Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	85
The number (and %) of the onco-proteins	26 (30.59 %)
The number (and %) of the tumor suppressors	17 (20.00 %)
Total number of binary PPIs (saturation %)	808 (22.63 %)
The number (and %) of affected PPIs	84 (10.40 %)
The number of possible different fusions	23
PPI diameter	2
PPI radius	1
The average degree of PPI	18.212
Assortativity coefficient	-0.1878
The network average Clustering coefficient	0.572
The number (and %) of a zero Clustering coefficients	3 (3.53 %)
The number (and %) of a zero Betweenness Centrality	9 (10.59 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: SERBP1	All fusions : DL057459;
Proteins found in more fusions	APP (see 4 fusions); RPS24/RPS23 (see 1 fusions); SFPQ (see 6 fusions); U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); HUWE1 (see 2 fusions); CUL1 (see 3 fusions); PABPC1 (see 2 fusions); CUL3 (see 1 fusions); GRB2 (see 1 fusions); ATP5A1/HUWE1 (see 2 fusions); NF2 (see 1 fusions); KAT2B (see 1 fusions); PIAS1 (see 2 fusions); MCM2 (see 1 fusions); CSNK2A1 (see 1 fusions); CHD3 (see 1 fusions); ATP5A1 (see 1 fusions); TP53 (see 3 fusions); RPS19/RPS14 (see 1 fusions); TRIM29 (see 3 fusions);

List of the fusions

PPI for parental proteins: SERBP1

All fusions

: DL057459;

Proteins found in more fusions

APP (see 4 fusions); RPS24/RPS23 (see 1 fusions); SFPQ (see 6 fusions); U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); HUWE1 (see 2 fusions); CUL1 (see 3 fusions); PABPC1 (see 2 fusions); CUL3 (see 1 fusions); GRB2 (see 1 fusions); ATP5A1/HUWE1 (see 2 fusions); NF2 (see 1 fusions); KAT2B (see 1 fusions); PIAS1 (see 2 fusions); MCM2 (see 1 fusions); CSNK2A1 (see 1 fusions); CHD3 (see 1 fusions); ATP5A1 (see 1 fusions); TP53 (see 3 fusions); RPS19/RPS14 (see 1 fusions); TRIM29 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	DL057459	chimera	84	0.198	2705.050	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
2	AHSA1	interactor	16	0.667	8.048	Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
3	APP	protein found in more fusions	23	0.455	42.672	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4	ARRB2	interactor	15	0.543	10.911	Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
5	ATP5A1	protein found in more fusions	24	0.466	41.480	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
6	BASP1	suppressor	6	0.600	2.502	BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein)
7	CAND1	interactor	33	0.550	74.852	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
8	CD81	interactor	16	0.629	8.087	Tetraspannin (PF00335, IPR018499): Tetraspanin family
9	CHD3	oncoprotein	8	0.619	3.075	CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family
10	CSNK2A1	oncoprotein	20	0.386	47.645	Pkinase (PF00069, IPR000719): Protein kinase domain
11	CTNNB1	oncoprotein	14	0.451	15.196	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
12	CUL1	suppressor	33	0.502	78.520	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
13	CUL3	protein found in more fusions	40	0.429	152.167	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
14	DAXX	oncoprotein	6	0.600	1.651	Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
15	DYNC1H1	interactor	13	0.474	18.192	AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5
16	DYNC1I2	interactor	7	0.667	3.018	Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) Dynein_IC2 (PF11540, IPR025956): Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4329 (PF14220, IPR025479): Domain of unknown function (DUF4329)
17	DYNC1LI1	interactor	6	0.867	0.800	DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC)
18	DYNLT3	interactor	7	0.600	3.352	Tctex-1 (PF03645, IPR005334): Tctex-1 family
19	EIF2A	interactor	10	0.622	3.574	Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
20	ELAVL1	oncoprotein	24	0.304	94.956	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
21	ESR1	suppressor	28	0.453	75.268	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
22	FAU	interactor	20	0.647	14.269	Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30 ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
23	FBXO25	suppressor	8	0.679	2.546	Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
24	FBXW7	suppressor	4	1.000	0	Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like
25	FUS	suppressor	25	0.427	62.444	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
26	FXYD3	interactor	1	0	0	ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
27	FYTTD1	interactor	2	0	0	FYTT (PF07078, IPR009782): Forty-two-three protein
28	GARS	interactor	3	1.000	0	HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
29	GRB2	oncoprotein	15	0.549	14.143	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
30	HIST1H3E	interactor	10	0.756	1.629	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
31	HNRNPR	interactor	19	0.550	25.825	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
32	HNRNPU	interactor	43	0.413	212.586	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
33	HUWE1	oncoprotein	22	0.652	13.780	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
34	ISG15	suppressor	10	0.422	7.655	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
35	ITFG1	interactor	1	0	0	FG-GAP (PF01839, IPR013517): FG-GAP repeat K1 (PF02960, IPR004121): K1 glycoprotein VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
36	KAT2B	protein found in more fusions	7	0.533	2.953	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
37	MAP1LC3A	interactor	5	0.500	2.119	Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
38	MAP4	oncoprotein	8	0.464	4.584	SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
39	MCM2	oncoprotein	36	0.435	102.353	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
40	MDC1	suppressor	8	0.643	4.169	FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
41	NEDD8	interactor	15	0.582	14.543	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
42	NF2	suppressor	5	1.000	0	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
43	NPM1	suppressor	44	0.474	125.493	Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
44	NTRK1	oncoprotein	41	0.321	262.120	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
45	OTUB1	interactor	10	0.556	5.836	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
46	PA2G4	interactor	12	0.545	7.419	Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein
47	PABPC1	oncoprotein	28	0.450	67.422	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT
48	PAN2	interactor	22	0.606	28.967	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain
49	PARK2	suppressor	22	0.495	31.396	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
50	PIAS1	suppressor	6	0.800	0.917	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
51	PIAS3	oncoprotein	2	1.000	0	SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
52	PIAS4	interactor	7	0.571	5.682	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
53	PRMT8	interactor	5	0.667	0.393	PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
54	RPL10	suppressor	30	0.628	47.828	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
55	RPL37A	interactor	25	0.730	13.389	Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
56	RPL4	interactor	35	0.545	77.697	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
57	RPS10	interactor	32	0.587	58.435	S10_plectin (PF03501, IPR005326): Plectin/S10 domain
58	RPS14	protein found in more fusions	34	0.606	41.360	Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
59	RPS19	protein found in more fusions	35	0.551	65.603	Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
60	RPS20	interactor	31	0.587	49.719	Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
61	RPS23	protein found in more fusions	31	0.624	34.561	Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
62	RPS24	protein found in more fusions	30	0.664	31.169	Fascin (PF06268, IPR022768): Fascin domain Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
63	RPS25	interactor	34	0.602	49.150	Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
64	RPS26	interactor	25	0.667	28.407	Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
65	RPS29	interactor	19	0.784	14.306	Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e
66	RPS3	interactor	38	0.525	101.745	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
67	RPS6	interactor	36	0.544	85.325	Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
68	RPS6KB2	interactor	13	0.564	11.720	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
69	SFN	suppressor	20	0.596	16.340	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
70	SFPQ	oncoprotein	20	0.333	38.827	GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
71	SIRT7	interactor	24	0.457	47.823	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
72	TARDBP	interactor	29	0.574	37.497	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
73	TDG	interactor	3	1.000	0	Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
74	TDRD3	interactor	4	0.667	0.268	RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein TUDOR (PF00567, IPR002999, SM00333): Tudor domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain DUF3472 (PF11958, IPR021862): Domain of unknown function (DUF3472)
75	TERT	oncoprotein	4	0.833	0.500	RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
76	TOPORS	suppressor	3	0.667	0.222	Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
77	TP53	suppressor	36	0.331	227.564	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
78	TRIM29	protein found in more fusions	7	0.600	2.358	MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
79	TSR1	interactor	20	0.837	4.185	AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein
80	U2AF2	protein found in more fusions	21	0.595	16.476	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
81	UBA2	interactor	3	0.667	0.182	ThiF (PF00899, IPR000594): ThiF family UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
82	UPF2	interactor	7	0.667	0.801	DDHD (PF02862, IPR004177, SM01127): DDHD domain DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) MIF4G (PF02854, IPR003890, SM00543): MIF4G domain Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
83	VAV2	oncoprotein	4	1.000	0	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein
84	VIM	suppressor	21	0.242	71.461	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
85	WDR5	interactor	9	0.528	4.825	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat

B a c k t o T o p ⇑

List of missing interactors

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	PCAP	oncoprotein	NA
2	SERBP1	parental protein	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal

B a c k t o T o p ⇑

Fusion ID: Protein names:	DL057459
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List of the fusions

List of active interactors

List of missing interactors