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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: DA833622 is the fusion of parental proteins CYP19A1, MYO1C (from a repository: Sat May 13 08:45:10 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)156
The number (and %) of the onco-proteins34 (21.79 %)
The number (and %) of the tumor suppressors20 (12.82 %)
Total number of binary PPIs (saturation %)1252 (10.36 %)
The number (and %) of affected PPIs155 (12.38 %)
The number of possible different fusions17
PPI diameter2
PPI radius1
The average degree of PPI15.641
Assortativity coefficient-0.3078
The network average Clustering coefficient0.572
The number (and %) of a zero Clustering coefficients10 (6.41 %)
The number (and %) of a zero Betweenness Centrality28 (17.95 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: MYO1C,CYP19A1 All fusions
: DA833622;
Proteins found in more fusions GRK5 (see 4 fusions); CBL (see 1 fusions); KIF11 (see 1 fusions); KAT2B (see 1 fusions); SORBS2 (see 4 fusions); LRRK2 (see 1 fusions); RPA1 (see 1 fusions); TP53 (see 3 fusions); SUZ12 (see 2 fusions); SRSF2 (see 1 fusions); SP1 (see 1 fusions); IMPDH2 (see 2 fusions); KHDRBS1 (see 1 fusions); USP20 (see 1 fusions); EGFR (see 2 fusions); SHC1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DA833622chimera1550.08913609.503Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
p450 (PF00067, IPR001128): Cytochrome P450
2 ABLIM1interactor150.7905.610LIM (PF00412, IPR001781, SM00132): LIM domain
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
3 ACTN4interactor210.57623.394CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
4 ADD1interactor110.6913.126Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
5 AFAP1interactor150.8572.517PH (PF00169, IPR001849, SM00233): PH domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Enkurin (PF13864, IPR027012): Calmodulin-binding
6 AGGF1interactor31.0000DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
FHA (PF00498, IPR000253, SM00240): FHA domain
G-patch (PF01585, IPR000467, SM00443): G-patch domain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
WW (PF00397, IPR001202, SM00456): WW domain
YL1_C (PF08265, IPR013272, SM00993): YL1 nuclear protein C-terminal domain
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
7 ANLNoncoprotein440.385124.617Anillin (PF08174, IPR012966): Cell division protein anillin
PH (PF00169, IPR001849, SM00233): PH domain
Anillin_N (PF16018, IPR031970): Anillin N-terminus
8 AP3M1interactor50.6002.533Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
9 ARHGAP11Ainteractor110.9820.048RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
10 ARHGAP21interactor140.8134.092PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
MAJIN (PF15077, IPR027816): Membrane-anchored junction protein
PH_9 (PF15410): Pleckstrin homology domain
11 ARPC1Binteractor140.7143.495WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
12 ARRB1interactor150.40032.540Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
13 ARRB2interactor230.38360.577Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
14 BASP1suppressor120.9240.355BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein)
15 BAZ1Binteractor40.6670.750D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
DDT (PF02791, IPR004022, SM00571): DDT domain
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PHD (PF00628, IPR019787, SM00249): PHD-finger
YL1 (PF05764, IPR008895): YL1 nuclear protein
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635)
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
FAM176 (PF14851): FAM176 family
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
16 C17orf49interactor21.0000Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
17 CAPZA2interactor610.287436.506F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
18 CARD10interactor51.0000CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
19 CBLsuppressor160.49520.431Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
20 CCAR1suppressor80.39310.844Cucumo_2B (PF03263, IPR004946): Cucumovirus protein 2B
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
IncA (PF04156, IPR007285): IncA protein
Presenilin (PF01080, IPR001108): Presenilin
SAP (PF02037, IPR003034, SM00513): SAP domain
FimP (PF09766, IPR019163): Fms-interacting protein
DBC1 (PF14443, IPR025954, SM01122): DBC1
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
S1-like (PF14444, IPR025223): S1-like
DUF4481 (PF14800, IPR028054): Domain of unknown function (DUF4481)
FAM176 (PF14851): FAM176 family
21 CCDC127interactor100Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
Metal_resist (PF13801, IPR025961): Heavy-metal resistance
22 CDK2suppressor460.300344.458Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
23 CDKN2Asuppressor70.5242.668Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
24 CEP162interactor170.38244.629DivIC (PF04977, IPR007060): Septum formation initiator
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Methyltransf_14 (PF08484, IPR013691): C-methyltransferase C-terminal domain
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
DUF2553 (PF10830, IPR020140): Protein of unknown function (DUF2553)
