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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ALCAM, LOC107985072 (from a repository: Thu Aug 22 21:18:33 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)9
The number (and %) of the onco-proteins4 (44.44 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)14 (38.89 %)
The number (and %) of affected PPIs7 (50.00 %)
The number of possible different fusions3
PPI diameter2
PPI radiusinf
The average degree of PPI2.444
Assortativity coefficient-0.3743
The network average Clustering coefficient0.484
The number (and %) of a zero Clustering coefficients3 (33.33 %)
The number (and %) of a zero Betweenness Centrality6 (66.67 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LOC107985072,ALCAM All fusions
Proteins found in more fusions LGALS3 (see 2 fusions); EGFR (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LOC107985072interactor000NA
2 ALCAMparental protein70.19030.000C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366)
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
3 ART3interactor100ART (PF01129, IPR000768): NAD:arginine ADP-ribosyltransferase
4 CD6oncoprotein100SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
TMEM154 (PF15102, IPR028064): TMEM154 protein family
5 EGFRoncoprotein50.5003.000Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
6 LGALS3oncoprotein40.6671.000Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
7 LGALS8interactor21.0000Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
8 LGALS9interactor21.0000Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
Peptidase_C62 (PF12380, IPR024348): Gill-associated viral 3C-like peptidase
9 NTRK1oncoprotein31.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain

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