1 |
MT-CO2 | parental protein | 43 | 0.185 | 2097.174 | COX2 (PF00116, IPR002429): Cytochrome C oxidase subunit II, periplasmic domain COX2_TM (PF02790, IPR011759): Cytochrome C oxidase subunit II, transmembrane domain |
2 |
FTSJ3 | parental protein | 99 | 0.219 | 3187.795 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase M16C_assoc (PF08367, IPR013578): Peptidase M16C associated Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14 |
3 |
ABT1 | interactor | 2 | 1.000 | 0 | T2SS-T3SS_pil_N (PF13629, IPR032789): Pilus formation protein N terminal region |
4 |
ATAD3B | interactor | 10 | 0.400 | 19.609 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) TsaE (PF02367, IPR003442): Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523) |
5 |
ATP2B3 | interactor | 4 | 0.500 | 5.895 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase ATP_Ca_trans_C (PF12424, IPR022141): Plasma membrane calcium transporter ATPase C terminal Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
6 |
ATP5C1 | interactor | 18 | 0.542 | 32.760 | ATP-synt (PF00231, IPR000131): ATP synthase ACT_4 (PF13291, IPR002912): ACT domain |
7 |
ATP5F1 | interactor | 13 | 0.449 | 23.985 | Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105) |
8 |
BCAP31 | protein found in more fusions | 9 | 0.750 | 7.502 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) |
9 |
BRIX1 | interactor | 40 | 0.456 | 264.910 | Brix (PF04427, IPR007109, SM00879): Brix domain |
10 |
BYSL | interactor | 13 | 0.423 | 20.802 | Bystin (PF05291, IPR007955): Bystin MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1) |
11 |
CAND1 | interactor | 60 | 0.303 | 776.476 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
12 |
CANX | interactor | 20 | 0.368 | 163.500 | Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
13 |
CBX8 | interactor | 15 | 0.615 | 9.982 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RBR (PF17208): RNA binding Region CBX7_C (PF17218): CBX family C-terminal motif |
14 |
CDC5L | interactor | 33 | 0.367 | 212.311 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
15 |
CDK2 | suppressor | 30 | 0.379 | 245.195 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
16 |
CLTC | oncoprotein | 28 | 0.423 | 119.791 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
17 |
COPS5 | protein found in more fusions | 41 | 0.464 | 180.214 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
18 |
COX20 | interactor | 1 | 0 | 0 | DUF3767 (PF12597, IPR022533): Protein of unknown function (DUF3767) |
19 |
COX4I1 | interactor | 15 | 0.457 | 58.733 | COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV |
20 |
COX5B | interactor | 2 | 1.000 | 0 | COX5B (PF01215, IPR002124): Cytochrome c oxidase subunit Vb |
21 |
CSNK2A1 | oncoprotein | 30 | 0.335 | 152.879 | Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
CUL1 | suppressor | 40 | 0.451 | 186.994 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
23 |
CUL3 | protein found in more fusions | 61 | 0.304 | 694.852 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
24 |
CUL7 | protein found in more fusions | 47 | 0.320 | 726.246 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
25 |
DCAF1 | protein found in more fusions | 11 | 0.644 | 4.004 | DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
26 |
DDB1 | protein found in more fusions | 19 | 0.353 | 70.239 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
27 |
DDOST | interactor | 21 | 0.514 | 51.964 | DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta |
28 |
DDX21 | interactor | 29 | 0.468 | 106.535 | CRT10 (PF08728, IPR014839): CRT10 DEAD (PF00270, IPR011545): DEAD/DEAH box helicase GUCT (PF08152, IPR012562): GUCT (NUC152) domain Sulfatase (PF00884, IPR000917): Sulfatase MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
29 |
DDX24 | interactor | 41 | 0.541 | 129.253 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Sec62 (PF03839, IPR004728): Translocation protein Sec62 Tti2 (PF10521, IPR018870): Tti2 family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
30 |
DDX27 | interactor | 35 | 0.494 | 95.028 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
31 |
DDX56 | interactor | 33 | 0.583 | 40.348 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
32 |
DEK | oncoprotein | 14 | 0.429 | 12.716 | DEK_C (PF08766, IPR014876): DEK C terminal domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family SAP (PF02037, IPR003034, SM00513): SAP domain Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
33 |
DHX8 | protein found in more fusions | 11 | 0.622 | 2.862 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
34 |
DKC1 | oncoprotein | 36 | 0.469 | 152.752 | DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain PUA (PF01472, IPR002478, SM00359): PUA domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain |
35 |
EBNA1BP2 | interactor | 45 | 0.487 | 145.866 | Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2 |
36 |
ECT2 | suppressor | 7 | 0.286 | 35.659 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal |
37 |
EED | suppressor | 44 | 0.303 | 373.946 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
38 |
EGFR | oncoprotein | 22 | 0.262 | 164.947 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
39 |
EIF2AK2 | oncoprotein | 13 | 0.697 | 8.259 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Pkinase (PF00069, IPR000719): Protein kinase domain |
40 |
EIF2B4 | interactor | 8 | 0.643 | 7.873 | IF-2B (PF01008, IPR000649): Initiation factor 2 subunit family Mpp10 (PF04006, IPR007151): Mpp10 protein |
41 |
EIF5B | interactor | 10 | 0.422 | 20.750 | GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 MIase (PF02426, IPR026029): Muconolactone delta-isomerase NOA36 (PF06524, IPR010531): NOA36 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) IF-2 (PF11987, IPR023115): Translation-initiation factor 2 DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) GTP_EFTU_D4 (PF14578, IPR029459): Elongation factor Tu domain 4 DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632) Coilin_N (PF15862, IPR031722): Coilin N-terminus DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
42 |
ESR1 | suppressor | 34 | 0.430 | 103.818 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
43 |
FAF2 | interactor | 15 | 0.286 | 101.233 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain |
44 |
FANCG | suppressor | 3 | 0 | 77.413 | BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain Hpt (PF01627, IPR008207, SM00073): Hpt domain TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
45 |
FBL | interactor | 43 | 0.508 | 153.761 | Fibrillarin (PF01269, IPR000692): Fibrillarin |
46 |
FN1 | oncoprotein | 33 | 0.305 | 404.514 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
47 |
GNL3 | interactor | 35 | 0.600 | 68.756 | GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family FAM176 (PF14851): FAM176 family |
48 |
GNL3L | interactor | 6 | 0.667 | 0.655 | DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68) |
49 |
GPD2 | interactor | 5 | 0.300 | 5.321 | DAO (PF01266, IPR006076): FAD dependent oxidoreductase EF-hand_7 (PF13499, IPR011992): EF-hand domain pair DAO_C (PF16901, IPR031656): C-terminal domain of alpha-glycerophosphate oxidase |
50 |
GRK5 | protein found in more fusions | 11 | 0.356 | 10.711 | Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
51 |
HIST1H1A | interactor | 24 | 0.380 | 86.321 | Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
52 |
HNRNPU | interactor | 59 | 0.352 | 578.281 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
53 |
HP1BP3 | interactor | 22 | 0.494 | 36.766 | RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SDA1 (PF05285, IPR007949): SDA1 YL1 (PF05764, IPR008895): YL1 nuclear protein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family |
54 |
HSP90B1 | suppressor | 23 | 0.447 | 105.981 | CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region |
55 |
HSPB2 | interactor | 3 | 1.000 | 0 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
56 |
IFI16 | suppressor | 34 | 0.326 | 114.355 | HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
57 |
ILF2 | interactor | 39 | 0.453 | 184.746 | DZF (PF07528, IPR006561, SM00572): DZF domain |
58 |
LGR4 | interactor | 17 | 0.317 | 127.108 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
59 |
LIG4 | interactor | 2 | 1.000 | 0 | APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
60 |
LTV1 | interactor | 7 | 0.667 | 3.614 | DUF1874 (PF08960, IPR015055): Domain of unknown function (DUF1874) LTV (PF04180, IPR007307): Low temperature viability protein |
61 |
MAGEB4 | interactor | 2 | 1.000 | 0 | MAGE (PF01454, IPR002190): MAGE family Pap_E4 (PF02711, IPR003861): E4 protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
62 |
MAGT1 | interactor | 12 | 0.394 | 54.411 | OST3_OST6 (PF04756, IPR021149): OST3 / OST6 family, transporter family |
63 |
MAK16 | interactor | 6 | 0.733 | 0.732 | Mak16 (PF04874, IPR006958): Mak16 protein C-terminal region Ribosomal_L28e (PF01778, IPR029004): Ribosomal L28e protein family Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
64 |
MPHOSPH10 | interactor | 15 | 0.638 | 11.219 | Mpp10 (PF04006, IPR007151): Mpp10 protein |
65 |
MRPL58 | interactor | 18 | 0.314 | 115.851 | RF-1 (PF00472, IPR000352): RF-1 domain |
66 |
MRTO4 | interactor | 28 | 0.571 | 63.047 | Glu_syn_central (PF04898, IPR006982): Glutamate synthase central domain Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
67 |
MT-CO1 | protein found in more fusions | 4 | 0.500 | 3.000 | DUF3485 (PF11984, IPR014263): Protein of unknown function (DUF3485) |
68 |
MYBBP1A | suppressor | 32 | 0.526 | 70.794 | DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal |
69 |
NAP1L4 | protein found in more fusions | 11 | 0.622 | 3.842 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
70 |
NCSTN | interactor | 12 | 0.591 | 20.546 | Nicastrin (PF05450, IPR008710): Nicastrin Ost4 (PF10215, IPR018943): Oligosaccaryltransferase |
71 |
NDUFS1 | interactor | 14 | 0.440 | 60.238 | NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer4 (PF00037, IPR001450): 4Fe-4S binding domain Molybdopterin (PF00384, IPR006656): Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 (PF10588, IPR019574, SM00929): NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 (PF13510): 2Fe-2S iron-sulfur cluster binding domain |
72 |
NDUFV2 | interactor | 5 | 0.700 | 1.224 | 2Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin |
73 |
NELFCD | oncoprotein | 4 | 0.333 | 66.935 | TH1 (PF04858, IPR006942): TH1 protein |
74 |
NFIA | interactor | 8 | 0.821 | 0.762 | CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain |
75 |
NIFK | interactor | 41 | 0.527 | 98.878 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hNIFK_binding (PF12196, IPR021043): FHA Ki67 binding domain of hNIFK |
76 |
NLGN3 | interactor | 3 | 0.333 | 36.715 | COesterase (PF00135, IPR002018): Carboxylesterase family Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) |
77 |
NOB1 | interactor | 6 | 0.800 | 0.739 | NOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like WRNPLPNID (PF15017): Putative WW-binding domain and destruction box PIN_6 (PF17146): PIN domain of ribonuclease |
78 |
NOC2L | interactor | 27 | 0.689 | 18.632 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi Noc2 (PF03715, IPR005343): Noc2p family CEND1 (PF15677, IPR020162): Cell cycle exit and neuronal differentiation protein 1 |
79 |
NOL12 | interactor | 17 | 0.640 | 18.171 | DUF2357 (PF09823, IPR018633): Domain of unknown function (DUF2357) Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa) |
80 |
NOP2 | interactor | 56 | 0.451 | 274.473 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F P120R (PF08062, IPR012586): P120R (NUC006) repeat Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477) FAM176 (PF14851): FAM176 family Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
81 |
NOP56 | interactor | 54 | 0.428 | 232.747 | Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal |
82 |
NOP58 | interactor | 35 | 0.558 | 72.272 | Cellulose_synt (PF03552, IPR005150): Cellulose synthase Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) |
83 |
NPM1 | suppressor | 62 | 0.353 | 582.511 | Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
84 |
NSA2 | oncoprotein | 22 | 0.701 | 13.292 | Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14 |
85 |
NTRK1 | oncoprotein | 77 | 0.204 | 2075.175 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
86 |
OAS3 | interactor | 4 | 0.667 | 2.261 | NTP_transf_2 (PF01909, IPR002934): Nucleotidyltransferase domain OAS1_C (PF10421, IPR018952): 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus |
87 |
OBSL1 | interactor | 46 | 0.372 | 197.951 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
88 |
PAIP1 | interactor | 4 | 1.000 | 0 | MIF4G (PF02854, IPR003890, SM00543): MIF4G domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region |
89 |
PES1 | interactor | 37 | 0.527 | 89.000 | Pescadillo_N (PF06732, IPR010613): Pescadillo N-terminus RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
90 |
PHB | suppressor | 23 | 0.368 | 139.514 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290) |
91 |
PRR11 | interactor | 19 | 0.520 | 15.361 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
92 |
PSIP1 | oncoprotein | 11 | 0.618 | 4.104 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif BEX (PF04538, IPR021156): Brain expressed X-linked like family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PGA2 (PF07543, IPR011431): Protein trafficking PGA2 PWWP (PF00855, IPR000313, SM00293): PWWP domain LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF) TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 |
93 |
PSMA1 | interactor | 7 | 0.400 | 29.699 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
94 |
PSMC2 | interactor | 13 | 0.439 | 34.392 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
95 |
PSMC4 | interactor | 8 | 0.643 | 11.143 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain |
96 |
PUM3 | interactor | 37 | 0.593 | 59.466 | CPL (PF08144, IPR012959): CPL (NUC119) domain |
97 |
PWP1 | interactor | 18 | 0.556 | 16.012 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
98 |
RAB1B | oncoprotein | 6 | 0.667 | 3.395 | Ras (PF00071, IPR001806, SM00173): Ras family |
99 |
RAD21 | oncoprotein | 13 | 0.359 | 80.965 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
100 |
RBM14 | suppressor | 18 | 0.438 | 34.207 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
101 |
RBM19 | interactor | 10 | 0.533 | 7.251 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A Integrase_AP2 (PF14657, IPR028259): AP2-like DNA-binding integrase domain |
102 |
RBM34 | oncoprotein | 18 | 0.490 | 21.654 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3139 (PF11337, IPR021486): Protein of unknown function (DUF3139) |
103 |
RBM4B | interactor | 7 | 0.571 | 2.282 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC (PF00098, IPR001878): Zinc knuckle |
104 |
RIDA | interactor | 2 | 0 | 0 | Ribonuc_L-PSP (PF01042, IPR006175): Endoribonuclease L-PSP |
105 |
RNF2 | interactor | 52 | 0.244 | 636.037 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
106 |
RPF2 | interactor | 26 | 0.609 | 35.308 | Brix (PF04427, IPR007109, SM00879): Brix domain |
107 |
RPL10 | suppressor | 47 | 0.440 | 239.364 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
108 |
RPL14 | interactor | 44 | 0.537 | 114.060 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family |
109 |
RPL18A | interactor | 31 | 0.680 | 19.784 | Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A |
110 |
RPL31 | interactor | 27 | 0.621 | 22.836 | Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e |
111 |
RPL39 | interactor | 3 | 1.000 | 0 | Ribosomal_L39 (PF00832, IPR000077): Ribosomal L39 protein |
112 |
RPL4 | interactor | 36 | 0.590 | 96.009 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
113 |
RPL5 | suppressor | 46 | 0.514 | 175.195 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
114 |
RPL6 | protein found in more fusions | 42 | 0.537 | 149.302 | Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain |
115 |
RPL8 | interactor | 34 | 0.633 | 37.329 | Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain |
116 |
RPL9 | interactor | 29 | 0.640 | 67.811 | Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6 |
117 |
RPN1 | oncoprotein | 28 | 0.370 | 177.535 | Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain |
118 |
RRS1 | interactor | 37 | 0.473 | 135.464 | GRP (PF07172, IPR010800): Glycine rich protein family RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 RRS1 (PF04939, IPR007023): Ribosome biogenesis regulatory protein (RRS1) |
119 |
SAT1 | protein found in more fusions | 3 | 1.000 | 0 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family |
120 |
SDHB | suppressor | 13 | 0.359 | 72.259 | Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain Fer4_17 (PF13534): 4Fe-4S dicluster domain |
121 |
SET | oncoprotein | 7 | 0.400 | 3.578 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
122 |
SF3B6 | interactor | 8 | 0.536 | 3.120 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
123 |
SIRT7 | interactor | 58 | 0.276 | 627.426 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
124 |
SLC25A3 | interactor | 22 | 0.411 | 132.306 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
125 |
SRP68 | interactor | 14 | 0.571 | 11.044 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB SRP68 (PF16969, IPR026258): RNA-binding signal recognition particle 68 |
126 |
SRP72 | interactor | 16 | 0.608 | 16.862 | BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat |
127 |
SRPK3 | interactor | 11 | 0.618 | 3.629 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Pkinase (PF00069, IPR000719): Protein kinase domain |
128 |
SSR1 | interactor | 15 | 0.457 | 70.381 | TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
129 |
SSR4 | interactor | 16 | 0.417 | 132.510 | TRAP-delta (PF05404, IPR008855): Translocon-associated protein, delta subunit precursor (TRAP-delta) OppC_N (PF12911, IPR025966): N-terminal TM domain of oligopeptide transport permease C |
130 |
SURF2 | interactor | 4 | 0.833 | 0.080 | SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
131 |
TBL3 | interactor | 20 | 0.611 | 26.167 | SdiA-regulated (PF06977, IPR009722): SdiA-regulated Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
132 |
TSR1 | interactor | 16 | 0.417 | 51.442 | AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein |
133 |
U2AF1 | oncoprotein | 21 | 0.467 | 43.908 | DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509) KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
134 |
UBE2O | protein found in more fusions | 8 | 0.286 | 25.295 | BUD22 (PF09073, IPR015158): BUD22 UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 |
135 |
UQCRC2 | oncoprotein | 22 | 0.420 | 99.955 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
136 |
UTP14A | interactor | 27 | 0.370 | 165.320 | Utp14 (PF04615, IPR006709): Utp14 protein |
137 |
VDAC1 | interactor | 17 | 0.566 | 42.403 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
138 |
VDAC2 | interactor | 20 | 0.447 | 113.621 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
139 |
VDAC3 | interactor | 22 | 0.403 | 121.573 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
140 |
WDR12 | interactor | 15 | 0.670 | 9.143 | NLE (PF08154, IPR012972): NLE (NUC135) domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
141 |
YME1L1 | interactor | 5 | 0.700 | 3.685 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Peptidase_M41 (PF01434, IPR000642): Peptidase family M41 |
142 |
YWHAE | oncoprotein | 15 | 0.600 | 43.497 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
143 |
ZC3H3 | interactor | 13 | 0.551 | 8.225 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c CCDC24 (PF15669, IPR031367): Coiled-coil domain-containing protein 24 family |
144 |
ZNF622 | interactor | 10 | 0.694 | 5.713 | S-antigen (PF05756, IPR008825): S-antigen protein Stm1_N (PF09598, IPR019084): Stm1 TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) |