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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)121
The number (and %) of the onco-proteins34 (28.10 %)
The number (and %) of the tumor suppressors8 (6.61 %)
Total number of binary PPIs (saturation %)899 (12.38 %)
The number (and %) of affected PPIs120 (13.35 %)
The number of possible different fusions24
PPI diameter4
PPI radius2
The average degree of PPI13.983
Assortativity coefficient-0.2197
The network average Clustering coefficient0.535
The number (and %) of a zero Clustering coefficients4 (3.31 %)
The number (and %) of a zero Betweenness Centrality8 (6.61 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: AMFR,SCML2 All fusions
Proteins found in more fusions LMNA (see 4 fusions); SYVN1 (see 1 fusions); VCP (see 4 fusions); TRIM25 (see 2 fusions); UBE2G1 (see 1 fusions); EEF1A1 (see 6 fusions); TRIM28 (see 1 fusions); KPNB1 (see 2 fusions); RPL5 (see 1 fusions); PSMB3 (see 1 fusions); UBE2N (see 1 fusions); FAF1 (see 3 fusions); UBE2D2 (see 1 fusions); PSMB7 (see 2 fusions); MYH9/OS9 (see 1 fusions); INSIG1 (see 1 fusions); MAVS (see 1 fusions); PSMA7 (see 5 fusions); HTT (see 1 fusions); SARAF/FAF2 (see 1 fusions); OS9 (see 2 fusions); UBC (see 7 fusions); CRMP1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AMFRparental protein1110.1076716.823CUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
2 SCML2parental protein90.38943.784MBT (PF02820, IPR004092, SM00561): mbt repeat
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SLED (PF12140, IPR021987): SLED domain
Ashwin (PF15323, IPR024887): Developmental protein
RBR (PF17208): RNA binding Region
3 ADRA1Dinteractor40.8330.4577tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
4 ADRB2interactor190.30156.8527tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
5 AIFM1oncoprotein70.28621.674Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
AIF-MLS (PF14962, IPR032773): Mitochondria Localisation Sequence
6 ATP2A2interactor80.46410.020Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
7 ATXN3interactor80.5244.596Josephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
8 AUP1interactor120.51518.570CUE (PF02845, IPR003892, SM00546): CUE domain
9 BAG1oncoprotein60.20027.451BAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
10 BAG6interactor190.37387.340DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
11 BMI1oncoprotein140.28277.203zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
12 BRI3BPinteractor201.487HemY_N (PF07219, IPR010817): HemY protein N-terminus
BRI3BP (PF14965): Negative regulator of p53/TP53
CLZ (PF16526, IPR032406): C-terminal leucine zipper domain of cyclic nucleotide-gated channels
13 CANXinteractor180.294111.472Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
14 CBX8interactor70.60010.753Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RBR (PF17208): RNA binding Region
CBX7_C (PF17218): CBX family C-terminal motif
15 CCDC47interactor50.5007.708DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
16 CD3Dinteractor60.6004.043DAP10 (PF07213, IPR009861): DAP10 membrane protein
ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
17 CD82suppressor100Tetraspannin (PF00335, IPR018499): Tetraspanin family
18 CFTRsuppressor220.219130.145ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
19 CRMP1protein found in more fusions70.6672.833Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
20 CSE1Loncoprotein90.52810.461CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus
Cse1 (PF08506, IPR013713): Cse1
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
21 CYP2E1interactor100p450 (PF00067, IPR001128): Cytochrome P450
22 CYP3A4interactor40.6671.000p450 (PF00067, IPR001128): Cytochrome P450
23 DERL1interactor180.41241.265DER1 (PF04511, IPR007599): Der1-like family
24 DERL2interactor120.63611.105DER1 (PF04511, IPR007599): Der1-like family
25 DERL3interactor100DER1 (PF04511, IPR007599): Der1-like family
26 DGAT2interactor21.0000DAGAT (PF03982, IPR007130): Diacylglycerol acyltransferase
27 DHFRinteractor31.0000DHFR_1 (PF00186, IPR001796): Dihydrofolate reductase
28 EEF1A1suppressor120.36431.451GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
29 ELAVL1oncoprotein250.221240.958RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
30 ERLIN1interactor110.47313.877Ribosomal_L33 (PF00471, IPR001705): Ribosomal protein L33
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
31 ERLIN2interactor340.225291.108Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
32 FAF1protein found in more fusions130.7275.995UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
33 FAF2protein found in more fusions330.321214.930DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
34 GET4interactor120.62116.782DUF410 (PF04190, IPR007317): Protein of unknown function (DUF410)
