Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins TSPAN9, ACTR10 (from a repository: Sun Nov 24 13:19:35 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins6 (28.57 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)68 (32.38 %)
The number (and %) of affected PPIs19 (27.94 %)
The number of possible different fusions5
PPI diameter4
PPI radius2
The average degree of PPI5.905
Assortativity coefficient-0.2085
The network average Clustering coefficient0.642
The number (and %) of a zero Clustering coefficients3 (14.29 %)
The number (and %) of a zero Betweenness Centrality8 (38.10 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TSPAN9,ACTR10 All fusions
Proteins found in more fusions RABEP1 (see 1 fusions); KIF11 (see 1 fusions); DCTN1 (see 2 fusions); NAGK (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TSPAN9parental protein100Tetraspannin (PF00335, IPR018499): Tetraspanin family
2 ACTR10parental protein180.261182.164Actin (PF00022, IPR004000, SM00268): Actin
3 ACTR1Ainteractor80.8571.483Actin (PF00022, IPR004000, SM00268): Actin
4 ACTR1Binteractor110.58219.060Actin (PF00022, IPR004000, SM00268): Actin
5 C9orf24interactor21.0000SMRP1 (PF15181, IPR028195): Spermatid-specific manchette-related protein 1
6 CA10interactor21.0000Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
7 CAPZA2interactor100.62237.831F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
8 CSPP1interactor60.9330.250Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
IncA (PF04156, IPR007285): IncA protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578)
CCDC66 (PF15236): Coiled-coil domain-containing protein 66
9 DCTN1protein found in more fusions100.6678.917Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
FlgN (PF05130, IPR007809): FlgN protein
HOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
DUF2443 (PF10398, IPR019469): Protein of unknown function (DUF2443)
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Dynactin (PF12455, IPR022157): Dynein associated protein
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
10 DCTN2interactor120.61813.126Dynamitin (PF04912): Dynamitin
11 DCTN3interactor100.55617.833Dynactin_p22 (PF07426, IPR009991): Dynactin subunit p22
12 DCTN4interactor80.7145.333Dynactin_p62 (PF05502, IPR008603): Dynactin p62 family
13 ELAVL1oncoprotein5040.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
14 GPS2oncoprotein30.6670.250G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
15 KIF11protein found in more fusions40.33310.171Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
16 LMNB1interactor60.66719.581Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
17 LOC554223interactor21.0000NA
18 MYO19interactor41.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
19 NAGKprotein found in more fusions31.0000BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family
20 ORC6interactor100ORC6 (PF05460, IPR008721): Origin recognition complex subunit 6 (ORC6)
21 RABEP1oncoprotein41.0000Fib_succ_major (PF09603, IPR011871): Fibrobacter succinogenes major domain (Fib_succ_major)
Rab5-bind (PF09311, IPR015390): Rabaptin-like protein
Rabaptin (PF03528, IPR018514): Rabaptin

B a c k    t o    T o p ⇑