1 |
ABI1 | oncoprotein | Abi_HHR (PF07815, IPR012849): Abl-interactor HHR Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124) PRIMA1 (PF16101): Proline-rich membrane anchor 1 ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension | |
2 |
ABI2 | suppressor | Abi_HHR (PF07815, IPR012849): Abl-interactor HHR NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region SH3_9 (PF14604, IPR001452): Variant SH3 domain TMEM171 (PF15471, IPR029173): Transmembrane protein family 171 ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension | |
3 |
ABL1 | parental protein | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 | |
4 |
ABL2 | oncoprotein | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NHS (PF15273, IPR024845): NHS-like | |
5 |
ACTA1 | interactor | Actin (PF00022, IPR004000, SM00268): Actin | |
6 |
ANKRA2 | interactor | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) | |
7 |
AP2A1 | interactor | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain HEAT_2 (PF13646): HEAT repeats | |
8 |
AP2B1 | interactor | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain | |
9 |
ARHGAP17 | interactor | BAR (PF03114, IPR004148, SM00721): BAR domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain | |
10 |
ATM | oncoprotein | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 | |
11 |
ATR | oncoprotein | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 THP2 (PF09432, IPR018557): Tho complex subunit THP2 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat UME (PF08064, IPR012993, SM00802): UME (NUC010) domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat SgrT (PF15894, IPR031767): Inhibitor of glucose uptake transporter SgrT | |
12 |
BAG1 | oncoprotein | BAG (PF02179, IPR003103, SM00264): BAG domain Presenilin (PF01080, IPR001108): Presenilin ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) | |
13 |
BCAR1 | oncoprotein | Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) Caskin1-CID (PF16600): Caskin1 CASK-interaction domain | |
14 |
BCL2L1 | oncoprotein | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4 | |
15 |
BCR | parental protein | Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain IQ_SEC7_PH (PF16453, IPR001849): PH domain | |
16 |
BMP2K | interactor | Pkinase (PF00069, IPR000719): Protein kinase domain TCP (PF03634, IPR005333): TCP family transcription factor Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal EOS1 (PF12326, IPR021100): N-glycosylation protein BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator FAM60A (PF15396, IPR026065): Protein Family FAM60A | |
17 |
BRCA1 | oncoprotein | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT | |
18 |
CABLES2 | interactor | Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain | |
19 |
CASP9 | oncoprotein | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Peptidase_C14 (PF00656, IPR011600): Caspase domain | |
20 |
CAT | suppressor | Catalase (PF00199, IPR011614, SM01060): Catalase Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive | |
21 |
CCND2 | oncoprotein | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain | |
22 |
CDK1 | oncoprotein | Pkinase (PF00069, IPR000719): Protein kinase domain | |
23 |
CDKN1B | oncoprotein | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH | |
24 |
CDON | oncoprotein | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Glyco_hydro_76 (PF03663, IPR005198): Glycosyl hydrolase family 76 I-set (PF07679, IPR013098): Immunoglobulin I-set domain Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain | |
25 |
CKAP4 | interactor | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) | |
26 |
CREB1 | oncoprotein | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function | |
27 |
CTNNB1 | oncoprotein | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat | |
28 |
DDB1 | interactor | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term | |
29 |
DDX5 | oncoprotein | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain | |
30 |
DOK2 | suppressor | IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain | |
31 |
DRG1 | interactor | MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase TGS (PF02824, IPR004095): TGS domain MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain | |
32 |
EEF1G | interactor | EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein | |
33 |
EGFR | oncoprotein | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV | |
34 |
EIF2A | interactor | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A | |
35 |
EPHA3 | oncoprotein | EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain | |
36 |
EPHB2 | suppressor | EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain | |
37 |
ERBB2 | oncoprotein | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV | |
38 |
ERBB3 | oncoprotein | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV | |
39 |
ERBB4 | oncoprotein | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV | |
40 |
EVL | oncoprotein | VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain WH1 (PF00568, IPR000697, SM00461): WH1 domain | |
41 |
EWSR1 | oncoprotein | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head | |
42 |
FGFR1OP | oncoprotein | FOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domain | |
43 |
FOS | oncoprotein | bZIP_1 (PF00170, IPR004827): bZIP transcription factor | |
44 |
FUS | oncoprotein | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head | |
45 |
GAB3 | interactor | PH (PF00169, IPR001849, SM00233): PH domain | |
46 |
GPX1 | oncoprotein | GSHPx (PF00255, IPR000889): Glutathione peroxidase | |
47 |
