1 |
DL057459 | chimera | 84 | 0.198 | 2705.050 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
2 |
AHSA1 | interactor | 16 | 0.667 | 8.048 | Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein |
3 |
APP | protein found in more fusions | 23 | 0.455 | 42.672 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
4 |
ARRB2 | interactor | 15 | 0.543 | 10.911 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
5 |
ATP5A1 | protein found in more fusions | 24 | 0.466 | 41.480 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain |
6 |
BASP1 | suppressor | 6 | 0.600 | 2.502 | BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein) |
7 |
CAND1 | interactor | 33 | 0.550 | 74.852 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
8 |
CD81 | interactor | 16 | 0.629 | 8.087 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
9 |
CHD3 | oncoprotein | 8 | 0.619 | 3.075 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family |
10 |
CSNK2A1 | oncoprotein | 20 | 0.386 | 47.645 | Pkinase (PF00069, IPR000719): Protein kinase domain |
11 |
CTNNB1 | oncoprotein | 14 | 0.451 | 15.196 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
12 |
CUL1 | suppressor | 33 | 0.502 | 78.520 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
13 |
CUL3 | protein found in more fusions | 40 | 0.429 | 152.167 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
14 |
DAXX | oncoprotein | 6 | 0.600 | 1.651 | Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) |
15 |
DYNC1H1 | interactor | 13 | 0.474 | 18.192 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
16 |
DYNC1I2 | interactor | 7 | 0.667 | 3.018 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) Dynein_IC2 (PF11540, IPR025956): Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4329 (PF14220, IPR025479): Domain of unknown function (DUF4329) |
17 |
DYNC1LI1 | interactor | 6 | 0.867 | 0.800 | DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC) |
18 |
DYNLT3 | interactor | 7 | 0.600 | 3.352 | Tctex-1 (PF03645, IPR005334): Tctex-1 family |
19 |
EIF2A | interactor | 10 | 0.622 | 3.574 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A |
20 |
ELAVL1 | oncoprotein | 24 | 0.304 | 94.956 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
21 |
ESR1 | suppressor | 28 | 0.453 | 75.268 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
22 |
FAU | interactor | 20 | 0.647 | 14.269 | Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30 ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
23 |
FBXO25 | suppressor | 8 | 0.679 | 2.546 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A |
24 |
FBXW7 | suppressor | 4 | 1.000 | 0 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
25 |
FUS | suppressor | 25 | 0.427 | 62.444 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
26 |
FXYD3 | interactor | 1 | 0 | 0 | ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family |
27 |
FYTTD1 | interactor | 2 | 0 | 0 | FYTT (PF07078, IPR009782): Forty-two-three protein |
28 |
GARS | interactor | 3 | 1.000 | 0 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
29 |
GRB2 | oncoprotein | 15 | 0.549 | 14.143 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
30 |
HIST1H3E | interactor | 10 | 0.756 | 1.629 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
31 |
HNRNPR | interactor | 19 | 0.550 | 25.825 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
32 |
HNRNPU | interactor | 43 | 0.413 | 212.586 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
33 |
HUWE1 | oncoprotein | 22 | 0.652 | 13.780 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
34 |
ISG15 | suppressor | 10 | 0.422 | 7.655 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
35 |
ITFG1 | interactor | 1 | 0 | 0 | FG-GAP (PF01839, IPR013517): FG-GAP repeat K1 (PF02960, IPR004121): K1 glycoprotein VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella |
36 |
KAT2B | protein found in more fusions | 7 | 0.533 | 2.953 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
37 |
MAP1LC3A | interactor | 5 | 0.500 | 2.119 | Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like |
38 |
MAP4 | oncoprotein | 8 | 0.464 | 4.584 | SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275) |
39 |
MCM2 | oncoprotein | 36 | 0.435 | 102.353 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
40 |
MDC1 | suppressor | 8 | 0.643 | 4.169 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
41 |
NEDD8 | interactor | 15 | 0.582 | 14.543 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
42 |
NF2 | suppressor | 5 | 1.000 | 0 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
43 |
NPM1 | suppressor | 44 | 0.474 | 125.493 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
44 |
