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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CHRM3, FAM179B (from a repository: Sat Aug 24 07:13:12 2019)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins3 (37.50 %)
The number (and %) of the tumor suppressors2 (25.00 %)
Total number of binary PPIs (saturation %)9 (32.14 %)
The number (and %) of affected PPIs6 (66.67 %)
The number of possible different fusions4
PPI diameter2
PPI radiusinf
The average degree of PPI1.500
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients8 (100.00 %)
The number (and %) of a zero Betweenness Centrality6 (75.00 %)


List of the fusions

PPI for parental proteins: FAM179B,CHRM3 All fusions
Proteins found in more fusions ARF1 (see 2 fusions); SET (see 1 fusions); SRPK2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 FAM179Bparental protein202.000Dopey_N (PF04118, IPR007249): Dopey, N-terminal
DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
HEAT (PF02985, IPR000357): HEAT repeat
CLASP_N (PF12348, IPR024395): CLASP N terminal
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_2 (PF13646): HEAT repeats
2 CHRM3parental protein4012.0007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
GWT1 (PF06423, IPR009447): GWT1
3 ARF1suppressor200Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
4 ARF6oncoprotein100Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
5 CEP104interactor100ATP-synt_E_2 (PF08112, IPR012508): ATP synthase epsilon subunit
zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
HEAT (PF02985, IPR000357): HEAT repeat
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
UVR (PF02151, IPR001943): UvrB/uvrC motif
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
CLASP_N (PF12348, IPR024395): CLASP N terminal
DZR (PF12773, IPR025874): Double zinc ribbon
zf-C2H2_4 (PF13894): C2H2-type zinc finger
6 CSNK1A1suppressor100Pkinase (PF00069, IPR000719): Protein kinase domain
7 SEToncoprotein200NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
8 SRPK2oncoprotein200DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)

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