1 |
ADRM1 | parental protein | 60 | 0.543 | 1515.973 | Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor GET2 (PF08690, IPR028143): GET complex subunit GET2 RPN13_C (PF16550, IPR032368): UCH-binding domain |
2 |
SMARCA4 | parental protein | 200 | 0.088 | 22065.991 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
3 |
ACTB | oncoprotein | 30 | 0.246 | 341.279 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
ACTC1 | interactor | 5 | 0.600 | 8.666 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ACTL6A | interactor | 32 | 0.413 | 257.527 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
ADD1 | interactor | 7 | 0.714 | 3.482 | Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal |
7 |
ADNP | interactor | 15 | 0.343 | 40.505 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding PHD_Oberon (PF07227, IPR032881): PHD - plant homeodomain finger protein E6 (PF00518, IPR001334): Early Protein (E6) zf-BED (PF02892, IPR003656, SM00614): BED zinc finger Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
8 |
AHR | suppressor | 11 | 0.644 | 3.611 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAS_4 (PF08448, IPR013656): PAS fold |
9 |
ANGPTL4 | suppressor | 5 | 0.900 | 0.133 | SlyX (PF04102, IPR007236): SlyX Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain |
10 |
APP | protein found in more fusions | 44 | 0.146 | 1389.076 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
11 |
AR | oncoprotein | 44 | 0.271 | 413.476 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
12 |
ARID1A | suppressor | 34 | 0.428 | 123.915 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
13 |
ARID1B | oncoprotein | 23 | 0.601 | 39.366 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin (PF01080, IPR001108): Presenilin DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) DUF2235 (PF09994, IPR018712): Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa Spt20 (PF12090, IPR021950): Spt20 family |
14 |
ARID2 | suppressor | 15 | 0.676 | 12.294 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
15 |
ATF3 | suppressor | 17 | 0.450 | 25.224 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
16 |
ATL2 | interactor | 4 | 0.667 | 5.078 | GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain |
17 |
ATP6V0D2 | interactor | 1 | 0 | 0 | vATP-synt_AC39 (PF01992, IPR002843): ATP synthase (C/AC39) subunit |
18 |
BAG1 | oncoprotein | 11 | 0.364 | 47.135 | BAG (PF02179, IPR003103, SM00264): BAG domain Presenilin (PF01080, IPR001108): Presenilin ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
19 |
BAZ1B | interactor | 13 | 0.397 | 19.683 | D5_N (PF08706, IPR014818, SM00885): D5 N terminal like DDT (PF02791, IPR004022, SM00571): DDT domain DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PHD (PF00628, IPR019787, SM00249): PHD-finger YL1 (PF05764, IPR008895): YL1 nuclear protein DDRGK (PF09756, IPR019153, SM01128): DDRGK domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635) Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 FAM176 (PF14851): FAM176 family WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif |
20 |
BCL6 | oncoprotein | 21 | 0.353 | 93.282 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
21 |
BCL7A | suppressor | 17 | 0.699 | 16.080 | BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 UPF0561 (PF10573, IPR018888): Uncharacterised protein family UPF0561 |
22 |
BCL7B | suppressor | 14 | 0.725 | 22.452 | BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region |
23 |
BCL7C | suppressor | 22 | 0.576 | 68.069 | BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region |
24 |
BIRC2 | oncoprotein | 5 | 0.667 | 1.674 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
25 |
BMI1 | oncoprotein | 22 | 0.362 | 95.007 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
26 |
BRCA1 | suppressor | 55 | 0.238 | 855.926 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
27 |
BRD4 | oncoprotein | 9 | 0.306 | 15.583 | Caldesmon (PF02029, IPR006018): Caldesmon Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Stm1_N (PF09598, IPR019084): Stm1 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
28 |
BRD7 | suppressor | 20 | 0.374 | 321.908 | HcyBio (PF01837, IPR002708): Homocysteine biosynthesis enzyme, sulfur-incorporation GntR (PF00392, IPR000524, SM00345): Bacterial regulatory proteins, gntR family Presenilin (PF01080, IPR001108): Presenilin Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3512 (PF12024, IPR021900): Domain of unknown function (DUF3512) MAJIN (PF15077, IPR027816): Membrane-anchored junction protein |
29 |
BRWD1 | interactor | 5 | 0.700 | 2.602 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex |
30 |
BYSL | interactor | 8 | 0.500 | 11.753 | Bystin (PF05291, IPR007955): Bystin MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1) |
31 |
CAD | oncoprotein | 20 | 0.458 | 94.380 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon |
32 |
CAND1 | interactor | 34 | 0.295 | 226.709 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
33 |
CARM1 | oncoprotein | 24 | 0.377 | 85.583 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
34 |
CAT | suppressor | 5 | 0.333 | 1.959 | Catalase (PF00199, IPR011614, SM01060): Catalase Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive |
35 |
CBX5 | suppressor | 19 | 0.314 | 43.377 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain |
36 |
CCDC74B | interactor | 20 | 1.000 | 0 | CCDC92 (PF14916): Coiled-coil domain of unknown function CCDC74_C (PF14917, IPR029422): Coiled coil protein 74, C terminal |
37 |
CCDC92 | interactor | 17 | 1.000 | 0 | Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit CCDC92 (PF14916): Coiled-coil domain of unknown function |
38 |
CCNE1 | oncoprotein | 15 | 0.410 | 60.130 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
39 |
CDC5L | interactor | 48 | 0.278 | 766.877 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
40 |
CDK19 | interactor | 8 | 0.607 | 6.728 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase (PF00069, IPR000719): Protein kinase domain |
41 |
CDK8 | interactor | 25 | 0.420 | 84.382 | Pkinase (PF00069, IPR000719): Protein kinase domain |
42 |
CDKN2A | suppressor | 22 | 0.403 | 127.153 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
43 |
CDX2 | suppressor | 6 | 0.533 | 7.141 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Caudal_act (PF04731, IPR006820): Caudal like protein activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
44 |
CDYL | interactor | 8 | 0.750 | 1.943 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase ECH_2 (PF16113, IPR032259): Enoyl-CoA hydratase/isomerase |
45 |
CEBPA | suppressor | 15 | 0.560 | 15.494 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
46 |
CEBPB | oncoprotein | 31 | 0.411 | 97.625 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
47 |
CHD4 | oncoprotein | 33 | 0.296 | 243.490 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Coilin_N (PF15862, IPR031722): Coilin N-terminus |
48 |
CHD7 | interactor | 9 | 0.861 | 1.700 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein Myb_DNA-bind_7 (PF15963): Myb DNA-binding like |
49 |
CHFR | suppressor | 8 | 0.810 | 0.644 | FHA (PF00498, IPR000253, SM00240): FHA domain Glyco_hydro_92 (PF07971, IPR012939): Glycosyl hydrolase family 92 zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) LAX (PF15681, IPR031393): Lymphocyte activation family X |
50 |
CHMP5 | interactor | 3 | 0 | 9.955 | Snf7 (PF03357, IPR005024): Snf7 |
51 |
CIITA | oncoprotein | 11 | 0.345 | 46.570 | NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
52 |
COPS5 | protein found in more fusions | 47 | 0.234 | 526.215 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
53 |
CPSF2 | interactor | 18 | 0.281 | 165.547 | RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain |
54 |
CREB1 | oncoprotein | 19 | 0.458 | 38.108 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
55 |
CREBBP | suppressor | 64 | 0.228 | 915.979 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
56 |
CTNNB1 | oncoprotein | 32 | 0.298 | 190.955 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
57 |
CUL3 | protein found in more fusions | 62 | 0.208 | 1215.294 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
58 |
DDX5 | oncoprotein | 29 | 0.317 | 124.616 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
59 |
DPF1 | interactor | 7 | 1.000 | 0 | PHD (PF00628, IPR019787, SM00249): PHD-finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ. PHD_4 (PF16866, IPR019787): PHD-finger |
60 |
DPF2 | interactor | 23 | 0.617 | 34.776 | PHD (PF00628, IPR019787, SM00249): PHD-finger zf-C2H2_4 (PF13894): C2H2-type zinc finger Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ. PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal Zf_RING (PF16744, IPR031946): KIAA1045 RING finger |
61 |
DPF3 | interactor | 21 | 0.671 | 36.151 | PHD (PF00628, IPR019787, SM00249): PHD-finger zf-C2H2_4 (PF13894): C2H2-type zinc finger Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ. Lar_restr_allev (PF14354): Restriction alleviation protein Lar |
62 |
EED | suppressor | 39 | 0.257 | 206.951 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
63 |
EGFR | oncoprotein | 32 | 0.247 | 437.485 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
64 |
EP400 | oncoprotein | 11 | 0.582 | 5.760 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide DDHD (PF02862, IPR004177, SM01127): DDHD domain GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase HSA (PF07529, IPR014012, SM00573): HSA Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3304 (PF11745, IPR021733): Protein of unknown function (DUF3304) DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573) Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain EP400_N (PF15790, IPR031575): E1A-binding protein p400, N-terminal |
65 |
EPAS1 | suppressor | 24 | 0.308 | 182.497 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
66 |
ESR1 | suppressor | 69 | 0.196 | 1257.223 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
67 |
FANCA | oncoprotein | 9 | 0.250 | 96.313 | Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus |
68 |
FBXO6 | interactor | 29 | 0.278 | 216.724 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
69 |
FKBP8 | protein found in more fusions | 34 | 0.843 | 57.960 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
70 |
FOXE1 | oncoprotein | 8 | 0.286 | 11.854 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
71 |
FOXO1 | suppressor | 12 | 0.655 | 4.014 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
72 |
GATA1 | oncoprotein | 15 | 0.486 | 16.991 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
73 |
GLI1 | suppressor | 8 | 0.821 | 0.742 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
74 |
GMNN | interactor | 4 | 0.500 | 0.684 | Geminin (PF07412, IPR022786): Geminin |
75 |
GTF3C3 | interactor | 14 | 0.385 | 31.829 | BUD22 (PF09073, IPR015158): BUD22 PGA2 (PF07543, IPR011431): Protein trafficking PGA2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369) ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat TPR_20 (PF14561): Tetratricopeptide repeat |
76 |
H2AFX | suppressor | 27 | 0.259 | 217.720 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
77 |
HDAC1 | suppressor | 81 | 0.208 | 1377.725 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
78 |
HDAC2 | suppressor | 66 | 0.221 | 873.828 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
79 |
HDAC3 | suppressor | 36 | 0.264 | 186.723 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
80 |
HDAC9 | interactor | 13 | 0.515 | 11.878 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 CEP19 (PF14933, IPR029412): CEP19-like protein |
81 |
HIF1A | suppressor | 29 | 0.421 | 147.522 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
82 |
HIST1H3A | interactor | 31 | 0.255 | 216.984 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
83 |
HIST1H3E | interactor | 24 | 0.275 | 199.930 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
84 |
HIST1H4F | interactor | 7 | 0.381 | 10.137 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
85 |
HIST2H2BE | interactor | 18 | 0.366 | 50.097 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
86 |
HIST2H3C | interactor | 11 | 0.255 | 24.153 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
87 |
HMGB1 | oncoprotein | 13 | 0.462 | 40.681 | HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
88 |
HNRNPC | protein found in more fusions | 26 | 0.347 | 90.833 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
89 |
HSF1 | protein found in more fusions | 11 | 0.422 | 33.844 | DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
90 |
HSF4 | interactor | 3 | 0.667 | 0.400 | Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
91 |
HSP90B1 | suppressor | 21 | 0.324 | 218.215 | CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region |
92 |
HSPB1 | oncoprotein | 31 | 0.326 | 404.979 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
93 |
HUWE1 | oncoprotein | 59 | 0.403 | 807.650 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
94 |
IKZF1 | suppressor | 16 | 0.400 | 94.857 | Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
95 |
ING1 | suppressor | 19 | 0.503 | 31.398 | PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta |
96 |
INSIG2 | interactor | 15 | 0.914 | 1.410 | INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG) |
97 |
