Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: W68688 is the fusion of parental proteins ANAPC4, RTN4 (from a repository: Tue Dec 6 14:48:22 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)60
The number (and %) of the onco-proteins23 (38.33 %)
The number (and %) of the tumor suppressors7 (11.67 %)
Total number of binary PPIs (saturation %)442 (24.97 %)
The number (and %) of affected PPIs59 (13.35 %)
The number of possible different fusions6
PPI diameter2
PPI radius1
The average degree of PPI13.867
Assortativity coefficient-0.2798
The network average Clustering coefficient0.616
The number (and %) of a zero Clustering coefficients4 (6.67 %)
The number (and %) of a zero Betweenness Centrality9 (15.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: RTN4,ANAPC4 All fusions
: W68688;
Proteins found in more fusions SH3KBP1 (see 1 fusions); TRIM33 (see 1 fusions); HUWE1 (see 2 fusions); DDB1 (see 2 fusions); WWP1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 W68688chimera590.2091414.713ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ANAPC4 (PF12896, IPR024790): Anaphase-promoting complex, cyclosome, subunit 4
2 ANAPC1suppressor320.45492.923PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
ANAPC1 (PF12859, IPR024990): Anaphase-promoting complex subunit 1
3 ANAPC10interactor190.66715.047ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
4 ANAPC11interactor130.8033.410zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
5 ANAPC13interactor90.9720.118Apc13p (PF05839, IPR008401): Apc13p protein
6 ANAPC15interactor190.70815.723Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
ANAPC15 (PF15243, IPR026182): Anaphase-promoting complex subunit 15
7 ANAPC16interactor180.66015.758DUF2110 (PF09883, IPR016757): Uncharacterized protein conserved in archaea (DUF2110)
8 ANAPC2interactor230.62823.448ANAPC2 (PF08672, IPR014786, SM01013): Anaphase promoting complex (APC) subunit 2
Cullin (PF00888, IPR001373, SM00182): Cullin family
9 ANAPC5interactor290.47863.566TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
10 ANAPC7interactor300.53053.044TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
11 ATF2oncoprotein200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
12 BUB1Boncoprotein170.70010.014Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2
Pkinase (PF00069, IPR000719): Protein kinase domain
XhlA (PF10779, IPR019715): Haemolysin XhlA
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
13 BUB3interactor100.5788.977WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
14 CCNA2oncoprotein130.5459.752Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
15 CCNB1oncoprotein110.6914.467Adeno_E1A (PF02703, IPR003853): Early E1A protein
Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
16 CDC16interactor340.440105.750Dynein_light (PF01221, IPR001372): Dynein light chain type 1
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
17 CDC20oncoprotein350.412147.527WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
18 CDC23interactor340.47080.290ANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23
DUF772 (PF05598, IPR008490): Transposase domain (DUF772)
Menin (PF05053, IPR007747): Menin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
19 CDC26interactor190.66715.338ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
20 CDC27oncoprotein420.360212.908TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
21 CDK1oncoprotein110.4449.596Pkinase (PF00069, IPR000719): Protein kinase domain
22 CFAP97interactor110.8731.490DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
KIAA1430 (PF13879, IPR029488): KIAA1430 homologue
GH97_C (PF14509, IPR029483): Glycosyl-hydrolase 97 C-terminal, oligomerisation
23 CIRBPoncoprotein31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
24 COPS2suppressor50.7001.667YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
25 DCPSinteractor60.8000.626DcpS (PF05652, IPR008594): Scavenger mRNA decapping enzyme (DcpS) N-terminal
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
26 DDB1protein found in more fusions110.35620.483CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
27 FBXO5oncoprotein140.8354.562IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
28 FXR2interactor31.0000Agenet (PF05641, IPR008395, SM00743): Agenet domain
REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein)
KH_1 (PF00013, IPR004088, SM00322): KH domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
29 FZR1suppressor310.426116.248WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
30 HECW2interactor100.8064.167C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
31 HUWE1oncoprotein120.43617.139BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
32 KIF18Ainteractor21.0000Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4005 (PF13178, IPR025064): Protein of unknown function (DUF4005)
33 KRASoncoprotein110.48910.955Ras (PF00071, IPR001806, SM00173): Ras family
34 LRCH4interactor100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
LRR_8 (PF13855, IPR001611): Leucine rich repeat
35 MAD2L1oncoprotein120.7274.324HORMA (PF02301, IPR003511): HORMA domain
36 MAGIXinteractor100.9560.261PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
37 MDC1suppressor150.7907.517FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
38 NANOGinteractor90.3939.356Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
39 NEK2interactor110.8221.886Pkinase (PF00069, IPR000719): Protein kinase domain
40 NTRK1oncoprotein140.34632.909I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
41 PAXIP1interactor140.61521.297BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
42 PENKinteractor70.9520.118Op_neuropeptide (PF08035, IPR013532): Opioids neuropeptide
Opiods_neuropep (PF01160, IPR006024): Vertebrate endogenous opioids neuropeptide
SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
43 PHF8interactor120.8791.793JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
PHD (PF00628, IPR019787, SM00249): PHD-finger
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
44 POU5F1oncoprotein70.4673.339Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
45 PRR13interactor200DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
46 PTENsuppressor70.6196.833DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
47 RAB33Aoncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
48 RAD21oncoprotein60.5333.789Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
49 RPA2oncoprotein90.38911.648RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
50 RRM2interactor50.8000.750Ribonuc_red_sm (PF00268, IPR000358): Ribonucleotide reductase, small chain
51 SH3KBP1protein found in more fusions71.0000Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
52 SIRT2suppressor40.8330.154SIR2 (PF02146, IPR003000): Sir2 family
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
53 SOX2oncoprotein140.55115.456HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
54 TP53BP1suppressor170.52930.74653-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
55 TRIM33oncoprotein160.65713.389PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
Spectrin (PF00435, IPR002017): Spectrin repeat
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
56 TTLL1interactor80.9640.143TTL (PF03133, IPR004344): Tubulin-tyrosine ligase family
57 UBE2Sinteractor130.9550.622ALF (PF03752, IPR005506): Short repeats of unknown function
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
58 USP37interactor180.61826.211UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37
59 WWP1oncoprotein31.0000C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
60 XPO1interactor180.45835.756CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACAA2interactorThiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
2 ANAPC4parental proteinANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ANAPC4 (PF12896, IPR024790): Anaphase-promoting complex, cyclosome, subunit 4
3 ARL6IP1interactorReticulon (PF02453, IPR003388): Reticulon
TraG_N (PF07916, IPR012931): TraG-like protein, N-terminal region
4 ARL6IP5suppressorPRA1 (PF03208, IPR004895): PRA1 family protein
RBD-FIP (PF09457, IPR019018): FIP domain
5 ATIConcoproteinAICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
6 ATL3interactorGBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain
GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
7 ATP1B1interactorNa_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
8 ATP1B3interactorNa_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
9 ATP5OinteractorOSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit
10 BAIAP2interactorIMD (PF08397, IPR013606): IRSp53/MIM homology domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
11 BCL2oncoproteinBcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
12 BCL2L1oncoproteinBcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
13 C4orf32interactorDUF4605 (PF15378, IPR027953): Domain of unknown function (DUF4605)
14 CFL1interactorCofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
15 CLN8interactorTRAM_LAG1_CLN8 (PF03798, IPR006634): TLC domain
16 CNTNAP1interactorEGF (PF00008, IPR000742, SM00181): EGF-like domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
17 COL4A3BPinteractorAcyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
PH (PF00169, IPR001849, SM00233): PH domain
START (PF01852, IPR002913, SM00234): START domain
18 CRMP1interactorAmidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
19 CYB5R3interactorFAD_binding_6 (PF00970, IPR008333): Oxidoreductase FAD-binding domain
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
20 DDX46interactorCENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
CdAMP_rec (PF06153, IPR010375): Cyclic-di-AMP receptor
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FAM176 (PF14851): FAM176 family
21 DERL1interactorDER1 (PF04511, IPR007599): Der1-like family
22 DERL2interactorDER1 (PF04511, IPR007599): Der1-like family
23 EEF1DinteractorEF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
24 EPPK1interactorDUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HupF_HypC (PF01455, IPR001109): HupF/HypC family
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal
25 FAM210BinteractorDUF1279 (PF06916, IPR009688): Protein of unknown function (DUF1279)
RepB (PF07506, IPR011111): RepB plasmid partitioning protein
26 GOLT1BinteractorGot1 (PF04178, IPR007305): Got1/Sft2-like family
27 GRHPRinteractor2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
28 HLA-DPB1interactorMHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
29 HNRNPMinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
30 HSD17B10interactoradh_short (PF00106, IPR002198): short chain dehydrogenase
31 HSDL1interactoradh_short (PF00106, IPR002198): short chain dehydrogenase
Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
32 IGFBP7suppressorIGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein
Kazal_2 (PF07648, IPR002350, SM00280): Kazal-type serine protease inhibitor domain
Ig_3 (PF13927): Immunoglobulin domain
33 ILF3oncoproteindsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
