Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins MED1, CEP250 (from a repository: Thu Aug 22 20:29:34 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 326 The number (and %) of the onco-proteins 101 (30.98 %) The number (and %) of the tumor suppressors 28 (8.59 %) Total number of binary PPIs (saturation %) 4481 (8.46 %) The number (and %) of affected PPIs 327 (7.30 %) The number of possible different fusions 72 PPI diameter 4 PPI radius 2 The average degree of PPI 26.871 Assortativity coefficient -0.1491 The network average Clustering coefficient 0.472 The number (and %) of a zero Clustering coefficients 22 (6.75 %) The number (and %) of a zero Betweenness Centrality 20 (6.13 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: MED1,CEP250	All fusions
Proteins found in more fusions	PRPF19 (see 2 fusions); PLEKHA5 (see 2 fusions); DCAF1 (see 1 fusions); LGALS3BP (see 2 fusions); RPS18/TUBG1 (see 1 fusions); CCDC88A (see 3 fusions); APC (see 1 fusions); HDAC5 (see 1 fusions); DDX5 (see 1 fusions); HNRNPU/RPL24 (see 1 fusions); RPLP2 (see 1 fusions); RPL27/RPS6 (see 1 fusions); HUWE1 (see 4 fusions); HNF4A (see 1 fusions); BAG3 (see 4 fusions); POLR2E (see 1 fusions); SETD7 (see 2 fusions); POLR2A (see 2 fusions); DDX17 (see 4 fusions); EPAS1 (see 1 fusions); TUBA1B/TUBA1C (see 11 fusions); MATR3 (see 4 fusions); RPS19/RPS14 (see 1 fusions); TUBG1 (see 1 fusions); EEF1A1 (see 6 fusions); NTRK1/RPL7A (see 1 fusions); MYC (see 2 fusions); SSX2IP (see 1 fusions); SREBF1 (see 1 fusions); RARA (see 1 fusions); RXRA (see 2 fusions); EEF1A1/THRAP3 (see 1 fusions); HSP90AA1/TUBB (see 1 fusions); TP53 (see 3 fusions); MCM7 (see 2 fusions); TRIM28 (see 1 fusions); NAP1L4 (see 3 fusions); RPL5 (see 1 fusions); NCOA6 (see 1 fusions); PCBP2 (see 3 fusions); HNRNPC (see 1 fusions); CDK9 (see 2 fusions); VDR (see 2 fusions); RUVBL1 (see 1 fusions); PIAS1 (see 3 fusions); FTL (see 5 fusions); NDE1 (see 3 fusions); PRPF3 (see 1 fusions); APP (see 5 fusions); MAGED1 (see 1 fusions); MED21 (see 1 fusions); HSP90AA1 (see 6 fusions); HSP90AB1 (see 3 fusions); CLINT1 (see 2 fusions); MED1/MED13L (see 1 fusions); RPL3/RPL13A (see 1 fusions); TUBA1B/TUBA1A (see 2 fusions); QKI (see 3 fusions); EZH2 (see 1 fusions); DDB1 (see 4 fusions); MIB1 (see 4 fusions); EXOSC6 (see 1 fusions); CUL7 (see 2 fusions); KAT2B (see 1 fusions); ACTB (see 7 fusions); PARP1 (see 1 fusions); APP/GABPA (see 1 fusions); THRA (see 3 fusions); NR3C1 (see 8 fusions); PABPC1 (see 3 fusions); UBR5 (see 4 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	MED1	parental protein	94	0.230	5358.887	Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
2	CEP250	parental protein	233	0.087	34868.828	ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
3	ABR	oncoprotein	6	0.400	5.916	C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PH_10 (PF15411): Pleckstrin homology domain Tox-PL-2 (PF15643, IPR028910): Papain fold toxin 2
4	ACTB	oncoprotein	23	0.351	98.437	Actin (PF00022, IPR004000, SM00268): Actin
5	ADAMTS1	oncoprotein	1	0	0	ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1 Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
6	AGO2	interactor	13	0.333	100.492	ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
7	AKAP12	suppressor	2	0	0.782	OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain ROS_MUCR (PF05443, IPR008807): ROS/MUCR transcriptional regulator protein RII_binding_1 (PF10522, IPR018459): RII binding domain WSK (PF03832, IPR001573): WSK motif
8	ALYREF	interactor	18	0.471	89.434	FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
9	AMER1	suppressor	3	0.333	2.792	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region WTX (PF09422, IPR019003): WTX protein RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
10	AMOT	oncoprotein	10	0.167	41.003	FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162) Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
11	ANKIB1	interactor	1	0	0	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
12	APC	suppressor	9	0.250	51.833	APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
13	APP	protein found in more fusions	53	0.162	2432.661	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
14	AR	oncoprotein	21	0.237	180.174	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
15	ARHGEF2	oncoprotein	9	0.444	8.977	IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
16	ATM	suppressor	13	0.394	44.063	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
17	BAG3	oncoprotein	21	0.168	124.616	BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain
18	BORCS6	interactor	3	0.667	1.167	DUF2365 (PF10157, IPR019314): Uncharacterized conserved protein (DUF2365)
19	BRD4	oncoprotein	10	0.422	33.140	Caldesmon (PF02029, IPR006018): Caldesmon Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Stm1_N (PF09598, IPR019084): Stm1 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
20	CALU	interactor	5	0.400	2.368	EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
21	CCDC8	interactor	79	0.225	1511.922	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
22	CCDC87	interactor	3	0.667	3.481	MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
23	CCDC88A	protein found in more fusions	6	0.400	4.606	bZIP_1 (PF00170, IPR004827): bZIP transcription factor ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) HOOK (PF05622, IPR008636): HOOK protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL (PF10241, IPR019371): Uncharacterized conserved protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