IRF1 | suppressor | 7 | 0.762 | 1.120 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor |
98 |
JUNB | oncoprotein | 7 | 0.619 | 2.482 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
99 |
KDM6A | suppressor | 7 | 0.333 | 18.075 | JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat |
100 |
KLF1 | interactor | 11 | 0.655 | 7.182 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain EKLF_TAD1 (PF16832, IPR031786): Erythroid krueppel-like transcription factor, transactivation 1 EKLF_TAD2 (PF16833, IPR031784): Erythroid krueppel-like transcription factor, transactivation 2 |
101 |
KLF4 | suppressor | 8 | 0.571 | 7.179 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
102 |
KPNA1 | interactor | 19 | 0.333 | 70.864 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
103 |
KPNA2 | interactor | 21 | 0.329 | 93.237 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
104 |
LMNB1 | interactor | 10 | 0.267 | 23.806 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain |
105 |
MAML1 | interactor | 8 | 0.321 | 13.761 | MamL-1 (PF09596, IPR019082): MamL-1 domain Kri1 (PF05178, IPR018034): KRI1-like family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
106 |
MARK4 | oncoprotein | 4 | 0.500 | 2.772 | KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
107 |
MBD3 | interactor | 15 | 0.516 | 18.473 | DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain |
108 |
MCPH1 | suppressor | 8 | 0.643 | 1.902 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain MSP (PF01716, IPR002628): Manganese-stabilising protein / photosystem II polypeptide Spectrin (PF00435, IPR002017): Spectrin repeat Microcephalin (PF12258, IPR022047): Microcephalin protein PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
109 |
MDC1 | suppressor | 22 | 0.346 | 90.309 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
110 |
MDM2 | oncoprotein | 47 | 0.272 | 775.385 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
111 |
MED17 | oncoprotein | 15 | 0.276 | 82.279 | Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex |
112 |
MED6 | interactor | 8 | 0.714 | 4.653 | Med6 (PF04934, IPR007018): MED6 mediator sub complex component Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase |
113 |
MKL1 | oncoprotein | 5 | 0.700 | 2.542 | RPEL (PF02755, IPR004018, SM00707): RPEL repeat SAP (PF02037, IPR003034, SM00513): SAP domain Troponin-I_N (PF11636, IPR021666): Troponin I residues 1-32 |
114 |
MPP6 | interactor | 2 | 1.000 | 0 | L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
115 |
MX1 | interactor | 5 | 0.167 | 15.798 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
116 |
MYC | oncoprotein | 69 | 0.220 | 1909.816 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
117 |
MYEF2 | interactor | 9 | 0.389 | 15.972 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
118 |
MYO18A | interactor | 3 | 0.667 | 1.796 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
119 |
MYOCD | interactor | 6 | 0.533 | 4.133 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal IncA (PF04156, IPR007285): IncA protein RPEL (PF02755, IPR004018, SM00707): RPEL repeat SAP (PF02037, IPR003034, SM00513): SAP domain Totivirus_coat (PF05518, IPR008871): Totivirus coat protein |
120 |
MYOD1 | oncoprotein | 24 | 0.281 | 142.459 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5 |
121 |
MYOG | interactor | 5 | 0.500 | 2.133 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
122 |
NCOA1 | oncoprotein | 25 | 0.377 | 80.537 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
123 |
NCOR1 | oncoprotein | 35 | 0.368 | 132.840 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
124 |
NCOR2 | oncoprotein | 24 | 0.449 | 67.191 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
125 |
NEIL3 | interactor | 3 | 0.667 | 0.523 | Fapy_DNA_glyco (PF01149, IPR012319, SM00898): Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH (PF06831, IPR015886): Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-GRF (PF06839, IPR010666): GRF zinc finger zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
126 |
NEUROD1 | interactor | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain YL1 (PF05764, IPR008895): YL1 nuclear protein Neuro_bHLH (PF12533, IPR022575): Neuronal helix-loop-helix transcription factor |
127 |
NEUROG2 | interactor | 2 | 1.000 | 0 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Pacs-1 (PF10254, IPR019381): PACS-1 cytosolic sorting protein |
128 |
NF1 | suppressor | 4 | 0.667 | 0.287 | MIF4G_like_2 (PF09090, IPR015174): MIF4G like RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain MOR2-PAG1_C (PF14225, IPR025481): Cell morphogenesis C-terminal |
129 |
NFATC1 | oncoprotein | 15 | 0.410 | 24.972 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
130 |
NFE2L2 | oncoprotein | 13 | 0.538 | 20.670 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
131 |
NONO | oncoprotein | 28 | 0.373 | 81.312 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
132 |
NOP56 | interactor | 16 | 0.383 | 33.519 | Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal |
133 |
NOTCH1 | suppressor | 22 | 0.324 | 58.054 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
134 |
NPM1 | suppressor | 49 | 0.254 | 693.842 | Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
135 |
NR1H2 | oncoprotein | 5 | 0.900 | 0.182 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
136 |
NR2C1 | interactor | 14 | 0.604 | 9.096 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
137 |
NR3C1 | protein found in more fusions | 27 | 0.412 | 104.179 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
138 |
NR4A2 | oncoprotein | 9 | 0.444 | 9.895 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
139 |
NTRK1 | oncoprotein | 90 | 0.204 | 3482.937 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
140 |
OBSL1 | protein found in more fusions | 37 | 0.183 | 261.952 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
141 |
PAAF1 | interactor | 23 | 0.893 | 55.989 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
142 |
PABPN1 | interactor | 10 | 0.556 | 7.985 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Shadoo (PF14999, IPR029238): Shadow of prion protein, neuroprotective |
143 |
PAPD5 | interactor | 5 | 0.300 | 26.830 | NTP_transf_2 (PF01909, IPR002934): Nucleotidyltransferase domain PAP_assoc (PF03828, IPR002058): Cid1 family poly A polymerase Pheromone (PF08015, IPR012597): Fungal mating-type pheromone Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
144 |
PARD6A | interactor | 4 | 0.333 | 13.475 | PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
145 |
PARK2 | suppressor | 50 | 0.574 | 313.122 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
146 |
PAX6 | suppressor | 6 | 0.600 | 3.797 | PAX (PF00292, IPR001523, SM00351): 'Paired box' domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
147 |
PBRM1 | suppressor | 23 | 0.391 | 85.685 | BAH (PF01426, IPR001025, SM00439): BAH domain BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen Bromodomain (PF00439, IPR001487, SM00297): Bromodomain HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504) |
148 |
PBX1 | oncoprotein | 11 | 0.382 | 19.964 | PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
149 |
PELO | interactor | 8 | 0.500 | 5.798 | eRF1_1 (PF03463, IPR005140): eRF1 domain 1 eRF1_2 (PF03464, IPR005141): eRF1 domain 2 eRF1_3 (PF03465, IPR005142): eRF1 domain 3 |
150 |
PHB | suppressor | 25 | 0.330 | 88.392 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290) |
151 |
PHF10 | interactor | 10 | 0.911 | 0.824 | Herpes_MCP (PF03122, IPR000912): Herpes virus major capsid protein PHD (PF00628, IPR019787, SM00249): PHD-finger MRI (PF15325, IPR028278): Modulator of retrovirus infection |
152 |
PIPSL | interactor | 1 | 0 | 0 | NA |
153 |
PML | suppressor | 42 | 0.289 | 385.165 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
154 |
PMS2 | oncoprotein | 10 | 0.378 | 87.826 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain MORN_2 (PF07661, IPR011652): MORN repeat variant MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
155 |
POLR2A | protein found in more fusions | 31 | 0.255 | 207.907 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
156 |
POLR3A | interactor | 8 | 0.500 | 25.240 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 |
157 |
POLR3C | interactor | 5 | 0.500 | 20.502 | HTH_9 (PF08221, IPR013197): RNA polymerase III subunit RPC82 helix-turn-helix domain NIT (PF08376, IPR013587): Nitrate and nitrite sensing RNA_pol_Rpc82 (PF05645, IPR008806): RNA polymerase III subunit RPC82 HD_4 (PF13328, IPR003607): HD domain |
158 |
POLR3F | interactor | 3 | 1.000 | 0 | RNA_pol_Rpc34 (PF05158, IPR007832): RNA polymerase Rpc34 subunit |
159 |
PPARG | suppressor | 28 | 0.365 | 135.576 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
160 |
PPP1R2P4 | interactor | 4 | 1.000 | 0 | NA |
161 |
PRMT5 | protein found in more fusions | 23 | 0.333 | 99.716 | PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase |
162 |
