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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins N4BP2L2, TFG (from a repository: Sun Jul 21 06:54:05 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)131
The number (and %) of the onco-proteins31 (23.66 %)
The number (and %) of the tumor suppressors12 (9.16 %)
Total number of binary PPIs (saturation %)556 (6.53 %)
The number (and %) of affected PPIs130 (23.38 %)
The number of possible different fusions20
PPI diameter5
PPI radius3
The average degree of PPI7.802
Assortativity coefficient-0.2473
The network average Clustering coefficient0.439
The number (and %) of a zero Clustering coefficients32 (24.43 %)
The number (and %) of a zero Betweenness Centrality44 (33.59 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TFG,N4BP2L2 All fusions
Proteins found in more fusions CUL4A (see 4 fusions); MAGED1 (see 1 fusions); TRIM25 (see 2 fusions); MAPK1IP1L (see 1 fusions); CUL7 (see 2 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); GRB2 (see 1 fusions); RBPMS (see 1 fusions); CHMP1A (see 2 fusions); EWSR1 (see 1 fusions); STAT5B (see 1 fusions); CLINT1 (see 2 fusions); MCM2 (see 1 fusions); TSG101 (see 2 fusions); COPS5 (see 1 fusions); ITSN1 (see 2 fusions); TFG/NTRK1 (see 1 fusions); CRMP1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TFGparental protein1180.05212341.475ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
2 N4BP2L2parental protein120.0301216.205DUF2897 (PF11446, IPR021550): Protein of unknown function (DUF2897)
AAA_33 (PF13671): AAA domain
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
3 ABI3BPinteractor21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
4 ANXA1suppressor80.38139.107Annexin (PF00191, IPR018502, SM00335): Annexin
5 ANXA11interactor70.6196.573Annexin (PF00191, IPR018502, SM00335): Annexin
6 ARHGEF16interactor21.0000PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
7 ARL15interactor21.0000Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
8 ASB18interactor21.0000Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
9 ATP5Hinteractor100Mt_ATP-synt_D (PF05873, IPR008689): ATP synthase D chain, mitochondrial (ATP5H)
10 ATP6V0A1interactor30.6670.567V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
11 ATP6V1B2interactor70.4299.108ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
12 AURKBinteractor90.5717.587Pkinase (PF00069, IPR000719): Protein kinase domain
13 BABAM1interactor40.6672.667VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
14 BICC1interactor100SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
KH_1 (PF00013, IPR004088, SM00322): KH domain
15 BOLLinteractor21.0000NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
16 BREoncoprotein40.6671.883BRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE)
17 C14orf1interactor30.6670.667Erg28 (PF03694, IPR005352): Erg28 like protein
18 CAND1interactor230.532126.339Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
19 CEP126interactor30.6670.500Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
K1377 (PF15352, IPR028257): Susceptibility to monomelic amyotrophy
20 CEP55interactor100.50012.233DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
ZapB (PF06005, IPR009252): Cell division protein ZapB
EABR (PF12180, IPR022008): TSG101 and ALIX binding domain of CEP55
zf-C2H2_3 (PF13878, IPR028005): zinc-finger of acetyl-transferase ESCO
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
21 CFTRsuppressor70.3337.352ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
22 CGRRF1interactor100zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
23 CHMP1Aprotein found in more fusions60.7003.161Snf7 (PF03357, IPR005024): Snf7
24 CHMP1Binteractor70.6673.167Snf7 (PF03357, IPR005024): Snf7
25 CHMP2Ainteractor70.4677.167Snf7 (PF03357, IPR005024): Snf7
26 CHMP3interactor60.7002.606Snf7 (PF03357, IPR005024): Snf7
27 CHMP4Ainteractor70.46757.929Snf7 (PF03357, IPR005024): Snf7
28 CHMP4Binteractor150.27559.656Snf7 (PF03357, IPR005024): Snf7
29 CHMP5interactor80.42910.970Snf7 (PF03357, IPR005024): Snf7
30 CLINT1protein found in more fusions70.4676.376ENTH (PF01417, IPR001026, SM00273): ENTH domain
31 CLTAinteractor50.7002.114Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain
32 COPS5protein found in more fusions280.450222.408JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
33 COPS6interactor190.68622.374DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
34 CRMP1protein found in more fusions60.6005.254Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
35 CSTF2interactor70.33314.360RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
36 CUL1suppressor240.478107.327Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
37 CUL2suppressor180.64128.093Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
38 CUL3protein found in more fusions370.297648.837Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
39 CUL4Aprotein found in more fusions210.59540.824Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
40 CUL4Boncoprotein200.65854.361Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
41 CUL5suppressor240.51881.652Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
42 CUL7protein found in more fusions170.192134.031ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
43 DCUN1D1interactor190.64929.291Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
44 DGCR8interactor60.60035.666dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
WW (PF00397, IPR001202, SM00456): WW domain
45 DPM3interactor100DPM3 (PF08285, IPR013174): Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)
46 DSG4interactor100Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
47 DUSP14interactor100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
48 EHBP1L1interactor100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
NT-C2 (PF10358, IPR019448): N-terminal C2 in EEIG1 and EHBP1 proteins
DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585)
49 EIF1AXoncoprotein100eIF-1a (PF01176, IPR006196): Translation initiation factor 1A / IF-1
50 ERGIC1interactor40.50040.522COPIIcoated_ERV (PF07970, IPR012936): Endoplasmic reticulum vesicle transporter
ERGIC_N (PF13850): Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
51 EWSR1oncoprotein330.272425.116RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
52 FBXL6interactor100LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
53 FBXO11oncoprotein50.7001.417TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
F-box-like (PF12937, IPR001810): F-box-like
Beta_helix (PF13229): Right handed beta helix region
54 FEN1oncoprotein31.00005_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
55 FLOT2interactor50.4005.738YjbH (PF06082, IPR010344): Exopolysaccharide biosynthesis protein YbjH
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
Flot (PF15975, IPR031905): Flotillin
56 GBP2interactor100GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain
GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
57 GPRASP1interactor100Arm_2 (PF04826, IPR006911): Armadillo-like
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
58 GRB2oncoprotein150.319237.219SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
59 HEPHL1interactor100Cu-oxidase_2 (PF07731, IPR011706): Multicopper oxidase
Cu-oxidase_3 (PF07732, IPR011707): Multicopper oxidase
60 HIST1H2AGinteractor90.8331.056Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
61 HNRNPCL1interactor80.9290.261FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
XhlA (PF10779, IPR019715): Haemolysin XhlA
62 HNRNPFinteractor160.7587.630RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
63 HOXA1interactor50.167214.498Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
64 HSPA5oncoprotein230.515305.729HSP70 (PF00012, IPR013126): Hsp70 protein
65 IFI16suppressor80.25023.070HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
66 IGHG1oncoprotein30.6670.222C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
67 IST1interactor60.53310.781Ist1 (PF03398, IPR005061): Regulator of Vps4 activity in the MVB pathway
68 ITSN1protein found in more fusions50.6672.000C2 (PF00168, IPR000008, SM00239): C2 domain
VIT1 (PF01988, IPR008217): VIT family
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon
GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
69 KLHL13interactor70.8101.267BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
70 LGR4interactor3040.1777tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
71 LMO2oncoprotein40100.658CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
LIM (PF00412, IPR001781, SM00132): LIM domain
72 LRRC15interactor100CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
73 MAGED1protein found in more fusions60.6003.762MAGE (PF01454, IPR002190): MAGE family
74 MAPK1IP1Lprotein found in more fusions60.6003.930MISS (PF15822, IPR031653): MAPK-interacting and spindle-stabilising protein-like
75 MCM2oncoprotein230.247238.939AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
76 MITD1interactor40.8330.667MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
MIT_C (PF16565, IPR032341): Phospholipase D-like domain at C-terminus of MIT
77 MTUS2suppressor50.333105.606DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496)
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
FAM184 (PF15665): Family with sequence similarity 184, A and B
78 MYOTinteractor200I-set (PF07679, IPR013098): Immunoglobulin I-set domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
79 NAA38interactor100LSM (PF01423, IPR001163): LSM domain
80 NAT10interactor80.5008.224DUF1726 (PF08351, IPR013562): Domain of unknown function (DUF1726)
Helicase_RecD (PF05127, IPR007807): Helicase
GNAT_acetyltr_2 (PF13718, IPR000182): GNAT acetyltransferase 2
tRNA_bind_2 (PF13725, IPR027992): Possible tRNA binding domain
81 NCOA4suppressor100ARA70 (PF12489, IPR022174): Nuclear coactivator
82 NEDD8interactor180.71343.531ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
83 NEPROinteractor100DUF4477 (PF14780, IPR027951): Domain of unknown function (DUF4477)
84 NIPBLoncoprotein31.0000DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Zip (PF02535, IPR003689): ZIP Zinc transporter
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
Cohesin_HEAT (PF12765, IPR026003): HEAT repeat associated with sister chromatid cohesion
Nipped-B_C (PF12830, IPR024986): Sister chromatid cohesion C-terminus
HEAT_2 (PF13646): HEAT repeats
DNA_repr_REX1B (PF14966): DNA repair REX1-B
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