24	CCNC	suppressor	33	0.790	109.642	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
25	CDK19	interactor	31	0.837	55.199	Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase (PF00069, IPR000719): Protein kinase domain
26	CDK8	interactor	49	0.533	577.257	Pkinase (PF00069, IPR000719): Protein kinase domain
27	CDK9	protein found in more fusions	35	0.191	763.160	Pkinase (PF00069, IPR000719): Protein kinase domain
28	CEP170	interactor	13	0.359	102.625	FHA (PF00498, IPR000253, SM00240): FHA domain DUF4254 (PF14063, IPR025350): Protein of unknown function (DUF4254) CEP170_C (PF15308, IPR029300): CEP170 C-terminus
29	CEP350	interactor	11	0.345	113.337	CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region MAS20 (PF02064, IPR002056): MAS20 protein import receptor Mucin (PF01456, IPR000458): Mucin-like glycoprotein Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment Complex1_LYR_2 (PF13233): Complex1_LYR-like AAA_23 (PF13476): AAA domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
30	CEP78	interactor	3	0.667	0.061	Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DUF3122 (PF11320, IPR021469): Protein of unknown function (DUF3122) LRR_6 (PF13516, IPR001611): Leucine Rich repeat
31	CLINT1	protein found in more fusions	9	0.429	19.121	ENTH (PF01417, IPR001026, SM00273): ENTH domain
32	CLSPN	interactor	3	0.333	4.792	Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) NinG (PF05766, IPR008713): Bacteriophage Lambda NinG protein Presenilin (PF01080, IPR001108): Presenilin PTS_IIB (PF02302, IPR003501): PTS system, Lactose/Cellobiose specific IIB subunit XAP5 (PF04921, IPR007005): XAP5, circadian clock regulator Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
33	COG3	interactor	3	0.333	1.410	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus OpuAC (PF04069, IPR007210): Substrate binding domain of ABC-type glycine betaine transport system Sec34 (PF04136, IPR007265): Sec34-like family Thioredoxin_6 (PF13848): Thioredoxin-like domain
34	CPNE7	suppressor	2	0	0.782	C2 (PF00168, IPR000008, SM00239): C2 domain Copine (PF07002, IPR010734): Copine Halo_GVPC (PF05465, IPR008639): Halobacterial gas vesicle protein C (GVPC) repeat
35	CRTC2	oncoprotein	5	0.400	4.423	TORC_N (PF12884, IPR024783): Transducer of regulated CREB activity, N terminus TORC_M (PF12885, IPR024784): Transducer of regulated CREB activity middle domain TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus
36	CTDP1	interactor	19	0.725	22.651	Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme FCP1_C (PF09309, IPR015388): FCP1, C-terminal NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A PTCB-BRCT (PF12738, IPR001357): twin BRCT domain HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
37	CUL7	protein found in more fusions	98	0.240	2265.381	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
38	DAP3	interactor	19	0.431	136.975	DAP3 (PF10236, IPR019368): Mitochondrial ribosomal death-associated protein 3
39	DCAF1	protein found in more fusions	13	0.500	34.204	DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
40	DDB1	protein found in more fusions	23	0.251	274.255	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
41	DDX17	protein found in more fusions	22	0.381	79.926	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
42	DDX21	interactor	22	0.584	34.283	CRT10 (PF08728, IPR014839): CRT10 DEAD (PF00270, IPR011545): DEAD/DEAH box helicase GUCT (PF08152, IPR012562): GUCT (NUC152) domain Sulfatase (PF00884, IPR000917): Sulfatase MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
43	DDX24	interactor	26	0.563	45.904	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Sec62 (PF03839, IPR004728): Translocation protein Sec62 Tti2 (PF10521, IPR018870): Tti2 family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
44	DDX41	interactor	5	0.500	1.476	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase zf-CCHC (PF00098, IPR001878): Zinc knuckle Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
45	DDX5	oncoprotein	33	0.363	258.721	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
46	DGCR14	interactor	2	0	0.782	Es2 (PF09751, IPR019148): Nuclear protein Es2
47	DHX15	interactor	23	0.379	76.112	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain
48	DHX9	oncoprotein	37	0.374	176.388	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
49	DOCK7	interactor	10	0.267	131.881	DHR-2 (PF06920, IPR010703): Dock homology region 2 DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398) DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins DOCK_N (PF16172, IPR032376): DOCK N-terminus
50	EEF1A1	suppressor	60	0.452	390.020	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
51	EIF4EBP3	interactor	1	0	0	eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
52	EIF4ENIF1	interactor	6	0.333	8.579	EIF4E-T (PF10477, IPR018862): Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
53	ELAVL1	oncoprotein	60	0.107	2436.153	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
54	EMC2	interactor	8	0.536	22.839	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_19 (PF14559): Tetratricopeptide repeat Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
55	ENO1	oncoprotein	18	0.288	137.811	Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
56	EPAS1	suppressor	26	0.610	244.919	Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
57	EPPK1	interactor	4	0.500	2.507	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HupF_HypC (PF01455, IPR001109): HupF/HypC family Plectin (PF00681, IPR001101, SM00250): Plectin repeat RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal
58	ESR1	suppressor	108	0.220	5081.843	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
59	ESR2	suppressor	34	0.333	474.607	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
60	EXOSC6	protein found in more fusions	6	0.300	8.261	RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
61	EZH2	suppressor	32	0.116	413.996	CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
62	F7	interactor	1	0	0	EGF (PF00008, IPR000742, SM00181): EGF-like domain Gla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Trypsin (PF00089, IPR001254, SM00020): Trypsin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
63	FAM120A	interactor	8	0.321	14.019	TPR_15 (PF13429): Tetratricopeptide repeat
64	FBL	interactor	44	0.474	478.677	Fibrillarin (PF01269, IPR000692): Fibrillarin
65	FBXW7	suppressor	43	0.422	753.450	Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like
66	FTL	protein found in more fusions	3	1.000	0	Ferritin (PF00210, IPR008331): Ferritin-like domain
67	GABPA	protein found in more fusions	2	0	0.549	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain GABP-alpha (PF11620, IPR024668): GA-binding protein alpha chain Wap1 (PF16997, IPR031550): Wap1 domain
68	GALNT18	interactor	1	0	0	Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2 Ricin_B_lectin (PF00652, IPR000772, SM00458): Ricin-type beta-trefoil lectin domain
69	GATA1	oncoprotein	4	0.500	4.133	GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain
70	GATA2	oncoprotein	6	0.267	35.475	GATA (PF00320, IPR000679, SM00401): GATA zinc finger
71	GIGYF1	interactor	4	0.333	3.093	GYF (PF02213, IPR003169, SM00444): GYF domain RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component) PRTase_3 (PF15610, IPR028944): PRTase ComF-like VIR_N (PF15912, IPR031801): Virilizer, N-terminal
72	GIGYF2	interactor	13	0.462	27.950	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
73	GJB5	interactor	1	0	0	Connexin (PF00029, IPR013092, SM00037): Connexin
74	GOLGA3	interactor	4	0.333	2.003	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 G-gamma (PF00631, IPR015898, SM00224): GGL domain SOGA (PF11365, IPR027881): Protein SOGA TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
75	GRPR	oncoprotein	1	0	0	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
76	GTF3C3	interactor	9	0.417	58.360	BUD22 (PF09073, IPR015158): BUD22 PGA2 (PF07543, IPR011431): Protein trafficking PGA2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369) ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat TPR_20 (PF14561): Tetratricopeptide repeat
77	GTF3C5	interactor	5	0.700	1.363	Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein Tau95 (PF09734, IPR019136): RNA polymerase III transcription factor (TF)IIIC subunit
78	H1FX	interactor	7	0.619	3.171	IGPS (PF00218, IPR013798): Indole-3-glycerol phosphate synthase
79	HAUS1	interactor	18	0.279	180.533	THP2 (PF09432, IPR018557): Tho complex subunit THP2 XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
80	HAUS5	interactor	7	0.476	15.835	HAUS5 (PF14817, IPR029131): HAUS augmin-like complex subunit 5
81	HAX1	interactor	7	0.571	8.984	Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
82	HBA1	interactor	3	0.667	0.998	Globin (PF00042, IPR000971): Globin
83	HBB	interactor	4	0.333	35.779	Globin (PF00042, IPR000971): Globin
84	HDAC5	protein found in more fusions	55	0.254	901.576	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
85	HERC2	interactor	15	0.275	179.199	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIB_HERC2 (PF06701, IPR010606): Mib_herc2 RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
86	HIST1H1C	oncoprotein	9	0.444	19.966	Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
87	HIST1H4H	interactor	3	0.667	0.057	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
88	HNF4A	suppressor	20	0.509	72.766	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
89	HNRNPC	protein found in more fusions	21	0.453	113.870	APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
90	HNRNPF	interactor	23	0.447	118.023	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
91	HNRNPH1	oncoprotein	21	0.519	46.050	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
92	HNRNPM	interactor	60	0.376	620.687	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
93	HNRNPR	interactor	33	0.366	216.285	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
94	HNRNPU	protein found in more fusions	95	0.358	1582.123	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
95	HOOK2	interactor	2	0	0	HOOK (PF05622, IPR008636): HOOK protein
96	HP1BP3	interactor	17	0.456	53.209	RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SDA1 (PF05285, IPR007949): SDA1 YL1 (PF05764, IPR008895): YL1 nuclear protein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
97	HSP90AA1	oncoprotein	58	0.243	1397.435	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
98	HSP90AB1	oncoprotein	41	0.456	149.185	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
99	HSPA1A	interactor	23	0.419	107.836	HSP70 (PF00012, IPR013126): Hsp70 protein
100	HSPA1L	interactor	11	0.527	20.421	HSP70 (PF00012, IPR013126): Hsp70 protein
101	HSPA2	interactor	12	0.500	28.640	HSP70 (PF00012, IPR013126): Hsp70 protein
102	HSPA5	oncoprotein	42	0.280	420.668	HSP70 (PF00012, IPR013126): Hsp70 protein
103	HSPA7	interactor	3	1.000	0	NA
104	HSPA8	oncoprotein	34	0.381	179.320	HSP70 (PF00012, IPR013126): Hsp70 protein
105	HSPA9	oncoprotein	19	0.415	44.646	HSP70 (PF00012, IPR013126): Hsp70 protein
106	HUWE1	oncoprotein	68	0.330	1157.913	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
107	IGF2BP1	oncoprotein	12	0.409	21.411	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain
108	IRS4	interactor	17	0.390	73.040	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence PH_11 (PF15413): Pleckstrin homology domain
109	KAT2A	interactor	19	0.386	117.487	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
110	KAT2B	protein found in more fusions	20	0.333	228.840	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
111	KIF1A	interactor	6	0.400	28.694	FHA (PF00498, IPR000253, SM00240): FHA domain IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain KIF1B (PF12423, IPR022140): Kinesin protein 1B Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF3694 (PF12473, IPR022164): Kinesin protein Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
112	LAS1L	interactor	4	0.667	0.963	BUD22 (PF09073, IPR015158): BUD22 eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus Las1 (PF04031, IPR007174): Las1-like NOA36 (PF06524, IPR010531): NOA36 protein CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
113	LGALS3BP	oncoprotein	28	0.385	93.619	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
114	LRCH2	interactor	2	1.000	0	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
115	LRPPRC	interactor	15	0.248	93.361	DED (PF01335, IPR001875, SM00031): Death effector domain MA3 (PF02847, IPR003891, SM00544): MA3 domain PPR (PF01535, IPR002885): PPR repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain TPR_19 (PF14559): Tetratricopeptide repeat PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
116	LZTFL1	interactor	3	0	1.108	Leu_zip (PF15294): Leucine zipper
117	LZTS2	suppressor	8	0.250	186.273	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127) Fez1 (PF06818): Fez1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
118	MAGED1	protein found in more fusions	11	0.267	32.965	MAGE (PF01454, IPR002190): MAGE family
119	MAGED2	interactor	21	0.395	206.774	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 MAGE (PF01454, IPR002190): MAGE family SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
120	MAP7D3	interactor	9	0.528	22.530	DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family Sec62 (PF03839, IPR004728): Translocation protein Sec62 Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa) ARGLU (PF15346): Arginine and glutamate-rich 1
121	MATR3	protein found in more fusions	26	0.383	125.105	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A
122	MBD3	interactor	8	0.333	29.135	DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
123	MCM7	protein found in more fusions	16	0.343	82.065	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
124	MDM2	oncoprotein	48	0.241	695.773	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
125	MED10	interactor	43	0.658	107.483	Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex
126	MED11	interactor	29	0.845	31.846	Med11 (PF10280, IPR019404): Mediator complex protein
127	MED12	oncoprotein	54	0.477	631.531	Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12 Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877) Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
128	MED13	oncoprotein	39	0.667	81.245	Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal
129	MED13L	protein found in more fusions	18	0.974	0.578	Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal
130	MED14	interactor	52	0.472	506.664	Med14 (PF08638, IPR013947): Mediator complex subunit MED14
131	MED15	interactor	40	0.645	74.284	Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
132	MED16	interactor	53	0.480	544.490	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Med16 (PF11635, IPR021665): Mediator complex subunit 16
133	MED17	oncoprotein	56	0.461	748.271	Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex
134	MED18	interactor	32	0.867	10.009	Med18 (PF09637, IPR019095): Med18 protein
135	MED19	interactor	39	0.733	74.542	Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
136	MED20	interactor	41	0.605	413.671	Med20 (PF08612, IPR013921): TATA-binding related factor (TRF) of subunit 20 of Mediator complex
137	MED21	protein found in more fusions	40	0.619	239.412	Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
138	MED22	interactor	27	0.812	91.043	Med22 (PF06179, IPR009332): Surfeit locus protein 5 subunit 22 of Mediator complex
139	MED23	interactor	57	0.444	994.088	Med23 (PF11573, IPR021629): Mediator complex subunit 23
140	MED24	interactor	53	0.478	388.890	Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal
141	MED25	interactor	35	0.581	116.125	Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A
142	MED26	interactor	43	0.650	107.161	Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
143	MED27	interactor	36	0.779	51.528	Med27 (PF11571, IPR021627): Mediator complex subunit 27
144	MED28	interactor	44	0.626	292.789	cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28
145	MED29	interactor	46	0.609	247.649	Med29 (PF11568, IPR021018): Mediator complex subunit 29
146	MED30	interactor	35	0.766	49.228	Med30 (PF11315, IPR021019): Mediator complex subunit 30
147	MED31	interactor	20	0.753	29.709	Med31 (PF05669, IPR008831): SOH1
148	MED4	interactor	67	0.313	2382.558	Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
149	MED6	interactor	42	0.653	131.527	Med6 (PF04934, IPR007018): MED6 mediator sub complex component Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase
150	MED7	interactor	40	0.662	152.279	Med7 (PF05983, IPR009244): MED7 protein DotU (PF09850, IPR017732): Type VI secretion system protein DotU
151	MED8	interactor	39	0.663	299.841	Med8 (PF10232, IPR019364): Mediator of RNA polymerase II transcription complex subunit 8
