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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)237
The number (and %) of the onco-proteins57 (24.05 %)
The number (and %) of the tumor suppressors21 (8.86 %)
Total number of binary PPIs (saturation %)1317 (4.71 %)
The number (and %) of affected PPIs236 (17.92 %)
The number of possible different fusions32
PPI diameter2
PPI radiusinf
The average degree of PPI10.650
Assortativity coefficient-0.2811
The network average Clustering coefficient0.525
The number (and %) of a zero Clustering coefficients15 (6.33 %)
The number (and %) of a zero Betweenness Centrality44 (18.57 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LOC100130987,ABCE1 All fusions
Proteins found in more fusions TSN (see 1 fusions); STAU1 (see 2 fusions); MAPK1 (see 2 fusions); DCXR (see 2 fusions); DDX18/DKC1 (see 1 fusions); CUL3 (see 1 fusions); PSMB3 (see 1 fusions); S100A10 (see 1 fusions); HEXB (see 1 fusions); FYN (see 1 fusions); PARK2 (see 1 fusions); YWHAH (see 2 fusions); EWSR1 (see 1 fusions); MAPRE1 (see 1 fusions); IMMT (see 4 fusions); MYO6 (see 3 fusions); STRAP (see 1 fusions); MSN (see 1 fusions); TP53 (see 3 fusions); NDUFAF4 (see 1 fusions); CBX5 (see 1 fusions); ILK (see 2 fusions); LMNA (see 4 fusions); CUL4A (see 4 fusions); LYN (see 2 fusions); PFKL (see 2 fusions); GNAZ (see 1 fusions); MAPRE1/ABLIM1 (see 1 fusions); MCM2 (see 1 fusions); DKC1 (see 2 fusions); VIM (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LOC100130987interactor000NA
2 ABCE1parental protein2360.03739561.911ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 AARSinteractor90.44411.685DHHA1 (PF02272, IPR003156): DHHA1 domain
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
4 ABCF1interactor110.49112.874ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
KOG2701 (PF09762, IPR019159): Coiled-coil domain-containing protein (DUF2037)
ABC_tran_Xtn (PF12848, IPR032781): ABC transporter
AAA_18 (PF13238): AAA domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
5 ABLIM1protein found in more fusions80.4299.023LIM (PF00412, IPR001781, SM00132): LIM domain
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
6 ACAT1interactor110.42211.428Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
7 AIF1Linteractor100EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
8 AIFM1oncoprotein90.3899.358Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
AIF-MLS (PF14962, IPR032773): Mitochondria Localisation Sequence
9 AK2interactor60.6003.833ADK (PF00406, IPR000850): Adenylate kinase
AAA_33 (PF13671): AAA domain
10 ANK2interactor40.6670.574Death (PF00531, IPR000488, SM00005): Death domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
11 AP1B1interactor90.41713.540Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
12 APEX1interactor60.5333.907Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
13 ARPC5interactor30.6670.667P16-Arc (PF04699, IPR006789): ARP2/3 complex 16 kDa subunit (p16-Arc)
14 ASNSoncoprotein70.5244.953Asn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
15 ATP6V1Ainteractor110.49115.610ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
16 ATXN10interactor40.5002.167RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
17 ATXN2Linteractor50.5000.370LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
18 C14orf166interactor60.7331.483RLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein
19 C16orf96interactor100Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
DUF2730 (PF10805, IPR020269): Protein of unknown function (DUF2730)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
DUF4795 (PF16043, IPR032013): Domain of unknown function (DUF4795)
20 C2orf47interactor90.39314.333Tim44 (PF04280, IPR007379, SM00978): Tim44-like domain
21 CACNA2D1interactor21.0000dCache_1 (PF02743, IPR004010): Cache domain
VGCC_alpha2 (PF08473, IPR013680): Neuronal voltage-dependent calcium channel alpha 2acd
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VWA_N (PF08399, IPR013608): VWA N-terminal
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
22 CBR3interactor30.6670.667adh_short (PF00106, IPR002198): short chain dehydrogenase
23 CBX3interactor90.2869.959Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
24 CBX5suppressor60.4003.733Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
25 CCNYinteractor100Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
26 CD44suppressor80.42911.619VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit
Xlink (PF00193, IPR000538, SM00445): Extracellular link domain
S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
27 CD59interactor31.0000UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
FAM163 (PF15069, IPR029379): FAM163 family
28 CENPJinteractor60.3338.333DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein
Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
AAA_23 (PF13476): AAA domain
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
29 CIAO1interactor40.8330.333WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
30 CISD1interactor80.6075.382zf-CDGSH (PF09360, IPR018967, SM00704): Iron-binding zinc finger CDGSH type