T3SS_basalb_I (PF17001, IPR012670): Type III secretion basal body protein I, YscI, HrpB, PscI
85 NTRK1oncoprotein380.227579.439I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
86 PALM2-AKAP2interactor100DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
87 PDCD6IPinteractor130.36442.922BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
88 PEF1interactor60.7332.692EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
89 PHF20oncoprotein100GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3776 (PF12618, IPR022255): Protein of unknown function (DUF3776)
90 PIN1suppressor100.24469.339Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
91 PKP1interactor21.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
92 PLBD2interactor100Phospholip_B (PF04916, IPR007000): Phospholipase B
DUF3693 (PF12472, IPR021096): Phage related protein
93 PLSCR1interactor50.400194.707Scramblase (PF03803, IPR005552): Scramblase
94 PPIAinteractor140.297762.487Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
95 PPIHinteractor40.66751.338Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
96 PPP1CAsuppressor90.41725.471Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
97 PRG2interactor100Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
98 PRMT6interactor21.0000Methyltransf_25 (PF13649): Methyltransferase domain
99 PRPF4interactor90.357312.106PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
100 RAD21oncoprotein80.5368.877Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
101 RARSinteractor60.8000.969Arg_tRNA_synt_N (PF03485, IPR005148, SM01016): Arginyl tRNA synthetase N terminal domain
DALR_1 (PF05746, IPR008909, SM00836): DALR anticodon binding domain
DivIC (PF04977, IPR007060): Septum formation initiator
tRNA-synt_1d (PF00750, IPR015945): tRNA synthetases class I (R)
Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region
102 RBPMSprotein found in more fusions80.238221.327RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
103 RCL1interactor21.0000RTC (PF01137, IPR023797): RNA 3'-terminal phosphate cyclase
104 RIPPLY2interactor100Ripply (PF14998, IPR028127): Transcription Regulator
105 RPL10Ainteractor120.62123.023Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
106 RPL4interactor150.75212.892Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
107 S100A3interactor31.0000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
108 S100A7oncoprotein60.7332.643S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
109 SCLYinteractor21.0000Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V
110 SEC13interactor70.5334.712WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
111 SEC24Ainteractor60.5335.311Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
112 SEC31Ainteractor60.4677.764P3A (PF08727, IPR014838): Poliovirus 3A protein like
SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1)
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
113 SELENBP1suppressor100SBP56 (PF05694, IPR008826): 56kDa selenium binding protein (SBP56)
114 SNX3interactor40.50032.549PX (PF00787, IPR001683, SM00312): PX domain
115 SPG21interactor100Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
116 SPINK5interactor100Fer2 (PF00111, IPR001041): 2Fe-2S iron-sulfur cluster binding domain
Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain
PIN_5 (PF08745, IPR022785): PINc domain ribonuclease
CTU2 (PF10288, IPR019407): Cytoplasmic tRNA 2-thiolation protein 2
Kazal_2 (PF07648, IPR002350, SM00280): Kazal-type serine protease inhibitor domain
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
117 STAT5Boncoprotein31.0000SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
118 TMEM17interactor60.3338.167Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
119 TMPRSS5interactor100Trypsin (PF00089, IPR001254, SM00020): Trypsin
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
120 TOP1MTinteractor100Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
121 TOP2Aoncoprotein80.42910.310DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Toprim (PF01751, IPR006171, SM00493): Toprim domain
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
122 TRAF3oncoprotein31.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
Spc29 (PF17082, IPR031392): Spindle Pole Component 29
123 TRIM25protein found in more fusions70.3338.437Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
124 TRIM68interactor100GAGA (PF09237, IPR015318): GAGA factor
SPRY (PF00622, IPR003877, SM00449): SPRY domain
DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
125 TSG101suppressor110.42220.836APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
126 UMAD1interactor100DUF2464 (PF10240, IPR018798): Multivesicular body subunit 12
127 UNKinteractor100.31120.143MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
128 URB1interactor40.333239.695Npa1 (PF11707, IPR021714): Ribosome 60S biogenesis N-terminal
NopRA1 (PF16201, IPR032436): Nucleolar pre-ribosomal-associated protein 1
129 VPS37Cinteractor70.47611.902Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
130 VSIG8interactor21.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
131 WNT4interactor2040.041MEF2_binding (PF09047, IPR015134): MEF2 binding
wnt (PF00110, IPR005817, SM00097): wnt family

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