152	MED9	interactor	39	0.706	107.459	Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
153	MIB1	protein found in more fusions	10	0.417	35.453	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat MIB_HERC2 (PF06701, IPR010606): Mib_herc2 ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
154	MOGS	interactor	11	0.291	128.869	Glyco_hydro_63 (PF03200, IPR004888): Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N (PF16923, IPR031631): Glycosyl hydrolase family 63 N-terminal domain
155	MOV10	interactor	50	0.160	1263.276	AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain
156	MRPS14	interactor	9	0.833	2.315	Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e
157	MRPS18B	interactor	12	0.485	27.223	Ribosomal_S18 (PF01084, IPR001648): Ribosomal protein S18 HTH_21 (PF13276, IPR025948): HTH-like domain zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
158	MRPS2	interactor	15	0.571	49.943	Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
159	MRPS22	interactor	15	0.562	36.812	MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22
160	MRPS23	interactor	10	0.778	6.088	MRP-S23 (PF10484, IPR023611): Mitochondrial ribosomal protein S23
161	MRPS34	interactor	8	0.714	3.416	MRP-S34 (PF16053, IPR032053): Mitochondrial 28S ribosomal protein S34
162	MRPS35	interactor	11	0.709	8.167	MRP-S28 (PF10213, IPR019349): Mitochondrial ribosomal subunit protein
163	MRPS9	interactor	20	0.516	98.750	Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
164	MTMR1	interactor	1	0	0	GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain 3-PAP (PF12578, IPR022587): Myotubularin-associated protein Myb_CC_LHEQLE (PF14379, IPR025756): MYB-CC type transfactor, LHEQLE motif
165	MYC	oncoprotein	56	0.166	1406.824	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
166	MYH9	suppressor	18	0.386	66.748	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
167	N4BP2	interactor	2	0	0	CUE (PF02845, IPR003892, SM00546): CUE domain DUF1771 (PF08590, IPR013899, SM01162): Domain of unknown function (DUF1771) RyR (PF02026, IPR003032): RyR domain Smr (PF01713, IPR002625, SM00463): Smr domain AAA_22 (PF13401, IPR003593): AAA domain AAA_33 (PF13671): AAA domain
168	NAP1L4	protein found in more fusions	12	0.255	23.910	NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
169	NCOA6	oncoprotein	20	0.275	142.122	DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator
170	NDE1	protein found in more fusions	11	0.200	169.657	NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
171	NEK2	interactor	3	0	1.493	Pkinase (PF00069, IPR000719): Protein kinase domain
172	NEURL4	interactor	6	0.733	6.677	Neuralized (PF07177, IPR006573, SM00588): Neuralized
173	NINL	interactor	19	0.181	153.357	PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat TBCA (PF02970, IPR004226): Tubulin binding cofactor A DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389) Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein FAM184 (PF15665): Family with sequence similarity 184, A and B TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
174	NOC4L	interactor	2	1.000	0	CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
175	NOP2	interactor	37	0.605	139.099	BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F P120R (PF08062, IPR012586): P120R (NUC006) repeat Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477) FAM176 (PF14851): FAM176 family Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
176	NR1H2	oncoprotein	6	0.600	6.275	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
177	NR1I3	interactor	16	0.417	120.518	PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
178	NR3C1	protein found in more fusions	19	0.268	232.019	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
179	NTRK1	oncoprotein	133	0.122	7403.159	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
180	NUP43	interactor	3	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
181	NUP62	interactor	7	0.333	10.277	Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region
182	NXF1	interactor	50	0.099	989.391	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
183	PABPC1	oncoprotein	52	0.437	424.823	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT
184	PARD3B	interactor	1	0	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
185	PARP1	suppressor	41	0.235	685.329	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
186	PCBP2	protein found in more fusions	15	0.407	80.694	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
187	PCM1	oncoprotein	19	0.345	147.263	FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus FUSC (PF04632, IPR006726): Fusaric acid resistance protein family IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family AAA_23 (PF13476): AAA domain zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829)
188	PHLDB2	interactor	4	0.667	1.608	DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family PH (PF00169, IPR001849, SM00233): PH domain Synaptobrevin (PF00957, IPR001388): Synaptobrevin DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
189	PIAS1	suppressor	10	0.361	262.136	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
190	PIN1	suppressor	22	0.255	198.271	Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain
191	PKP2	interactor	6	0.467	3.978	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383)
192	PLEKHA5	protein found in more fusions	6	0.400	5.259	PH (PF00169, IPR001849, SM00233): PH domain WW (PF00397, IPR001202, SM00456): WW domain MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
193	PLK4	interactor	9	0.286	13.821	ABC1 (PF03109, IPR004147): ABC1 family Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