MitoNEET_N (PF10660, IPR019610): Iron-containing outer mitochondrial membrane protein N-terminus
31 CNIH4interactor100Cornichon (PF03311, IPR003377): Cornichon protein
32 CORO1Concoprotein90.52812.650DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
33 CPSF3interactor30.6670.045Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily
RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF73-100_C (PF11718, IPR021718, SM01098): Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
34 CPVLinteractor21.0000Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
35 CSTBoncoprotein40.6670.483Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
36 CTSAinteractor31.0000Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
37 CUL3protein found in more fusions710.0991498.484Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
38 CUL4Aprotein found in more fusions140.32130.185Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
39 DCP2interactor31.0000DCP2 (PF05026, IPR007722, SM01125): Dcp2, box A domain
NUDIX (PF00293, IPR000086): NUDIX domain
40 DCXRprotein found in more fusions200adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
41 DDX18protein found in more fusions110.45513.206DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF4217 (PF13959, IPR025313, SM01178): Domain of unknown function (DUF4217)
42 DDX46interactor70.6192.798CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
CdAMP_rec (PF06153, IPR010375): Cyclic-di-AMP receptor
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FAM176 (PF14851): FAM176 family
43 DIABLOsuppressor31.0000Smac_DIABLO (PF09057, IPR015142): Second Mitochondria-derived Activator of Caspases
44 DKC1oncoprotein100.5008.356DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain
PUA (PF01472, IPR002478, SM00359): PUA domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
45 DNAJC7interactor70.4762.122DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_17 (PF13431): Tetratricopeptide repeat
46 DSG2oncoprotein60.5335.400BAT2_N (PF07001, IPR009738): BAT2 N-terminus
Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
47 DUTinteractor50.6002.150dUTPase (PF00692, IPR008180): dUTPase
48 DYNLL1interactor90.35714.300Dynein_light (PF01221, IPR001372): Dynein light chain type 1
49 EBPinteractor100Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
EBP (PF05241, IPR007905): Emopamil binding protein
50 EIF3Dinteractor120.51511.876eIF-3_zeta (PF05091, IPR007783): Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
51 EIF3Fsuppressor120.40917.344JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
52 EIF3Hinteractor80.5368.172Androgen_recep (PF02166, IPR001103): Androgen receptor
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
NHS (PF15273, IPR024845): NHS-like
53 EIF4A3interactor230.33885.369DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
54 EPB41suppressor50.6002.9004_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
SAB (PF04382, IPR007477): SAB domain
55 EPB41L2interactor50.8000.9004_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DUF966 (PF06136, IPR010369): Domain of unknown function (DUF966)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
SAB (PF04382, IPR007477): SAB domain
TCP (PF03634, IPR005333): TCP family transcription factor
56 EPB41L3suppressor110.38220.4344_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SAB (PF04382, IPR007477): SAB domain
57 ETF1interactor50.5005.000eRF1_1 (PF03463, IPR005140): eRF1 domain 1
eRF1_2 (PF03464, IPR005141): eRF1 domain 2
eRF1_3 (PF03465, IPR005142): eRF1 domain 3
58 EWSR1oncoprotein320.204260.406RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
59 EXOSC4interactor90.32114.207RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
60 FAM96Binteractor70.4768.056DUF59 (PF01883, IPR002744): Domain of unknown function DUF59
61 FANCIinteractor70.5244.952DUF3972 (PF13118, IPR025002): Protein of unknown function (DUF3972)
FANCI_S1-cap (PF14674, IPR029305): FANCI solenoid 1 cap
FANCI_S1 (PF14675, IPR029308): FANCI solenoid 1
FANCI_S2 (PF14676, IPR026171): FANCI solenoid 2
FANCI_S3 (PF14677, IPR029313): FANCI solenoid 3
FANCI_S4 (PF14678, IPR029314): FANCI solenoid 4
FANCI_HD1 (PF14679, IPR029310): FANCI helical domain 1
FANCI_HD2 (PF14680, IPR029312): FANCI helical domain 2
62 FBLinteractor150.53312.396Fibrillarin (PF01269, IPR000692): Fibrillarin
63 FBXO6interactor400.092531.687FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
64 FDPSinteractor31.0000polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase
65 FLNAsuppressor320.226257.951CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
66 FLNBoncoprotein120.40922.516CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
67 FLOT1interactor90.30618.034CrtC (PF07143, IPR010791): CrtC N-terminal lipocalin domain
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
Flot (PF15975, IPR031905): Flotillin
68 FLOT2interactor70.4768.333YjbH (PF06082, IPR010344): Exopolysaccharide biosynthesis protein YbjH
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
Flot (PF15975, IPR031905): Flotillin
