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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CHP1, PCAT7 (from a repository: Thu May 18 01:07:07 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins2 (14.29 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)19 (20.88 %)
The number (and %) of affected PPIs12 (63.16 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI2.429
Assortativity coefficient-0.5710
The network average Clustering coefficient0.367
The number (and %) of a zero Clustering coefficients7 (50.00 %)
The number (and %) of a zero Betweenness Centrality11 (78.57 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CHP1,PCAT7 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CHP1parental protein120.076115.000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
2 PCAT7interactor000NA
3 ELAVL1oncoprotein60.4006.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
4 MOV10interactor100AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
5 NXF1interactor31.0000NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
6 PRSS23interactor21.0000Trypsin (PF00089, IPR001254, SM00020): Trypsin
7 SHMT2interactor100SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
8 SLC9A1interactor100DUF1427 (PF07235, IPR009872): Protein of unknown function (DUF1427)
LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
9 SLC9A2oncoprotein100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
10 SLC9A3interactor100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
11 SLC9A4interactor100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
12 SLC9A5interactor21.0000Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
13 TMEM216interactor21.0000Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
14 XPO1interactor30.6671.000CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

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