Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: DB135958 is the fusion of parental proteins NAMPT, CD69 (from a repository: Wed Mar 29 00:34:36 2017)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)2
The number (and %) of the onco-proteins1 (50.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)1 (100.00 %)
The number (and %) of affected PPIs1 (100.00 %)
The number of possible different fusions1
PPI diameter1
PPI radius1
The average degree of PPI1.000
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients2 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (100.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: CD69,NAMPT All fusions
: DB135958;
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DB135958chimera100Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
2 TMEM190interactor100TMEM190 (PF15431, IPR028248): Transmembrane protein 190

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ADORA2Aoncoprotein7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
2 AKT2oncoproteinPH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
3 ANXA6interactorAnnexin (PF00191, IPR018502, SM00335): Annexin
4 ASS1suppressorArginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase
5 CD69parental proteinLectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
6 CD81interactorTetraspannin (PF00335, IPR018499): Tetraspanin family
7 CTSAinteractorPeptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
8 CUL5suppressorCullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
9 DDA1interactorDDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
10 FANCAoncoproteinFanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
11 FBXW11interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
12 FTLinteractorFerritin (PF00210, IPR008331): Ferritin-like domain
13 GBASinteractorNIPSNAP (PF07978, IPR012577): NIPSNAP
14 GGT1interactorG_glu_transpept (PF01019, IPR000101): Gamma-glutamyltranspeptidase
DUF4148 (PF13663, IPR025421): Domain of unknown function (DUF4148)
15 GSRinteractorPyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
16 HNRNPA1interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
17 HNRNPH1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
18 HSPB1oncoproteinHSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
19 IFITM3interactorCD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
20 MVDinteractorGHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
21 NAMPTparental proteinNAPRTase (PF04095, IPR007229): Nicotinate phosphoribosyltransferase (NAPRTase) family
22 NAPRTinteractorNAPRTase (PF04095, IPR007229): Nicotinate phosphoribosyltransferase (NAPRTase) family
23 ND1interactorNA
24 NDRG1suppressorNdr (PF03096, IPR004142): Ndr family
25 NTRK1oncoproteinI-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
26 NXF1interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
27 PEPDinteractorAMP_N (PF05195, IPR007865, SM01011): Aminopeptidase P, N-terminal domain
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
DUF3793 (PF12672, IPR024523): Protein of unknown function (DUF3793)
28 TMEM25interactorC2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
DUF4674 (PF15719, IPR029779): Domain of unknown function (DUF4674)
29 U2AF2interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein

B a c k    t o    T o p ⇑