1 |
MED1 | parental protein | 94 | 0.230 | 5358.887 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
2 |
CEP250 | parental protein | 233 | 0.087 | 34868.828 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
3 |
ABR | oncoprotein | 6 | 0.400 | 5.916 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PH_10 (PF15411): Pleckstrin homology domain Tox-PL-2 (PF15643, IPR028910): Papain fold toxin 2 |
4 |
ACTB | oncoprotein | 23 | 0.351 | 98.437 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ADAMTS1 | oncoprotein | 1 | 0 | 0 | ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1 Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain |
6 |
AGO2 | interactor | 13 | 0.333 | 100.492 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
7 |
AKAP12 | suppressor | 2 | 0 | 0.782 | OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain ROS_MUCR (PF05443, IPR008807): ROS/MUCR transcriptional regulator protein RII_binding_1 (PF10522, IPR018459): RII binding domain WSK (PF03832, IPR001573): WSK motif |
8 |
ALYREF | interactor | 18 | 0.471 | 89.434 | FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
9 |
AMER1 | suppressor | 3 | 0.333 | 2.792 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region WTX (PF09422, IPR019003): WTX protein RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 |
10 |
AMOT | oncoprotein | 10 | 0.167 | 41.003 | FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162) Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
11 |
ANKIB1 | interactor | 1 | 0 | 0 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
12 |
APC | suppressor | 9 | 0.250 | 51.833 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
13 |
APP | protein found in more fusions | 53 | 0.162 | 2432.661 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
14 |
AR | oncoprotein | 21 | 0.237 | 180.174 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
15 |
ARHGEF2 | oncoprotein | 9 | 0.444 | 8.977 | IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
16 |
ATM | suppressor | 13 | 0.394 | 44.063 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
17 |
BAG3 | oncoprotein | 21 | 0.168 | 124.616 | BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain |
18 |
BORCS6 | interactor | 3 | 0.667 | 1.167 | DUF2365 (PF10157, IPR019314): Uncharacterized conserved protein (DUF2365) |
19 |
BRD4 | oncoprotein | 10 | 0.422 | 33.140 | Caldesmon (PF02029, IPR006018): Caldesmon Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Stm1_N (PF09598, IPR019084): Stm1 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
20 |
CALU | interactor | 5 | 0.400 | 2.368 | EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
21 |
CCDC8 | interactor | 79 | 0.225 | 1511.922 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
22 |
CCDC87 | interactor | 3 | 0.667 | 3.481 | MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) |
23 |
CCDC88A | protein found in more fusions | 6 | 0.400 | 4.606 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) HOOK (PF05622, IPR008636): HOOK protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL (PF10241, IPR019371): Uncharacterized conserved protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
24 |
CCNC | suppressor | 33 | 0.790 | 109.642 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain |
25 |
CDK19 | interactor | 31 | 0.837 | 55.199 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase (PF00069, IPR000719): Protein kinase domain |
26 |
CDK8 | interactor | 49 | 0.533 | 577.257 | Pkinase (PF00069, IPR000719): Protein kinase domain |
27 |
CDK9 | protein found in more fusions | 35 | 0.191 | 763.160 | Pkinase (PF00069, IPR000719): Protein kinase domain |
28 |
CEP170 | interactor | 13 | 0.359 | 102.625 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF4254 (PF14063, IPR025350): Protein of unknown function (DUF4254) CEP170_C (PF15308, IPR029300): CEP170 C-terminus |
29 |
CEP350 | interactor | 11 | 0.345 | 113.337 | CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region MAS20 (PF02064, IPR002056): MAS20 protein import receptor Mucin (PF01456, IPR000458): Mucin-like glycoprotein Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment Complex1_LYR_2 (PF13233): Complex1_LYR-like AAA_23 (PF13476): AAA domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
30 |
CEP78 | interactor | 3 | 0.667 | 0.061 | Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DUF3122 (PF11320, IPR021469): Protein of unknown function (DUF3122) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
31 |
CLINT1 | protein found in more fusions | 9 | 0.429 | 19.121 | ENTH (PF01417, IPR001026, SM00273): ENTH domain |
32 |
CLSPN | interactor | 3 | 0.333 | 4.792 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) NinG (PF05766, IPR008713): Bacteriophage Lambda NinG protein Presenilin (PF01080, IPR001108): Presenilin PTS_IIB (PF02302, IPR003501): PTS system, Lactose/Cellobiose specific IIB subunit XAP5 (PF04921, IPR007005): XAP5, circadian clock regulator Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
33 |
COG3 | interactor | 3 | 0.333 | 1.410 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus OpuAC (PF04069, IPR007210): Substrate binding domain of ABC-type glycine betaine transport system Sec34 (PF04136, IPR007265): Sec34-like family Thioredoxin_6 (PF13848): Thioredoxin-like domain |
34 |
CPNE7 | suppressor | 2 | 0 | 0.782 | C2 (PF00168, IPR000008, SM00239): C2 domain Copine (PF07002, IPR010734): Copine Halo_GVPC (PF05465, IPR008639): Halobacterial gas vesicle protein C (GVPC) repeat |
35 |
CRTC2 | oncoprotein | 5 | 0.400 | 4.423 | TORC_N (PF12884, IPR024783): Transducer of regulated CREB activity, N terminus TORC_M (PF12885, IPR024784): Transducer of regulated CREB activity middle domain TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus |
36 |
CTDP1 | interactor | 19 | 0.725 | 22.651 | Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme FCP1_C (PF09309, IPR015388): FCP1, C-terminal NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A PTCB-BRCT (PF12738, IPR001357): twin BRCT domain HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion |
37 |
CUL7 | protein found in more fusions | 98 | 0.240 | 2265.381 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
38 |
DAP3 | interactor | 19 | 0.431 | 136.975 | DAP3 (PF10236, IPR019368): Mitochondrial ribosomal death-associated protein 3 |
39 |
DCAF1 | protein found in more fusions | 13 | 0.500 | 34.204 | DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
40 |
DDB1 | protein found in more fusions | 23 | 0.251 | 274.255 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
41 |
DDX17 | protein found in more fusions | 22 | 0.381 | 79.926 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
42 |
DDX21 | interactor | 22 | 0.584 | 34.283 | CRT10 (PF08728, IPR014839): CRT10 DEAD (PF00270, IPR011545): DEAD/DEAH box helicase GUCT (PF08152, IPR012562): GUCT (NUC152) domain Sulfatase (PF00884, IPR000917): Sulfatase MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
43 |
DDX24 | interactor | 26 | 0.563 | 45.904 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Sec62 (PF03839, IPR004728): Translocation protein Sec62 Tti2 (PF10521, IPR018870): Tti2 family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
44 |
DDX41 | interactor | 5 | 0.500 | 1.476 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase zf-CCHC (PF00098, IPR001878): Zinc knuckle Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
45 |
DDX5 | oncoprotein | 33 | 0.363 | 258.721 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
46 |
DGCR14 | interactor | 2 | 0 | 0.782 | Es2 (PF09751, IPR019148): Nuclear protein Es2 |
47 |
DHX15 | interactor | 23 | 0.379 | 76.112 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
48 |
DHX9 | oncoprotein | 37 | 0.374 | 176.388 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
49 |
DOCK7 | interactor | 10 | 0.267 | 131.881 | DHR-2 (PF06920, IPR010703): Dock homology region 2 DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398) DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins DOCK_N (PF16172, IPR032376): DOCK N-terminus |
50 |
EEF1A1 | suppressor | 60 | 0.452 | 390.020 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
51 |
EIF4EBP3 | interactor | 1 | 0 | 0 | eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) |
52 |
EIF4ENIF1 | interactor | 6 | 0.333 | 8.579 | EIF4E-T (PF10477, IPR018862): Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718) |
53 |
ELAVL1 | oncoprotein | 60 | 0.107 | 2436.153 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
54 |
EMC2 | interactor | 8 | 0.536 | 22.839 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_19 (PF14559): Tetratricopeptide repeat Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation |
55 |
ENO1 | oncoprotein | 18 | 0.288 | 137.811 | Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain |
56 |
EPAS1 | suppressor | 26 | 0.610 | 244.919 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
57 |
EPPK1 | interactor | 4 | 0.500 | 2.507 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HupF_HypC (PF01455, IPR001109): HupF/HypC family Plectin (PF00681, IPR001101, SM00250): Plectin repeat RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal |
58 |
ESR1 | suppressor | 108 | 0.220 | 5081.843 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
59 |
ESR2 | suppressor | 34 | 0.333 | 474.607 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
60 |
EXOSC6 | protein found in more fusions | 6 | 0.300 | 8.261 | RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 |
61 |
EZH2 | suppressor | 32 | 0.116 | 413.996 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
62 |
F7 | interactor | 1 | 0 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain Gla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Trypsin (PF00089, IPR001254, SM00020): Trypsin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
63 |
FAM120A | interactor | 8 | 0.321 | 14.019 | TPR_15 (PF13429): Tetratricopeptide repeat |
64 |
FBL | interactor | 44 | 0.474 | 478.677 | Fibrillarin (PF01269, IPR000692): Fibrillarin |
65 |
FBXW7 | suppressor | 43 | 0.422 | 753.450 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
66 |
FTL | protein found in more fusions | 3 | 1.000 | 0 | Ferritin (PF00210, IPR008331): Ferritin-like domain |
67 |
GABPA | protein found in more fusions | 2 | 0 | 0.549 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain GABP-alpha (PF11620, IPR024668): GA-binding protein alpha chain Wap1 (PF16997, IPR031550): Wap1 domain |
68 |
GALNT18 | interactor | 1 | 0 | 0 | Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2 Ricin_B_lectin (PF00652, IPR000772, SM00458): Ricin-type beta-trefoil lectin domain |
69 |
GATA1 | oncoprotein | 4 | 0.500 | 4.133 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
70 |
GATA2 | oncoprotein | 6 | 0.267 | 35.475 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
71 |
GIGYF1 | interactor | 4 | 0.333 | 3.093 | GYF (PF02213, IPR003169, SM00444): GYF domain RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component) PRTase_3 (PF15610, IPR028944): PRTase ComF-like VIR_N (PF15912, IPR031801): Virilizer, N-terminal |
72 |
GIGYF2 | interactor | 13 | 0.462 | 27.950 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
73 |
GJB5 | interactor | 1 | 0 | 0 | Connexin (PF00029, IPR013092, SM00037): Connexin |
74 |
GOLGA3 | interactor | 4 | 0.333 | 2.003 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 G-gamma (PF00631, IPR015898, SM00224): GGL domain SOGA (PF11365, IPR027881): Protein SOGA TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation |
75 |
GRPR | oncoprotein | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
76 |
GTF3C3 | interactor | 9 | 0.417 | 58.360 | BUD22 (PF09073, IPR015158): BUD22 PGA2 (PF07543, IPR011431): Protein trafficking PGA2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369) ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat TPR_20 (PF14561): Tetratricopeptide repeat |
77 |
GTF3C5 | interactor | 5 | 0.700 | 1.363 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein Tau95 (PF09734, IPR019136): RNA polymerase III transcription factor (TF)IIIC subunit |
78 |
H1FX | interactor | 7 | 0.619 | 3.171 | IGPS (PF00218, IPR013798): Indole-3-glycerol phosphate synthase |
79 |
HAUS1 | interactor | 18 | 0.279 | 180.533 | THP2 (PF09432, IPR018557): Tho complex subunit THP2 XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496) |
80 |
HAUS5 | interactor | 7 | 0.476 | 15.835 | HAUS5 (PF14817, IPR029131): HAUS augmin-like complex subunit 5 |
81 |
HAX1 | interactor | 7 | 0.571 | 8.984 | Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein |
82 |
HBA1 | interactor | 3 | 0.667 | 0.998 | Globin (PF00042, IPR000971): Globin |
83 |
HBB | interactor | 4 | 0.333 | 35.779 | Globin (PF00042, IPR000971): Globin |
84 |
HDAC5 | protein found in more fusions | 55 | 0.254 | 901.576 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
85 |
HERC2 | interactor | 15 | 0.275 | 179.199 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIB_HERC2 (PF06701, IPR010606): Mib_herc2 RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
86 |
HIST1H1C | oncoprotein | 9 | 0.444 | 19.966 | Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349) |
87 |
HIST1H4H | interactor | 3 | 0.667 | 0.057 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
88 |
HNF4A | suppressor | 20 | 0.509 | 72.766 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
89 |
HNRNPC | protein found in more fusions | 21 | 0.453 | 113.870 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
90 |
HNRNPF | interactor | 23 | 0.447 | 118.023 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
91 |
HNRNPH1 | oncoprotein | 21 | 0.519 | 46.050 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
92 |
HNRNPM | interactor | 60 | 0.376 | 620.687 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
93 |
HNRNPR | interactor | 33 | 0.366 | 216.285 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
94 |
HNRNPU | protein found in more fusions | 95 | 0.358 | 1582.123 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
95 |
HOOK2 | interactor | 2 | 0 | 0 | HOOK (PF05622, IPR008636): HOOK protein |
96 |
HP1BP3 | interactor | 17 | 0.456 | 53.209 | RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SDA1 (PF05285, IPR007949): SDA1 YL1 (PF05764, IPR008895): YL1 nuclear protein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family |
97 |
HSP90AA1 | oncoprotein | 58 | 0.243 | 1397.435 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
98 |
HSP90AB1 | oncoprotein | 41 | 0.456 | 149.185 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
99 |
HSPA1A | interactor | 23 | 0.419 | 107.836 | HSP70 (PF00012, IPR013126): Hsp70 protein |
100 |
HSPA1L | interactor | 11 | 0.527 | 20.421 | HSP70 (PF00012, IPR013126): Hsp70 protein |
101 |
HSPA2 | interactor | 12 | 0.500 | 28.640 | HSP70 (PF00012, IPR013126): Hsp70 protein |
102 |
HSPA5 | oncoprotein | 42 | 0.280 | 420.668 | HSP70 (PF00012, IPR013126): Hsp70 protein |
103 |
HSPA7 | interactor | 3 | 1.000 | 0 | NA |
104 |
HSPA8 | oncoprotein | 34 | 0.381 | 179.320 | HSP70 (PF00012, IPR013126): Hsp70 protein |
105 |
HSPA9 | oncoprotein | 19 | 0.415 | 44.646 | HSP70 (PF00012, IPR013126): Hsp70 protein |
106 |
HUWE1 | oncoprotein | 68 | 0.330 | 1157.913 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
107 |
IGF2BP1 | oncoprotein | 12 | 0.409 | 21.411 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain |
108 |
IRS4 | interactor | 17 | 0.390 | 73.040 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence PH_11 (PF15413): Pleckstrin homology domain |
109 |
KAT2A | interactor | 19 | 0.386 | 117.487 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family |
110 |
KAT2B | protein found in more fusions | 20 | 0.333 | 228.840 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
111 |
KIF1A | interactor | 6 | 0.400 | 28.694 | FHA (PF00498, IPR000253, SM00240): FHA domain IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain KIF1B (PF12423, IPR022140): Kinesin protein 1B Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF3694 (PF12473, IPR022164): Kinesin protein Kinesin_assoc (PF16183, IPR032405): Kinesin-associated |
112 |
LAS1L | interactor | 4 | 0.667 | 0.963 | BUD22 (PF09073, IPR015158): BUD22 eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus Las1 (PF04031, IPR007174): Las1-like NOA36 (PF06524, IPR010531): NOA36 protein CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus |
113 |
LGALS3BP | oncoprotein | 28 | 0.385 | 93.619 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain |
114 |
LRCH2 | interactor | 2 | 1.000 | 0 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain |
115 |
LRPPRC | interactor | 15 | 0.248 | 93.361 | DED (PF01335, IPR001875, SM00031): Death effector domain MA3 (PF02847, IPR003891, SM00544): MA3 domain PPR (PF01535, IPR002885): PPR repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain TPR_19 (PF14559): Tetratricopeptide repeat PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR |
116 |
LZTFL1 | interactor | 3 | 0 | 1.108 | Leu_zip (PF15294): Leucine zipper |
117 |
LZTS2 | suppressor | 8 | 0.250 | 186.273 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127) Fez1 (PF06818): Fez1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250) |
118 |
MAGED1 | protein found in more fusions | 11 | 0.267 | 32.965 | MAGE (PF01454, IPR002190): MAGE family |
119 |
MAGED2 | interactor | 21 | 0.395 | 206.774 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 MAGE (PF01454, IPR002190): MAGE family SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
120 |
MAP7D3 | interactor | 9 | 0.528 | 22.530 | DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family Sec62 (PF03839, IPR004728): Translocation protein Sec62 Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa) ARGLU (PF15346): Arginine and glutamate-rich 1 |
121 |
MATR3 | protein found in more fusions | 26 | 0.383 | 125.105 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
122 |
MBD3 | interactor | 8 | 0.333 | 29.135 | DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain |
123 |
MCM7 | protein found in more fusions | 16 | 0.343 | 82.065 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
124 |
MDM2 | oncoprotein | 48 | 0.241 | 695.773 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
125 |
MED10 | interactor | 43 | 0.658 | 107.483 | Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex |
126 |
MED11 | interactor | 29 | 0.845 | 31.846 | Med11 (PF10280, IPR019404): Mediator complex protein |
127 |
MED12 | oncoprotein | 54 | 0.477 | 631.531 | Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12 Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877) Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
128 |
MED13 | oncoprotein | 39 | 0.667 | 81.245 | Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal |
129 |
MED13L | protein found in more fusions | 18 | 0.974 | 0.578 | Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal |
130 |
MED14 | interactor | 52 | 0.472 | 506.664 | Med14 (PF08638, IPR013947): Mediator complex subunit MED14 |
131 |
MED15 | interactor | 40 | 0.645 | 74.284 | Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal |
132 |
MED16 | interactor | 53 | 0.480 | 544.490 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Med16 (PF11635, IPR021665): Mediator complex subunit 16 |
133 |
MED17 | oncoprotein | 56 | 0.461 | 748.271 | Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex |
134 |
MED18 | interactor | 32 | 0.867 | 10.009 | Med18 (PF09637, IPR019095): Med18 protein |
135 |
MED19 | interactor | 39 | 0.733 | 74.542 | Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 |
136 |
MED20 | interactor | 41 | 0.605 | 413.671 | Med20 (PF08612, IPR013921): TATA-binding related factor (TRF) of subunit 20 of Mediator complex |
137 |
MED21 | protein found in more fusions | 40 | 0.619 | 239.412 | Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex |
138 |
MED22 | interactor | 27 | 0.812 | 91.043 | Med22 (PF06179, IPR009332): Surfeit locus protein 5 subunit 22 of Mediator complex |
139 |
MED23 | interactor | 57 | 0.444 | 994.088 | Med23 (PF11573, IPR021629): Mediator complex subunit 23 |
140 |
MED24 | interactor | 53 | 0.478 | 388.890 | Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal |
141 |
MED25 | interactor | 35 | 0.581 | 116.125 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A |
142 |
MED26 | interactor | 43 | 0.650 | 107.161 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain |
143 |
MED27 | interactor | 36 | 0.779 | 51.528 | Med27 (PF11571, IPR021627): Mediator complex subunit 27 |
144 |
MED28 | interactor | 44 | 0.626 | 292.789 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28 |
145 |
MED29 | interactor | 46 | 0.609 | 247.649 | Med29 (PF11568, IPR021018): Mediator complex subunit 29 |
146 |
MED30 | interactor | 35 | 0.766 | 49.228 | Med30 (PF11315, IPR021019): Mediator complex subunit 30 |
147 |
MED31 | interactor | 20 | 0.753 | 29.709 | Med31 (PF05669, IPR008831): SOH1 |
148 |
MED4 | interactor | 67 | 0.313 | 2382.558 | Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4 |
149 |
MED6 | interactor | 42 | 0.653 | 131.527 | Med6 (PF04934, IPR007018): MED6 mediator sub complex component Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase |
150 |
MED7 | interactor | 40 | 0.662 | 152.279 | Med7 (PF05983, IPR009244): MED7 protein DotU (PF09850, IPR017732): Type VI secretion system protein DotU |
151 |
MED8 | interactor | 39 | 0.663 | 299.841 | Med8 (PF10232, IPR019364): Mediator of RNA polymerase II transcription complex subunit 8 |
152 |
MED9 | interactor | 39 | 0.706 | 107.459 | Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9 |
153 |
MIB1 | protein found in more fusions | 10 | 0.417 | 35.453 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat MIB_HERC2 (PF06701, IPR010606): Mib_herc2 ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
154 |
MOGS | interactor | 11 | 0.291 | 128.869 | Glyco_hydro_63 (PF03200, IPR004888): Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N (PF16923, IPR031631): Glycosyl hydrolase family 63 N-terminal domain |
155 |
MOV10 | interactor | 50 | 0.160 | 1263.276 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
156 |
MRPS14 | interactor | 9 | 0.833 | 2.315 | Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e |
157 |
MRPS18B | interactor | 12 | 0.485 | 27.223 | Ribosomal_S18 (PF01084, IPR001648): Ribosomal protein S18 HTH_21 (PF13276, IPR025948): HTH-like domain zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2 |
158 |
MRPS2 | interactor | 15 | 0.571 | 49.943 | Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 |
159 |
MRPS22 | interactor | 15 | 0.562 | 36.812 | MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22 |
160 |
MRPS23 | interactor | 10 | 0.778 | 6.088 | MRP-S23 (PF10484, IPR023611): Mitochondrial ribosomal protein S23 |
161 |
MRPS34 | interactor | 8 | 0.714 | 3.416 | MRP-S34 (PF16053, IPR032053): Mitochondrial 28S ribosomal protein S34 |
162 |
MRPS35 | interactor | 11 | 0.709 | 8.167 | MRP-S28 (PF10213, IPR019349): Mitochondrial ribosomal subunit protein |
163 |
MRPS9 | interactor | 20 | 0.516 | 98.750 | Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16 |
164 |
MTMR1 | interactor | 1 | 0 | 0 | GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain 3-PAP (PF12578, IPR022587): Myotubularin-associated protein Myb_CC_LHEQLE (PF14379, IPR025756): MYB-CC type transfactor, LHEQLE motif |
165 |
MYC | oncoprotein | 56 | 0.166 | 1406.824 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
166 |
MYH9 | suppressor | 18 | 0.386 | 66.748 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
167 |
N4BP2 | interactor | 2 | 0 | 0 | CUE (PF02845, IPR003892, SM00546): CUE domain DUF1771 (PF08590, IPR013899, SM01162): Domain of unknown function (DUF1771) RyR (PF02026, IPR003032): RyR domain Smr (PF01713, IPR002625, SM00463): Smr domain AAA_22 (PF13401, IPR003593): AAA domain AAA_33 (PF13671): AAA domain |
168 |
NAP1L4 | protein found in more fusions | 12 | 0.255 | 23.910 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
169 |
NCOA6 | oncoprotein | 20 | 0.275 | 142.122 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
170 |
NDE1 | protein found in more fusions | 11 | 0.200 | 169.657 | NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
171 |
NEK2 | interactor | 3 | 0 | 1.493 | Pkinase (PF00069, IPR000719): Protein kinase domain |
172 |
NEURL4 | interactor | 6 | 0.733 | 6.677 | Neuralized (PF07177, IPR006573, SM00588): Neuralized |
173 |
NINL | interactor | 19 | 0.181 | 153.357 | PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat TBCA (PF02970, IPR004226): Tubulin binding cofactor A DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389) Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein FAM184 (PF15665): Family with sequence similarity 184, A and B TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
174 |
NOC4L | interactor | 2 | 1.000 | 0 | CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family |
175 |
NOP2 | interactor | 37 | 0.605 | 139.099 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F P120R (PF08062, IPR012586): P120R (NUC006) repeat Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477) FAM176 (PF14851): FAM176 family Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
176 |
NR1H2 | oncoprotein | 6 | 0.600 | 6.275 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
177 |
NR1I3 | interactor | 16 | 0.417 | 120.518 | PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
178 |
NR3C1 | protein found in more fusions | 19 | 0.268 | 232.019 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
179 |
NTRK1 | oncoprotein | 133 | 0.122 | 7403.159 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
180 |
NUP43 | interactor | 3 | 1.000 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
181 |
NUP62 | interactor | 7 | 0.333 | 10.277 | Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region |
182 |
NXF1 | interactor | 50 | 0.099 | 989.391 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
183 |
PABPC1 | oncoprotein | 52 | 0.437 | 424.823 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
184 |
PARD3B | interactor | 1 | 0 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) |
185 |
PARP1 | suppressor | 41 | 0.235 | 685.329 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
186 |
PCBP2 | protein found in more fusions | 15 | 0.407 | 80.694 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
187 |
PCM1 | oncoprotein | 19 | 0.345 | 147.263 | FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus FUSC (PF04632, IPR006726): Fusaric acid resistance protein family IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family AAA_23 (PF13476): AAA domain zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829) |
188 |
PHLDB2 | interactor | 4 | 0.667 | 1.608 | DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family PH (PF00169, IPR001849, SM00233): PH domain Synaptobrevin (PF00957, IPR001388): Synaptobrevin DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
189 |
PIAS1 | suppressor | 10 | 0.361 | 262.136 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544 |
190 |
PIN1 | suppressor | 22 | 0.255 | 198.271 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
191 |
PKP2 | interactor | 6 | 0.467 | 3.978 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383) |
192 |
PLEKHA5 | protein found in more fusions | 6 | 0.400 | 5.259 | PH (PF00169, IPR001849, SM00233): PH domain WW (PF00397, IPR001202, SM00456): WW domain MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1 |
193 |
PLK4 | interactor | 9 | 0.286 | 13.821 | ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520) |
194 |
POLL | interactor | 4 | 0 | 6.326 | HHH (PF00633, IPR000445): Helix-hairpin-helix motif DNA_pol_lambd_f (PF10391, IPR018944): Fingers domain of DNA polymerase lambda HHH_5 (PF14520): Helix-hairpin-helix domain HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb DNA_pol_B_palm (PF14792, IPR028207): DNA polymerase beta palm BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
195 |
POLR2A | protein found in more fusions | 52 | 0.228 | 1392.507 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
196 |
POLR2E | protein found in more fusions | 20 | 0.456 | 149.501 | RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain |
197 |
POLR2F | interactor | 15 | 0.705 | 29.948 | RNA_pol_Rpb6 (PF01192, IPR006110): RNA polymerase Rpb6 |
198 |
POLR2G | interactor | 24 | 0.696 | 58.578 | SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain |
199 |
POU1F1 | interactor | 6 | 0.467 | 5.358 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2 |
200 |
PPARG | suppressor | 19 | 0.261 | 166.718 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
201 |
