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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: DB371979 is the fusion of parental proteins S100A6, PRPF8 (from a repository: Wed Dec 7 16:44:27 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)172
The number (and %) of the onco-proteins49 (28.49 %)
The number (and %) of the tumor suppressors21 (12.21 %)
Total number of binary PPIs (saturation %)2451 (16.67 %)
The number (and %) of affected PPIs171 (6.98 %)
The number of possible different fusions31
PPI diameter2
PPI radius1
The average degree of PPI27.791
Assortativity coefficient-0.1691
The network average Clustering coefficient0.498
The number (and %) of a zero Clustering coefficients2 (1.16 %)
The number (and %) of a zero Betweenness Centrality12 (6.98 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: S100A6,PRPF8 All fusions
: DB371979;
Proteins found in more fusions PRPF19 (see 2 fusions); U2AF2 (see 2 fusions); RANGAP1 (see 2 fusions); SART3 (see 2 fusions); PRKDC (see 3 fusions); PIP4K2B (see 3 fusions); HDAC5 (see 1 fusions); RPA1 (see 1 fusions); NEDD4 (see 1 fusions); PRPF3 (see 1 fusions); SUZ12 (see 2 fusions); SNW1 (see 1 fusions); ZMYND11 (see 1 fusions); HSP90AA1 (see 2 fusions); HUWE1 (see 2 fusions); SRPK2 (see 1 fusions); SNRNP200 (see 3 fusions); TCF3 (see 4 fusions); STUB1 (see 1 fusions); PRPF6 (see 1 fusions); STAU1 (see 2 fusions); NUP214 (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); UBC (see 1 fusions); TP53 (see 3 fusions); LUC7L2 (see 2 fusions); PABPC1 (see 2 fusions); FN1/RPL6 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DB371979chimera1710.15310656.897PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
CR6_interact (PF10147, IPR018472): Growth arrest and DNA-damage-inducible proteins-interacting protein 1
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
2 AAR2interactor80.5714.452AAR2 (PF05282, IPR007946): AAR2 protein
3 ABATinteractor21.0000Aminotran_3 (PF00202, IPR005814): Aminotransferase class-III
4 ABCA1oncoprotein100ABC_tran (PF00005, IPR003439): ABC transporter
ABC2_membrane_3 (PF12698): ABC-2 family transporter protein
AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
DUF4162 (PF13732, IPR025302): Domain of unknown function (DUF4162)
5 ANXA11interactor60.5330.808Annexin (PF00191, IPR018502, SM00335): Annexin
6 ARoncoprotein160.37125.836Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
7 ASB15interactor21.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
8 BCAS2interactor310.53132.328BCAS2 (PF05700, IPR008409): Breast carcinoma amplified sequence 2 (BCAS2)
ZapB (PF06005, IPR009252): Cell division protein ZapB
9 BSGinteractor80.5364.315Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
10 CACYBPinteractor100.5286.057CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
Siah-Interact_N (PF09032, IPR015120): Siah interacting protein, N terminal
11 CCDC8interactor360.398100.254Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
12 CD2BP2interactor180.55616.835GYF (PF02213, IPR003169, SM00444): GYF domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
13 CDC40interactor160.60811.589AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
14 CDC5Linteractor770.350532.458OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
15 CDK2suppressor390.323142.503Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
16 CDKN1Asuppressor110.6004.052CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
17 CLNS1Ainteractor120.5919.673Voldacs (PF03517): Regulator of volume decrease after cellular swelling
18 CRNKL1interactor220.54123.177NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
HAT (PF02184, IPR003107, SM00386): HAT (Half-A-TPR) repeat
Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
U3_assoc_6 (PF08640, IPR013949): U3 small nucleolar RNA-associated protein 6
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
19 CUL3protein found in more fusions800.284716.482Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
20 CUL7protein found in more fusions670.337316.015ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
21 DDX23interactor390.363218.986DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3698 (PF12479, IPR022167): Protein of unknown function (DUF3698)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
22 DDX3Xsuppressor350.31977.269DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
23 DHX15interactor520.404153.113DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
24 DHX36interactor110.40013.189DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
25 DHX9oncoprotein520.394149.246DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
26 ECDinteractor70.3816.433Bradykinin (PF06753, IPR009608): Bradykinin
SGT1 (PF07093, IPR010770): SGT1 protein
27 EEDsuppressor460.438101.706WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
28 EFTUD2interactor710.353446.340EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
29 EIF4A3interactor600.441183.431DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
30 ERGoncoprotein190.40422.877Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
31 ESR1suppressor510.310264.094Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
32 FBXO6interactor250.37742.567FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
33 FKBP4interactor110.4369.756FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
34 FN1oncoprotein460.321179.022fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
