Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CHP1, R3HCC1L (from a repository: Mon Oct 14 16:06:54 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)23
The number (and %) of the onco-proteins3 (13.04 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)40 (15.81 %)
The number (and %) of affected PPIs22 (55.00 %)
The number of possible different fusions2
PPI diameter4
PPI radius2
The average degree of PPI3.130
Assortativity coefficient-0.5265
The network average Clustering coefficient0.239
The number (and %) of a zero Clustering coefficients12 (52.17 %)
The number (and %) of a zero Betweenness Centrality11 (47.83 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CHP1,R3HCC1L All fusions
Proteins found in more fusions PABPC1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CHP1parental protein120.076229.167EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
2 R3HCC1Lparental protein100.044181.667NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
UPF0561 (PF10573, IPR018888): Uncharacterised protein family UPF0561
3 CCDC103interactor100RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3
Dynein_attach_N (PF15867, IPR031733): Dynein attachment factor N-terminus
4 CEP19interactor100CEP19 (PF14933, IPR029412): CEP19-like protein
5 ELAVL1oncoprotein70.33340.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
6 LRRIQ3interactor1002CSK_N (PF08521, IPR013727): Two-component sensor kinase N-terminal
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
LRR_9 (PF14580): Leucine-rich repeat
DUF4883 (PF16224, IPR032619): DOmain of unknown function (DUF4883)
7 MAGOHinteractor30.6675.000Mago_nashi (PF02792, IPR004023): Mago nashi protein
8 MKS1interactor3018.667B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein
9 MOV10interactor2065.000AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
10 NXF1interactor50.33335.000NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
11 PABPC1oncoprotein50.33335.333RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
12 POC1Ainteractor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
13 PRSS23interactor21.0000Trypsin (PF00089, IPR001254, SM00020): Trypsin
14 RBM8Ainteractor50.5007.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
15 SARSinteractor203.333NOD (PF06816, IPR010660): NOTCH protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
16 SHMT2interactor207.000SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
17 SLC9A1interactor100DUF1427 (PF07235, IPR009872): Protein of unknown function (DUF1427)
LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
18 SLC9A2oncoprotein100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
19 SLC9A3interactor100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
20 SLC9A4interactor100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
21 SLC9A5interactor21.0000Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
22 TMEM216interactor21.0000Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
23 XPO1interactor60.20045.833CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

B a c k    t o    T o p ⇑