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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PDE10A, LOC112267908 (from a repository: Wed Aug 14 04:53:11 2019)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)3
The number (and %) of the onco-proteins1 (33.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)1 (33.33 %)
The number (and %) of affected PPIs1 (100.00 %)
The number of possible different fusions1
PPI diameter1
PPI radiusinf
The average degree of PPI0.667
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients3 (100.00 %)
The number (and %) of a zero Betweenness Centrality3 (100.00 %)


List of the fusions

PPI for parental proteins: LOC112267908,PDE10A All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 LOC112267908interactor000NA
2 PDE10Aparental protein100GAF (PF01590, IPR003018, SM00065): GAF domain
PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
3 TOP1oncoprotein100DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region

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