GRAP2 | interactor | NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal SH2 (PF00017, IPR000980, SM00252): SH2 domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain | |
48 |
GRB10 | oncoprotein | BPS (PF08947, IPR015042): BPS (Between PH and SH2) PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH2 (PF00017, IPR000980, SM00252): SH2 domain Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos | |
49 |
GTF2F1 | interactor | TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) | |
50 |
HIPK2 | oncoprotein | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain | |
51 |
HNRNPM | interactor | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region | |
52 |
HSPE1 | interactor | Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit | |
53 |
HUWE1 | oncoprotein | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) | |
54 |
ILF3 | oncoprotein | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain | |
55 |
INPPL1 | oncoprotein | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SH2 (PF00017, IPR000980, SM00252): SH2 domain | |
56 |
JAK1 | oncoprotein | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain | |
57 |
JUN | oncoprotein | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor | |
58 |
LARS | interactor | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) | |
59 |
LRRC59 | interactor | Hid1 (PF12722): High-temperature-induced dauer-formation protein LRR_8 (PF13855, IPR001611): Leucine rich repeat DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366) | |
60 |
MAPT | interactor | Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat | |
61 |
MAVS | interactor | Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat CARD_2 (PF16739, IPR031964): Caspase recruitment domain | |
62 |
MBP | interactor | Myelin_MBP (PF01669, IPR000548): Myelin basic protein | |
63 |
MDM2 | oncoprotein | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) | |
64 |
MDM4 | oncoprotein | zf-FLZ (PF04570, IPR007650): zinc-finger of the FCS-type, C2-C2 SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) | |
65 |
MICAL1 | interactor | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DAO (PF01266, IPR006076): FAD dependent oxidoreductase FAD_binding_3 (PF01494, IPR002938): FAD binding domain LIM (PF00412, IPR001781, SM00132): LIM domain DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585) NAD_binding_7 (PF13241, IPR006367): Putative NAD(P)-binding | |
66 |
MSH5 | interactor | MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III | |
67 |
MTOR | oncoprotein | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat | |
68 |
MUC1 | oncoprotein | SEA (PF01390, IPR000082, SM00200): SEA domain Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator Collectrin (PF16959, IPR031588): Renal amino acid transporter | |
69 |
NAA25 | interactor | BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain NatB_MDM20 (PF09797, IPR019183): N-acetyltransferase B complex (NatB) non catalytic subunit ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation | |
70 |
NARS | interactor | tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain | |
71 |
NCK1 | oncoprotein | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain | |
72 |
NCOA3 | oncoprotein | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 | |
73 |
NEDD4 | suppressor | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) | |
74 |
NEDD4L | oncoprotein | WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) | |
75 |
NEDD9 | interactor | Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) SH3_9 (PF14604, IPR001452): Variant SH3 domain | |
76 |
PAG1 | interactor | PAG (PF15347, IPR032748): Phosphoprotein associated with glycosphingolipid-enriched | |
77 |
PAK2 | interactor | PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain Pkinase (PF00069, IPR000719): Protein kinase domain | |
78 |
PAK4 | interactor | PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain Pkinase (PF00069, IPR000719): Protein kinase domain | |
79 |
PARK2 | suppressor | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family | |
80 |
PARP1 | suppressor | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region | |
81 |
PCNA | oncoprotein | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain | |
82 |
PDE4D | oncoprotein | Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase | |
83 |
PFDN4 | interactor | Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit | |
84 |
PIK3R1 | oncoprotein | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain | |
85 |
PPM1B | interactor | PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain | |
86 |
PRDX1 | oncoprotein | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin | |
87 |
PRKDC | interactor | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase | |
88 |
PSMA4 | interactor | Proteasome (PF00227, IPR001353): Proteasome subunit U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature | |
89 |
PSMA7 | interactor | Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature | |
90 |
PSMD4 | interactor | UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain | |
91 |
PSTPIP1 | interactor | ABATE (PF07336, IPR010852): Putative stress-induced transcription regulator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain WXG100 (PF06013, IPR010310): Proteins of 100 residues with WXG Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 | |
92 |
RAD51 | interactor | Rad51 (PF08423, IPR013632): Rad51 HHH_5 (PF14520): Helix-hairpin-helix domain | |
93 |
RAD9A | oncoprotein | Rad9 (PF04139, IPR007268): Rad9 | |
94 |
RAPGEF1 | oncoprotein | RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif | |
95 |
RASA1 | oncoprotein | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain | |
96 |
REPS1 | interactor | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC) DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand | |
97 |
RFX1 | interactor | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region RFX1_trans_act (PF04589, IPR007668): RFX1 transcription activation region RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain | |
98 |
RPL37 | interactor | Ribosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e | |
99 |
RPLP1 | interactor | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein | |
100 |
RPS21 | interactor | Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e | |
101 |
RTFDC1 | interactor | Rtf2 (PF04641, IPR027799): Rtf2 RING-finger | |
102 |
SFN | suppressor | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein | |
103 |
SH3BP1 | interactor | BAR (PF03114, IPR004148, SM00721): BAR domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting | |
104 |
SH3KBP1 | interactor | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain | |
105 |
SHB | interactor | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein SH2 (PF00017, IPR000980, SM00252): SH2 domain Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region | |
106 |
SHD | interactor | SH2 (PF00017, IPR000980, SM00252): SH2 domain | |
107 |
SHE | interactor | SH2 (PF00017, IPR000980, SM00252): SH2 domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein | |
108 |
SLC9A2 | oncoprotein | Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin | |
109 |
SOCS1 | oncoprotein | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box | |
110 |
SOCS3 | suppressor | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box | |
111 |
SORBS1 | interactor | SH3_2 (PF07653, IPR011511): Variant SH3 domain Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain SCAB-ABD (PF16711, IPR032012): Actin-binding domain of plant-specific actin-binding protein | |
112 |
SORBS2 | oncoprotein | Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain | |
113 |
SPAG9 | interactor | DUF501 (PF04417, IPR007511): Protein of unknown function (DUF501) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IncA (PF04156, IPR007285): IncA protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449 JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II | |
114 |
SPRR2A | interactor | SPRR2 (PF14820, IPR029142): Small proline-rich 2 | |
115 |
SPTA1 | interactor | EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair | |
116 |
SPTAN1 | oncoprotein | EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Tetrabrachion (PF11401, IPR021535): Tetrabrachion EF-hand_7 (PF13499, IPR011992): EF-hand domain pair E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain | |
117 |
SRC | oncoprotein | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain | |
118 |
SRPK2 | oncoprotein | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) | |
119 |
ST5 | oncoprotein | dDENN (PF03455, IPR005112, SM00801): dDENN domain DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) uDENN (PF03456, IPR005113, SM00800): uDENN domain SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex | |
120 |
STK4 | oncoprotein | Pkinase (PF00069, IPR000719): Protein kinase domain Mst1_SARAH (PF11629, IPR024205): C terminal SARAH domain of Mst1 DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) | |
121 |
STON2 | interactor | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Stonin2_N (PF12016, IPR022699): Stonin 2 | |
122 |
SUB1 | interactor | Dehydrin (PF00257, IPR000167): Dehydrin PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4) | |
123 |
TERF1 | interactor | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain | |
124 |
TOPBP1 | interactor | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain | |
125 |
TUB | interactor | Tub (PF01167, IPR000007): Tub family Tub_N (PF16322, IPR005398): Tubby N-terminal | |
126 |
USP7 | oncoprotein | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal | |
127 |
VAV1 | oncoprotein | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain | |
128 |
WASF1 | interactor | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator WH2 (PF02205, IPR003124, SM00246): WH2 motif | |
129 |
WRNIP1 | interactor | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RuvB_N (PF05496, IPR008824): Holliday junction DNA helicase ruvB N-terminus Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) MgsA_C (PF12002, IPR021886): MgsA AAA+ ATPase C terminal AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain | |
130 |
XRCC6 | oncoprotein | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain | |
131 |
YAP1 | oncoprotein | Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181 | |
132 |
YTHDC1 | interactor | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family YTH (PF04146, IPR007275): YT521-B-like domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH | |
133 |
YWHAE | oncoprotein | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein | |
134 |
YWHAG | interactor | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein | |
135 |
YWHAH | interactor | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein | |
136 |
YWHAQ | interactor | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein | |
137 |
YWHAZ | interactor | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein | |
138 |
ZAP70 | interactor | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain | |
139 |
ZDHHC16 | interactor | DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049) NS3_envE (PF02723, IPR003873): Non-structural protein NS3/Small envelope protein E zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase | |