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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins TIMM9, LOC105379506 (from a repository: Thu May 23 09:53:53 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)27
The number (and %) of the onco-proteins5 (18.52 %)
The number (and %) of the tumor suppressors2 (7.41 %)
Total number of binary PPIs (saturation %)63 (17.95 %)
The number (and %) of affected PPIs25 (39.68 %)
The number of possible different fusions4
PPI diameter2
PPI radiusinf
The average degree of PPI4.074
Assortativity coefficient-0.2752
The network average Clustering coefficient0.579
The number (and %) of a zero Clustering coefficients4 (14.81 %)
The number (and %) of a zero Betweenness Centrality9 (33.33 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LOC105379506,TIMM9 All fusions
Proteins found in more fusions PRDX6 (see 1 fusions); SFPQ (see 6 fusions); BAG3 (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LOC105379506interactor000NA
2 TIMM9parental protein250.100490.667zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
3 ATF2oncoprotein200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
4 BAG3oncoprotein50.6672.000BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
5 COX5Ainteractor30.6671.000COX5A (PF02284, IPR003204): Cytochrome c oxidase subunit Va
6 CTSAinteractor21.0000Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
7 DHX9oncoprotein30.6670.667DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
8 HNRNPMinteractor30.6670.667RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
9 HTRA2suppressor40.6670.667Peptidase_S32 (PF05579, IPR008760): Equine arteritis virus serine endopeptidase S32
PDZ_2 (PF13180, IPR001478): PDZ domain
Trypsin_2 (PF13365): Trypsin-like peptidase domain
10 MPSTinteractor50.5004.667Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
11 NADK2interactor30.6670.667NAD_kinase (PF01513, IPR002504): ATP-NAD kinase
12 NDUFV1interactor60.4677.333Complex1_51K (PF01512, IPR011538): Respiratory-chain NADH dehydrogenase 51 Kd subunit
NADH_4Fe-4S (PF10589, IPR019575, SM00928): NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
SLBB (PF10531, IPR019554): SLBB domain
13 NIT2suppressor21.0000CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase
14 NUDCinteractor100CS (PF04969, IPR007052): CS domain
D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc.
NuDC (PF16273, IPR032572): Nuclear distribution C domain
15 OXCT1interactor60.5005.000CoA_trans (PF01144, IPR004165, SM00882): Coenzyme A transferase
16 PRDX6protein found in more fusions40.6671.000AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
17 PTGES3interactor200CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
18 SART1interactor60.5004.667SART-1 (PF03343, IPR005011): SART-1 family
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
19 SEC22Binteractor30.6671.000Synaptobrevin (PF00957, IPR001388): Synaptobrevin
Longin (PF13774, IPR010908): Regulated-SNARE-like domain
20 SFPQoncoprotein60.5004.667GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
21 SLC25A6interactor40.8330.667Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
22 THOP1interactor21.0000Peptidase_M3 (PF01432, IPR001567): Peptidase family M3
23 TIMM10interactor70.47610.333zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
24 TIMM13interactor50.6003.667zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
25 TIMM8Ainteractor31.0000dDENN (PF03455, IPR005112, SM00801): dDENN domain
zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
26 TIMM8Binteractor21.0000zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
27 UQCRFS1interactor40.8330.667Rieske (PF00355, IPR017941): Rieske [2Fe-2S] domain
Ubiq-Cytc-red_N (PF09165, IPR015248): Ubiquinol-cytochrome c reductase 8 kDa, N-terminal
UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region

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