194	POLL	interactor	4	0	6.326	HHH (PF00633, IPR000445): Helix-hairpin-helix motif DNA_pol_lambd_f (PF10391, IPR018944): Fingers domain of DNA polymerase lambda HHH_5 (PF14520): Helix-hairpin-helix domain HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb DNA_pol_B_palm (PF14792, IPR028207): DNA polymerase beta palm BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
195	POLR2A	protein found in more fusions	52	0.228	1392.507	RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
196	POLR2E	protein found in more fusions	20	0.456	149.501	RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain
197	POLR2F	interactor	15	0.705	29.948	RNA_pol_Rpb6 (PF01192, IPR006110): RNA polymerase Rpb6
198	POLR2G	interactor	24	0.696	58.578	SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
199	POU1F1	interactor	6	0.467	5.358	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2
200	PPARG	suppressor	19	0.261	166.718	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
201	PPARGC1A	interactor	20	0.442	123.381	Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1
202	PPFIBP1	oncoprotein	9	0.393	5.804	DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain XkdW (PF09636, IPR019094): XkdW protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding DUF3837 (PF12939, IPR024212): Domain of unknown function (DUF3837)
203	PPP4R3A	interactor	5	0.600	3.131	Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 WH1 (PF00568, IPR000697, SM00461): WH1 domain DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
204	PRKAR1A	suppressor	7	0.467	43.416	RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
205	PRPF19	protein found in more fusions	20	0.421	56.711	Prp19 (PF08606, IPR013915): Prp19/Pso4-like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
206	PRPF3	protein found in more fusions	14	0.359	29.501	DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3) PWI (PF01480, IPR002483, SM00311): PWI domain TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
207	PRPF4	interactor	11	0.511	10.559	PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
208	PRSS1	interactor	3	0.667	0.271	Trypsin (PF00089, IPR001254, SM00020): Trypsin
209	PTCD3	interactor	17	0.500	87.514	PPR (PF01535, IPR002885): PPR repeat PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
210	QKI	protein found in more fusions	24	0.549	150.003	KH_1 (PF00013, IPR004088, SM00322): KH domain STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking
211	RAD23A	oncoprotein	10	0.417	36.178	UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
212	RALY	interactor	21	0.338	100.467	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
213	RARA	oncoprotein	17	0.225	172.824	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
214	RAVER1	interactor	6	0.533	4.765	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
215	RBBP4	oncoprotein	14	0.440	40.048	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
216	RBM14	suppressor	23	0.336	173.559	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
217	RCN1	interactor	13	0.244	33.885	EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
218	RCN2	interactor	6	0.600	1.661	EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
219	RPL10	suppressor	66	0.664	213.865	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
220	RPL10A	interactor	64	0.751	91.134	Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
221	RPL11	suppressor	60	0.796	76.759	Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5 Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
222	RPL12	interactor	56	0.865	52.196	Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
223	RPL13	interactor	61	0.721	156.972	Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
224	RPL13A	protein found in more fusions	55	0.867	30.328	Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
225	RPL13P12	interactor	1	0	0	NA
226	RPL14	interactor	62	0.748	91.741	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
227	RPL15	interactor	57	0.844	34.041	Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
228	RPL18	interactor	60	0.822	66.294	Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
229	RPL18A	interactor	56	0.867	29.354	Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
230	RPL19	interactor	59	0.801	66.341	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
231	RPL21	interactor	55	0.874	74.358	Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
232	RPL23	interactor	60	0.780	88.403	Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
233	RPL23A	interactor	56	0.867	37.130	Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23 Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
234	RPL24	protein found in more fusions	52	0.943	13.626	MAS20 (PF02064, IPR002056): MAS20 protein import receptor Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
235	RPL27	protein found in more fusions	53	0.905	14.938	Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
236	RPL27AP6	interactor	3	0.667	0.782	NA
237	RPL3	protein found in more fusions	60	0.808	72.500	Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
238	RPL30	interactor	52	0.914	24.607	NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
239	RPL31	interactor	58	0.761	110.971	Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
240	RPL32P18	interactor	1	0	0	NA
241	RPL35	interactor	51	0.898	33.446	Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein XFP_N (PF09364, IPR018970): XFP N-terminal domain
242	RPL4	interactor	61	0.768	104.712	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
