Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins HHLA3, PI3 (from a repository: Sat Jan 5 21:17:29 2019)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins1 (16.67 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)10 (66.67 %)
The number (and %) of affected PPIs4 (40.00 %)
The number of possible different fusions2
PPI diameter1
PPI radiusinf
The average degree of PPI2.333
Assortativity coefficient1.0000
The network average Clustering coefficient0.667
The number (and %) of a zero Clustering coefficients2 (33.33 %)
The number (and %) of a zero Betweenness Centrality6 (100.00 %)


List of the fusions

PPI for parental proteins: PI3,HHLA3 All fusions
Proteins found in more fusions CSTA (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 PI3parental protein31.0000WAP (PF00095, IPR008197, SM00217): WAP-type (Whey Acidic Protein) 'four-disulfide core'
Cementoin (PF10511, IPR019541): Trappin protein transglutaminase binding domain
2 HHLA3parental protein100NA
3 CSTAoncoprotein41.0000Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
4 KRT1interactor31.0000Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Keratin_2_head (PF16208, IPR032444): Keratin type II head
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
5 LORinteractor41.0000Loricrin (PF15847, IPR031700): Major keratinocyte cell envelope protein
6 NMIinteractor200IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)

B a c k    t o    T o p ⇑