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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)112
The number (and %) of the onco-proteins35 (31.25 %)
The number (and %) of the tumor suppressors6 (5.36 %)
Total number of binary PPIs (saturation %)639 (10.28 %)
The number (and %) of affected PPIs113 (17.68 %)
The number of possible different fusions16
PPI diameter4
PPI radius2
The average degree of PPI10.821
Assortativity coefficient-0.2447
The network average Clustering coefficient0.481
The number (and %) of a zero Clustering coefficients13 (11.61 %)
The number (and %) of a zero Betweenness Centrality17 (15.18 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: WDR82,PROSC All fusions
Proteins found in more fusions GRK5 (see 4 fusions); CUL4A (see 4 fusions); VCP (see 4 fusions); ASH2L/DPY30 (see 1 fusions); PPP1R10 (see 1 fusions); HUWE1 (see 2 fusions); NDUFS3 (see 1 fusions); MCM2 (see 1 fusions); NAGK (see 1 fusions); POLR2A (see 2 fusions); DDX17 (see 3 fusions); EP300 (see 1 fusions); HCFC1 (see 2 fusions); RPA1 (see 1 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 WDR82parental protein550.1522952.326MinC_C (PF03775, IPR005526): Septum formation inhibitor MinC, C-terminal domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
2 PROSCparental protein580.0973591.706Ala_racemase_N (PF01168, IPR001608): Alanine racemase, N-terminal domain
3 ADI1interactor100ARD (PF03079, IPR004313): ARD/ARD' family
4 AHSA1interactor120.34866.225Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
5 ANAPC15interactor2011.269Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
ANAPC15 (PF15243, IPR026182): Anaphase-promoting complex subunit 15
6 ARFIP1interactor21.0000Arfaptin (PF06456, IPR010504, SM01015): Arfaptin-like domain
7 ASB6interactor50.60016.707Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
8 ASH2Lprotein found in more fusions180.51560.722SPRY (PF00622, IPR003877, SM00449): SPRY domain
PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
9 ASNSoncoprotein160.56757.029Asn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
10 ATIConcoprotein130.56434.033AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
11 BIRC2oncoprotein40.6673.731BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
12 BIRC3oncoprotein40.6673.731BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
13 C17orf49interactor21.0000Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
14 CAPN2interactor190.409108.584Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
15 CAPNS1interactor130.67934.235EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
16 CARSoncoprotein50.40039.094tRNA-synt_1e (PF01406, IPR024909): tRNA synthetases class I (C) catalytic domain
17 CCT3interactor110.65572.644Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
18 CCT5interactor110.74510.811Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
19 CCT7interactor90.9171.841Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
20 CDK5R1oncoprotein100CDK5_activator (PF03261, IPR004944): Cyclin-dependent kinase 5 activator protein
21 CHORDC1interactor90.32186.598CHORD (PF04968, IPR007051): CHORD
CS (PF04969, IPR007052): CS domain
22 CUL4Aprotein found in more fusions110.55615.817Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
23 CUL4Boncoprotein140.418152.509Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
24 CXXC1interactor120.68220.078ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLATZ (PF04640, IPR006734): PLATZ transcription factor
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347)
zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain
25 DDX17protein found in more fusions120.50971.483CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
26 DPY30protein found in more fusions130.56165.292Dpy-30 (PF05186, IPR007858): Dpy-30 motif
27 EIF4Eoncoprotein30.6672.013IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
28 ENSAinteractor100Endosulfine (PF04667, IPR006760): cAMP-regulated phosphoprotein/endosulfine conserved region
29 EP300oncoprotein140.372167.015Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
30 FCGR2Ainteractor100DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827)
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
31 GLOD4interactor40.6673.333Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
32 GMPPBinteractor21.0000Hexapep (PF00132, IPR001451): Bacterial transferase hexapeptide (six repeats)
NTP_transferase (PF00483, IPR005835): Nucleotidyl transferase
33 GOT1interactor60.26782.092Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
34 GRK2interactor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
35 GRK5protein found in more fusions60.5009.728Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
36 GSRinteractor50.8332.013Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
37 GTF3C4interactor70.38171.561TFIIIC_delta (PF12657, IPR024761): Transcription factor IIIC subunit delta N-term
zf-TFIIIC (PF12660, IPR024764): Putative zinc-finger of transcription factor IIIC complex
38 HCFC1protein found in more fusions160.45774.056fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
39 HEXBinteractor60.7002.875Glyco_hydro_20 (PF00728, IPR015883): Glycosyl hydrolase family 20, catalytic domain
Glyco_hydro_20b (PF02838, IPR015882): Glycosyl hydrolase family 20, domain 2
Glycohydro_20b2 (PF14845, IPR029019): beta-acetyl hexosaminidase like
40 HK1interactor80.60718.530Hexokinase_1 (PF00349, IPR022672): Hexokinase
Hexokinase_2 (PF03727, IPR022673): Hexokinase
41 HNRNPA1interactor220.371287.324RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
42 HNRNPA3oncoprotein120.62153.887IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
43 HSPA4interactor150.48667.581Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
44 HSPA8oncoprotein210.390197.411HSP70 (PF00012, IPR013126): Hsp70 protein
45 HUWE1oncoprotein260.303289.325BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
46 ISOC1interactor150.64838.814Isochorismatase (PF00857, IPR000868): Isochorismatase family
Glyco_trans_4_4 (PF13579, IPR028098): Glycosyl transferase 4-like domain
47 KDM6Asuppressor80.8572.279JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
48 KMT2Boncoprotein51.0000FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
GRP (PF07172, IPR010800): Glycine rich protein family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
49 KMT2Csuppressor70.9520.515AT_hook (PF02178, IPR017956, SM00384): AT hook motif
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
SLC12 (PF03522, IPR018491): Solute carrier family 12
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
50 KMT2Doncoprotein80.7143.583DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Mnd1 (PF03962, IPR005647): Mnd1 family
PHD (PF00628, IPR019787, SM00249): PHD-finger
Pox_F17 (PF04767, IPR006854): DNA-binding 11 kDa phosphoprotein
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
SET (PF00856, IPR001214, SM00317): SET domain
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
Fer4_4 (PF12800, IPR001450): 4Fe-4S binding domain
DUF4163 (PF13739, IPR025303): Domain of unknown function (DUF4163)
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
Hydin_ADK (PF17213): Hydin Adenylate kinase-like domain
51 MCM2oncoprotein290.299430.433AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
52 MCTS1interactor130.53837.660DUF1947 (PF09183, IPR015266): Domain of unknown function (DUF1947)
PUA (PF01472, IPR002478, SM00359): PUA domain
53 MYEF2interactor30.3334.762RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
54 MYO1Einteractor140.45189.324IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
55 NAE1interactor110.54530.674ThiF (PF00899, IPR000594): ThiF family
56 NAGKprotein found in more fusions50.50092.251BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family
57 NDUFS3protein found in more fusions40.3335.390Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
58 NME4interactor4046.148NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
59 NTRK1oncoprotein470.1571641.760I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
60 OGFOD1interactor150.65721.643Ofd1_CTDD (PF10637, IPR019601): Oxoglutarate and iron-dependent oxygenase degradation C-term
2OG-FeII_Oxy_4 (PF13661): 2OG-Fe(II) oxygenase superfamily
61 OSGEPinteractor200Peptidase_M22 (PF00814, IPR000905): Glycoprotease family
62 OXNAD1interactor100NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
63 PAFAH1B2oncoprotein80.42942.263Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family
64 PAPOLAinteractor60.33361.626PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain
PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
65 PARD6Binteractor40.16716.759PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
66 PAXIP1interactor140.440108.730BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
67 PCK2interactor3016.444PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
68 PDIA4interactor190.50979.133Calsequestrin (PF01216, IPR001393): Calsequestrin
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
FAM176 (PF14851): FAM176 family
69 PHGDHinteractor80.46475.2452-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
70 PHPT1interactor100Ocnus (PF05005, IPR007702): Janus/Ocnus family (Ocnus)
71 POLR2Aprotein found in more fusions120.38288.614RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
72 POLR2Binteractor50.8000.855RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
73 PPIL3interactor31.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
74 PPP1CAsuppressor200.316274.465Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
75 PPP1CBinteractor150.333148.083Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
76 PPP1CConcoprotein150.44871.078Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
77 PPP1R10protein found in more fusions130.59123.709Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
78 PPP1R2interactor120.333164.551IPP-2 (PF04979, IPR007062): Protein phosphatase inhibitor 2 (IPP-2)
79 PPP1R3Ainteractor60.80013.729CBM_21 (PF03370, IPR005036): Carbohydrate/starch-binding module (family 21)
80 PRCPinteractor50.9000.747Peptidase_S28 (PF05577, IPR008758): Serine carboxypeptidase S28
81 PTMAoncoprotein140.63771.399Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
82 PYDC1interactor100PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
83 RAE1interactor40.33327.993Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
84 RBBP5oncoprotein180.52245.845WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
85 RBM10interactor90.35730.454G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
zf-C2H2_4 (PF13894): C2H2-type zinc finger
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
FAM176 (PF14851): FAM176 family
86 RPA1suppressor210.379356.874Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
87 RPA2oncoprotein170.43472.726RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
88 RPA3interactor160.45757.692Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
89 SBDSoncoprotein40.33343.485SBDS (PF01172, IPR019783): Shwachman-Bodian-Diamond syndrome (SBDS) protein
SBDS_C (PF09377, IPR018978): SBDS protein C-terminal domain
90 SETD1Ainteractor110.7457.107E7 (PF00527, IPR000148): E7 protein, Early protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SET (PF00856, IPR001214, SM00317): SET domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N
DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632)
DUF4667 (PF15700, IPR031426): Domain of unknown function (DUF4667)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
91 SETD1Binteractor80.8212.019Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SET (PF00856, IPR001214, SM00317): SET domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
4HBT_3 (PF13622): Thioesterase-like superfamily
SOBP (PF15279, IPR026092): Sine oculis-binding protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
92 SLC25A32interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
93 SMSinteractor40.5003.954Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase
94 SOX2oncoprotein60.30060.491HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
95 STK26interactor160.72414.798DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
96 SUMO3interactor100Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
97 TATDN1interactor100.46719.463TatD_DNase (PF01026, IPR001130): TatD related DNase
98 TBCBinteractor130.71831.708CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain
99 TCP1interactor100.8443.469Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
100 TOX4interactor90.8212.641Extensin_2 (PF04554, IPR006706): Extensin-like region
FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
YABBY (PF04690, IPR006780): YABBY protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
101 TP53suppressor290.257423.364DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
102 TUFMinteractor160.350182.689GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
103 TWF2interactor120.62121.908Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
104 UBXN1interactor180.279280.793Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UBX (PF00789, IPR001012, SM00166): UBX domain
105 UCHL1suppressor40.8330.507Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
106 ULK3interactor21.0000MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
Pkinase (PF00069, IPR000719): Protein kinase domain
107 USP37interactor100.306108.319UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37
108 VCPprotein found in more fusions190.451130.698AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
109 WDR5interactor200.426196.368WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
110 XPO1interactor220.251417.575CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
111 YARSinteractor50.50023.116tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y)
tRNA_bind (PF01588, IPR002547): Putative tRNA binding domain
112 YWHAEoncoprotein260.354348.06614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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