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Fusion ID: Protein names:	108 4508
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Visualization interactions

Cytoscape Web for: parental proteins ATP6, ADCY2 (from a repository: Wed Oct 2 02:15:27 2019)

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Statistics and Network structure information

Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	5
The number (and %) of the onco-proteins	3 (60.00 %)
The number (and %) of the tumor suppressors	0 (0.00 %)
Total number of binary PPIs (saturation %)	5 (50.00 %)
The number (and %) of affected PPIs	3 (60.00 %)
The number of possible different fusions	3
PPI diameter	2
PPI radius	inf
The average degree of PPI	1.200
Assortativity coefficient	0
The network average Clustering coefficient	0.000
The number (and %) of a zero Clustering coefficients	5 (100.00 %)
The number (and %) of a zero Betweenness Centrality	4 (80.00 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: ADCY2,ATP6	All fusions
Proteins found in more fusions	ADCY5 (see 1 fusions); GNAS (see 5 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	ADCY2	parental protein	2	0	2.000	DUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053) HNOBA (PF07701, IPR011645): Heme NO binding associated Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain DUF3487 (PF11990, IPR021877): Protein of unknown function (DUF3487) DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131) AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
2	ATP6	parental protein	1	0	0	ATP-synt_A (PF00119, IPR000568): ATP synthase A chain
3	ADCY5	protein found in more fusions	2	0	0	DUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053) HNOBA (PF07701, IPR011645): Heme NO binding associated Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain DUF3566 (PF12089, IPR021949): Transmembrane domain of unknown function (DUF3566) DUF4191 (PF13829, IPR025445): Domain of unknown function (DUF4191) HILPDA (PF15220, IPR026190): Hypoxia-inducible lipid droplet-associated AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
4	FANCC	oncoprotein	1	0	0	Fanconi_C (PF02106, IPR000686): Fanconi anaemia group C protein
5	GNAS	oncoprotein	2	0	0	G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit

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