PSMA1 | interactor | 47 | 0.775 | 136.359 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
163 |
PSMA2 | interactor | 49 | 0.767 | 108.843 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
164 |
PSMA3 | interactor | 56 | 0.576 | 457.019 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
165 |
PSMA4 | interactor | 43 | 0.801 | 203.898 | Proteasome (PF00227, IPR001353): Proteasome subunit U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
166 |
PSMA5 | oncoprotein | 46 | 0.735 | 219.995 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
167 |
PSMA6 | interactor | 50 | 0.686 | 223.216 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
168 |
PSMA7 | protein found in more fusions | 53 | 0.650 | 312.053 | Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
169 |
PSMB1 | interactor | 42 | 0.844 | 61.221 | Proteasome (PF00227, IPR001353): Proteasome subunit |
170 |
PSMB2 | interactor | 41 | 0.848 | 168.665 | Proteasome (PF00227, IPR001353): Proteasome subunit |
171 |
PSMB3 | protein found in more fusions | 43 | 0.793 | 138.885 | Proteasome (PF00227, IPR001353): Proteasome subunit |
172 |
PSMB4 | interactor | 41 | 0.817 | 93.612 | Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Proteasome (PF00227, IPR001353): Proteasome subunit |
173 |
PSMB5 | interactor | 41 | 0.841 | 104.094 | Proteasome (PF00227, IPR001353): Proteasome subunit |
174 |
PSMB6 | interactor | 39 | 0.884 | 35.187 | DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502) Proteasome (PF00227, IPR001353): Proteasome subunit |
175 |
PSMB7 | protein found in more fusions | 41 | 0.918 | 9.182 | Proteasome (PF00227, IPR001353): Proteasome subunit Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal |
176 |
PSMB8 | interactor | 35 | 0.979 | 1.449 | Proteasome (PF00227, IPR001353): Proteasome subunit |
177 |
PSMC1 | interactor | 59 | 0.596 | 288.052 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) DivIC (PF04977, IPR007060): Septum formation initiator DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815) Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
178 |
PSMC2 | interactor | 62 | 0.552 | 458.330 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
179 |
PSMC3 | interactor | 64 | 0.512 | 692.384 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
180 |
PSMC4 | interactor | 54 | 0.664 | 237.060 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain |
181 |
PSMC5 | protein found in more fusions | 63 | 0.538 | 854.655 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
182 |
PSMC6 | interactor | 56 | 0.631 | 198.296 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
183 |
PSMD1 | interactor | 60 | 0.572 | 376.851 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
184 |
PSMD10 | interactor | 30 | 0.736 | 100.203 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
185 |
PSMD11 | interactor | 54 | 0.635 | 480.772 | DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat |
186 |
PSMD12 | interactor | 53 | 0.681 | 161.497 | Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain |
187 |
PSMD13 | interactor | 51 | 0.683 | 265.983 | Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain |
188 |
PSMD14 | interactor | 51 | 0.734 | 82.972 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
189 |
PSMD2 | oncoprotein | 58 | 0.573 | 426.738 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
190 |
PSMD3 | interactor | 52 | 0.683 | 124.298 | Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate |
191 |
PSMD4 | interactor | 59 | 0.571 | 580.620 | UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |
192 |
PSMD6 | interactor | 47 | 0.777 | 114.136 | RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain |
193 |
PSMD7 | interactor | 46 | 0.816 | 42.197 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function Auts2 (PF15336): Autism susceptibility gene 2 protein Coilin_N (PF15862, IPR031722): Coilin N-terminus |
194 |
PSMD8 | interactor | 47 | 0.757 | 108.615 | CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family |
195 |
PSME1 | interactor | 27 | 0.889 | 17.869 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component) |
196 |
RAB5C | oncoprotein | 8 | 0.429 | 18.590 | Ras (PF00071, IPR001806, SM00173): Ras family |
197 |
RAD23A | oncoprotein | 46 | 0.733 | 167.296 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
198 |
RAD23B | suppressor | 28 | 0.603 | 141.240 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) |
199 |
RB1 | suppressor | 31 | 0.320 | 236.928 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
200 |
RBBP4 | oncoprotein | 42 | 0.275 | 499.889 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
201 |
RBL1 | suppressor | 13 | 0.564 | 10.976 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) |
202 |
RBL2 | suppressor | 8 | 0.607 | 2.299 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pap_E4 (PF02711, IPR003861): E4 protein RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain SLH (PF00395, IPR001119): S-layer homology domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) |
203 |
RBPJ | interactor | 14 | 0.308 | 44.566 | BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding TIG (PF01833, IPR002909): IPT/TIG domain |
204 |
RCOR1 | protein found in more fusions | 11 | 0.622 | 4.762 | DivIC (PF04977, IPR007060): Septum formation initiator ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain FAM76 (PF16046, IPR032017): FAM76 protein |
205 |
REEP5 | interactor | 3 | 0.667 | 0.833 | Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III TB2_DP1_HVA22 (PF03134, IPR004345): TB2/DP1, HVA22 family |
206 |
RELB | oncoprotein | 9 | 0.778 | 1.841 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain RelB_leu_zip (PF16180, IPR032399): RelB leucine zipper RelB_transactiv (PF16181, IPR032400): RelB transactivation domain |
207 |
REST | oncoprotein | 13 | 0.564 | 22.456 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Presenilin (PF01080, IPR001108): Presenilin RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain |
208 |
RNF2 | interactor | 41 | 0.244 | 478.752 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
209 |
RPS21 | interactor | 19 | 0.550 | 53.511 | Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e |
210 |
RPS6KA5 | interactor | 9 | 0.389 | 15.244 | Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
211 |
RPS8 | interactor | 24 | 0.435 | 143.469 | Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e |
212 |
RUNX1 | suppressor | 19 | 0.556 | 20.461 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
213 |
RXRA | oncoprotein | 19 | 0.379 | 110.265 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1 |
214 |
SCARNA22 | interactor | 12 | 0.258 | 15.799 | NA |
215 |
SETD7 | protein found in more fusions | 12 | 0.436 | 15.251 | MORN (PF02493, IPR003409, SM00698): MORN repeat MORN_2 (PF07661, IPR011652): MORN repeat variant SET (PF00856, IPR001214, SM00317): SET domain |
216 |
SHFM1 | interactor | 38 | 0.696 | 129.238 | CLLAC (PF15675, IPR031379): CLLAC-motif containing domain |
217 |
SIN3A | oncoprotein | 44 | 0.310 | 373.809 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
218 |
SIN3B | interactor | 15 | 0.562 | 16.637 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
219 |
SIRT7 | interactor | 34 | 0.235 | 447.309 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
220 |
SMAD2 | suppressor | 30 | 0.330 | 324.283 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
221 |
SMAD3 | oncoprotein | 42 | 0.293 | 539.986 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
222 |
SMARCA1 | interactor | 11 | 0.400 | 25.853 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain HAND (PF09110, IPR015194): HAND SLIDE (PF09111, IPR015195): SLIDE SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DBINO (PF13892, IPR020838): DNA-binding domain |
223 |
SMARCA2 | suppressor | 63 | 0.233 | 1000.224 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
224 |
SMARCAD1 | interactor | 22 | 0.429 | 47.621 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
225 |
SMARCB1 | suppressor | 58 | 0.270 | 646.001 | SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1 |
226 |
SMARCC1 | suppressor | 74 | 0.223 | 1042.147 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
227 |
SMARCC2 | interactor | 62 | 0.244 | 681.331 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
228 |
SMARCD1 | interactor | 45 | 0.323 | 348.839 | ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit DivIC (PF04977, IPR007060): Septum formation initiator SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain |
229 |
SMARCD2 | interactor | 27 | 0.519 | 75.507 | SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain |
230 |
SMARCD3 | interactor | 23 | 0.510 | 72.223 | SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain |
231 |
SMARCE1 | interactor | 53 | 0.279 | 471.523 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1) Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
232 |
SMC3 | oncoprotein | 22 | 0.299 | 86.069 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
233 |
SP1 | protein found in more fusions | 42 | 0.359 | 300.464 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
234 |
SRF | interactor | 14 | 0.423 | 29.965 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) |
235 |
SS18 | oncoprotein | 26 | 0.603 | 44.588 | SSXT (PF05030, IPR007726): SSXT protein (N-terminal region) Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor |
236 |
SS18L1 | oncoprotein | 15 | 0.429 | 20.199 | DUF1313 (PF07011, IPR009741): Protein of unknown function (DUF1313) SSXT (PF05030, IPR007726): SSXT protein (N-terminal region) |
237 |
STAT1 | suppressor | 24 | 0.308 | 134.307 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
238 |
STAT2 | oncoprotein | 9 | 0.444 | 8.337 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal |
239 |
STAT3 | suppressor | 27 | 0.397 | 94.414 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
240 |
STAT5A | suppressor | 12 | 0.436 | 13.275 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
241 |
STK11 | suppressor | 6 | 0.400 | 19.278 | Pkinase (PF00069, IPR000719): Protein kinase domain |
242 |
TAF10 | interactor | 8 | 0.357 | 10.338 | TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit |
243 |
TBX5 | suppressor | 2 | 1.000 | 0 | T-box (PF00907, IPR001699, SM00425): T-box |
244 |
TOP2B | oncoprotein | 20 | 0.405 | 54.058 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DASH_Spc19 (PF08287, IPR013251): Spc19 DNA_gyraseB (PF00204, IPR013506): DNA gyrase B DTHCT (PF08070, IPR012542): DTHCT (NUC029) region HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim (PF01751, IPR006171, SM00493): Toprim domain Anophelin (PF10731, IPR018932): Thrombin inhibitor from mosquito DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM |
245 |
TOPBP1 | protein found in more fusions | 8 | 0.524 | 4.542 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
246 |
TP53 | suppressor | 83 | 0.183 | 2478.090 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
247 |
TRIM28 | protein found in more fusions | 38 | 0.302 | 185.144 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
248 |
TXNL1 | interactor | 25 | 0.810 | 71.012 | PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin |
249 |
UBC | protein found in more fusions | 72 | 0.313 | 1639.233 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
250 |
UBE3A | oncoprotein | 27 | 0.415 | 262.515 | HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A |
251 |
UBQLN1 | protein found in more fusions | 19 | 0.732 | 23.908 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X |
252 |
UCHL5 | oncoprotein | 58 | 0.551 | 817.764 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
253 |
UPF1 | interactor | 11 | 0.582 | 4.546 | UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain) AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain |
254 |
USF1 | oncoprotein | 6 | 0.400 | 5.267 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
255 |
USP14 | interactor | 31 | 0.811 | 31.770 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
256 |
VAPA | interactor | 9 | 0.444 | 35.764 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain |
257 |
WDR77 | oncoprotein | 14 | 0.385 | 48.905 | LT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
258 |
WHSC1L1 | suppressor | 11 | 0.400 | 15.462 | PHD (PF00628, IPR019787, SM00249): PHD-finger Presenilin (PF01080, IPR001108): Presenilin PWWP (PF00855, IPR000313, SM00293): PWWP domain SET (PF00856, IPR001214, SM00317): SET domain zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
259 |
WWOX | suppressor | 17 | 0.316 | 28.081 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
260 |
ZEB1 | interactor | 4 | 1.000 | 0 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
261 |
ZMIZ2 | interactor | 4 | 0.833 | 0.122 | zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger |
262 |
ZMYND8 | oncoprotein | 6 | 0.933 | 0.286 | DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640) Mucin (PF01456, IPR000458): Mucin-like glycoprotein PHD (PF00628, IPR019787, SM00249): PHD-finger PWWP (PF00855, IPR000313, SM00293): PWWP domain RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 TCP (PF03634, IPR005333): TCP family transcription factor zf-MYND (PF01753, IPR002893): MYND finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3544 (PF12064, IPR021931): Domain of unknown function (DUF3544) CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand |