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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)91
The number (and %) of the onco-proteins25 (27.47 %)
The number (and %) of the tumor suppressors10 (10.99 %)
Total number of binary PPIs (saturation %)290 (7.08 %)
The number (and %) of affected PPIs91 (31.38 %)
The number of possible different fusions17
PPI diameter2
PPI radiusinf
The average degree of PPI5.582
Assortativity coefficient-0.2394
The network average Clustering coefficient0.543
The number (and %) of a zero Clustering coefficients19 (20.88 %)
The number (and %) of a zero Betweenness Centrality42 (46.15 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: NFAT5,WWP2 All fusions
Proteins found in more fusions UBE2D2 (see 2 fusions); EWSR1 (see 2 fusions); RNF11 (see 1 fusions); SF1 (see 1 fusions); TRAF4 (see 1 fusions); HNRNPUL1 (see 1 fusions); UBE2G1 (see 1 fusions); ATN1 (see 1 fusions); CUL1 (see 3 fusions); PABPC1 (see 2 fusions); EZH2 (see 1 fusions); UBE2E1 (see 2 fusions); UBC (see 1 fusions); SFTPC (see 1 fusions); NFAT5 (see 2 fusions); MYC (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NFAT5parental protein100PI31_Prot_C (PF08577, IPR013886): PI31 proteasome regulator
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
2 WWP2parental protein900.0426590.094WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
3 ADARB1suppressor100dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
A_deamin (PF02137, IPR002466, SM00552): Adenosine-deaminase (editase) domain
4 AMOToncoprotein80.4299.567FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family
DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162)
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
5 AMOTL1interactor40.5001.286NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Presenilin (PF01080, IPR001108): Presenilin
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
6 ANKRD44oncoprotein40.6671.286Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
7 ARRDC1interactor21.0000Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
8 ARRDC3interactor21.0000Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
9 ARRDC4interactor100Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
10 ATN1protein found in more fusions40.6670.500Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
11 ATP6AP2interactor31.0000Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Renin_r (PF07850, IPR012493): Renin receptor-like protein
12 CDC34oncoprotein41.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
13 CEP131interactor21.0000DASH_Spc19 (PF08287, IPR013251): Spc19
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
DUF743 (PF05332, IPR007996): Protein of unknown function (DUF743)
DUF826 (PF05696, IPR008544): Protein of unknown function (DUF826)
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Histone_HNS (PF00816, IPR001801): H-NS histone family
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
UCR_hinge (PF02320, IPR023184): Ubiquinol-cytochrome C reductase hinge protein
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
DUF2284 (PF10050, IPR019271): Predicted metal-binding protein (DUF2284)
PRKCSH-like (PF12999, IPR028146): Glucosidase II beta subunit-like
Phage_holin_2_4 (PF16082, IPR032124): Bacteriophage holin family, superfamily II-like
14 CPSF6interactor50.9000.222RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
15 CPSF7interactor100.37820.427CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
16 CUL1suppressor170.28370.375Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
17 DGCR2interactor100UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
18 DIDO1suppressor100PHD (PF00628, IPR019787, SM00249): PHD-finger
SlyX (PF04102, IPR007236): SlyX
SPOC (PF07744, IPR012921): SPOC domain
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
19 DVL2interactor60.5004.333DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
20 EGR2suppressor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
21 EIF3Aoncoprotein30.6670.667DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
22 EWSR1oncoprotein150.34145.689RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
23 EZH2suppressor110.37818.567CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
24 FAM168Ainteractor70.5334.233TCRP1 (PF14944, IPR029247): Tongue Cancer Chemotherapy Resistant Protein 1
25 FAM189A2interactor100CD20 (PF04103, IPR007237): CD20-like family
26 FBXL15interactor21.0000LRV (PF01816, IPR004830): Leucine rich repeat variant
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
27 FBXL18interactor50.6002.556LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
28 FBXO11oncoprotein21.0000TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
F-box-like (PF12937, IPR001810): F-box-like
Beta_helix (PF13229): Right handed beta helix region
29 FIP1L1oncoprotein30.6670.222Fip1 (PF05182, IPR007854): Fip1 motif
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FAM176 (PF14851): FAM176 family
Auts2 (PF15336): Autism susceptibility gene 2 protein
30 HNRNPUL1protein found in more fusions90.5716.852Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
31 LDLRAD4interactor31.0000Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
DUF2615 (PF11027, IPR020309): Protein of unknown function (DUF2615)
32 LGALS9Binteractor100Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
33 LITAFsuppressor100zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
34 MKNK2interactor100ABC_trans_aux (PF03886, IPR005586): ABC-type transport auxiliary lipoprotein component
Pkinase (PF00069, IPR000719): Protein kinase domain
35 MOV10interactor100.33321.167AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
36 MYConcoprotein130.30338.167HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
37 NDFIP1interactor31.0000DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370)
WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
Comm (PF15957, IPR031878): Commissureless
38 NDFIP2interactor21.0000DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370)