69 FUBP3interactor60.4670.649DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
70 FYNoncoprotein60.5003.500Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
71 GADD45GIP1suppressor21.0000CR6_interact (PF10147, IPR018472): Growth arrest and DNA-damage-inducible proteins-interacting protein 1
72 GAS2L3interactor21.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
73 GLB1oncoprotein31.0000Glyco_hydro_35 (PF01301, IPR001944): Glycosyl hydrolases family 35
BetaGal_dom4_5 (PF13364, IPR025300): Beta-galactosidase jelly roll domain
74 GNA11oncoprotein30.6670.333G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
75 GNAQoncoprotein40.5001.233G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
76 GNAZprotein found in more fusions200G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
77 GNB1interactor90.25020.700Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
78 GNB4interactor70.2869.917Spore_YhcN_YlaJ (PF09580, IPR019076): Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
79 GNG5interactor30.6670.333G-gamma (PF00631, IPR015898, SM00224): GGL domain
80 GNSinteractor21.0000Sulfatase (PF00884, IPR000917): Sulfatase
DUF4976 (PF16347, IPR032506): Domain of unknown function (DUF4976)
81 GSPT1oncoprotein40.8330.667GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
82 H3F3Concoprotein100Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
83 HAX1interactor110.43618.137Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
84 HEXBprotein found in more fusions31.0000Glyco_hydro_20 (PF00728, IPR015883): Glycosyl hydrolase family 20, catalytic domain
Glyco_hydro_20b (PF02838, IPR015882): Glycosyl hydrolase family 20, domain 2
Glycohydro_20b2 (PF14845, IPR029019): beta-acetyl hexosaminidase like
85 HIST1H1Concoprotein90.4177.404Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
86 HIST2H2BFinteractor31.0000Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
87 HM13interactor30.6670.667Peptidase_A22B (PF04258, IPR007369): Signal peptide peptidase
DUF4345 (PF14248, IPR025597): Domain of unknown function (DUF4345)
88 HMGB1P1interactor100NA
89 HSPE1interactor80.4649.652Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
90 IGF2Rsuppressor80.35714.000ATG27 (PF09451, IPR018939): Autophagy-related protein 27
CIMR (PF00878, IPR000479): Cation-independent mannose-6-phosphate receptor repeat
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
91 ILKsuppressor190.24868.418Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
92 IMMTprotein found in more fusions110.48911.162Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
93 IQGAP1interactor240.290110.015CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
94 ISYNA1interactor30.6670.250NAD_binding_5 (PF07994, IPR002587): Myo-inositol-1-phosphate synthase
95 ITGA4interactor420.130436.244FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
96 JUPsuppressor110.36422.765Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
97 KARSinteractor100.40011.634tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
98 KIAA1524oncoprotein31.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ParcG (PF10274, IPR019399): Parkin co-regulated protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
99 KIF5Binteractor100.40016.545ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
100 LMNAprotein found in more fusions210.32162.935Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
101 LMNB1interactor100.5785.720Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
102 LMNB2interactor70.5243.193Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
103 LYNoncoprotein70.4675.741Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
104 MACF1oncoprotein70.3816.951ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
CTV_P33 (PF07184, IPR010803): Citrus tristeza virus P33 protein
DnaI_N (PF07319, IPR009928): Primosomal protein DnaI N-terminus
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF19 (PF01579, IPR002542): Domain of unknown function (DUF19)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Peptidase_S49 (PF01343, IPR002142): Peptidase family S49
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
SYF2 (PF08231, IPR013260): SYF2 splicing factor
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
DUF3813 (PF12758, IPR024217): Protein of unknown function (DUF3813)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
TEX12 (PF15219, IPR029193): Testis-expressed 12
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
105 MAP1Binteractor50.7000.294DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
MAP1B_neuraxin (PF00414, IPR000102): Neuraxin and MAP1B repeat
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
Striatin (PF08232, IPR013258): Striatin family
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
106 MAP4oncoprotein50.5001.448SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
107 MAPK1oncoprotein120.36421.679Pkinase (PF00069, IPR000719): Protein kinase domain
108 MAPRE1oncoprotein160.23859.513CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