34 KCNA1interactorIon_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
35 KCNA2interactorIon_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
36 KIAA1033interactorWASH-7_mid (PF14744, IPR028282): WASH complex subunit 7
WASH-7_N (PF14745, IPR028191): WASH complex subunit 7, N-terminal
WASH-7_C (PF14746, IPR028283): WASH complex subunit 7, C-terminal
37 KTN1oncoproteinETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PTPS (PF01242, IPR007115): 6-pyruvoyl tetrahydropterin synthase
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Fimbrial_PilY2 (PF14481, IPR029497): Type 4 fimbrial biogenesis protein PilY2
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
38 LAMA4interactorDUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ZapB (PF06005, IPR009252): Cell division protein ZapB
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
Laminin_I (PF06008, IPR009254): Laminin Domain I
Laminin_II (PF06009, IPR010307): Laminin Domain II
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
39 LRPAP1interactorAlpha-2-MRAP_C (PF06401, IPR010483): Alpha-2-macroglobulin RAP, C-terminal domain
Alpha-2-MRAP_N (PF06400, IPR009066): Alpha-2-macroglobulin RAP, N-terminal domain
40 METTL7BinteractorMethyltransf_11 (PF08241, IPR013216): Methyltransferase domain
41 NAPAoncoproteinSNAP (PF14938): Soluble NSF attachment protein, SNAP
42 NR4A1suppressorzf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
43 PLEKHF2interactorFYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
PH (PF00169, IPR001849, SM00233): PH domain
44 POT1interactorPOT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
45 PRAF2interactorPRA1 (PF03208, IPR004895): PRA1 family protein
46 RPA1suppressorRep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
47 RPA3interactorRep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
48 RPS27interactorRibosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
49 RTN1interactorReticulon (PF02453, IPR003388): Reticulon
50 RTN2interactorReticulon (PF02453, IPR003388): Reticulon
51 RTN3interactorReticulon (PF02453, IPR003388): Reticulon
52 RTN4parental proteinCENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Reticulon (PF02453, IPR003388): Reticulon
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
53 RTN4IP1suppressorADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
54 S100A16interactorS_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
55 SBNO1oncoproteinHelicase_C_4 (PF13871, IPR026937): C-terminal domain on Strawberry notch homologue
AAA_34 (PF13872): P-loop containing NTP hydrolase pore-1
56 SCAMP1interactorSCAMP (PF04144, IPR007273): SCAMP family
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
57 SCAMP2interactorSCAMP (PF04144, IPR007273): SCAMP family
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
58 SGCZinteractorSarcoglycan_1 (PF04790, IPR006875): Sarcoglycan complex subunit protein
59 SH3PXD2AinteractorDUF1604 (PF07713, IPR011666): Protein of unknown function (DUF1604)
PX (PF00787, IPR001683, SM00312): PX domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
hSH3 (PF14603, IPR029294): Helically-extended SH3 domain
60 SLC25A10interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
61 SLC9A3R2interactorEBP50_C (PF09007, IPR015098): EBP50, C-terminal
GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
62 SNX1interactorPX (PF00787, IPR001683, SM00312): PX domain
Sorting_nexin (PF03700, IPR005329): Sorting nexin, N-terminal domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
63 SNX12interactorPX (PF00787, IPR001683, SM00312): PX domain
64 SNX15interactorMIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
PX (PF00787, IPR001683, SM00312): PX domain
65 SNX2interactorPX (PF00787, IPR001683, SM00312): PX domain
Sorting_nexin (PF03700, IPR005329): Sorting nexin, N-terminal domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
66 SPG21interactorAbhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
67 SPOPsuppressorBACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
MATH (PF00917, IPR002083, SM00061): MATH domain
68 SSR3interactorTRAP-gamma (PF07074, IPR009779): Translocon-associated protein, gamma subunit (TRAP-gamma)
69 SYT16interactorC2 (PF00168, IPR000008, SM00239): C2 domain
DUF3684 (PF12449, IPR022155): Protein of unknown function (DUF3684)
70 TBL2suppressoreIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
FdsD (PF11390, IPR021074): NADH-dependant formate dehydrogenase delta subunit FdsD
71 TERF1interactorTRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
72 TJP1interactorDUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal
73 TMEM216interactorTransmemb_17 (PF09799, IPR019184): Predicted membrane protein
74 TMEM43interactorTMEM43 (PF07787, IPR012430): Transmembrane protein 43
UPF0697 (PF15117, IPR029368): Uncharacterised protein family UPF0697
75 TMEM65interactorTMEM65 (PF10507, IPR019537): Transmembrane protein 65
76 TMEM70interactorTMEM70 (PF06979, IPR009724): Assembly, mitochondrial proton-transport ATP synth complex
77 UNKinteractorMbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
78 UQCRC1interactorPeptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
79 UQCRC2oncoproteinPeptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
80 VAPAinteractorDUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
81 ZFYVE21interactorFYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
ZFYVE21_C (PF16696, IPR032031): Zinc finger FYVE domain-containing protein 21 C-terminus

B a c k    t o    T o p ⇑