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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CHRM3, NRG3 (from a repository: Fri Sep 14 04:58:21 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins2 (33.33 %)
The number (and %) of the tumor suppressors2 (33.33 %)
Total number of binary PPIs (saturation %)6 (40.00 %)
The number (and %) of affected PPIs4 (66.67 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.333
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients6 (100.00 %)
The number (and %) of a zero Betweenness Centrality5 (83.33 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: NRG3,CHRM3 All fusions
Proteins found in more fusions ARF1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NRG3interactor000EGF (PF00008, IPR000742, SM00181): EGF-like domain
Neuregulin (PF02158, IPR002154): Neuregulin family
2 CHRM3parental protein4012.0007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
GWT1 (PF06423, IPR009447): GWT1
3 ARF1suppressor200Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
4 ARF6oncoprotein100Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
5 CSNK1A1suppressor100Pkinase (PF00069, IPR000719): Protein kinase domain
6 SEToncoprotein200NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)

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