Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins U2AF2 (from a repository: Sun Dec 4 04:23:02 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 349 The number (and %) of the onco-proteins 115 (32.95 %) The number (and %) of the tumor suppressors 40 (11.46 %) Total number of binary PPIs (saturation %) 6157 (10.14 %) The number (and %) of affected PPIs 349 (5.67 %) The number of possible different fusions 77 PPI diameter 2 PPI radius 1 The average degree of PPI 34.579 Assortativity coefficient -0.2348 The network average Clustering coefficient 0.465 The number (and %) of a zero Clustering coefficients 6 (1.72 %) The number (and %) of a zero Betweenness Centrality 19 (5.44 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: U2AF2	All fusions : CN409107;
Proteins found in more fusions	PRPF19 (see 2 fusions); U2AF2 (see 2 fusions); RPL37A/PRPF8 (see 1 fusions); SLC9A3R1 (see 2 fusions); RANGAP1 (see 2 fusions); UBA1 (see 2 fusions); PRDX1 (see 1 fusions); DDX5 (see 1 fusions); HUWE1 (see 2 fusions); EEF1D (see 3 fusions); HNRNPD (see 1 fusions); RBFOX2 (see 2 fusions); EZR (see 2 fusions); POLR2A (see 2 fusions); DDX17 (see 3 fusions); NCL (see 3 fusions); HSPA8/HSPD1 (see 1 fusions); EEF1A1 (see 1 fusions); CUL3 (see 1 fusions); AHNAK (see 2 fusions); MAPRE1 (see 1 fusions); COPS5 (see 1 fusions); LUC7L2 (see 2 fusions); TRIM28 (see 1 fusions); KPNB1 (see 2 fusions); ATXN1 (see 3 fusions); RACK1 (see 3 fusions); HNRNPC (see 1 fusions); NTRK1/TPR (see 1 fusions); AES (see 3 fusions); HSP90AA1/GNAI2 (see 1 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); HNRNPA3/NONO (see 1 fusions); EWSR1 (see 2 fusions); PRKDC (see 3 fusions); YWHAZ (see 1 fusions); HMGB1/HMGB2 (see 1 fusions); PCNA (see 1 fusions); STAT1 (see 1 fusions); PRPF3 (see 1 fusions); SUZ12 (see 2 fusions); SNW1 (see 1 fusions); PTBP1 (see 1 fusions); SRSF2 (see 1 fusions); VCP (see 4 fusions); TKT (see 5 fusions); HSP90AA1 (see 2 fusions); SFPQ (see 6 fusions); HSP90AB1 (see 1 fusions); SRPK2 (see 1 fusions); HINT1 (see 3 fusions); LUC7L (see 1 fusions); CALR (see 6 fusions); IMPDH2 (see 2 fusions); SNRNP200 (see 3 fusions); PRPF8 (see 3 fusions); PRPF6 (see 1 fusions); QKI (see 3 fusions); EZH2 (see 1 fusions); CDC37 (see 2 fusions); RBMX (see 3 fusions); CUL7 (see 2 fusions); MDH2 (see 1 fusions); PRPF40A (see 2 fusions); PUF60 (see 2 fusions); NCOA5 (see 1 fusions); PABPC1 (see 2 fusions); SERBP1 (see 1 fusions); HNRNPL (see 2 fusions); KHDRBS1 (see 1 fusions); SF1 (see 1 fusions); MCM2 (see 1 fusions); SRSF1 (see 1 fusions); CFL1/EED (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	U2AF2	parental protein	349	0.094	46692.177	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
2	ACIN1	interactor	41	0.440	79.129	Calc_CGRP_IAPP (PF00214, IPR021116): Calcitonin / CGRP / IAPP family CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family FAM27 (PF15832, IPR031672): FAM27 D and E protein family DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) RSB_motif (PF16294, IPR032552): RNSP1-SAP18 binding (RSB) motif SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
3	AES	protein found in more fusions	11	0.244	15.024	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
4	AHNAK	suppressor	24	0.435	36.914	DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945) ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993) DUF4097 (PF13349, IPR025164): Putative adhesin Ntox37 (PF15535, IPR029108): Bacterial toxin 37
5	AK2	interactor	8	0.714	2.306	ADK (PF00406, IPR000850): Adenylate kinase AAA_33 (PF13671): AAA domain
6	ALYREF	interactor	42	0.483	76.005	FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
7	ANP32A	suppressor	10	0.444	9.029	SDA1 (PF05285, IPR007949): SDA1 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_9 (PF14580): Leucine-rich repeat
8	ANXA1	suppressor	12	0.527	6.083	Annexin (PF00191, IPR018502, SM00335): Annexin
9	ANXA2	interactor	19	0.497	20.358	Annexin (PF00191, IPR018502, SM00335): Annexin
10	ANXA5	oncoprotein	12	0.470	8.498	Annexin (PF00191, IPR018502, SM00335): Annexin
11	ANXA6	interactor	6	0.733	1.486	Annexin (PF00191, IPR018502, SM00335): Annexin
12	APBB1	interactor	27	0.277	63.807	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
13	APOA1	interactor	3	1.000	0	ApoA-II (PF04711, IPR006801): Apolipoprotein A-II (ApoA-II) Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1)
14	ARHGDIA	interactor	20	0.386	39.373	Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
15	ARHGDIB	interactor	3	0.667	0.667	Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
16	ARPC1B	interactor	6	0.600	2.619	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
17	ATIC	oncoprotein	12	0.439	8.747	AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme MGS (PF02142, IPR011607, SM00851): MGS-like domain
18	ATXN1	protein found in more fusions	14	0.282	32.186	AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) Spt20 (PF12090, IPR021950): Spt20 family ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
19	BARD1	suppressor	47	0.274	169.273	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
20	BCAS2	interactor	29	0.559	27.904	BCAS2 (PF05700, IPR008409): Breast carcinoma amplified sequence 2 (BCAS2) ZapB (PF06005, IPR009252): Cell division protein ZapB
21	BEND7	interactor	2	0	0	BEN (PF10523, IPR018379, SM01025): BEN domain
22	CALCOCO2	interactor	7	0.467	4.467	bZIP_1 (PF00170, IPR004827): bZIP transcription factor CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding zf-C2H2_4 (PF13894): C2H2-type zinc finger
23	CALM1	interactor	24	0.406	26.730	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
24	CALR	oncoprotein	28	0.413	53.441	Calreticulin (PF00262, IPR001580): Calreticulin family DDHD (PF02862, IPR004177, SM01127): DDHD domain
25	CAND1	interactor	130	0.259	1169.508	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
26	CANX	interactor	28	0.455	38.277	Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
27	CAP1	interactor	11	0.467	7.338	CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
28	CAPZB	interactor	10	0.600	1.256	Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
29	CCAR1	suppressor	12	0.424	6.868	Cucumo_2B (PF03263, IPR004946): Cucumovirus protein 2B DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) IncA (PF04156, IPR007285): IncA protein Presenilin (PF01080, IPR001108): Presenilin SAP (PF02037, IPR003034, SM00513): SAP domain FimP (PF09766, IPR019163): Fms-interacting protein DBC1 (PF14443, IPR025954, SM01122): DBC1 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) S1-like (PF14444, IPR025223): S1-like DUF4481 (PF14800, IPR028054): Domain of unknown function (DUF4481) FAM176 (PF14851): FAM176 family
30	CCT2	interactor	31	0.488	56.163	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
31	CCT6A	interactor	19	0.556	19.880	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
32	CCT8	interactor	18	0.641	10.359	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
33	CDC37	protein found in more fusions	29	0.312	82.123	CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
34	CDC5L	interactor	115	0.280	1135.079	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
35	CDV3	interactor	5	0.700	1.900	TraT (PF05818, IPR008874): Enterobacterial TraT complement resistance protein CDV3 (PF15359, IPR026806): Carnitine deficiency-associated protein 3
36	CERK	interactor	4	0.833	0.286	DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
37	CFL1	protein found in more fusions	26	0.335	75.049	Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
38	CHD8	oncoprotein	9	0.500	4.569	BUD22 (PF09073, IPR015158): BUD22 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
39	CHERP	interactor	20	0.537	14.328	CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. G-patch (PF01585, IPR000467, SM00443): G-patch domain HpaP (PF09483, IPR013390): Type III secretion protein (HpaP) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TP2 (PF01254, IPR000678): Nuclear transition protein 2 Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain Surp (PF01805, IPR000061, SM00648): Surp module
40	CHIC2	oncoprotein	2	1.000	0	Erf4 (PF10256, IPR019383): Golgin subfamily A member 7/ERF4 family
41	CHTOP	interactor	8	0.643	0.552	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) Lamprin (PF06403, IPR009437): Lamprin FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
42	CLIC1	interactor	8	0.607	3.908	GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
43	CLTC	oncoprotein	30	0.425	55.336	Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link
44	CNN2	interactor	5	0.500	2.744	Calponin (PF00402, IPR000557): Calponin family repeat CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
45	COPS5	protein found in more fusions	128	0.240	1222.862	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
46	CORO1A	oncoprotein	3	0.667	1.000	DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat
47	COX7A2L	interactor	2	1.000	0	COX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
