Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins POLQ, SLC30A7 (from a repository: Sat Jul 27 10:34:06 2019)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)18
The number (and %) of the onco-proteins4 (22.22 %)
The number (and %) of the tumor suppressors1 (5.56 %)
Total number of binary PPIs (saturation %)19 (12.42 %)
The number (and %) of affected PPIs16 (84.21 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.889
Assortativity coefficient-0.2919
The network average Clustering coefficient0.112
The number (and %) of a zero Clustering coefficients15 (83.33 %)
The number (and %) of a zero Betweenness Centrality17 (94.44 %)


List of the fusions

PPI for parental proteins: POLQ,SLC30A7 All fusions
Proteins found in more fusions CD40 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 POLQparental protein100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DNA_pol_A (PF00476, IPR001098, SM00482): DNA polymerase family A
DUF4332 (PF14229, IPR025567): Domain of unknown function (DUF4332)
2 SLC30A7parental protein150.010208.000Cation_efflux (PF01545, IPR002524): Cation efflux family
3 AP2S1interactor100Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
4 B3GNT3interactor100Galactosyl_T (PF01762, IPR002659): Galactosyltransferase
5 CD40protein found in more fusions200Glycophorin_A (PF01102, IPR001195): Glycophorin A
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
6 CHRNA9interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
7 CLPSL1interactor100Toxin_3 (PF00537, IPR002061): Scorpion toxin-like domain
8 ELAVL1oncoprotein200RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
9 KATNA1interactor100AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ABC_tran (PF00005, IPR003439): ABC transporter
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
AAA_22 (PF13401, IPR003593): AAA domain
10 LPAR1oncoprotein21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
11 LYPD3oncoprotein21.0000DUF753 (PF05444, IPR008472): Protein of unknown function (DUF753)
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
12 LYPD6interactor100UPAR_LY6_2 (PF16975): Ly6/PLAUR domain-containing protein 6, Lypd6
13 MRPL1interactor100CUB_2 (PF02408, IPR003366): CUB-like domain
Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
14 P2RY12interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
15 RIC3interactor100CHASE3 (PF05227, IPR007891): CHASE3 domain
RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3
16 SPINT2suppressor100Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
17 TCTN3interactor100DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
18 WBP1interactor100WBP-1 (PF11669, IPR021684): WW domain-binding protein 1

B a c k    t o    T o p ⇑