PPARGC1A | interactor | 20 | 0.442 | 123.381 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
202 |
PPFIBP1 | oncoprotein | 9 | 0.393 | 5.804 | DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain XkdW (PF09636, IPR019094): XkdW protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding DUF3837 (PF12939, IPR024212): Domain of unknown function (DUF3837) |
203 |
PPP4R3A | interactor | 5 | 0.600 | 3.131 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 WH1 (PF00568, IPR000697, SM00461): WH1 domain DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
204 |
PRKAR1A | suppressor | 7 | 0.467 | 43.416 | RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain |
205 |
PRPF19 | protein found in more fusions | 20 | 0.421 | 56.711 | Prp19 (PF08606, IPR013915): Prp19/Pso4-like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
206 |
PRPF3 | protein found in more fusions | 14 | 0.359 | 29.501 | DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3) PWI (PF01480, IPR002483, SM00311): PWI domain TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) |
207 |
PRPF4 | interactor | 11 | 0.511 | 10.559 | PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
208 |
PRSS1 | interactor | 3 | 0.667 | 0.271 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
209 |
PTCD3 | interactor | 17 | 0.500 | 87.514 | PPR (PF01535, IPR002885): PPR repeat PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain |
210 |
QKI | protein found in more fusions | 24 | 0.549 | 150.003 | KH_1 (PF00013, IPR004088, SM00322): KH domain STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking |
211 |
RAD23A | oncoprotein | 10 | 0.417 | 36.178 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
212 |
RALY | interactor | 21 | 0.338 | 100.467 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
213 |
RARA | oncoprotein | 17 | 0.225 | 172.824 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
214 |
RAVER1 | interactor | 6 | 0.533 | 4.765 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
215 |
RBBP4 | oncoprotein | 14 | 0.440 | 40.048 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
216 |
RBM14 | suppressor | 23 | 0.336 | 173.559 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
217 |
RCN1 | interactor | 13 | 0.244 | 33.885 | EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
218 |
RCN2 | interactor | 6 | 0.600 | 1.661 | EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
219 |
RPL10 | suppressor | 66 | 0.664 | 213.865 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
220 |
RPL10A | interactor | 64 | 0.751 | 91.134 | Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family |
221 |
RPL11 | suppressor | 60 | 0.796 | 76.759 | Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5 Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus |
222 |
RPL12 | interactor | 56 | 0.865 | 52.196 | Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain |
223 |
RPL13 | interactor | 61 | 0.721 | 156.972 | Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e |
224 |
RPL13A | protein found in more fusions | 55 | 0.867 | 30.328 | Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13 |
225 |
RPL13P12 | interactor | 1 | 0 | 0 | NA |
226 |
RPL14 | interactor | 62 | 0.748 | 91.741 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family |
227 |
RPL15 | interactor | 57 | 0.844 | 34.041 | Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15 |
228 |
RPL18 | interactor | 60 | 0.822 | 66.294 | Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e |
229 |
RPL18A | interactor | 56 | 0.867 | 29.354 | Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A |
230 |
RPL19 | interactor | 59 | 0.801 | 66.341 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e |
231 |
RPL21 | interactor | 55 | 0.874 | 74.358 | Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e |
232 |
RPL23 | interactor | 60 | 0.780 | 88.403 | Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e |
233 |
RPL23A | interactor | 56 | 0.867 | 37.130 | Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23 Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain |
234 |
RPL24 | protein found in more fusions | 52 | 0.943 | 13.626 | MAS20 (PF02064, IPR002056): MAS20 protein import receptor Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e |
235 |
RPL27 | protein found in more fusions | 53 | 0.905 | 14.938 | Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family |
236 |
RPL27AP6 | interactor | 3 | 0.667 | 0.782 | NA |
237 |
RPL3 | protein found in more fusions | 60 | 0.808 | 72.500 | Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3 |
238 |
RPL30 | interactor | 52 | 0.914 | 24.607 | NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3 |
239 |
RPL31 | interactor | 58 | 0.761 | 110.971 | Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e |
240 |
RPL32P18 | interactor | 1 | 0 | 0 | NA |
241 |
RPL35 | interactor | 51 | 0.898 | 33.446 | Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein XFP_N (PF09364, IPR018970): XFP N-terminal domain |
242 |
RPL4 | interactor | 61 | 0.768 | 104.712 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
243 |
RPL5 | suppressor | 71 | 0.661 | 210.159 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
244 |
RPL6 | interactor | 79 | 0.548 | 584.836 | Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain |
245 |
RPL7 | interactor | 68 | 0.690 | 136.661 | Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain |
246 |
RPL7A | protein found in more fusions | 59 | 0.822 | 58.710 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
247 |
RPL8 | interactor | 60 | 0.756 | 110.978 | Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain |
248 |
RPLP0 | interactor | 67 | 0.709 | 147.412 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
249 |
RPLP2 | protein found in more fusions | 53 | 0.886 | 19.969 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
250 |
RPS10 | interactor | 58 | 0.780 | 206.204 | S10_plectin (PF03501, IPR005326): Plectin/S10 domain |
251 |
RPS11 | interactor | 60 | 0.738 | 228.541 | Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal |
252 |
RPS12 | interactor | 48 | 0.919 | 47.166 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
253 |
RPS13 | interactor | 58 | 0.858 | 41.308 | Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15 |
254 |
RPS14 | protein found in more fusions | 60 | 0.802 | 71.725 | Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11 |
255 |
RPS15A | interactor | 62 | 0.730 | 126.647 | Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8 |
256 |
RPS16 | interactor | 60 | 0.797 | 73.256 | Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16 |
257 |
RPS17 | interactor | 37 | 0.958 | 3.425 | Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17 |
258 |
RPS18 | protein found in more fusions | 56 | 0.845 | 75.274 | Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18 |
259 |
RPS19 | protein found in more fusions | 56 | 0.820 | 101.060 | Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e |
260 |
RPS2 | interactor | 63 | 0.758 | 115.408 | Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain |
261 |
RPS23 | interactor | 57 | 0.827 | 43.627 | Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23 |
262 |
RPS25 | interactor | 58 | 0.826 | 54.889 | Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein |
263 |
RPS26P11 | interactor | 1 | 0 | 0 | NA |
264 |
RPS3 | interactor | 64 | 0.729 | 119.203 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
265 |
RPS3A | interactor | 61 | 0.805 | 65.674 | Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family |
266 |
RPS4X | interactor | 69 | 0.685 | 208.023 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus |
267 |
RPS6 | protein found in more fusions | 63 | 0.766 | 99.126 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
268 |
RPS8 | interactor | 71 | 0.639 | 258.155 | Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e |
269 |
RPS9 | interactor | 55 | 0.894 | 37.990 | Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain S4 (PF01479, IPR002942, SM00363): S4 domain |
270 |
RUVBL1 | oncoprotein | 28 | 0.288 | 261.430 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
271 |
RXRA | oncoprotein | 16 | 0.371 | 64.540 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1 |
272 |
SDCCAG3 | interactor | 8 | 0.393 | 41.259 | GA (PF01468, IPR002988, SM00844): GA module TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein |
273 |
SEC16A | interactor | 14 | 0.231 | 119.757 | APC_r (PF05923): APC repeat Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region |
274 |
SETD7 | protein found in more fusions | 8 | 0.429 | 37.519 | MORN (PF02493, IPR003409, SM00698): MORN repeat MORN_2 (PF07661, IPR011652): MORN repeat variant SET (PF00856, IPR001214, SM00317): SET domain |
275 |
SGF29 | interactor | 8 | 0.464 | 141.259 | DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein |
276 |
SHMT2 | interactor | 21 | 0.252 | 169.359 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
277 |
SIK2 | interactor | 8 | 0.500 | 10.870 | Pkinase (PF00069, IPR000719): Protein kinase domain |
278 |
SIPA1L2 | interactor | 4 | 0.667 | 2.053 | IncA (PF04156, IPR007285): IncA protein PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Rap_GAP (PF02145, IPR000331): Rap/ran-GAP SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein |
279 |
SNRPD3 | interactor | 11 | 0.400 | 79.244 | LSM (PF01423, IPR001163): LSM domain |
280 |
SPICE1 | interactor | 16 | 0.292 | 114.357 | SPICE (PF15678, IPR031387): Centriole duplication and mitotic chromosome congression ANXA2R (PF15721, IPR031449): Annexin-2 receptor JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
281 |
SREBF1 | protein found in more fusions | 22 | 0.610 | 48.451 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
282 |
SRSF3 | oncoprotein | 18 | 0.366 | 63.301 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
283 |
SRSF7 | interactor | 19 | 0.363 | 166.889 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-CCHC (PF00098, IPR001878): Zinc knuckle |
284 |
SSX2IP | protein found in more fusions | 25 | 0.188 | 455.049 | ZapB (PF06005, IPR009252): Cell division protein ZapB ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding YqzH (PF14164, IPR025546): YqzH-like protein |
285 |
STN1 | interactor | 18 | 0.824 | 12.962 | STN1_2 (PF09170, IPR015253): CST, Suppressor of cdc thirteen homolog, complex subunit STN1 RUN (PF02759, IPR004012, SM00593): RUN domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain Stn1 (PF10451, IPR018856): Telomere regulation protein Stn1 |
286 |
SUPT3H | interactor | 14 | 0.615 | 33.942 | TFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093) |
287 |
SUPT6H | interactor | 7 | 0.429 | 19.935 | Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain Tex_N (PF09371, IPR018974): Tex-like protein N-terminal domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SH2_2 (PF14633, IPR000980): SH2 domain HHH_7 (PF14635, IPR032706): Helix-hairpin-helix motif YqgF (PF14639, IPR028231): Holliday-junction resolvase-like of SPT6 HTH_44 (PF14641, IPR028088): Helix-turn-helix DNA-binding domain of SPT6 PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DLD (PF14878, IPR027999): Death-like domain of SPT6 |
288 |
SUPT7L | interactor | 9 | 0.778 | 7.781 | Bromo_TP (PF07524, IPR006565): Bromodomain associated |
289 |
TADA2A | interactor | 45 | 0.310 | 748.764 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
290 |
TBKBP1 | interactor | 3 | 1.000 | 0 | Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Synthase_beta (PF11421, IPR020971): ATP synthase F1 beta subunit TBD (PF12845, IPR024581): TBD domain |