48	CPSF6	interactor	26	0.495	19.950	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1
49	CUL1	suppressor	119	0.261	1121.947	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
50	CUL3	protein found in more fusions	167	0.204	2612.990	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
51	CUL5	suppressor	85	0.284	493.174	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
52	CUL7	protein found in more fusions	178	0.144	3801.323	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
53	DACH1	suppressor	4	0.667	0.500	DUF508 (PF04370, IPR007465): Domain of unknown function (DUF508) Pap_E4 (PF02711, IPR003861): E4 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family Macoilin (PF09726, IPR019130): Transmembrane protein SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
54	DARS	interactor	14	0.560	6.698	tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
55	DDX17	protein found in more fusions	52	0.468	102.611	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
56	DDX21	interactor	44	0.388	103.560	CRT10 (PF08728, IPR014839): CRT10 DEAD (PF00270, IPR011545): DEAD/DEAH box helicase GUCT (PF08152, IPR012562): GUCT (NUC152) domain Sulfatase (PF00884, IPR000917): Sulfatase MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
57	DDX39B	interactor	20	0.500	13.872	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
58	DDX3X	suppressor	44	0.378	107.241	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
59	DDX5	oncoprotein	69	0.424	206.728	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
60	DHX15	interactor	62	0.418	240.978	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain
61	DHX9	oncoprotein	74	0.397	296.856	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
62	DPPA2	interactor	3	1.000	0	SAP (PF02037, IPR003034, SM00513): SAP domain DCR (PF14047, IPR025891): Dppa2/4 conserved region Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates
63	DVL2	interactor	11	0.400	14.908	DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
64	DYNC1H1	interactor	29	0.355	71.893	AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5
65	EED	suppressor	121	0.213	1185.828	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
66	EEF1A1	suppressor	68	0.319	343.464	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
67	EEF1A1P5	interactor	3	0.667	0.087	NA
68	EEF1D	protein found in more fusions	25	0.460	24.734	EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
69	EEF2	interactor	46	0.408	140.099	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
70	EFTUD2	interactor	56	0.472	122.742	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
71	EIF3A	oncoprotein	16	0.475	10.369	DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003) Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region PCI (PF01399, IPR000717, SM00088): PCI domain AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
72	EIF4A1	interactor	24	0.547	29.681	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
73	EIF4A3	interactor	97	0.328	646.700	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
74	EIF4H	interactor	15	0.514	9.350	eIF-4B (PF06273, IPR010433): Plant specific eukaryotic initiation factor 4B RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
75	EIF5A	interactor	13	0.603	4.805	EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
76	ELAVL1	oncoprotein	105	0.205	1800.220	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
77	EPRS	interactor	24	0.446	34.270	GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
78	ESR1	suppressor	119	0.187	1448.586	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
79	ESYT1	interactor	3	0.667	0.045	C2 (PF00168, IPR000008, SM00239): C2 domain SMP_LBD (PF17047, IPR031468): Synaptotagmin-like mitochondrial-lipid-binding domain
80	EVL	oncoprotein	7	0.467	3.218	VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain WH1 (PF00568, IPR000697, SM00461): WH1 domain
81	EWSR1	oncoprotein	97	0.217	1329.102	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
82	EZH2	suppressor	58	0.255	242.410	CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
83	EZR	protein found in more fusions	27	0.345	85.952	DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
84	FABP5	interactor	11	0.673	6.125	Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
85	FAM107B	interactor	2	1.000	0	DUF1151 (PF06625, IPR009533): Protein of unknown function (DUF1151) SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
86	FBL	interactor	36	0.503	38.497	Fibrillarin (PF01269, IPR000692): Fibrillarin
