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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)114
The number (and %) of the onco-proteins39 (34.21 %)
The number (and %) of the tumor suppressors20 (17.54 %)
Total number of binary PPIs (saturation %)790 (12.27 %)
The number (and %) of affected PPIs119 (15.06 %)
The number of possible different fusions20
PPI diameter4
PPI radius2
The average degree of PPI13.053
Assortativity coefficient-0.2240
The network average Clustering coefficient0.549
The number (and %) of a zero Clustering coefficients13 (11.40 %)
The number (and %) of a zero Betweenness Centrality27 (23.68 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RFWD2,CKS1B All fusions
Proteins found in more fusions PTPN11 (see 1 fusions); CUL4A (see 4 fusions); FOXO1 (see 3 fusions); HSP90AA1 (see 6 fusions); SFN (see 1 fusions); DCAF1 (see 1 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); MDM4 (see 2 fusions); MVP (see 2 fusions); UBE2D2 (see 1 fusions); IKZF1 (see 1 fusions); MIPOL1 (see 1 fusions); YWHAZ (see 5 fusions); FOS (see 4 fusions); COPS5 (see 1 fusions); CDC37 (see 2 fusions); DDB1 (see 4 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RFWD2parental protein760.1503895.022Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
IncA (PF04156, IPR007285): IncA protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
WD40_like (PF17005, IPR031544): WD40-like domain
2 CKS1Bparental protein430.1392807.112CKS (PF01111, IPR000789, SM01084): Cyclin-dependent kinase regulatory subunit
3 ARID5Aoncoprotein100ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
4 ATF6interactor31.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749)
5 BTBD2interactor100.7785.802BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PHR (PF08005, IPR012983): PHR domain
6 CCNA1interactor120.8334.545Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
7 CCNA2oncoprotein180.62591.291Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
8 CCNB1oncoprotein120.54544.689Adeno_E1A (PF02703, IPR003853): Early E1A protein
Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
9 CCNB2interactor51.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
10 CCT2interactor170.65447.917Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
11 CCT3interactor150.676113.871Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
12 CCT4interactor170.654108.985Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
13 CCT5interactor150.74318.556Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
14 CCT6Ainteractor140.78017.249Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
15 CCT7interactor150.74320.801Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
16 CCT8interactor150.79010.954Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
17 CDC20oncoprotein210.479122.879WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
18 CDC27oncoprotein70.8670.536TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
19 CDC37protein found in more fusions60.6003.269CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
20 CDK1oncoprotein220.410139.552Pkinase (PF00069, IPR000719): Protein kinase domain
21 CDK2suppressor350.344418.468Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
22 CDK3interactor120.8942.289Pkinase (PF00069, IPR000719): Protein kinase domain
23 CDKN1Asuppressor300.303491.860CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
24 CDKN1Bsuppressor230.462239.267CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
25 CDX4interactor100Caudal_act (PF04731, IPR006820): Caudal like protein activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
26 CKS1BP7oncoprotein31.0000NA
27 COPS2suppressor220.68821.826YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
28 COPS3interactor260.63434.911RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
29 COPS4interactor270.59862.948DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
30 COPS5protein found in more fusions500.331861.393JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
31 COPS6interactor390.410646.963DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
32 COPS7Ainteractor220.76610.921PCI (PF01399, IPR000717, SM00088): PCI domain
33 COPS7Binteractor200.75814.128PCI (PF01399, IPR000717, SM00088): PCI domain
34 COPS8interactor200.8424.778CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
35 CRTC2oncoprotein40.5003.483TORC_N (PF12884, IPR024783): Transducer of regulated CREB activity, N terminus
TORC_M (PF12885, IPR024784): Transducer of regulated CREB activity middle domain
TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus
36 CUL1suppressor380.353544.455Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
37 CUL2suppressor200.58939.749Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
38 CUL3protein found in more fusions390.340277.026Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
39 CUL4Aprotein found in more fusions320.518109.829Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
40 CUL4Boncoprotein290.517115.690Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
41 DCAF1protein found in more fusions170.8009.000DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
LisH (PF08513, IPR013720, SM00667): LisH
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
42 DCAF11interactor111.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
43 DDA1interactor190.77813.454DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
44 DDB1protein found in more fusions270.59184.985CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
45 DDB2suppressor240.56155.677WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
46 DET1interactor130.35955.127Det1 (PF09737, IPR019138): De-etiolated protein 1 Det1
47 DMC1interactor200Rad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
48 DUSP1suppressor21.0000DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
49 ELAVL1oncoprotein230.273404.191RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
50 ERCC8oncoprotein170.77215.843WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4859 (PF16151, IPR032339): Domain of unknown function (DUF4859)
51 ETS1oncoprotein50.7003.273Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
52 ETS2suppressor60.6003.918Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
53 ETV1oncoprotein50.4003.654Ets (PF00178, IPR000418, SM00413): Ets-domain
ETS_PEA3_N (PF04621, IPR006715): PEA3 subfamily ETS-domain transcription factor N terminal domain
54 ETV4oncoprotein21.0000Ets (PF00178, IPR000418, SM00413): Ets-domain
ETS_PEA3_N (PF04621, IPR006715): PEA3 subfamily ETS-domain transcription factor N terminal domain
55 ETV5oncoprotein40.5003.022Ets (PF00178, IPR000418, SM00413): Ets-domain
ETS_PEA3_N (PF04621, IPR006715): PEA3 subfamily ETS-domain transcription factor N terminal domain
56 FOSoncoprotein110.28925.261bZIP_1 (PF00170, IPR004827): bZIP transcription factor
57 FOSL2oncoprotein70.3818.123bZIP_1 (PF00170, IPR004827): bZIP transcription factor
58 FOXO1suppressor70.40021.281K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2
FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
59 FZR1suppressor130.52651.620WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
60 GDPGP1interactor208.487NA
61 HSP90AA1oncoprotein290.360326.479HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
62 HSPA2interactor50.8002.853HSP70 (PF00012, IPR013126): Hsp70 protein
63 HSPA6interactor60.8671.026HSP70 (PF00012, IPR013126): Hsp70 protein
64 HSPA8oncoprotein210.46799.087HSP70 (PF00012, IPR013126): Hsp70 protein
65 IKZF1suppressor200Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
66 JUNoncoprotein150.297121.500bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
67 JUNBoncoprotein30.6670.286bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
68 JUNDoncoprotein70.57114.057bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
69 KIAA0368interactor30.3334.398HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
Ecm29 (PF13001, IPR024372): Proteasome stabiliser
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
70 KLHL42interactor61.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
71 KRTAP10-9interactor31.0000Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
72 KRTAP5-9interactor21.0000Ery_res_leader2 (PF08057, IPR012559): Erythromycin resistance leader peptide
73 LDHBinteractor110.40067.467Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
74 LRR1interactor130.9101.325LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
75 MDM2oncoprotein230.355126.663Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
76 MDM4oncoprotein120.49119.114zf-FLZ (PF04570, IPR007650): zinc-finger of the FCS-type, C2-C2
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
77 MEOX1interactor2013.934Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
78 MIPOL1protein found in more fusions306.372Bac_globin (PF01152, IPR001486): Bacterial-like globin
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Rho_Binding (PF08912, IPR015008): Rho Binding
IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D
79 MVPoncoprotein90.179180.528Vault (PF01505, IPR002499): Major Vault Protein repeat
DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543)
MVP_shoulder (PF11978, IPR021870): Shoulder domain
80 PARP4interactor21.0000BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
81 PSMD9interactor40.6679.218Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
PDZ_2 (PF13180, IPR001478): PDZ domain
82 PTPN1suppressor21.0000Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
83 PTPN11suppressor31.0000SH2 (PF00017, IPR000980, SM00252): SH2 domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
84 RB1CC1suppressor21.0000Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II
DHC (PF09626, IPR018588): Dihaem cytochrome c
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
ATG11 (PF10377, IPR019460): Autophagy-related protein 11
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Jag_N (PF14804, IPR032782): Jag N-terminus
NPBW (PF15180, IPR013297): Neuropeptides B and W
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain
85 RBX1oncoprotein290.503100.956zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
86 RCHY1suppressor80.7141.651C1_2 (PF03107, IPR004146): C1 domain
zf-CHY (PF05495, IPR008913): CHY zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zinc_ribbon_6 (PF14599): Zinc-ribbon
87 REG1Ainteractor100Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
88 RELoncoprotein30.33316.399RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
89 ROPN1interactor200RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
90 SEPT3interactor200Septin (PF00735, IPR000038): Septin
91 SFNsuppressor80.5248.17414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
92 SIPA1oncoprotein201.914IncA (PF04156, IPR007285): IncA protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
93 SKP1oncoprotein210.557181.584Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
94 SKP2suppressor270.379374.090LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
95 SPERTinteractor200ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Chibby (PF14645, IPR028118): Chibby family
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
96 SSBP1interactor110.62223.998SSB (PF00436, IPR000424): Single-strand binding protein family
97 STK40interactor100.26751.053Pkinase (PF00069, IPR000719): Protein kinase domain
Kinase-like (PF14531, IPR027916): Kinase-like
98 SUMO1P1interactor200NA
99 TCEB2interactor91.0000ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
100 TCF4suppressor40.50022.643CDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
101 TCP1interactor160.74220.414Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
102 TP53suppressor450.209831.410DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
103 TRIB1interactor50.6006.517Pkinase (PF00069, IPR000719): Protein kinase domain
104 TRIB2interactor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
105 TRIB3interactor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
106 TRIM27oncoprotein90.39354.999IncA (PF04156, IPR007285): IncA protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
107 TRIM49interactor41.0000A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
108 UBE2D1interactor150.33075.862UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
109 UBE2D2oncoprotein130.39452.064UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
110 WDR5interactor70.8570.324WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
111 XIAPinteractor70.20035.462BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
112 YWHABinteractor90.41726.97714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
113 YWHAZprotein found in more fusions150.40739.27014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
114 ZNF397interactor21.0000SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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