291 |
TCAF1 | interactor | 2 | 0 | 0.895 | Peptidase_M60 (PF13402, IPR031161): Peptidase M60, enhancin and enhancin-like |
292 |
TCL1B | oncoprotein | 17 | 0.750 | 43.569 | TCL1_MTCP1 (PF01840, IPR004832): TCL1/MTCP1 family |
293 |
TGS1 | interactor | 6 | 0.200 | 26.766 | DinI (PF06183, IPR010391): DinI-like family DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Methyltransf_15 (PF09445, IPR019012): RNA cap guanine-N2 methyltransferase Presenilin (PF01080, IPR001108): Presenilin |
294 |
THRA | suppressor | 17 | 0.342 | 96.081 | C1_2 (PF03107, IPR004146): C1 domain zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
295 |
THRAP3 | oncoprotein | 21 | 0.319 | 254.287 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family |
296 |
TNRC6A | interactor | 6 | 0.467 | 4.498 | CreD (PF06123, IPR010364): Inner membrane protein CreD RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Ago_hook (PF10427, IPR019486): Argonaute hook M_domain (PF12938, IPR026805): M domain of GW182 TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain |
297 |
TP53 | suppressor | 141 | 0.171 | 8592.780 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
298 |
TRA | oncoprotein | 8 | 0.607 | 3.183 | NA |
299 |
TRAP1 | oncoprotein | 14 | 0.451 | 21.294 | HSP90 (PF00183, IPR001404): Hsp90 protein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
300 |
TRIM28 | protein found in more fusions | 21 | 0.311 | 162.307 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
301 |
TRIM32 | suppressor | 9 | 0.357 | 142.470 | NHL (PF01436, IPR001258): NHL repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
302 |
TRIM37 | oncoprotein | 8 | 0.333 | 28.263 | MATH (PF00917, IPR002083, SM00061): MATH domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071) |
303 |
TRIP4 | interactor | 21 | 0.590 | 108.274 | ASCH (PF04266, IPR007374, SM01022): ASCH domain UxaC (PF02614, IPR003766): Glucuronate isomerase zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type |
304 |
TRRAP | interactor | 23 | 0.526 | 127.040 | BALF1 (PF06861, IPR010677): BALF1 protein BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) CLASP_N (PF12348, IPR024395): CLASP N terminal Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ (PF13513): HEAT-like repeat TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain ACDC (PF14733, IPR028078): AP2-coincident C-terminal |
305 |
TUBA1A | oncoprotein | 26 | 0.406 | 259.488 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
306 |
TUBA1B | protein found in more fusions | 13 | 0.372 | 47.885 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
307 |
TUBA1C | protein found in more fusions | 26 | 0.280 | 251.741 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
308 |
TUBB | protein found in more fusions | 29 | 0.431 | 137.605 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
309 |
TUBB2B | interactor | 11 | 0.455 | 12.151 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
310 |
TUBB3 | interactor | 9 | 0.417 | 16.638 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
311 |
TUBB4A | interactor | 5 | 0.600 | 1.521 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
312 |
TUBB4B | interactor | 22 | 0.476 | 48.795 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
313 |
TUBG1 | protein found in more fusions | 68 | 0.401 | 750.245 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
314 |
UBB | interactor | 9 | 0.306 | 84.652 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
315 |
UBR4 | interactor | 6 | 0.400 | 3.524 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pheromone (PF08015, IPR012597): Fungal mating-type pheromone RecR (PF02132, IPR023628): RecR protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) DZR (PF12773, IPR025874): Double zinc ribbon E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 FAM176 (PF14851): FAM176 family |
316 |
UBR5 | protein found in more fusions | 13 | 0.364 | 41.775 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
317 |
VASP | interactor | 9 | 0.393 | 7.896 | ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2 CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain WH1 (PF00568, IPR000697, SM00461): WH1 domain |
318 |
VDR | suppressor | 23 | 0.420 | 224.508 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
319 |
YBX3 | interactor | 6 | 0.467 | 8.003 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1) |
320 |
YWHAE | oncoprotein | 34 | 0.298 | 305.666 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
321 |
YWHAQ | interactor | 54 | 0.176 | 1346.186 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
322 |
ZC3H13 | interactor | 28 | 0.738 | 109.509 | FGF-BP1 (PF06473, IPR010510): FGF binding protein 1 (FGF-BP1) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) PET117 (PF15786, IPR031568): PET assembly of cytochrome c oxidase, mitochondrial |
323 |
ZC3HAV1 | interactor | 7 | 0.238 | 19.114 | PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain WWE (PF02825, IPR004170, SM00678): WWE domain |
324 |
ZKSCAN1 | interactor | 4 | 0.500 | 2.850 | CDC45 (PF02724, IPR003874): CDC45-like protein KRAB (PF01352, IPR001909, SM00349): KRAB box SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
325 |
ZNF281 | oncoprotein | 6 | 0.333 | 10.436 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger GRP (PF07172, IPR010800): Glycine rich protein family zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 zf-C2H2_4 (PF13894): C2H2-type zinc finger |
326 |
ZNF326 | interactor | 7 | 0.381 | 16.660 | AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) DUF678 (PF05077, IPR007769): Protein of unknown function (DUF678) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |