1 |
SEPT9 | parental protein | 53 | 0.117 | 2252.548 | Septin (PF00735, IPR000038): Septin DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
2 |
CABP1 | parental protein | 7 | 0 | 370.800 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
3 |
ANLN | oncoprotein | 10 | 0.444 | 17.856 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
4 |
APP | protein found in more fusions | 11 | 0.200 | 208.284 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
5 |
CACNA1A | interactor | 2 | 0 | 46.476 | Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
6 |
CACNA1C | interactor | 1 | 0 | 0 | Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain Ion_trans (PF00520, IPR005821): Ion transport protein Rer1 (PF03248, IPR004932): Rer1 family ODV-E18 (PF10717, IPR019655): Occlusion-derived virus envelope protein ODV-E18 DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) CAC1F_C (PF16885, IPR031688): Voltage-gated calcium channel subunit alpha, C-term GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
7 |
CDC42EP4 | interactor | 7 | 0.762 | 7.653 | PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain BORG_CEP (PF14957, IPR029273): Cdc42 effector |
8 |
CDC5L | interactor | 14 | 0.603 | 16.858 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
9 |
CFTR | suppressor | 8 | 0.381 | 10.400 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
10 |
COPA | protein found in more fusions | 10 | 0.500 | 17.908 | Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region COPI_C (PF06957, IPR010714): Coatomer (COPI) alpha subunit C-terminus WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
11 |
DDA1 | interactor | 2 | 1.000 | 0 | DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase |
12 |
EED | suppressor | 9 | 0.750 | 2.138 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
13 |
FERMT2 | interactor | 5 | 0.500 | 7.197 | FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
14 |
FLNB | oncoprotein | 5 | 0.500 | 2.022 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat PapC_N (PF13954, IPR025885): PapC N-terminal domain |
15 |
FN1 | oncoprotein | 12 | 0.242 | 41.704 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
16 |
FOS | oncoprotein | 3 | 0 | 86.431 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
17 |
GRK5 | protein found in more fusions | 4 | 0 | 161.864 | Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
18 |
HAUS1 | interactor | 3 | 1.000 | 0 | THP2 (PF09432, IPR018557): Tho complex subunit THP2 XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496) |
19 |
HIF1A | suppressor | 2 | 1.000 | 0 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
20 |
HNRNPD | oncoprotein | 11 | 0.622 | 7.829 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
21 |
HSPA5 | oncoprotein | 15 | 0.615 | 17.166 | HSP70 (PF00012, IPR013126): Hsp70 protein |
22 |
HSPD1 | suppressor | 12 | 0.561 | 28.758 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
23 |
IKBKG | interactor | 3 | 1.000 | 0 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
24 |
ITPR1 | interactor | 1 | 0 | 0 | Ins145_P3_rec (PF08709, IPR014821): Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans (PF00520, IPR005821): Ion transport protein MIR (PF02815, IPR016093, SM00472): MIR domain RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated RYDR_ITPR (PF01365, IPR000699): RIH domain CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit |
25 |
JPT1 | interactor | 1 | 0 | 0 | JUPITER (PF17054): Microtubule-Associated protein Jupiter |
26 |
MSH2 | suppressor | 6 | 0.900 | 0.250 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain |
27 |
NCL | protein found in more fusions | 9 | 0.500 | 99.691 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
28 |
NDUFV2 | interactor | 5 | 0.400 | 5.000 | 2Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin |
29 |
NEDD4 | suppressor | 4 | 0.667 | 1.800 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
30 |
NMT1 | oncoprotein | 2 | 0 | 142.362 | NMT (PF01233, IPR022676): Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C (PF02799, IPR022677): Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
31 |
NTRK1 | oncoprotein | 21 | 0.268 | 337.992 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
32 |
OBSL1 | interactor | 15 | 0.396 | 38.162 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
33 |
PPP3R1 | interactor | 1 | 0 | 0 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
34 |
RIDA | interactor | 3 | 1.000 | 0 | Ribonuc_L-PSP (PF01042, IPR006175): Endoribonuclease L-PSP |
35 |
SCO2 | interactor | 5 | 0.500 | 10.952 | SCO1-SenC (PF02630, IPR003782): SCO1/SenC |
36 |
SCP2 | interactor | 5 | 0.400 | 143.709 | SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain |
37 |
SEC22B | interactor | 8 | 0.286 | 17.556 | Synaptobrevin (PF00957, IPR001388): Synaptobrevin Longin (PF13774, IPR010908): Regulated-SNARE-like domain |
38 |
SEPT1 | interactor | 8 | 0.762 | 7.653 | Pet20 (PF08692, IPR014804): Mitochondrial protein Pet20 Septin (PF00735, IPR000038): Septin SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
39 |
SEPT11 | interactor | 12 | 0.439 | 29.319 | Septin (PF00735, IPR000038): Septin DUF3080 (PF11279, IPR021431): Protein of unknown function (DUF3080) |
40 |
SEPT2 | oncoprotein | 17 | 0.449 | 55.685 | FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Septin (PF00735, IPR000038): Septin |
41 |
SEPT3 | interactor | 8 | 0.952 | 0.286 | Septin (PF00735, IPR000038): Septin |
42 |
SEPT6 | oncoprotein | 13 | 0.500 | 22.071 | Septin (PF00735, IPR000038): Septin DUF2959 (PF11172, IPR021342): Protein of unknown function (DUF2959) |
43 |
SEPT7 | interactor | 15 | 0.514 | 31.526 | Fez1 (PF06818): Fez1 Septin (PF00735, IPR000038): Septin |
44 |
SH3KBP1 | protein found in more fusions | 8 | 0.810 | 4.411 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
45 |
SNW1 | protein found in more fusions | 16 | 0.543 | 34.287 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
46 |
SRRM2 | interactor | 15 | 0.467 | 197.327 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
47 |
STK11 | suppressor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
48 |
SUCLG1 | interactor | 3 | 0.667 | 0.667 | CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain Ligase_CoA (PF00549, IPR005811): CoA-ligase CoA_binding_2 (PF13380, IPR003781): CoA binding domain |
49 |
SUCLG2 | interactor | 4 | 0.500 | 2.167 | ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Ligase_CoA (PF00549, IPR005811): CoA-ligase |
50 |
SVIL | interactor | 4 | 0.500 | 2.667 | Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695) |
51 |
TIMM44 | interactor | 4 | 0.667 | 3.667 | Tim44 (PF04280, IPR007379, SM00978): Tim44-like domain DUF4211 (PF13926, IPR025451): Domain of unknown function (DUF4211) AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 RecG_N (PF17190): RecG N-terminal helical domain |
52 |
TMED9 | interactor | 3 | 0.667 | 0.500 | EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD |
53 |
TOR1AIP1 | interactor | 2 | 1.000 | 0 | LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C) Pap_E4 (PF02711, IPR003861): E4 protein |
54 |
TPM3 | oncoprotein | 6 | 0.400 | 3.327 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
55 |
U2AF2 | protein found in more fusions | 14 | 0.692 | 9.053 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
56 |
UBXN6 | interactor | 3 | 0.667 | 2.000 | PUB (PF09409, IPR018997): PUB domain UBX (PF00789, IPR001012, SM00166): UBX domain |
57 |
UQCRFS1 | interactor | 2 | 1.000 | 0 | Rieske (PF00355, IPR017941): Rieske [2Fe-2S] domain Ubiq-Cytc-red_N (PF09165, IPR015248): Ubiquinol-cytochrome c reductase 8 kDa, N-terminal UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region |
58 |
UQCRFS1P1 | interactor | 1 | 0 | 0 | NA |
59 |
VAMP2 | interactor | 3 | 1.000 | 0 | Synaptobrevin (PF00957, IPR001388): Synaptobrevin PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
60 |
VAPB | interactor | 5 | 0.500 | 11.556 | ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit ZapB (PF06005, IPR009252): Cell division protein ZapB Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain |
61 |
VMA21 | interactor | 1 | 0 | 0 | VMA21 (PF09446, IPR019013): VMA21-like domain |
62 |
XPO1 | interactor | 11 | 0.364 | 28.465 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |