Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PDPN, PKIG (from a repository: Mon Aug 19 05:06:52 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors1 (12.50 %)
Total number of binary PPIs (saturation %)8 (28.57 %)
The number (and %) of affected PPIs6 (75.00 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI1.750
Assortativity coefficient0.0000
The network average Clustering coefficient0.263
The number (and %) of a zero Clustering coefficients5 (62.50 %)
The number (and %) of a zero Betweenness Centrality7 (87.50 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: PDPN,PKIG All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 PDPNparental protein100Podoplanin (PF05808, IPR008783): Podoplanin
Sensor (PF13796, IPR025828): Putative sensor
2 PKIGparental protein50.10018.000PKI (PF02827, IPR004171): cAMP-dependent protein kinase inhibitor
3 KPTNinteractor21.0000AcetylCoA_hyd_C (PF13336, IPR026888): Acetyl-CoA hydrolase/transferase C-terminal domain
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
BBS2_Mid (PF14783, IPR029429): Ciliary BBSome complex subunit 2, middle region
4 MEOX2interactor100Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
5 PRKACAinteractor100Pkinase (PF00069, IPR000719): Protein kinase domain
6 RAB25suppressor21.0000Ras (PF00071, IPR001806, SM00173): Ras family
7 RPA3interactor200Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
8 TOM1L1interactor100GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain

B a c k    t o    T o p ⇑