35 FOXM1oncoprotein60.7330.552EspF (PF04806, IPR006891): EspF protein repeat
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
36 FOXQ1interactor100.4224.764Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
37 G3BP2interactor150.5249.699NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
38 GCFC2interactor70.6194.130DUF1676 (PF07898, IPR012464): Protein of unknown function (DUF1676)
GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein
39 GIGYF2interactor150.42923.041DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
GYF (PF02213, IPR003169, SM00444): GYF domain
Macoilin (PF09726, IPR019130): Transmembrane protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
AAA_23 (PF13476): AAA domain
ARGLU (PF15346): Arginine and glutamate-rich 1
PRTase_3 (PF15610, IPR028944): PRTase ComF-like
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
40 GPKOWinteractor40.6671.000KOW (PF00467, IPR005824, SM00739): KOW motif
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
41 HDAC5protein found in more fusions320.41361.118Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
42 HEBP1interactor30.6670.667SOUL (PF04832, IPR006917): SOUL heme-binding protein
43 HNRNPA1interactor590.405189.545RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
44 HNRNPH2interactor190.43119.535RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
45 HNRNPMinteractor590.383209.214RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
46 HNRNPRinteractor500.493119.182RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
47 HNRNPUinteractor690.332394.448CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
48 HSP90AA1oncoprotein390.344159.031HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
49 HUWE1oncoprotein380.375110.585BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
50 ICAM1oncoprotein160.37513.052Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
51 IGSF8oncoprotein210.38122.907V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
52 ISY1interactor190.49021.296Isy1 (PF06246, IPR009360): Isy1-like splicing family
53 ISY1-RAB43interactor100.7781.678Isy1 (PF06246, IPR009360): Isy1-like splicing family
54 ITGA4interactor340.41566.187FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
55 KPNA4interactor40.6670.192Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
56 LGR4interactor150.29719.9117tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
57 LUC7L2protein found in more fusions300.48848.716LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
58 MAGOHinteractor380.46473.210Mago_nashi (PF02792, IPR004023): Mago nashi protein
59 MCM5oncoprotein320.47848.574MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
60 MDM2oncoprotein320.344125.115Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
61 MED12oncoprotein90.4728.963Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877)
Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain
Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
62 MED13oncoprotein50.8000.543Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal
Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal
63 MEPCEinteractor290.49035.014Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3)
Methyltransf_23 (PF13489): Methyltransferase domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
64 MEX3Cinteractor60.4671.480KH_1 (PF00013, IPR004088, SM00322): KH domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
65 MYBBP1Asuppressor270.42556.703DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
66 MYConcoprotein280.39671.019HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
67 NACAoncoprotein80.6071.162NAC (PF01849, IPR002715): NAC domain
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
CitT (PF12431, IPR028141): Transcriptional regulator
68 NEDD4suppressor100.5007.335Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
69 NOP2interactor230.45520.575BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
70 NOTCH1suppressor110.5332.757Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
71 NTRK1oncoprotein860.2261147.392I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
72 NUP214oncoprotein140.3598.119dCache_2 (PF08269, IPR004010, SM01049): Cache domain
HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1
NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159
73 NXF1interactor390.299203.774NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
74 OBSL1interactor660.347275.003BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
75 PABPC1oncoprotein480.367171.648RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
76 PCBP1oncoprotein290.305101.882Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
77 PEX5interactor40.6670.686TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
SHNi-TPR (PF10516, IPR019544): SHNi-TPR
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_15 (PF13429): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
78 PHF6suppressor100.6442.810zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
YqfQ (PF14181, IPR025571): YqfQ-like protein
79 PIN1suppressor180.52319.566Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
80 PIP4K2Ainteractor21.0000PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
81 PIP4K2Bprotein found in more fusions31.0000PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
82 PIP4K2Cinteractor31.0000PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
83 PLRG1interactor240.68812.908WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
84 PPIDinteractor60.6001.184Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
85 PRKDCprotein found in more fusions380.341106.522FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
86 PRPF19protein found in more fusions580.445197.213Prp19 (PF08606, IPR013915): Prp19/Pso4-like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
87 PRPF3protein found in more fusions400.47688.287DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115)
PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3)
PWI (PF01480, IPR002483, SM00311): PWI domain
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
88 PRPF31interactor290.63521.675Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
Cytokin_check_N (PF10407, IPR018844): Cdc14 phosphatase binding protein N-terminus
Prp31_C (PF09785, IPR019175): Prp31 C terminal domain
89 PRPF4interactor320.59141.741PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
90 PRPF4Boncoprotein240.56217.435Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
Ureide_permease (PF07168, IPR009834): Ureide permease
Pkinase (PF00069, IPR000719): Protein kinase domain
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
91 PRPF6protein found in more fusions500.419196.452PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
92 PSMD14interactor50.8000.536JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
93 RALYinteractor300.51340.185RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
94 RANBP2oncoprotein320.40082.796Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693)
IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain
Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
95 RANGAP1protein found in more fusions180.52911.144RanGAP1_C (PF07834, IPR009109): RanGAP1 C-terminal domain
SDA1 (PF05285, IPR007949): SDA1
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
96 RBM5suppressor90.7780.800DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
97 RNF2interactor520.377199.362zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
98 RNPS1interactor370.47465.637RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
Macoilin (PF09726, IPR019130): Transmembrane protein
99 RPA1suppressor410.50458.151Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
100 RPA2oncoprotein370.46252.006RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
101 RPA3interactor330.48234.750Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
102 RPL37Ainteractor140.6593.897Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
103 RPL6protein found in more fusions380.44067.422Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
104 RPLP0interactor350.39267.009Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
105 RPS14interactor280.46335.643Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
106 RPS25interactor210.49024.114Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
107 S100A4interactor90.36113.450S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
108 S100A9oncoprotein180.44120.530S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
109 S100Boncoprotein51.0000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
110 SART1interactor520.474144.333SART-1 (PF03343, IPR005011): SART-1 family
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
111 SART3protein found in more fusions220.33345.073CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866)
DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993)
Lsm_interact (PF05391, IPR008669): Lsm interaction motif
Phage_GPD (PF05954): Phage late control gene D protein (GPD)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_14 (PF13428): Tetratricopeptide repeat
MRI (PF15325, IPR028278): Modulator of retrovirus infection
LSM_int_assoc (PF16605): LSM-interacting associated unstructured
112 SCARB2interactor21.0000CD36 (PF01130, IPR002159): CD36 family
113 SEC23Ainteractor120.40912.980Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
114 SEC24Ainteractor60.6672.389Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
115 SEPT2oncoprotein140.6375.265FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Septin (PF00735, IPR000038): Septin
116 SEPT7interactor150.52414.593Fez1 (PF06818): Fez1
Septin (PF00735, IPR000038): Septin
117 SERPINB2interactor100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
118 SF3A1interactor530.454157.088TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
119 SF3A2interactor460.493114.010Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
120 SF3B1oncoprotein590.434174.843Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
121 SF3B2interactor400.423109.977DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382)
PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region
PSP (PF04046, IPR006568, SM00581): PSP
SAP (PF02037, IPR003034, SM00513): SAP domain
Usp (PF00582, IPR006016): Universal stress protein family
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
122 SF3B3interactor630.411247.746CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
123 SF3B4interactor210.63314.995RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
124 SF3B6interactor320.55037.693RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
125 SHMT2interactor130.4875.970SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
126 SIRT6suppressor100.31116.321SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
127 SIRT7interactor450.253208.428DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
128 SLU7interactor50.7000.467Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Slu7 (PF11708, IPR021715): Pre-mRNA splicing Prp18-interacting factor
zf-CCHC_4 (PF14392, IPR025836): Zinc knuckle
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
129 SMU1interactor110.5454.264LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
130 SND1interactor230.51814.655TUDOR (PF00567, IPR002999, SM00333): Tudor domain
SNase (PF00565, IPR016071, SM00318): Staphylococcal nuclease homologue
131 SNRNP200protein found in more fusions830.320704.051DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
132 SNRNP40interactor330.48966.786WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
133 SNRNP70interactor340.53335.584RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
134 SNRPA1interactor490.469152.969LRR_9 (PF14580): Leucine-rich repeat
135 SNRPBinteractor290.42153.909LSM (PF01423, IPR001163): LSM domain
136 SNRPD1interactor500.494108.700API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
LSM (PF01423, IPR001163): LSM domain
137 SNRPD2interactor470.48599.959LSM (PF01423, IPR001163): LSM domain
138 SNRPD3interactor420.52665.822LSM (PF01423, IPR001163): LSM domain
139 SNRPEinteractor190.62011.143LSM (PF01423, IPR001163): LSM domain
140 SNW1protein found in more fusions670.385347.748SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
141 SRPK1interactor260.48628.019FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
142 SRPK2oncoprotein350.41782.179DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
143 SRRM1interactor360.52456.904DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen
MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
PWI (PF01480, IPR002483, SM00311): PWI domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
144 SRRM2interactor500.496133.567cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
145 STAU1protein found in more fusions330.47440.124dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
146 STUB1suppressor140.37224.744U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
147 SUGT1interactor80.6435.333CheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
148 SUPT16Hinteractor280.44231.599Nop14 (PF04147, IPR007276): Nop14-like family
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
FACT-Spt16_Nlob (PF14826, IPR029148): FACT complex subunit SPT16 N-terminal lobe domain
149 SUZ12suppressor450.424121.517DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
150 TCF3suppressor50.5000.671CDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
151 TM9SF4interactor21.0000EMP70 (PF02990, IPR004240): Endomembrane protein 70
DUF4229 (PF14012, IPR025323): Protein of unknown function (DUF4229)
152 TOM1L2suppressor40.6671.067GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
153 TOP1oncoprotein400.48263.783DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region
154 TP53suppressor540.282377.885DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
155 TRIM55interactor150.4849.480Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
NABP (PF07990, IPR012940): Nucleic acid binding protein NABP
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
156 TSSC4suppressor160.53321.756TSSC4 (PF15264, IPR029338): Tumour suppressing sub-chromosomal transferable candidate 4
157 TUBA4Ainteractor160.42510.794Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
158 U2AF1oncoprotein420.49976.510DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
159 U2AF2protein found in more fusions640.424237.589RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
160 UBCprotein found in more fusions380.338166.860ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
161 UBE2Iinteractor330.292139.375UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
162 USP39oncoprotein330.48954.299UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
163 USP9Xinteractor150.42929.366DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722)
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
164 VCAM1interactor310.39651.759C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
165 VTNinteractor190.61412.332Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain
166 WDR83interactor110.43617.904WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
167 WWOXsuppressor280.47138.206adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
168 YEATS4interactor21.0000YEATS (PF03366, IPR005033): YEATS family
SOGA (PF11365, IPR027881): Protein SOGA
169 ZBTB46interactor21.0000ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
C1_2 (PF03107, IPR004146): C1 domain
Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
DUF4428 (PF14471, IPR027872): Domain of unknown function (DUF4428)
170 ZBTB7Binteractor60.5001.008BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GAGA (PF09237, IPR015318): GAGA factor
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
171 ZMYND11suppressor110.5562.799DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002)
DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353)
PWWP (PF00855, IPR000313, SM00293): PWWP domain
zf-MYND (PF01753, IPR002893): MYND finger
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
172 ZNF830interactor60.7330.421Sec34 (PF04136, IPR007265): Sec34-like family
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 PRPF8parental proteinPRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
2 RNU11interactorNA
3 RNU12interactorNA
4 S100A6parental proteinS_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair

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