109 MCM2oncoprotein570.114974.007AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
110 MDN1interactor21.0000AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
DnaB_C (PF03796, IPR007694): DnaB-like helicase C terminal domain
AAA_16 (PF13191): AAA ATPase domain
Sigma54_activ_2 (PF14532, IPR002078): Sigma-54 interaction domain
111 MED23interactor70.5246.667Med23 (PF11573, IPR021629): Mediator complex subunit 23
112 MFGE8interactor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
113 MMS19interactor150.32452.757DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
114 MSNoncoprotein140.32133.189DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
115 MYO6protein found in more fusions80.4763.935BUD22 (PF09073, IPR015158): BUD22
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Rad9 (PF04139, IPR007268): Rad9
Sec62 (PF03839, IPR004728): Translocation protein Sec62
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain
116 NAA10oncoprotein30.6670.500Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
117 NAT10interactor90.5562.539DUF1726 (PF08351, IPR013562): Domain of unknown function (DUF1726)
Helicase_RecD (PF05127, IPR007807): Helicase
GNAT_acetyltr_2 (PF13718, IPR000182): GNAT acetyltransferase 2
tRNA_bind_2 (PF13725, IPR027992): Possible tRNA binding domain
118 NDUFA13interactor60.5335.167GRIM-19 (PF06212, IPR009346): GRIM-19 protein
119 NDUFA4interactor140.26946.060B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
120 NDUFA5interactor80.5008.967ETC_C1_NDUFA5 (PF04716, IPR006806): ETC complex I subunit conserved region
121 NDUFAF4protein found in more fusions50.8330.500UPF0240 (PF06784, IPR009622): Uncharacterised protein family (UPF0240)
122 NTRK1oncoprotein1130.0664446.426I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
123 NUMA1oncoprotein120.31828.717Colicin (PF01024, IPR000293): Colicin pore forming domain
Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
124 ORAOV1oncoprotein30.6670.333Yae1_N (PF09811, IPR019191): Essential protein Yae1, N terminal
125 PAK3interactor200PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
126 PARK2suppressor290.193191.281IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
127 PDHA1interactor70.5242.520E1_dh (PF00676, IPR001017): Dehydrogenase E1 component
128 PDIA3interactor80.5366.715Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
129 PEBP1suppressor40.5002.167PBP (PF01161, IPR008914): Phosphatidylethanolamine-binding protein
130 PEG10oncoprotein21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Retrotrans_gag (PF03732, IPR005162): Retrotransposon gag protein
Asp_protease_2 (PF13650): Aspartyl protease
zf-CCHC_5 (PF14787): GAG-polyprotein viral zinc-finger
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
PRIMA1 (PF16101): Proline-rich membrane anchor 1
DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
131 PFDN2interactor50.7000.944Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
132 PFKLprotein found in more fusions70.4001.226PFK (PF00365, IPR000023): Phosphofructokinase
133 PNPinteractor60.6000.454PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily
134 POC5interactor50.6002.333vATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
135 POLR1Binteractor40.8330.667RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain
RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
136 PPM1Ginteractor60.8670.268Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
PP2C (PF00481, IPR001932): Protein phosphatase 2C
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
137 PPP1CBinteractor170.36052.142Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
138 PPP1CConcoprotein160.35848.110Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
139 PPP2R2Ainteractor50.8000.194WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
140 PPP6Cinteractor70.5711.994Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
141 PRCPinteractor21.0000Peptidase_S28 (PF05577, IPR008758): Serine carboxypeptidase S28
142 PRKACAinteractor110.27328.356Pkinase (PF00069, IPR000719): Protein kinase domain
143 PRKAR2Ainteractor50.7001.500RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
144 PSIP1oncoprotein60.4673.650AT_hook (PF02178, IPR017956, SM00384): AT hook motif
BEX (PF04538, IPR021156): Brain expressed X-linked like family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
PWWP (PF00855, IPR000313, SM00293): PWWP domain
LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF)
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
145 PSMA2interactor160.61919.075Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
146 PSMA5oncoprotein160.60021.557Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
147 PSMB3protein found in more fusions150.59316.190Proteasome (PF00227, IPR001353): Proteasome subunit
148 PSMC2interactor180.52228.469AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
149 PSMD1interactor150.66712.222PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
150 PSMD13interactor120.8483.939Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase
PCI (PF01399, IPR000717, SM00088): PCI domain
151 PSMD14interactor120.8189.087JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
152 PSMD4interactor150.58123.705UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
153 PSMD8interactor130.7567.393CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
154 PTERinteractor31.0000PTE (PF02126, IPR001559): Phosphotriesterase family
155 PTGES3interactor90.3578.412CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
156 PTPRFinteractor40.8330.500Arylsulfotrans (PF05935, IPR010262): Arylsulfotransferase (ASST)
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
DUF3377 (PF11857, IPR021805): Domain of unknown function (DUF3377)
157 RAB35oncoprotein30.6670.667Ras (PF00071, IPR001806, SM00173): Ras family
158 RALAoncoprotein40.8330.250ArgK (PF03308, IPR005129): ArgK protein
Ras (PF00071, IPR001806, SM00173): Ras family
ThiF (PF00899, IPR000594): ThiF family
159 RAP2Boncoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
160 RAVER1interactor50.5002.100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
161 RBBP7suppressor90.33314.255WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
162 RFC4interactor80.5365.645AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Rad17 (PF03215): Rad17 cell cycle checkpoint protein
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
163 RNASELsuppressor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
Ribonuc_2-5A (PF06479, IPR010513): Ribonuclease 2-5A
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
164 RNF2interactor480.119539.968zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
165 RP2interactor100NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
TBCC (PF07986, IPR012945): Tubulin binding cofactor C
166 RPL21interactor210.48139.674Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
167 RPL32interactor90.7223.080Ribosomal_L32e (PF01655, IPR001515): Ribosomal protein L32
168 RPL35Ainteractor130.7318.372Ribosomal_L35Ae (PF01247, IPR001780): Ribosomal protein L35Ae
169 RPL36interactor130.6678.846Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
170 RPL4interactor250.43361.638Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
171 RPL7interactor220.51137.977Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
172 RPRD1Binteractor40.6671.167CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
173 RPS12interactor180.51634.005Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
174 RPS25interactor180.58218.748Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
175 RPS27interactor120.7733.756Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
176 RPS29interactor70.7623.167Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e
177 RPS3Ainteractor220.50641.433Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
178 RRP12interactor50.5000.317NUC173 (PF08161, IPR012978): NUC173 domain
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
PPP4R2 (PF09184, IPR015267): PPP4R2
Ribosomal_L37 (PF08561, IPR013870): Mitochondrial ribosomal protein L37
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
179 RRP1Binteractor90.5007.244Nop52 (PF05997, IPR010301): Nucleolar protein,Nop52
180 S100A10oncoprotein50.6671.667S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
181 SAE1interactor50.7001.900ThiF (PF00899, IPR000594): ThiF family
182 SAFBsuppressor100.48912.619RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
183 SDF4interactor40.8330.500Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
184 SDHBsuppressor90.44410.822Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain
Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain
Fer4_17 (PF13534): 4Fe-4S dicluster domain
185 SF3A1interactor140.42926.551TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
186 SFXN4interactor31.0000Mtc (PF03820, IPR004686): Tricarboxylate carrier
187 SIRT7interactor580.093927.275DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
188 SLC25A4interactor50.5002.400Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
189 SMARCA5interactor100.5008.122HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DBINO (PF13892, IPR020838): DNA-binding domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
190 SMC1Aoncoprotein120.45514.521SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
191 SMC4interactor60.5330.960SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
192 SNAP23interactor50.5002.167DivIC (PF04977, IPR007060): Septum formation initiator
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
SNAP-25 (PF00835, IPR000928): SNAP-25 family
DUF5089 (PF17002, IPR031547): Domain of unknown function (DUF5089)
193 SNRPFinteractor50.6001.100LSM (PF01423, IPR001163): LSM domain
194 SRConcoprotein90.6076.741Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
195 SRMinteractor40.5001.233Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase
196 SRP9interactor50.5003.952SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
197 SRRM2interactor170.36838.543cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
198 SSFA2interactor50.8000.583KRAP_IP3R_bind (PF14722, IPR029325): Ki-ras-induced actin-interacting protein-IP3R-interacting domain
SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