39 NOTCH3suppressor40.8330.667Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
40 NTRK1oncoprotein280.148264.833I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
41 NXF1interactor140.21849.567NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
42 PABPC1oncoprotein60.6003.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
43 PAIP1interactor30.6670.667MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
44 PDCD6IPinteractor90.35715.222BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
45 PDLIM7interactor30.6670.500LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
46 POU5F1oncoprotein50.6671.500Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
47 PSMD10interactor40.6671.333Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
48 PTCH1suppressor21.0000Patched (PF02460, IPR003392): Patched family
49 PTENsuppressor90.41717.000DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
50 PTPN14oncoprotein50.7002.000FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
51 RNF11protein found in more fusions110.42219.400zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
52 RUSC1interactor21.0000RUN (PF02759, IPR004012, SM00593): RUN domain
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
SH3_9 (PF14604, IPR001452): Variant SH3 domain
53 S1PR1interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
Ninjurin (PF04923, IPR007007): Ninjurin
54 SCAMP3interactor21.0000SCAMP (PF04144, IPR007273): SCAMP family
55 SCN5Ainteractor100Ion_trans (PF00520, IPR005821): Ion transport protein
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239)
Na_trans_cytopl (PF11933, IPR024583): Cytoplasmic domain of voltage-gated Na+ ion channel
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
56 SCNN1Ainteractor21.0000ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
57 SCNN1Boncoprotein30.6671.000ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
58 SCNN1Ginteractor21.0000ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
59 SEC24Dinteractor31.0000Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
Transp_Tc5_C (PF04236, IPR007350): Tc5 transposase C-terminal domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
60 SF1protein found in more fusions70.6004.400UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
KH_1 (PF00013, IPR004088, SM00322): KH domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
61 SFTPCprotein found in more fusions200BRICHOS (PF04089, IPR007084, SM01039): BRICHOS domain
SP_C-Propep (PF08999, IPR015091): Surfactant protein C, N terminal propeptide
62 SMAD2suppressor80.5716.500MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
63 SMAD3oncoprotein100.41715.067MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
64 SMAD6interactor31.0000MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
65 SMAD7interactor60.6673.667MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
66 SNRPCinteractor80.5367.486zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
67 SORT1interactor21.0000Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal
Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3
68 SPG20interactor21.0000MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
Senescence (PF06911, IPR009686): Senescence-associated protein
69 TMEM132Ainteractor50.7003.000DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366)
TMEM132D_N (PF15705, IPR031435): Mature oligodendrocyte transmembrane protein, TMEM132D, N-term
TMEM132D_C (PF15706, IPR031436): Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
TMEM132 (PF16070, IPR031437): Transmembrane protein family 132
70 TMEM255Ainteractor100FAM70 (PF14967, IPR028014): FAM70 protein
71 TNK2interactor31.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GTPase_binding (PF09027, IPR015116): GTPase binding
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
UBA_4 (PF14555): UBA-like domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
72 TRAF4oncoprotein40.6670.500MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
73 TUBGCP2interactor40.8330.333Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
74 UBCprotein found in more fusions240.190179.571ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
75 UBE2D1interactor60.8001.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
76 UBE2D2oncoprotein70.6673.167UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
77 UBE2D3interactor51.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
78 UBE2E1protein found in more fusions41.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
79 UBE2E3interactor50.8330.667UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
80 UBE2G1protein found in more fusions200UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
81 UBE2J2interactor31.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
82 UBE2Kinteractor40.8330.667UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
83 UBE2L3interactor90.39314.500UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
84 UBP1interactor100CP2 (PF04516, IPR007604): CP2 transcription factor
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
85 USP7oncoprotein140.30843.189MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
86 VASPinteractor50.5001.286ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
87 VPS11interactor40.6670.571DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
VPS11_C (PF12451, IPR024763): Vacuolar protein sorting protein 11 C terminal
TPR_11 (PF13414, IPR011990): TPR repeat
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
88 VPS37Cinteractor50.4003.533Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
89 WBP1interactor100WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
90 WBP2interactor100GRAM (PF02893, IPR004182, SM00568): GRAM domain
Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36
91 WIPF1interactor100CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GRP (PF07172, IPR010800): Glycine rich protein family
WH2 (PF02205, IPR003124, SM00246): WH2 motif

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