87	FLOT1	interactor	8	0.571	3.111	CrtC (PF07143, IPR010791): CrtC N-terminal lipocalin domain Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family Flot (PF15975, IPR031905): Flotillin
88	FLOT2	interactor	9	0.500	6.096	YjbH (PF06082, IPR010344): Exopolysaccharide biosynthesis protein YbjH Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family Flot (PF15975, IPR031905): Flotillin
89	FUBP1	oncoprotein	22	0.446	38.336	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
90	GANAB	suppressor	16	0.475	23.321	Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31 Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like DUF5110 (PF17137): Domain of unknown function (DUF5110)
91	GBP1	suppressor	1	0	0	GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
92	GBP2	interactor	2	1.000	0	GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
93	GDI2	interactor	8	0.571	2.414	GDI (PF00996, IPR018203): GDP dissociation inhibitor
94	GIGYF2	interactor	14	0.560	4.387	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
95	GLIS2	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
96	GLUD1	interactor	6	0.667	0.118	ELFV_dehydrog (PF00208, IPR006096, SM00839): Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SF3b10 (PF07189, IPR009846): Splicing factor 3B subunit 10 (SF3b10)
97	GMFG	interactor	1	0	0	Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
98	GNAI2	oncoprotein	9	0.472	4.310	G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
99	GOT2	oncoprotein	5	0.700	0.759	Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
100	GPI	interactor	10	0.556	6.533	PGI (PF00342, IPR001672): Phosphoglucose isomerase
101	H2AFJ	interactor	3	1.000	0	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
102	HCLS1	interactor	3	0.667	1.000	HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) TMEM210 (PF15195, IPR028123): TMEM210 family SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
103	HDGF	interactor	37	0.321	69.971	PWWP (PF00855, IPR000313, SM00293): PWWP domain
104	HINT1	suppressor	14	0.423	20.087	HIT (PF01230, IPR001310): HIT domain
105	HK1	interactor	6	0.667	1.184	Hexokinase_1 (PF00349, IPR022672): Hexokinase Hexokinase_2 (PF03727, IPR022673): Hexokinase
106	HLA-DMA	interactor	1	0	0	MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
107	HMGB1	oncoprotein	10	0.400	10.558	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
108	HMGB2	protein found in more fusions	6	0.600	1.625	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
109	HN1L	interactor	2	1.000	0	JUPITER (PF17054): Microtubule-Associated protein Jupiter
110	HNRNPA0	interactor	43	0.602	48.203	SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
111	HNRNPA1	interactor	114	0.305	907.779	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
112	HNRNPA2B1	oncoprotein	49	0.476	118.037	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
113	HNRNPA3	oncoprotein	48	0.505	77.318	IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
114	HNRNPAB	interactor	35	0.541	48.664	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
115	HNRNPC	protein found in more fusions	56	0.459	122.310	APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
116	HNRNPD	oncoprotein	58	0.428	161.768	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head
117	HNRNPDL	interactor	44	0.532	70.330	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
118	HNRNPF	interactor	44	0.566	66.672	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
119	HNRNPH1	oncoprotein	54	0.512	112.597	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
120	HNRNPK	oncoprotein	83	0.383	431.341	ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain
121	HNRNPL	protein found in more fusions	48	0.515	84.583	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
122	HNRNPM	interactor	74	0.388	265.621	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
123	HNRNPR	interactor	72	0.449	234.364	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
124	HNRNPU	interactor	101	0.336	623.270	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
125	HSP90AA1	oncoprotein	61	0.324	329.089	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
126	HSP90AB1	oncoprotein	53	0.353	215.723	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
127	HSP90B1	suppressor	33	0.420	60.332	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
128	HSPA1A	interactor	34	0.460	75.938	HSP70 (PF00012, IPR013126): Hsp70 protein
129	HSPA5	oncoprotein	71	0.349	383.877	HSP70 (PF00012, IPR013126): Hsp70 protein
130	HSPA8	oncoprotein	49	0.359	235.101	HSP70 (PF00012, IPR013126): Hsp70 protein
