
108 KRTAP10-5interactor280.299147.742Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
109 KRTAP10-8interactor360.279238.349Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
PMG (PF05287, IPR007951): PMG protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
110 KRTAP10-9interactor390.249456.217Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
111 KRTAP12-1interactor70.7620.490Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
112 KRTAP12-4interactor100Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
113 KRTAP4-11interactor61.0000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
114 KRTAP4-12interactor210.55343.225Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
115 KRTAP4-2interactor240.43868.842Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
116 KRTAP4-7interactor51.0000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
117 KRTAP5-6interactor110.8730.733NA
118 KRTAP5-9interactor300.400132.928Ery_res_leader2 (PF08057, IPR012559): Erythromycin resistance leader peptide
119 KRTAP9-2interactor230.515216.287Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
120 KTN1oncoprotein30.33399.665ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PTPS (PF01242, IPR007115): 6-pyruvoyl tetrahydropterin synthase
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Fimbrial_PilY2 (PF14481, IPR029497): Type 4 fimbrial biogenesis protein PilY2
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
121 LAMTOR5interactor30.33381.632LAMTOR5 (PF16672, IPR024135): Ragulator complex protein LAMTOR5
122 LCE1Binteractor120.8481.427LCE (PF14672, IPR028205): Late cornified envelope
123 LCE2Ainteractor80.9290.174LCE (PF14672, IPR028205): Late cornified envelope
124 LCE4Ainteractor90.8890.417LCE (PF14672, IPR028205): Late cornified envelope
125 LOC153684interactor21.0000NA
126 LRWD1interactor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
127 LSM2interactor21.0000LSM (PF01423, IPR001163): LSM domain
128 MAGED1protein found in more fusions40.33376.167MAGE (PF01454, IPR002190): MAGE family
129 MAP1LC3Binteractor30.33321.382Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
130 MAPKBP1interactor90.9440.205eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
131 MAPRE1oncoprotein130.318200.420CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
132 MEOX1interactor80.25034.964Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
133 MKRN3oncoprotein50.5005.401zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
Torus (PF16131, IPR032297): Torus domain
zf-3CxxC_2 (PF17180): Zinc-binding domain
134 MLLT6oncoprotein31.0000DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
PHD_2 (PF13831): PHD-finger
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
SOBP (PF15279, IPR026092): Sine oculis-binding protein
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
135 MMP3interactor100Peptidase_M10 (PF00413, IPR001818): Matrixin
PG_binding_1 (PF01471, IPR002477): Putative peptidoglycan binding domain
Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
136 MMS19interactor70.238157.616DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
137 MORN3interactor21.0000MORN (PF02493, IPR003409, SM00698): MORN repeat
TFIIIC_sub6 (PF10419, IPR019481): TFIIIC subunit
138 MRFAP1L1interactor40.33358.777MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1
139 MSI2oncoprotein60.333338.703NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
140 MT-CO1interactor100DUF3485 (PF11984, IPR014263): Protein of unknown function (DUF3485)
141 MT1DPsuppressor30.6670.087NA
142 MTMR10interactor100Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
TAP42 (PF04177, IPR007304): TAP42-like family
3-PAP (PF12578, IPR022587): Myotubularin-associated protein
143 MUM1interactor100PWWP (PF00855, IPR000313, SM00293): PWWP domain
144 MVPoncoprotein40.6671.000Vault (PF01505, IPR002499): Major Vault Protein repeat
DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543)
MVP_shoulder (PF11978, IPR021870): Shoulder domain
145 MYBPC1interactor2065.327fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
146 MYO1Cinteractor140.527115.579IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
147 NAA10oncoprotein40.500120.157Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
148 NALCNinteractor100Ion_trans (PF00520, IPR005821): Ion transport protein
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
SPX (PF03105, IPR004331): SPX domain
149 NCALDinteractor100EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
150 NCK2interactor50.5003.725SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