243	RPL5	suppressor	71	0.661	210.159	Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
244	RPL6	interactor	79	0.548	584.836	Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
245	RPL7	interactor	68	0.690	136.661	Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
246	RPL7A	protein found in more fusions	59	0.822	58.710	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
247	RPL8	interactor	60	0.756	110.978	Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
248	RPLP0	interactor	67	0.709	147.412	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
249	RPLP2	protein found in more fusions	53	0.886	19.969	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
250	RPS10	interactor	58	0.780	206.204	S10_plectin (PF03501, IPR005326): Plectin/S10 domain
251	RPS11	interactor	60	0.738	228.541	Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
252	RPS12	interactor	48	0.919	47.166	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
253	RPS13	interactor	58	0.858	41.308	Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
254	RPS14	protein found in more fusions	60	0.802	71.725	Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
255	RPS15A	interactor	62	0.730	126.647	Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
256	RPS16	interactor	60	0.797	73.256	Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
257	RPS17	interactor	37	0.958	3.425	Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
258	RPS18	protein found in more fusions	56	0.845	75.274	Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
259	RPS19	protein found in more fusions	56	0.820	101.060	Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
260	RPS2	interactor	63	0.758	115.408	Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
261	RPS23	interactor	57	0.827	43.627	Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
262	RPS25	interactor	58	0.826	54.889	Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
263	RPS26P11	interactor	1	0	0	NA
264	RPS3	interactor	64	0.729	119.203	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
265	RPS3A	interactor	61	0.805	65.674	Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
266	RPS4X	interactor	69	0.685	208.023	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
267	RPS6	protein found in more fusions	63	0.766	99.126	Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
268	RPS8	interactor	71	0.639	258.155	Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
269	RPS9	interactor	55	0.894	37.990	Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain S4 (PF01479, IPR002942, SM00363): S4 domain
270	RUVBL1	oncoprotein	28	0.288	261.430	TIP49 (PF06068, IPR010339): TIP49 C-terminus
271	RXRA	oncoprotein	16	0.371	64.540	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
272	SDCCAG3	interactor	8	0.393	41.259	GA (PF01468, IPR002988, SM00844): GA module TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
273	SEC16A	interactor	14	0.231	119.757	APC_r (PF05923): APC repeat Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
274	SETD7	protein found in more fusions	8	0.429	37.519	MORN (PF02493, IPR003409, SM00698): MORN repeat MORN_2 (PF07661, IPR011652): MORN repeat variant SET (PF00856, IPR001214, SM00317): SET domain
275	SGF29	interactor	8	0.464	141.259	DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein
276	SHMT2	interactor	21	0.252	169.359	SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
277	SIK2	interactor	8	0.500	10.870	Pkinase (PF00069, IPR000719): Protein kinase domain
278	SIPA1L2	interactor	4	0.667	2.053	IncA (PF04156, IPR007285): IncA protein PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Rap_GAP (PF02145, IPR000331): Rap/ran-GAP SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein
279	SNRPD3	interactor	11	0.400	79.244	LSM (PF01423, IPR001163): LSM domain
280	SPICE1	interactor	16	0.292	114.357	SPICE (PF15678, IPR031387): Centriole duplication and mitotic chromosome congression ANXA2R (PF15721, IPR031449): Annexin-2 receptor JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
281	SREBF1	protein found in more fusions	22	0.610	48.451	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
282	SRSF3	oncoprotein	18	0.366	63.301	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
283	SRSF7	interactor	19	0.363	166.889	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-CCHC (PF00098, IPR001878): Zinc knuckle
284	SSX2IP	protein found in more fusions	25	0.188	455.049	ZapB (PF06005, IPR009252): Cell division protein ZapB ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding YqzH (PF14164, IPR025546): YqzH-like protein
285	STN1	interactor	18	0.824	12.962	STN1_2 (PF09170, IPR015253): CST, Suppressor of cdc thirteen homolog, complex subunit STN1 RUN (PF02759, IPR004012, SM00593): RUN domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain Stn1 (PF10451, IPR018856): Telomere regulation protein Stn1
286	SUPT3H	interactor	14	0.615	33.942	TFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093)
287	SUPT6H	interactor	7	0.429	19.935	Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain Tex_N (PF09371, IPR018974): Tex-like protein N-terminal domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SH2_2 (PF14633, IPR000980): SH2 domain HHH_7 (PF14635, IPR032706): Helix-hairpin-helix motif YqgF (PF14639, IPR028231): Holliday-junction resolvase-like of SPT6 HTH_44 (PF14641, IPR028088): Helix-turn-helix DNA-binding domain of SPT6 PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DLD (PF14878, IPR027999): Death-like domain of SPT6
288	SUPT7L	interactor	9	0.778	7.781	Bromo_TP (PF07524, IPR006565): Bromodomain associated
289	TADA2A	interactor	45	0.310	748.764	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
290	TBKBP1	interactor	3	1.000	0	Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Synthase_beta (PF11421, IPR020971): ATP synthase F1 beta subunit TBD (PF12845, IPR024581): TBD domain
291	TCAF1	interactor	2	0	0.895	Peptidase_M60 (PF13402, IPR031161): Peptidase M60, enhancin and enhancin-like
292	TCL1B	oncoprotein	17	0.750	43.569	TCL1_MTCP1 (PF01840, IPR004832): TCL1/MTCP1 family
293	TGS1	interactor	6	0.200	26.766	DinI (PF06183, IPR010391): DinI-like family DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Methyltransf_15 (PF09445, IPR019012): RNA cap guanine-N2 methyltransferase Presenilin (PF01080, IPR001108): Presenilin
294	THRA	suppressor	17	0.342	96.081	C1_2 (PF03107, IPR004146): C1 domain zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
295	THRAP3	oncoprotein	21	0.319	254.287	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
296	TNRC6A	interactor	6	0.467	4.498	CreD (PF06123, IPR010364): Inner membrane protein CreD RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Ago_hook (PF10427, IPR019486): Argonaute hook M_domain (PF12938, IPR026805): M domain of GW182 TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
297	TP53	suppressor	141	0.171	8592.780	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
298	TRA	oncoprotein	8	0.607	3.183	NA
299	TRAP1	oncoprotein	14	0.451	21.294	HSP90 (PF00183, IPR001404): Hsp90 protein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
300	TRIM28	protein found in more fusions	21	0.311	162.307	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
301	TRIM32	suppressor	9	0.357	142.470	NHL (PF01436, IPR001258): NHL repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
302	TRIM37	oncoprotein	8	0.333	28.263	MATH (PF00917, IPR002083, SM00061): MATH domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071)
303	TRIP4	interactor	21	0.590	108.274	ASCH (PF04266, IPR007374, SM01022): ASCH domain UxaC (PF02614, IPR003766): Glucuronate isomerase zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
304	TRRAP	interactor	23	0.526	127.040	BALF1 (PF06861, IPR010677): BALF1 protein BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) CLASP_N (PF12348, IPR024395): CLASP N terminal Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ (PF13513): HEAT-like repeat TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain ACDC (PF14733, IPR028078): AP2-coincident C-terminal
305	TUBA1A	oncoprotein	26	0.406	259.488	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
306	TUBA1B	protein found in more fusions	13	0.372	47.885	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
307	TUBA1C	protein found in more fusions	26	0.280	251.741	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
308	TUBB	protein found in more fusions	29	0.431	137.605	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
309	TUBB2B	interactor	11	0.455	12.151	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
310	TUBB3	interactor	9	0.417	16.638	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
311	TUBB4A	interactor	5	0.600	1.521	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
312	TUBB4B	interactor	22	0.476	48.795	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
313	TUBG1	protein found in more fusions	68	0.401	750.245	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
314	UBB	interactor	9	0.306	84.652	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
315	UBR4	interactor	6	0.400	3.524	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pheromone (PF08015, IPR012597): Fungal mating-type pheromone RecR (PF02132, IPR023628): RecR protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) DZR (PF12773, IPR025874): Double zinc ribbon E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 FAM176 (PF14851): FAM176 family
316	UBR5	protein found in more fusions	13	0.364	41.775	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
317	VASP	interactor	9	0.393	7.896	ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2 CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain WH1 (PF00568, IPR000697, SM00461): WH1 domain
318	VDR	suppressor	23	0.420	224.508	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
319	YBX3	interactor	6	0.467	8.003	CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1)
320	YWHAE	oncoprotein	34	0.298	305.666	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
321	YWHAQ	interactor	54	0.176	1346.186	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
322	ZC3H13	interactor	28	0.738	109.509	FGF-BP1 (PF06473, IPR010510): FGF binding protein 1 (FGF-BP1) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) PET117 (PF15786, IPR031568): PET assembly of cytochrome c oxidase, mitochondrial
323	ZC3HAV1	interactor	7	0.238	19.114	PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain WWE (PF02825, IPR004170, SM00678): WWE domain
324	ZKSCAN1	interactor	4	0.500	2.850	CDC45 (PF02724, IPR003874): CDC45-like protein KRAB (PF01352, IPR001909, SM00349): KRAB box SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
325	ZNF281	oncoprotein	6	0.333	10.436	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger GRP (PF07172, IPR010800): Glycine rich protein family zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 zf-C2H2_4 (PF13894): C2H2-type zinc finger
326	ZNF326	interactor	7	0.381	16.660	AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) DUF678 (PF05077, IPR007769): Protein of unknown function (DUF678) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated

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