199 STARD9interactor21.0000START (PF01852, IPR002913, SM00234): START domain
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
200 STAU1protein found in more fusions230.36464.630dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
201 STRAPprotein found in more fusions50.6670.327WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
202 SUCLG2interactor31.0000ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain
Ligase_CoA (PF00549, IPR005811): CoA-ligase
203 SUPT16Hinteractor90.6793.264Nop14 (PF04147, IPR007276): Nop14-like family
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
FACT-Spt16_Nlob (PF14826, IPR029148): FACT complex subunit SPT16 N-terminal lobe domain
204 SURF4interactor40.5001.667SURF4 (PF02077, IPR002995): SURF4 family
205 TBCDinteractor50.7002.333HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
HEAT_EZ (PF13513): HEAT-like repeat
206 TCEB1oncoprotein50.5003.733Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
207 TECRinteractor80.5714.935Steroid_dh (PF02544, IPR001104): 3-oxo-5-alpha-steroid 4-dehydrogenase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
208 TFAMinteractor21.0000HMG_box_2 (PF09011, IPR009071): HMG-box domain
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
209 TIMM21interactor31.0000TIM21 (PF08294, IPR013261): TIM21
210 TIMM23interactor50.4003.700Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
211 TMEM17interactor110.20036.300Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
212 TMEM216interactor70.33311.333Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
213 TMPOinteractor90.50010.182LEM (PF03020, IPR003887, SM00540): LEM domain
Thymopoietin (PF08198, IPR013146): Thymopoietin protein
LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
214 TOMM20interactor100RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
215 TP53suppressor400.155394.441DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
216 TPP1interactor40.5000.822Peptidase_S8 (PF00082, IPR000209): Subtilase family
Pro-kuma_activ (PF09286, IPR015366, SM00944): Pro-kumamolisin, activation domain
217 TSNprotein found in more fusions50.5002.500Translin (PF01997, IPR002848): Translin family
218 TTC29interactor21.0000DUF1266 (PF06889, IPR009677): Protein of unknown function (DUF1266)
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2225 (PF09986, IPR018708): Uncharacterized protein conserved in bacteria (DUF2225)
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_20 (PF14561): Tetratricopeptide repeat
219 TTC37interactor60.6671.945DUF982 (PF06169, IPR010385): Protein of unknown function (DUF982)
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_3 (PF07720, IPR011716): Tetratricopeptide repeat
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_15 (PF13429): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
Retrotran_gag_2 (PF14223): gag-polypeptide of LTR copia-type
TPR_19 (PF14559): Tetratricopeptide repeat
220 TWF1interactor60.8001.300Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
221 UBASH3Ainteractor41.0000His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Ste5 (PF11610, IPR021651): Scaffold protein Ste5, Fus3-binding region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
222 UFL1suppressor21.0000CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
Helicase_RecD (PF05127, IPR007807): Helicase
DUF2042 (PF09743, IPR018611): Uncharacterized conserved protein (DUF2042)
UBN_AB (PF14075, IPR026947): Ubinuclein conserved middle domain
IL31 (PF15209, IPR027987): Interleukin 31
223 ULBP3interactor100Gag_p6 (PF08705, IPR014817): Gag protein p6
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
224 USP50interactor21.0000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
225 USP7oncoprotein220.28692.998MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
226 VAPAinteractor200.242113.830DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
227 VAPBinteractor60.6672.786ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
ZapB (PF06005, IPR009252): Cell division protein ZapB
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
228 VDAC2interactor130.44925.430Porin_3 (PF01459, IPR027246): Eukaryotic porin
229 VDAC3interactor130.46222.643Porin_3 (PF01459, IPR027246): Eukaryotic porin
230 VIMsuppressor230.27389.123Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
231 WDR1interactor120.42420.075eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
232 WDR77oncoprotein130.36426.520LT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
233 XPO1interactor380.175400.881CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
234 XRCC5suppressor160.34337.743Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
235 YAE1D1interactor70.4297.944Yae1_N (PF09811, IPR019191): Essential protein Yae1, N terminal
236 YWHAHprotein found in more fusions120.32720.86014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
237 ZNF207interactor60.6672.800MCPVI (PF02993, IPR004243): Minor capsid protein VI
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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