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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: DB135958 is the fusion of parental proteins NAMPT, CD69 (from a repository: Wed Mar 29 00:34:36 2017)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)2
The number (and %) of the onco-proteins1 (50.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)1 (100.00 %)
The number (and %) of affected PPIs1 (100.00 %)
The number of possible different fusions1
PPI diameter1
PPI radius1
The average degree of PPI1.000
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients2 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (100.00 %)


List of the fusions

PPI for parental proteins: CD69,NAMPT All fusions
: DB135958;
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 DB135958chimera100Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
2 TMEM190interactor100TMEM190 (PF15431, IPR028248): Transmembrane protein 190

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ADORA2Aoncoprotein7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
2 AKT2oncoproteinPH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
3 ANXA6interactorAnnexin (PF00191, IPR018502, SM00335): Annexin
4 ASS1suppressorArginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase
5 CD69parental proteinLectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
6 CD81interactorTetraspannin (PF00335, IPR018499): Tetraspanin family
7 CTSAinteractorPeptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
8 CUL5suppressorCullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
9 DDA1interactorDDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
10 FANCAoncoproteinFanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
11 FBXW11interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
12 FTLinteractorFerritin (PF00210, IPR008331): Ferritin-like domain
13 GBASinteractorNIPSNAP (PF07978, IPR012577): NIPSNAP
14 GGT1interactorG_glu_transpept (PF01019, IPR000101): Gamma-glutamyltranspeptidase
DUF4148 (PF13663, IPR025421): Domain of unknown function (DUF4148)
15 GSRinteractorPyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
16 HNRNPA1interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
17 HNRNPH1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
18 HSPB1oncoproteinHSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
19 IFITM3interactorCD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
20 MVDinteractorGHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
21 NAMPTparental proteinNAPRTase (PF04095, IPR007229): Nicotinate phosphoribosyltransferase (NAPRTase) family
22 NAPRTinteractorNAPRTase (PF04095, IPR007229): Nicotinate phosphoribosyltransferase (NAPRTase) family
23 ND1interactorNA
24 NDRG1suppressorNdr (PF03096, IPR004142): Ndr family
25 NTRK1oncoproteinI-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
26 NXF1interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
27 PEPDinteractorAMP_N (PF05195, IPR007865, SM01011): Aminopeptidase P, N-terminal domain
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
DUF3793 (PF12672, IPR024523): Protein of unknown function (DUF3793)
28 TMEM25interactorC2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
DUF4674 (PF15719, IPR029779): Domain of unknown function (DUF4674)
29 U2AF2interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein

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