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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CHI3L1, EDIL3 (from a repository: Sat Aug 3 01:11:20 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)13
The number (and %) of the onco-proteins2 (15.38 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)14 (17.95 %)
The number (and %) of affected PPIs11 (78.57 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI1.692
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients13 (100.00 %)
The number (and %) of a zero Betweenness Centrality11 (84.62 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: EDIL3,CHI3L1 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 EDIL3parental protein8056.000EGF (PF00008, IPR000742, SM00181): EGF-like domain
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
2 CHI3L1parental protein306.000Glyco_hydro_18 (PF00704, IPR001223): Glycosyl hydrolases family 18
3 ADGRL1interactor1007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
Gal_Lectin (PF02140, IPR000922): Galactose binding lectin domain
GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif
Latrophilin (PF02354, IPR003334): Latrophilin Cytoplasmic C-terminal region
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
HRM (PF02793, IPR001879, SM00008): Hormone receptor domain
GAIN (PF16489, IPR032471): GPCR-Autoproteolysis INducing (GAIN) domain
4 BREoncoprotein100BRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE)
5 CCDC8interactor200Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
6 CD55oncoprotein200Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
HYLS1_C (PF15311, IPR027918): Hydrolethalus syndrome protein 1 C-terminus
7 CDKL1interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
8 DGUOKinteractor200dNK (PF01712, IPR002624): Deoxynucleoside kinase
9 HAX1interactor100Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
10 ITGB5interactor100EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin beta chain VWA domain
PSI_integrin (PF17205): Integrin plexin domain
11 MTRF1Linteractor100PCRF (PF03462, IPR005139, SM00937): PCRF domain
RF-1 (PF00472, IPR000352): RF-1 domain
12 NUFIP1interactor100NUFIP1 (PF10453, IPR019496): Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1)
DUF3395 (PF11875, IPR024586): Domain of unknown function (DUF3395)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
13 TFinteractor100Transferrin (PF00405, IPR001156, SM00094): Transferrin

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