151 ND1interactor100NA
152 NESinteractor30.6673.965Anthrax-tox_M (PF09156, IPR015239): Anthrax toxin lethal factor, middle domain
Filament (PF00038, IPR001664): Intermediate filament protein
HSCB_C (PF07743, IPR009073): HSCB C-terminal oligomerisation domain
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Prominin (PF05478, IPR008795): Prominin
153 NLGN3interactor100COesterase (PF00135, IPR002018): Carboxylesterase family
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
154 NTF3interactor2069.314NGF (PF00243, IPR002072, SM00140): Nerve growth factor family
155 NTRK1oncoprotein480.0683859.673I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
156 NUP54interactor60.40069.853Regulator_TrmB (PF11495, IPR021586): Archaeal transcriptional regulator TrmB
KRTAP (PF11759, IPR021743): Keratin-associated matrix
Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
157 OIT3interactor100Zona_pellucida (PF00100, IPR001507, SM00241): Zona pellucida-like domain
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
158 OSGIN1suppressor100Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase
159 P4HA3interactor100HrpB1_HrpK (PF09613, IPR013394): Bacterial type III secretion protein (HrpB1_HrpK)
P4Ha_N (PF08336, IPR013547): Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
SPO22 (PF08631, IPR013940): Meiosis protein SPO22/ZIP4 like
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
160 PACSIN2oncoprotein200DegS (PF05384, IPR008595): Sensor protein DegS
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
SH3BP5 (PF05276, IPR007940): SH3 domain-binding protein 5 (SH3BP5)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NPF (PF16601): Rabosyn-5 repeating NPF sequence-motif
161 PAGE2interactor100GAGE (PF05831, IPR008625): GAGE protein
162 PARK2suppressor130.167707.517IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
163 PARVGinteractor100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
164 PAX1interactor21.0000PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
165 PAX3oncoprotein30.33348.691PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Pax7 (PF12360, IPR022106): Paired box protein 7
166 PCDH9suppressor100Cadherin_2 (PF08266, IPR013164): Cadherin-like
Protocadherin (PF08374, IPR013585): Protocadherin
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
167 PCSK5interactor60.8670.571P_proprotein (PF01483, IPR002884): Proprotein convertase P-domain
Peptidase_S8 (PF00082, IPR000209): Subtilase family
VSP (PF03302, IPR005127): Giardia variant-specific surface protein
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
Furin-like_2 (PF15913, IPR006212): Furin-like repeat, cysteine-rich
S8_pro-domain (PF16470, IPR032815): Peptidase S8 pro-domain
168 PGBD1interactor200SCAN (PF02023, IPR003309, SM00431): SCAN domain
DDE_Tnp_1_7 (PF13843, IPR029526): Transposase IS4
169 PIN1suppressor110.309134.890Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
170 PKIGoncoprotein2082.556PKI (PF02827, IPR004171): cAMP-dependent protein kinase inhibitor
171 POM121Cinteractor20134.305T2SSC (PF11356): Type II secretion system protein C
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
POM121 (PF15229): POM121 family
172 PRKAB2interactor150.473725.544AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain
AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase
173 PRR19interactor100Pro-rich_19 (PF15455, IPR029355): Proline-rich 19
174 PSMB10interactor100Proteasome (PF00227, IPR001353): Proteasome subunit
Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal
175 PSMC1interactor70.571144.607AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
DivIC (PF04977, IPR007060): Septum formation initiator
DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815)
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
176 PSMD14interactor50.70072.118JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
177 PTGER3interactor80.53610.7957tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
FtsX (PF02687, IPR003838): FtsX-like permease family
178 RARBsuppressor21.0000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
179 RCHY1suppressor50.33377.757C1_2 (PF03107, IPR004146): C1 domain
zf-CHY (PF05495, IPR008913): CHY zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zinc_ribbon_6 (PF14599): Zinc-ribbon
180 RECKsuppressor100DB (PF01682, IPR002602): DB module
DNA_pol_E_B (PF04042, IPR007185): DNA polymerase alpha/epsilon subunit B
Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
Kazal_2 (PF07648, IPR002350, SM00280): Kazal-type serine protease inhibitor domain