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
35 GPIinteractor21.0000PGI (PF00342, IPR001672): Phosphoglucose isomerase
36 HAX1interactor70.6672.465Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
37 HECW2interactor130.22796.376C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
38 HERPUD1oncoprotein80.6798.655Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
39 HMGCRoncoprotein100.6226.853HMG-CoA_red (PF00368, IPR002202): Hydroxymethylglutaryl-coenzyme A reductase
Sterol-sensing (PF12349, IPR000731): Sterol-sensing domain of SREBP cleavage-activation
40 HSP90B1suppressor120.5919.781CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
41 HSPA4interactor160.33375.371Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
42 HSPA5oncoprotein240.39973.863HSP70 (PF00012, IPR013126): Hsp70 protein
43 HSPD1suppressor110.61810.062Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
44 HTR3Einteractor21.0000Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
45 HTTprotein found in more fusions80.4298.704HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
46 INSIG1protein found in more fusions100.6395.161INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
47 INSIG2interactor140.48422.645INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
48 ITPR1interactor50.7000.683Ins145_P3_rec (PF08709, IPR014821): Inositol 1,4,5-trisphosphate/ryanodine receptor
Ion_trans (PF00520, IPR005821): Ion transport protein
MIR (PF02815, IPR016093, SM00472): MIR domain
RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated
RYDR_ITPR (PF01365, IPR000699): RIH domain
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
49 KPNB1protein found in more fusions140.32145.254Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
50 LMNAprotein found in more fusions100.22250.064Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
51 MAVSprotein found in more fusions60.5002.632Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat
CARD_2 (PF16739, IPR031964): Caspase recruitment domain
52 MDC1suppressor70.33314.245FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
53 MGRN1interactor120.21238.371zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
54 MYH10interactor41.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
55 MYH9suppressor80.60711.520IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
56 NPLOC4interactor190.43389.382NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
57 NTRK1oncoprotein500.185756.021I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
58 OS9protein found in more fusions120.6736.758DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87
PRKCSH (PF07915, IPR012913): Glucosidase II beta subunit-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
59 OSBPL8interactor40.3339.082CDC45 (PF02724, IPR003874): CDC45-like protein
DUF1980 (PF09323, IPR015402): Domain of unknown function (DUF1980)
Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH (PF00169, IPR001849, SM00233): PH domain
60 PDIA2interactor30.6670.587Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
61 PHC2interactor60.8001.400SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-CGNR (PF11706, IPR021005): CGNR zinc finger
DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692)
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
62 PMP22interactor40.6670.693PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
63 POU5F1oncoprotein110.11146.110Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
64 PSMA1interactor250.78320.737Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
65 PSMA2interactor280.68436.627Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
66 PSMA3interactor310.572115.183Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
67 PSMA4interactor210.8815.026Proteasome (PF00227, IPR001353): Proteasome subunit
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
68 PSMA5oncoprotein230.83810.148Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
69 PSMA6interactor250.69746.690Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
70 PSMA7protein found in more fusions280.64784.014Proteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
71 PSMB1interactor250.68358.607Proteasome (PF00227, IPR001353): Proteasome subunit
72 PSMB2interactor210.85225.704Proteasome (PF00227, IPR001353): Proteasome subunit
73 PSMB3protein found in more fusions240.75533.141Proteasome (PF00227, IPR001353): Proteasome subunit
74 PSMB4interactor230.75921.899Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Proteasome (PF00227, IPR001353): Proteasome subunit
75 PSMB5interactor210.82444.153Proteasome (PF00227, IPR001353): Proteasome subunit
76 PSMB6interactor220.8578.833DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502)
Proteasome (PF00227, IPR001353): Proteasome subunit
77 PSMB7protein found in more fusions260.660149.280Proteasome (PF00227, IPR001353): Proteasome subunit
Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal
78 PSMC2interactor250.69248.233AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
79 PSMD14interactor230.79417.223JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
80 PSMD3interactor210.85225.520Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
81 PSMD6interactor190.9591.189RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
82 PSME4interactor150.9520.843Filament (PF00038, IPR001664): Intermediate filament protein
HEAT (PF02985, IPR000357): HEAT repeat
DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
BLM10_mid (PF16507, IPR032430): Proteasome-substrate-size regulator, mid region
83 RHOT1interactor40.8330.143EF_assoc_1 (PF08355, IPR013566): EF hand associated
EF_assoc_2 (PF08356, IPR013567): EF hand associated
Ras (PF00071, IPR001806, SM00173): Ras family
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
84 RNF2interactor280.168472.046zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
85 RNF5interactor170.25065.204zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
86 RPL5suppressor60.6001.297Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
87 SARAFprotein found in more fusions70.7622.301SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
88 SEC61Binteractor70.7331.490Sec61_beta (PF03911, IPR016482): Sec61beta family
89 SEL1Loncoprotein120.56112.885fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
90 SELENOSinteractor120.56112.924Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
DUF3326 (PF11805, IPR021763): Protein of unknown function (DUF3326)
91 SOD1interactor40.6670.200Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
92 SRPRBinteractor80.46412.322MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
93 SVIPinteractor80.6793.480SVIP (PF15811, IPR031632): Small VCP/p97-interacting protein
94 SYVN1protein found in more fusions420.221533.573Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
95 TCP1interactor60.60016.024Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
96 TIMM50interactor60.53314.586NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
97 TMUB1interactor40.8330.469DUF347 (PF03988, IPR007136): Repeat of Unknown Function (DUF347)
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF4227 (PF14004, IPR025321): Protein of unknown function (DUF4227)
98 TOM1L1interactor60.40020.633GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
99 TRIM25protein found in more fusions120.30943.631Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
100 TRIM28protein found in more fusions130.34861.375ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
101 UBAC2interactor80.7861.800Rhomboid (PF01694, IPR022764): Rhomboid family
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
102 UBCprotein found in more fusions540.206871.068ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
103 UBE2D1interactor130.40935.675UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
104 UBE2D2oncoprotein120.45517.507UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
105 UBE2D3interactor130.37948.760UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
106 UBE2D4interactor60.4004.421UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
107 UBE2G1protein found in more fusions40.6671.321UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
108 UBE2G2interactor70.6003.405UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
109 UBE2Kinteractor70.5718.715UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
110 UBE2Nprotein found in more fusions90.4296.919UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
111 UBE2Tinteractor40.6670.286UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
112 UBE2Winteractor60.5004.088UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
113 UBL4Ainteractor230.36088.271ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
114 UBXN1interactor160.57121.699Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UBX (PF00789, IPR001012, SM00166): UBX domain
115 UBXN4interactor90.50010.414Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
116 UBXN7interactor110.6917.634UBX (PF00789, IPR001012, SM00166): UBX domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
117 UFD1Linteractor180.47136.441UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
118 USP13interactor100.7564.389UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
119 USP7oncoprotein190.320170.559MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
120 VCPprotein found in more fusions520.203759.095AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
121 YOD1interactor90.7223.016OTU (PF02338, IPR003323): OTU-like cysteine protease
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain

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