131	HSPA9	oncoprotein	32	0.466	50.929	HSP70 (PF00012, IPR013126): Hsp70 protein
132	HSPD1	suppressor	37	0.452	107.539	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
133	HSPE1	interactor	28	0.265	119.211	Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
134	HSPH1	oncoprotein	24	0.449	42.890	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
135	HUWE1	oncoprotein	102	0.165	1347.229	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
136	IFI16	suppressor	25	0.197	98.061	HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
137	IK	interactor	30	0.498	43.528	Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
138	IL7R	interactor	45	0.280	98.252	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
139	ILF2	interactor	61	0.461	118.411	DZF (PF07528, IPR006561, SM00572): DZF domain
140	ILF3	oncoprotein	68	0.403	250.556	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain
141	IMPDH2	protein found in more fusions	13	0.697	1.396	IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
142	IQGAP1	interactor	30	0.359	89.724	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain
143	KHDRBS1	protein found in more fusions	35	0.535	44.371	KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
144	KHDRBS3	interactor	10	0.583	4.939	KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
145	KHSRP	interactor	24	0.493	15.270	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain
146	KIAA0907	interactor	7	0.476	1.221	NA
147	KIAA1429	interactor	10	0.533	5.315	Mpp10 (PF04006, IPR007151): Mpp10 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus VIR_N (PF15912, IPR031801): Virilizer, N-terminal
148	KIFC1	interactor	2	1.000	0	APG6 (PF04111, IPR007243): Autophagy protein Apg6 IncA (PF04156, IPR007285): IncA protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit Microtub_bd (PF16796, IPR031852): Microtubule binding
149	KPNB1	protein found in more fusions	34	0.330	134.029	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat
150	LAMB3	interactor	4	0.667	0.318	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Laminin_II (PF06009, IPR010307): Laminin Domain II Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI) Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase SOAR (PF16533, IPR032393): STIM1 Orai1-activating region
151	LAP3	interactor	9	0.444	5.900	Peptidase_M17 (PF00883, IPR000819): Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N (PF02789, IPR008283): Cytosol aminopeptidase family, N-terminal domain PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW
152	LARP1	interactor	29	0.485	31.901	La (PF05383, IPR006630, SM00715): La domain Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
153	LASP1	oncoprotein	8	0.286	14.333	LIM (PF00412, IPR001781, SM00132): LIM domain Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat SH3_9 (PF14604, IPR001452): Variant SH3 domain
154	LCP1	oncoprotein	4	0.833	0.182	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
155	LGALS1	interactor	12	0.379	22.687	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
156	LRRC59	interactor	10	0.644	0.930	Hid1 (PF12722): High-temperature-induced dauer-formation protein LRR_8 (PF13855, IPR001611): Leucine rich repeat DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366)
157	LRRFIP1	oncoprotein	9	0.500	5.513	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 LRRFIP (PF09738, IPR019139): LRRFIP family RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region Coilin_N (PF15862, IPR031722): Coilin N-terminus
158	LSP1	interactor	1	0	0	Caldesmon (PF02029, IPR006018): Caldesmon
159	LUC7L	protein found in more fusions	31	0.437	45.468	LUC7 (PF03194, IPR004882): LUC7 N_terminus Hid1 (PF12722): High-temperature-induced dauer-formation protein
160	LUC7L2	protein found in more fusions	51	0.409	127.549	LUC7 (PF03194, IPR004882): LUC7 N_terminus Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
161	LURAP1	interactor	1	0	0	LURAP (PF14854): Leucine rich adaptor protein DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
162	MAPRE1	oncoprotein	18	0.353	26.830	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
163	MATR3	interactor	58	0.425	168.804	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A
164	MCM2	oncoprotein	133	0.158	2433.408	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
165	MDH2	protein found in more fusions	10	0.528	3.883	Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
166	MDM2	oncoprotein	54	0.274	313.867	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
167	MSN	oncoprotein