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
181 RELAoncoprotein100.278377.635DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
182 RHOJinteractor21.0000Ras (PF00071, IPR001806, SM00173): Ras family
183 RMND5Ainteractor21.0000CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
SnoaL_4 (PF13577, IPR009959): SnoaL-like domain
184 RND2interactor100Ras (PF00071, IPR001806, SM00173): Ras family
185 RNF10interactor2054.328GCS2 (PF04107, IPR006336): Glutamate-cysteine ligase family 2(GCS2)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
186 RPA1suppressor200.281440.027Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
187 RPA2oncoprotein130.449125.647RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
188 RPA3interactor150.385213.581Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
189 RPL15interactor70.286344.244Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
190 RUNX1T1oncoprotein70.267145.386NHR2 (PF08788, IPR014896): NHR2 domain like
TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF
zf-MYND (PF01753, IPR002893): MYND finger
DUF3731 (PF12531, IPR021030): DNA-K related protein
191 SAMM50interactor100Bac_surface_Ag (PF01103, IPR000184): Surface antigen
POTRA (PF07244, IPR010827): Surface antigen variable number repeat
192 SCNM1interactor90.333314.645zf-SCNM1 (PF15803, IPR031622): Zinc-finger of sodium channel modifier 1
SCNM1_acidic (PF15805, IPR031625): Acidic C-terminal region of sodium channel modifier 1 SCNM1
193 SELENOPinteractor100SelP_C (PF04593, IPR007672): Selenoprotein P, C terminal region
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
194 SEToncoprotein70.200379.377NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
195 SIN3Aoncoprotein110.382235.850Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
196 SIRPB1interactor100CD34_antigen (PF06365, IPR013836): CD34/Podocalyxin family
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
197 SLC48A1interactor100HRG (PF16954, IPR026218): Haem-transporter, endosomal/lysosomal, haem-responsive gene
198 SMAD3oncoprotein120.255765.115MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
199 SMARCA2suppressor70.71433.861DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
200 SMARCA4suppressor90.61194.927DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
201 SMARCC1suppressor100.61166.835SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
202 SMARCE1interactor130.205857.366DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
203 SPATA1interactor100NA
204 SPP1oncoprotein40.33372.723Osteopontin (PF00865, IPR002038, SM00017): Osteopontin
205 SPRY1interactor100.7115.886PAP1 (PF08601, IPR013910): Transcription factor PAP1
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
206 SPRY2suppressor310.324447.852KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
207 SPTAN1oncoprotein140.495352.320EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
208 SPTBinteractor21.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Com_YlbF (PF06133, IPR010368): Control of competence regulator ComK, YlbF/YmcA
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
209 SPTBN1suppressor130.526111.506CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
210 SSX3interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
211 STK16interactor110.444157.714Pkinase (PF00069, IPR000719): Protein kinase domain
212 STX11interactor140.192100.623KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
213 STX16interactor2055.880Erp_C (PF06780, IPR009618): Erp protein C-terminus
Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
214 SVILinteractor120.379234.350Gelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
215 SYT17interactor21.0000C2 (PF00168, IPR000008, SM00239): C2 domain
216 TBCELinteractor100LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain
LRR_9 (PF14580): Leucine-rich repeat
217 TBX6interactor100DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
T-box (PF00907, IPR001699, SM00425): T-box
218 TCEA2interactor60.267112.066Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
DUF4423 (PF14394, IPR025537): Domain of unknown function (DUF4423)
219 TCL6oncoprotein100NA
220 TCTEX1D1interactor100Tctex-1 (PF03645, IPR005334): Tctex-1 family
221 TDO2interactor200Trp_dioxygenase (PF03301, IPR004981): Tryptophan 2,3-dioxygenase
222 TGFB1suppressor30.6671.408TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide
TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
223 TICAM2interactor21.0000TIR_2 (PF13676, IPR000157): TIR domain
224 TK1oncoprotein40.33361.193TK (PF00265, IPR001267, SM00203): Thymidine kinase
225 TMEM100interactor100TMEM100 (PF16311, IPR032536): Transmembrane protein 100
226 TMOD1interactor60.7334.727Tropomodulin (PF03250, IPR004934): Tropomodulin
227 TP53BP1suppressor60.133437.15153-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
228 TPM2protein found in more fusions100.55653.142DASH_Spc19 (PF08287, IPR013251): Spc19
Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
229 TPM3oncoprotein90.53696.023Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
230 TPM4oncoprotein80.57164.572Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
231 TRAF6protein found in more fusions70.400193.926SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
232 TRIM41interactor90.42913.078BUD22 (PF09073, IPR015158): BUD22
Fer2 (PF00111, IPR001041): 2Fe-2S iron-sulfur cluster binding domain
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
RecR (PF02132, IPR023628): RecR protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
DUF3631 (PF12307, IPR022081): Protein of unknown function (DUF3631)
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
233 TRIM42interactor140.30853.460CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
234 TTC25interactor21.0000TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
SieB (PF14163, IPR025982): Super-infection exclusion protein B
TPR_19 (PF14559): Tetratricopeptide repeat
235 TTC39Boncoprotein100DUF3808 (PF10300, IPR019412): Protein of unknown function (DUF3808)
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
236 TTC9Cinteractor21.0000TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
237 TULP2interactor100Tub (PF01167, IPR000007): Tub family
Tub_N (PF16322, IPR005398): Tubby N-terminal
238 TXLNAprotein found in more fusions70.267132.878Taxilin (PF09728, IPR026183): Myosin-like coiled-coil protein
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
239 UBE3Aoncoprotein90.321208.931HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
240 UBIAD1suppressor100UbiA (PF01040, IPR000537): UbiA prenyltransferase family
241 UBL4Ainteractor60.267770.567ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
242 UBL4Binteractor100ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF4351 (PF14261, IPR025587): Domain of unknown function (DUF4351)
243 UNC45Ainteractor80.250948.160Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
TPR_16 (PF13432): Tetratricopeptide repeat
HEAT_2 (PF13646): HEAT repeats
244 USE1interactor100Use1 (PF09753, IPR019150): Membrane fusion protein Use1
245 VCPprotein found in more fusions220.1191067.871AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
246 VEZF1interactor100Chon_Sulph_att (PF06566, IPR010555): Chondroitin sulphate attachment domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
Spt20 (PF12090, IPR021950): Spt20 family
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
247 VIPinteractor100Hormone_2 (PF00123, IPR000532, SM00070): Peptide hormone
CBP_BcsR (PF10945, IPR024487): Cellulose biosynthesis protein BcsR
248 WFDC9interactor100WAP (PF00095, IPR008197, SM00217): WAP-type (Whey Acidic Protein) 'four-disulfide core'
249 XPO1interactor190.0701129.203CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
250 XRCC2interactor100Rad51 (PF08423, IPR013632): Rad51
251 ZBED4interactor200Dimer_Tnp_hAT (PF05699, IPR008906): hAT family C-terminal dimerisation region
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
252 ZDHHC17protein found in more fusions80.048495.688zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
253 ZMAT2interactor21.0000Cgr1 (PF03879, IPR005579): Cgr1 family
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
254 ZNF124interactor70.9050.205KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
255 ZNF329interactor50.4009.034zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
256 ZNF404interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
257 ZNF417interactor140.62612.765A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
258 ZNF483interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
259 ZNF564interactor40.8330.400FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
KRAB (PF01352, IPR001909, SM00349): KRAB box
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
260 ZNF572interactor70.6671.224C1_2 (PF03107, IPR004146): C1 domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
261 ZNF587interactor120.6368.983KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
262 ZNF695interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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