DUF3073 (PF11273, IPR021426): Protein of unknown function (DUF3073)
PIP49_N (PF14875, IPR029244): N-term cysteine-rich ER, FAM69
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
FAM76 (PF16046, IPR032017): FAM76 protein
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
25 CFL1interactor250.51047.272Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
26 CFL2interactor170.8085.999Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
27 CHCHD3interactor60.4002.015DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737)
eIF3g (PF12353, IPR024675): Eukaryotic translation initiation factor 3 subunit G
28 CHERPinteractor90.5289.637CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
G-patch (PF01585, IPR000467, SM00443): G-patch domain
HpaP (PF09483, IPR013390): Type III secretion protein (HpaP)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
Surp (PF01805, IPR000061, SM00648): Surp module
29 CIAO1interactor30.6671.000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
30 CLASP1interactor21.0000HEAT (PF02985, IPR000357): HEAT repeat
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
31 COBLinteractor160.7424.115CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Cobl (PF09469, IPR019025): Cordon-bleu ubiquitin-like domain
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
PRIMA1 (PF16101): Proline-rich membrane anchor 1
32 CORO1Concoprotein190.65510.835DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
33 CORO2Aoncoprotein110.9820.048Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
34 CRIP2oncoprotein100LIM (PF00412, IPR001781, SM00132): LIM domain
35 CSTF2Tinteractor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
36 DBN1oncoprotein610.317424.763Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
37 DDX21interactor90.4174.652CRT10 (PF08728, IPR014839): CRT10
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
GUCT (PF08152, IPR012562): GUCT (NUC152) domain
Sulfatase (PF00884, IPR000917): Sulfatase
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
38 DDX39Binteractor60.6003.432DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
39 DIXDC1interactor51.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
SlyX (PF04102, IPR007236): SlyX
DIX (PF00778, IPR001158, SM00021): DIX domain
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
40 DNAJA3suppressor30.6670.400DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
41 DOCK7interactor90.5831.648DHR-2 (PF06920, IPR010703): Dock homology region 2
DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
DOCK_N (PF16172, IPR032376): DOCK N-terminus
42 DSTNinteractor100.53314.605Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
43 EGFRoncoprotein250.268109.351Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
44 EIF3Binteractor50.6002.250eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal
PALB2_WD40 (PF16756, IPR031920): Partner and localizer of BRCA2 WD40 domain
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
45 EIF3Ioncoprotein80.4297.127ISN1 (PF06437, IPR009453): IMP-specific 5'-nucleotidase
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
46 EMDinteractor110.48910.509LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
47 ESR1suppressor360.235224.032Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
48 FARP1interactor50.6001.504FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
PH (PF00169, IPR001849, SM00233): PH domain
PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
49 FBXO30interactor100zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C2H2_4 (PF13894): C2H2-type zinc finger
DUF4644 (PF15486, IPR027978): Domain of unknown function (DUF4644)
zf-TRAF_2 (PF15965, IPR001293): TRAF-like zinc-finger
F-box_4 (PF15966, IPR001810): F-box
50 FBXO46interactor50.7001.833BTK (PF00779, IPR001562, SM00107): BTK motif
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
CHORD (PF04968, IPR007051): CHORD
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
F-box-like (PF12937, IPR001810): F-box-like
51 FLIIoncoprotein150.7712.259Gelsolin (PF00626, IPR007123): Gelsolin repeat
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
52 FLNAsuppressor650.314427.967CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
53 GAKoncoprotein100.6004.624DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
54 GIPC1interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
55 GRK5protein found in more fusions110.33310.392Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
56 GTF2F1interactor21.0000TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
57 HDGFRP2interactor40.6670.311DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
PWWP (PF00855, IPR000313, SM00293): PWWP domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF)
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
ACTH_assoc (PF16102, IPR032246): ACTH-associated domain
58 HMGB2interactor70.7143.516HMG_box_2 (PF09011, IPR009071): HMG-box domain
NOA36 (PF06524, IPR010531): NOA36 protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
59 HNRNPRinteractor150.51423.971RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
60 ILF3oncoprotein180.37344.879dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
61 IMPDH1interactor31.0000IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
62 IMPDH2protein found in more fusions90.5005.365IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
63 INF2interactor140.7914.777Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
64 IQCB1interactor60.6672.452DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
65 IQGAP1interactor630.290518.372CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
66 JMYinteractor21.0000WH2 (PF02205, IPR003124, SM00246): WH2 motif
Glyco_trans_1_2 (PF13524): Glycosyl transferases group 1
JMY (PF15871, IPR031738): Junction-mediating and -regulatory protein
WHAMM-JMY_N (PF15920, IPR031808): N-terminal of Junction-mediating and WASP homolog-associated
CALM_bind (PF16025): Calcium-dependent calmodulin binding
67 KAT2Bprotein found in more fusions80.4298.054Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
68 KDRoncoprotein50.7001.150Ehrlichia_rpt (PF09528, IPR019048): Ehrlichia tandem repeat (Ehrlichia_rpt)
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
69 KHDRBS1protein found in more fusions120.4369.871KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
70 KIF11protein found in more fusions70.5334.750Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
71 LARP4interactor40.6670.410La (PF05383, IPR006630, SM00715): La domain
SPATIAL (PF15256): SPATIAL
72 LIMA1suppressor560.358284.428LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
73 LRRK2oncoprotein120.6912.186Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
74 MCM5oncoprotein170.41939.702MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
75 MED12oncoprotein70.4765.116Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877)
Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain
Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
76 MED16interactor40.8330.080WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Med16 (PF11635, IPR021665): Mediator complex subunit 16
77 MEX3Cinteractor40.5001.233KH_1 (PF00013, IPR004088, SM00322): KH domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
78 MPRIPinteractor220.55018.474Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
Fez1 (PF06818): Fez1
FliT (PF05400, IPR008622): Flagellar protein FliT
HalX (PF08663, IPR013971): HalX domain
Mnd1 (PF03962, IPR005647): Mnd1 family
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
IFT57 (PF10498, IPR019530): Intra-flagellar transport protein 57
YlqD (PF11068, IPR021297): YlqD protein
DUF3015 (PF11220, IPR021383): Protein of unknown function (DUF3015)
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
79 MRM1interactor100SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family
SpoU_sub_bind (PF08032, IPR013123, SM00967): RNA 2'-O ribose methyltransferase substrate binding
80 MYH10interactor210.34844.512IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
81 MYH9suppressor770.253860.722IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
82 MYO18Ainteractor540.350241.784Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
83 MYO19interactor550.304316.085IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
84 MYO1Binteractor250.49730.053IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
AAA_23 (PF13476): AAA domain
85 MYO5Ainteractor170.7434.042DIL (PF01843, IPR018444, SM01132): DIL domain
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
SOGA (PF11365, IPR027881): Protein SOGA
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
CYTL1 (PF15153, IPR029253): Cytokine-like protein 1
86 NCBP3interactor31.0000Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
TLP-20 (PF06088, IPR009092): Nucleopolyhedrovirus telokin-like protein-20 (TLP20)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
87 NEK6interactor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
88 NEXNinteractor130.9360.355Cas_Csy4 (PF09618, IPR013396): CRISPR-associated protein (Cas_Csy4)
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain
DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951)
Med2 (PF11214, IPR021017): Mediator complex subunit 2
DUF2897 (PF11446, IPR021550): Protein of unknown function (DUF2897)
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355)
Casc1_N (PF15927, IPR031826): Cancer susceptibility candidate 1 N-terminus
Connexin40_C (PF16791, IPR031862): Connexin 40 C-terminal domain
89 NSRP1interactor21.0000Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
DUF2040 (PF09745, IPR018612): Coiled-coil domain-containing protein 55 (DUF2040)
Macoilin (PF09726, IPR019130): Transmembrane protein
PepSY_2 (PF13670, IPR025711): Peptidase propeptide and YPEB domain
90 NTRK1oncoprotein660.1341218.613I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
91 OXR1interactor21.0000GRAM (PF02893, IPR004182, SM00568): GRAM domain
LysM (PF01476, IPR018392, SM00257): LysM domain
TLD (PF07534, IPR006571, SM00584): TLD
DUF3350 (PF11830, IPR021785): Domain of unknown function (DUF3350)
92 PALLDinteractor100.4899.454I-set (PF07679, IPR013098): Immunoglobulin I-set domain
93 PAN2interactor390.301227.894RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
94 PDGFRAoncoprotein80.5246.917Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_3 (PF13927): Immunoglobulin domain
LAT (PF15234, IPR008359): Linker for activation of T-cells
95 PDLIM7interactor200.51117.606LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
96 PHLDB2interactor70.7624.000DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
PH (PF00169, IPR001849, SM00233): PH domain
Synaptobrevin (PF00957, IPR001388): Synaptobrevin
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
97 PLEKHG3interactor110.9820.048PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PH_10 (PF15411): Pleckstrin homology domain
98 PNPOinteractor100Pyridox_oxidase (PF01243, IPR011576): Pyridoxamine 5'-phosphate oxidase
PNPOx_C (PF10590, IPR019576): Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region
99 POLR1Binteractor70.5244.858RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain
RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
100 PPP1CAsuppressor210.64818.889Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
101 PPP1CBinteractor550.347299.921Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
102 PPP1R12Ainteractor200.60011.466DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
AAA_23 (PF13476): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
GEMIN8 (PF15348): Gemini of Cajal bodies-associated protein 8
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
103 PTENsuppressor170.36032.783DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
104 PYCARDsuppressor200CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
105 RAI14interactor200.63712.617Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Fez1 (PF06818): Fez1
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF2408 (PF10303, IPR018810): Protein of unknown function (DUF2408)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MscS_porin (PF12795, IPR024393): Mechanosensitive ion channel porin domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
AAA_13 (PF13166, IPR026866): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
106 RALAoncoprotein80.7501.307ArgK (PF03308, IPR005129): ArgK protein
Ras (PF00071, IPR001806, SM00173): Ras family
ThiF (PF00899, IPR000594): ThiF family
107 RBM10interactor110.5339.148G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
zf-C2H2_4 (PF13894): C2H2-type zinc finger
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
FAM176 (PF14851): FAM176 family
108 RBM17interactor40.5000.983G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
Slu7 (PF11708, IPR021715): Pre-mRNA splicing Prp18-interacting factor
109 RBM33interactor100IncA (PF04156, IPR007285): IncA protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
110 RBM5suppressor40.6670.917DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
111 RPA1suppressor360.371121.382Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
112 RPA2oncoprotein330.324117.359RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
113 RPA3interactor320.303115.082Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
114 RPS6KB2interactor50.5003.167Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
115 RRN3interactor30.6670.500RRN3 (PF05327, IPR007991): RNA polymerase I specific transcription initiation factor RRN3
116 SAFB2suppressor70.4296.451LicD (PF04991, IPR007074): LicD family
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
117 SCAF8interactor31.0000DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
DUF3525 (PF12039, IPR021912): Protein of unknown function (DUF3525)
YebO (PF13974, IPR025594): YebO-like protein
CNDH2_M (PF16869): PF16858
118 SEPT7interactor50.6001.575Fez1 (PF06818): Fez1
Septin (PF00735, IPR000038): Septin
119 SF3B1oncoprotein160.41734.317Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
120 SF3B2interactor120.43912.055DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382)
PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region
PSP (PF04046, IPR006568, SM00581): PSP
SAP (PF02037, IPR003034, SM00513): SAP domain
Usp (PF00582, IPR006016): Universal stress protein family
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
121 SHC1oncoprotein140.6158.803PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
122 SIPA1oncoprotein90.9720.048IncA (PF04156, IPR007285): IncA protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
123 SIPA1L3interactor81.0000IncA (PF04156, IPR007285): IncA protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein
124 SIRT7interactor300.207176.871DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
125 SMARCA5interactor140.35929.014HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DBINO (PF13892, IPR020838): DNA-binding domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
126 SORBS2oncoprotein160.62912.738Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
127 SP1protein found in more fusions120.5459.249zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Miga (PF10265, IPR019392): Mitoguardin
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
128 SPECC1oncoprotein130.9360.355CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Fez1 (PF06818): Fez1
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
SHE3 (PF17078, IPR031398): SWI5-dependent HO expression protein 3
129 SPTAN1oncoprotein360.387139.035EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
130 SPTBN1suppressor300.48550.506CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
131 SPTBN2interactor110.9270.588BEX (PF04538, IPR021156): Brain expressed X-linked like family
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Spectrin (PF00435, IPR002017): Spectrin repeat
Mating_N (PF12731, IPR024333): Mating-type protein beta 1
DUF4110 (PF13422, IPR025183): Domain of unknown function (DUF4110)
PH_9 (PF15410): Pleckstrin homology domain
132 SRSF2oncoprotein60.4001.585RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
133 SSFA2interactor130.6678.052KRAP_IP3R_bind (PF14722, IPR029325): Ki-ras-induced actin-interacting protein-IP3R-interacting domain
SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
134 SSH1interactor21.0000DEK_C (PF08766, IPR014876): DEK C terminal domain
DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
135 SUZ12suppressor180.23566.322DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
136 SVILinteractor200.7637.545Gelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
137 SYNPOinteractor510.368208.147Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
138 TADA3interactor50.7001.467GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF
Ada3 (PF10198, IPR019340): Histone acetyltransferases subunit 3
139 TIMM13interactor70.4767.220zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
140 TIMM8Binteractor21.0000zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
141 TJP1interactor120.5619.584DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal
142 TJP2oncoprotein60.7330.751PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
143 TMOD3interactor200.62122.619Tropomodulin (PF03250, IPR004934): Tropomodulin
Usher (PF00577, IPR000015): Outer membrane usher protein
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
144 TP53suppressor280.353111.795DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
145 TPRNinteractor140.9120.972DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
146 TRIOBPinteractor80.9640.048FadA (PF09403, IPR018543): Adhesion protein FadA
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PH (PF00169, IPR001849, SM00233): PH domain
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
147 TWF1interactor140.8462.888Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
148 TWF2interactor60.8001.400Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
149 U2SURPinteractor120.34822.297cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB)
Surp (PF01805, IPR000061, SM00648): Surp module
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
FAM176 (PF14851): FAM176 family
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637)
150 UBE2Q2interactor31.0000Josephin (PF02099, IPR006155): Josephin
RWD (PF05773, IPR006575, SM00591): RWD domain
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
DUF2890 (PF11081, IPR021304): Protein of unknown function (DUF2890)
151 UNC45Ainteractor90.5563.065Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
TPR_16 (PF13432): Tetratricopeptide repeat
HEAT_2 (PF13646): HEAT repeats
152 USP20protein found in more fusions200UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
DUSP (PF06337, IPR006615, SM00695): DUSP domain
153 UVRAGsuppressor100C2 (PF00168, IPR000008, SM00239): C2 domain
HTH_1 (PF00126, IPR000847): Bacterial regulatory helix-turn-helix protein, lysR family
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
154 WDR1interactor170.8384.254eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
155 WRAP73interactor50.5001.750eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
IKI3 (PF04762, IPR006849): IKI3 family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2555 (PF10742, IPR019678): Protein of unknown function (DUF2555)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
156 ZSCAN26interactor30.6670.111C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACTA1interactorActin (PF00022, IPR004000, SM00268): Actin
2 ACTA2interactorActin (PF00022, IPR004000, SM00268): Actin
3 ACTG1interactorActin (PF00022, IPR004000, SM00268): Actin
4 ARPC3interactorP21-Arc (PF04062, IPR007204): ARP2/3 complex ARPC3 (21 kDa) subunit
5 C19orf43interactorNA
6 C19orf52interactorDUF2366 (PF10171, IPR019322): Uncharacterised conserved protein (DUF2366)
7 CALM1interactorEF-hand_7 (PF13499, IPR011992): EF-hand domain pair
8 CYP19A1oncoproteinp450 (PF00067, IPR001128): Cytochrome P450
9 FBXO25suppressorElongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
10 KCTD10interactorBTB_2 (PF02214, IPR003131): BTB/POZ domain
11 MED15interactorMed15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
12 MISPinteractorAKAP2_C (PF15304, IPR029304): A-kinase anchor protein 2 C-terminus
13 MRPL55interactorMitoc_L55 (PF09776, IPR018615): Mitochondrial ribosomal protein L55
14 MYO1Cparental proteinIQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
15 PCNPinteractorPCNP (PF15473, IPR029169): PEST, proteolytic signal-containing nuclear protein family
16 RIOK3interactorRIO1 (PF01163, IPR018934): RIO1 family
17 SAP18interactorSAP18 (PF06487, IPR010516): Sin3 associated polypeptide p18 (SAP18)
18 SQRDLinteractorPyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
19 TMOD1interactorTropomodulin (PF03250, IPR004934): Tropomodulin
20 VCLoncoproteinVinculin (PF01044, IPR006077): Vinculin family

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