NTRK1 | oncoprotein | 41 | 0.321 | 262.120 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
45 |
OTUB1 | interactor | 10 | 0.556 | 5.836 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
46 |
PA2G4 | interactor | 12 | 0.545 | 7.419 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein |
47 |
PABPC1 | oncoprotein | 28 | 0.450 | 67.422 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
48 |
PAN2 | interactor | 22 | 0.606 | 28.967 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
49 |
PARK2 | suppressor | 22 | 0.495 | 31.396 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
50 |
PIAS1 | suppressor | 6 | 0.800 | 0.917 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544 |
51 |
PIAS3 | oncoprotein | 2 | 1.000 | 0 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
52 |
PIAS4 | interactor | 7 | 0.571 | 5.682 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
53 |
PRMT8 | interactor | 5 | 0.667 | 0.393 | PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) |
54 |
RPL10 | suppressor | 30 | 0.628 | 47.828 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
55 |
RPL37A | interactor | 25 | 0.730 | 13.389 | Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family |
56 |
RPL4 | interactor | 35 | 0.545 | 77.697 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
57 |
RPS10 | interactor | 32 | 0.587 | 58.435 | S10_plectin (PF03501, IPR005326): Plectin/S10 domain |
58 |
RPS14 | protein found in more fusions | 34 | 0.606 | 41.360 | Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11 |
59 |
RPS19 | protein found in more fusions | 35 | 0.551 | 65.603 | Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e |
60 |
RPS20 | interactor | 31 | 0.587 | 49.719 | Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e |
61 |
RPS23 | protein found in more fusions | 31 | 0.624 | 34.561 | Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23 |
62 |
RPS24 | protein found in more fusions | 30 | 0.664 | 31.169 | Fascin (PF06268, IPR022768): Fascin domain Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
63 |
RPS25 | interactor | 34 | 0.602 | 49.150 | Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein |
64 |
RPS26 | interactor | 25 | 0.667 | 28.407 | Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e |
65 |
RPS29 | interactor | 19 | 0.784 | 14.306 | Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e |
66 |
RPS3 | interactor | 38 | 0.525 | 101.745 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
67 |
RPS6 | interactor | 36 | 0.544 | 85.325 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
68 |
RPS6KB2 | interactor | 13 | 0.564 | 11.720 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
69 |
SFN | suppressor | 20 | 0.596 | 16.340 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
70 |
SFPQ | oncoprotein | 20 | 0.333 | 38.827 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
71 |
SIRT7 | interactor | 24 | 0.457 | 47.823 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
72 |
TARDBP | interactor | 29 | 0.574 | 37.497 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
73 |
TDG | interactor | 3 | 1.000 | 0 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily |
74 |
TDRD3 | interactor | 4 | 0.667 | 0.268 | RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein TUDOR (PF00567, IPR002999, SM00333): Tudor domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain DUF3472 (PF11958, IPR021862): Domain of unknown function (DUF3472) |
75 |
TERT | oncoprotein | 4 | 0.833 | 0.500 | RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain |
76 |
TOPORS | suppressor | 3 | 0.667 | 0.222 | Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
77 |
TP53 | suppressor | 36 | 0.331 | 227.564 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
78 |
TRIM29 | protein found in more fusions | 7 | 0.600 | 2.358 | MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger |
79 |
TSR1 | interactor | 20 | 0.837 | 4.185 | AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein |
80 |
U2AF2 | protein found in more fusions | 21 | 0.595 | 16.476 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
81 |
UBA2 | interactor | 3 | 0.667 | 0.182 | ThiF (PF00899, IPR000594): ThiF family UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus |
82 |
UPF2 | interactor | 7 | 0.667 | 0.801 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) MIF4G (PF02854, IPR003890, SM00543): MIF4G domain Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain |
83 |
VAV2 | oncoprotein | 4 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein |
84 |
VIM | suppressor | 21 | 0.242 | 71.461 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
85 |
WDR5 | interactor | 9 | 0.528 | 4.825 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |