1 |
DA778521 | chimera | 341 | 0.051 | 69555.005 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
2 |
ACTA2 | interactor | 7 | 0.571 | 3.037 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ADAMTSL4 | interactor | 3 | 0.667 | 0.667 | ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1 PLAC (PF08686, IPR010909, SM00022): PLAC (protease and lacunin) domain TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type |
4 |
AES | protein found in more fusions | 22 | 0.167 | 135.243 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain |
5 |
AIRE | interactor | 18 | 0.375 | 26.997 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain |
6 |
AKT1 | oncoprotein | 42 | 0.255 | 240.891 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
7 |
AMOTL2 | protein found in more fusions | 13 | 0.227 | 40.467 | HOOK (PF05622, IPR008636): HOOK protein SlyX (PF04102, IPR007236): SlyX Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
8 |
ANAPC2 | interactor | 12 | 0.652 | 8.144 | ANAPC2 (PF08672, IPR014786, SM01013): Anaphase promoting complex (APC) subunit 2 Cullin (PF00888, IPR001373, SM00182): Cullin family |
9 |
ANAPC5 | interactor | 12 | 0.697 | 6.419 | TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
10 |
ANAPC7 | interactor | 12 | 0.764 | 3.452 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
11 |
APC | suppressor | 14 | 0.282 | 31.798 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
12 |
APP | protein found in more fusions | 56 | 0.115 | 842.275 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
13 |
AR | oncoprotein | 53 | 0.293 | 305.622 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
14 |
ARIH1 | protein found in more fusions | 5 | 0.500 | 0.889 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain Med14 (PF08638, IPR013947): Mediator complex subunit MED14 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
15 |
ARNTL | suppressor | 10 | 0.578 | 8.813 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain |
16 |
ATF1 | oncoprotein | 7 | 0.619 | 2.341 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
17 |
ATF2 | oncoprotein | 30 | 0.340 | 88.547 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
18 |
ATF3 | suppressor | 25 | 0.431 | 39.408 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
19 |
ATF4 | oncoprotein | 19 | 0.444 | 37.973 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
20 |
ATG3 | interactor | 3 | 1.000 | 0 | Autophagy_C (PF10381, IPR019461): Autophagocytosis associated protein C-terminal Autophagy_N (PF03986, IPR007134): Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C (PF03987, IPR007135): Autophagocytosis associated protein, active-site domain |
21 |
ATXN3 | interactor | 21 | 0.247 | 70.067 | Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
22 |
BCL6 | oncoprotein | 24 | 0.304 | 90.539 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
23 |
BMI1 | oncoprotein | 23 | 0.333 | 57.822 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
24 |
BRCA1 | suppressor | 59 | 0.285 | 394.762 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
25 |
BRMS1 | suppressor | 14 | 0.513 | 9.674 | Dynactin_p62 (PF05502, IPR008603): Dynactin p62 family Sds3 (PF08598, IPR013907): Sds3-like |
26 |
C3orf62 | interactor | 3 | 0.667 | 0.061 | DUF4712 (PF15830, IPR031670): Domain of unknown function (DUF4712) |
27 |
CARD9 | interactor | 11 | 0.311 | 22.567 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper IncA (PF04156, IPR007285): IncA protein NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein |
28 |
CARM1 | oncoprotein | 26 | 0.366 | 56.299 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
29 |
CCNA2 | oncoprotein | 22 | 0.410 | 65.052 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N |
30 |
CCNC | suppressor | 9 | 0.500 | 15.300 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain |
31 |
CCND3 | oncoprotein | 9 | 0.417 | 6.223 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
32 |
CCNE1 | oncoprotein | 16 | 0.383 | 27.681 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
33 |
CDC16 | interactor | 13 | 0.603 | 13.735 | Dynein_light (PF01221, IPR001372): Dynein light chain type 1 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat |
34 |
CDC20 | oncoprotein | 28 | 0.305 | 134.666 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
35 |
CDC27 | oncoprotein | 22 | 0.362 | 58.547 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat |
36 |
CDH1 | suppressor | 12 | 0.491 | 10.316 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
37 |
CDH2 | interactor | 3 | 1.000 | 0 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain Cadherin_3 (PF16184): Cadherin-like |
38 |
CDK2 | suppressor | 51 | 0.233 | 434.316 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
39 |
CDK8 | interactor | 26 | 0.417 | 61.042 | Pkinase (PF00069, IPR000719): Protein kinase domain |
40 |
CDKN1A | suppressor | 44 | 0.244 | 335.497 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
41 |
CDR2 | interactor | 6 | 0.500 | 2.533 | DivIC (PF04977, IPR007060): Septum formation initiator SlyX (PF04102, IPR007236): SlyX Striatin (PF08232, IPR013258): Striatin family BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) |
42 |
CEBPB | oncoprotein | 43 | 0.347 | 147.284 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
43 |
CEBPD | suppressor | 14 | 0.484 | 19.552 | bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
44 |
CENPJ | interactor | 5 | 0.500 | 2.733 | DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus TSC22 (PF01166, IPR000580): TSC-22/dip/bun family AAA_23 (PF13476): AAA domain DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |
45 |
CHUK | suppressor | 28 | 0.422 | 63.270 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
46 |
CITED1 | interactor | 6 | 0.667 | 2.650 | CITED (PF04487, IPR007576): CITED |
47 |
CITED2 | suppressor | 8 | 0.536 | 4.448 | CITED (PF04487, IPR007576): CITED |
48 |
CLOCK | interactor | 6 | 1.000 | 0 | DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PAS (PF00989, IPR013767, SM00091): PAS fold RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 PAS_11 (PF14598): PAS domain FlgT_N (PF16548, IPR032370): Flagellar assembly protein T, N-terminal domain |
49 |
COPS2 | suppressor | 15 | 0.419 | 20.817 | YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat |
50 |
CPSF6 | interactor | 9 | 0.444 | 6.338 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
51 |
CREB1 | oncoprotein | 38 | 0.266 | 227.481 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
52 |
CREM | suppressor | 7 | 0.571 | 2.585 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987) |
53 |
CRTC1 | oncoprotein | 6 | 0.533 | 3.436 | TORC_N (PF12884, IPR024783): Transducer of regulated CREB activity, N terminus TORC_M (PF12885, IPR024784): Transducer of regulated CREB activity middle domain TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus |
54 |
CSNK2A1 | oncoprotein | 45 | 0.204 | 381.953 | Pkinase (PF00069, IPR000719): Protein kinase domain |
55 |
CSNK2A2 | interactor | 14 | 0.308 | 29.516 | Pkinase (PF00069, IPR000719): Protein kinase domain |
56 |
CTBP1 | protein found in more fusions | 32 | 0.318 | 109.245 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
57 |
CTNNB1 | oncoprotein | 58 | 0.199 | 616.844 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
58 |
CUX1 | suppressor | 4 | 0.500 | 2.167 | Baculo_p24 (PF05073, IPR007765): Baculovirus P24 capsid protein CUT (PF02376, IPR003350, SM01109): CUT domain DegS (PF05384, IPR008595): Sensor protein DegS DivIC (PF04977, IPR007060): Septum formation initiator DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Swi5 (PF07061, IPR010760): Swi5 TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein ApoO (PF09769, IPR019166): Apolipoprotein O Homeobox (PF00046, IPR001356, SM00389): Homeobox domain RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
59 |
DAXX | oncoprotein | 37 | 0.267 | 175.016 | Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) |
60 |
DDIT3 | oncoprotein | 17 | 0.467 | 30.598 | IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
61 |
DDX17 | protein found in more fusions | 24 | 0.411 | 40.162 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
62 |
DDX5 | oncoprotein | 30 | 0.365 | 88.825 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
63 |
DEK | oncoprotein | 15 | 0.476 | 12.434 | DEK_C (PF08766, IPR014876): DEK C terminal domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family SAP (PF02037, IPR003034, SM00513): SAP domain Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
64 |
DYRK1A | oncoprotein | 17 | 0.325 | 32.771 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X |
65 |
DYRK1B | oncoprotein | 9 | 0.429 | 8.032 | Pkinase (PF00069, IPR000719): Protein kinase domain |
66 |
E2F1 | suppressor | 34 | 0.319 | 144.636 | Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
67 |
E2F3 | suppressor | 10 | 0.311 | 11.419 | E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
68 |
EBF1 | oncoprotein | 4 | 0.667 | 0.667 | TIG (PF01833, IPR002909): IPT/TIG domain COE1_DBD (PF16422, IPR032200): Transcription factor COE1 DNA-binding domain COE1_HLH (PF16423, IPR032201): Transcription factor COE1 helix-loop-helix domain |
69 |
EGR1 | suppressor | 11 | 0.564 | 6.261 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432) DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
70 |
EID3 | interactor | 4 | 0.667 | 0.667 | Nse4_C (PF08743, IPR014854): Nse4 C-terminal Nse4-Nse3_bdg (PF15412, IPR029225): Binding domain of Nse4/EID3 to Nse3-MAGE |
71 |
EIF3F | suppressor | 5 | 0.700 | 0.804 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
72 |
ELAVL1 | oncoprotein | 67 | 0.119 | 1071.767 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
73 |
ELK1 | oncoprotein | 14 | 0.333 | 20.528 | Ets (PF00178, IPR000418, SM00413): Ets-domain Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain |
74 |
EP300 | oncoprotein | 176 | 0.097 | 8628.522 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
75 |
EPAS1 | suppressor | 20 | 0.380 | 38.071 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
76 |
ESR1 | suppressor | 85 | 0.208 | 1195.338 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
77 |
ESR2 | suppressor | 25 | 0.333 | 66.870 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
78 |
ETS1 | oncoprotein | 25 | 0.427 | 55.131 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
79 |
ETS2 | suppressor | 12 | 0.697 | 3.172 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
80 |
EWSR1 | oncoprotein | 42 | 0.195 | 333.379 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
81 |
FAM58A | interactor | 2 | 1.000 | 0 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
82 |
FBXO25 | suppressor | 10 | 0.222 | 21.061 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A |
83 |
FBXW11 | interactor | 22 | 0.205 | 107.448 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
84 |
FERMT3 | interactor | 3 | 0.667 | 0.500 | FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
85 |
FGFR1 | oncoprotein | 8 | 0.429 | 6.327 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
86 |
FHL1 | suppressor | 11 | 0.709 | 3.214 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif |
87 |
FHL2 | oncoprotein | 28 | 0.356 | 73.721 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain |
88 |
FOS | oncoprotein | 38 | 0.288 | 189.610 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
89 |
FOSB | oncoprotein | 4 | 1.000 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Motilin_ghrelin (PF04644, IPR006738): Motilin/ghrelin |
90 |
FOSL1 | oncoprotein | 11 | 0.673 | 4.208 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
91 |
FOXM1 | oncoprotein | 9 | 0.444 | 6.569 | EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
92 |
FOXO1 | suppressor | 24 | 0.395 | 57.765 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
93 |
FOXO3 | suppressor | 22 | 0.446 | 37.417 | Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
94 |
FOXO4 | suppressor | 13 | 0.513 | 11.315 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
95 |
GATA1 | oncoprotein | 10 | 0.578 | 9.272 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
96 |
GCM1 | interactor | 4 | 0.667 | 0.126 | DUF1272 (PF06906, IPR010696): Protein of unknown function (DUF1272) GCM (PF03615, IPR003902): GCM motif protein |
97 |
GIGYF2 | interactor | 13 | 0.308 | 31.749 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
98 |
GLI3 | oncoprotein | 4 | 0.667 | 0.650 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
99 |
GRIP1 | protein found in more fusions | 16 | 0.571 | 9.837 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
100 |
GTF2B | interactor | 18 | 0.392 | 36.892 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding |
101 |
HBP1 | suppressor | 8 | 0.607 | 2.635 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
102 |
HCK | oncoprotein | 9 | 0.500 | 8.682 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
103 |
HDAC1 | suppressor | 99 | 0.173 | 1889.731 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
104 |
HDAC2 | suppressor | 63 | 0.221 | 533.913 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
105 |
HDAC3 | suppressor | 53 | 0.244 | 334.686 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
106 |
HES6 | interactor | 1 | 0 | 0 | Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
107 |
HIF1A | suppressor | 35 | 0.445 | 84.500 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
108 |
HIPK2 | suppressor | 23 | 0.307 | 91.547 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
109 |
HIST1H2BB | interactor | 11 | 0.491 | 8.104 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
110 |
HIST1H3A | interactor | 35 | 0.266 | 172.553 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
111 |
HIST1H4A | interactor | 28 | 0.315 | 84.927 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
112 |
HIST2H2BE | interactor | 18 | 0.366 | 36.188 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
113 |
HIST3H3 | interactor | 28 | 0.288 | 113.740 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
114 |
HIST4H4 | interactor | 13 | 0.474 | 9.028 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
115 |
HMGA1 | oncoprotein | 23 | 0.391 | 44.607 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
116 |
HMGB1 | oncoprotein | 20 | 0.284 | 69.862 | HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
117 |
HMGB2 | protein found in more fusions | 8 | 0.500 | 2.920 | HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
118 |
HNF1A | oncoprotein | 14 | 0.346 | 24.410 | HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
119 |
HNF4A | suppressor | 29 | 0.344 | 73.113 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
120 |
HOMEZ | interactor | 4 | 0.500 | 2.333 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Homez (PF11569, IPR024578): Homeodomain leucine-zipper encoding, Homez WRNPLPNID (PF15017): Putative WW-binding domain and destruction box PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
121 |
HOXA10 | interactor | 3 | 0.667 | 0.400 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266) |
122 |
HOXA9 | oncoprotein | 5 | 0.500 | 2.377 | Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
123 |
HOXB2 | interactor | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
124 |
HOXB3 | interactor | 2 | 1.000 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4074 (PF13293, IPR025281): Domain of unknown function (DUF4074) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
125 |
HOXB4 | interactor | 1 | 0 | 0 | DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) |
126 |
HOXB6 | interactor | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
127 |
HOXB7 | interactor | 5 | 0.500 | 1.971 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
128 |
HOXB9 | interactor | 4 | 0.500 | 1.567 | Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
129 |
HOXD10 | interactor | 3 | 0.667 | 0.154 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
130 |
HOXD12 | interactor | 3 | 0.667 | 0.500 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
131 |
HOXD13 | oncoprotein | 5 | 0.600 | 1.011 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal |
132 |
HOXD4 | interactor | 5 | 0.600 | 1.519 | SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus |
133 |
HSF1 | protein found in more fusions | 16 | 0.381 | 16.664 | DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
134 |
HTT | protein found in more fusions | 20 | 0.368 | 32.841 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
135 |
HUWE1 | oncoprotein | 39 | 0.174 | 303.008 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
136 |
IFNAR2 | interactor | 5 | 1.000 | 0 | Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor |
137 |
IKBKB | protein found in more fusions | 18 | 0.426 | 23.729 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
138 |
IKBKG | interactor | 18 | 0.331 | 34.788 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
139 |
ING1 | suppressor | 19 | 0.433 | 27.913 | PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta |
140 |
IRF1 | suppressor | 10 | 0.533 | 7.932 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor |
141 |
IRF3 | suppressor | 15 | 0.440 | 24.556 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
142 |
IRF5 | suppressor | 11 | 0.511 | 6.096 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
143 |
IRF7 | interactor | 10 | 0.611 | 3.694 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
144 |
IRF9 | interactor | 7 | 0.571 | 4.629 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
145 |
JUN | oncoprotein | 72 | 0.233 | 877.085 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
146 |
JUNB | oncoprotein | 16 | 0.400 | 26.632 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
147 |
KAT2B | protein found in more fusions | 75 | 0.154 | 1175.789 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
148 |
KAT5 | suppressor | 42 | 0.270 | 246.011 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
149 |
KAT6A | oncoprotein | 15 | 0.419 | 14.940 | BUD22 (PF09073, IPR015158): BUD22 MOZ_SAS (PF01853, IPR002717): MOZ/SAS family PHD (PF00628, IPR019787, SM00249): PHD-finger Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) zf-met (PF12874): Zinc-finger of C2H2 type |
150 |
KDM3B | suppressor | 5 | 0.500 | 1.606 | JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger |
151 |
KHDRBS1 | protein found in more fusions | 17 | 0.300 | 42.776 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
152 |
KLF1 | interactor | 7 | 0.571 | 2.520 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain EKLF_TAD1 (PF16832, IPR031786): Erythroid krueppel-like transcription factor, transactivation 1 EKLF_TAD2 (PF16833, IPR031784): Erythroid krueppel-like transcription factor, transactivation 2 |
153 |
KLF13 | interactor | 5 | 0.800 | 0.650 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
154 |
KLF2 | interactor | 5 | 0.500 | 1.118 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
155 |
KLF4 | suppressor | 13 | 0.577 | 7.686 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
156 |
KLF5 | suppressor | 24 | 0.500 | 25.582 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
157 |
KLF8 | interactor | 7 | 0.524 | 1.467 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
158 |
KMT2A | oncoprotein | 24 | 0.372 | 50.763 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
159 |
KPNA2 | interactor | 23 | 0.225 | 117.136 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
160 |
KPNA6 | interactor | 8 | 0.250 | 11.193 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
161 |
KRT13 | interactor | 5 | 0.400 | 4.167 | Filament (PF00038, IPR001664): Intermediate filament protein FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus Keratin_2_head (PF16208, IPR032444): Keratin type II head |
162 |
KRT19 | suppressor | 8 | 0.381 | 8.567 | Filament (PF00038, IPR001664): Intermediate filament protein |
163 |
KRT31 | interactor | 9 | 0.306 | 17.983 | Filament (PF00038, IPR001664): Intermediate filament protein |
164 |
KRTAP10-5 | interactor | 7 | 0.400 | 8.000 | Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
165 |
KRTAP10-8 | interactor | 5 | 0.667 | 1.667 | Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein PMG (PF05287, IPR007951): PMG protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
166 |
LDLR | interactor | 1 | 0 | 0 | EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B hEGF (PF12661, IPR013032): Human growth factor-like EGF FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
167 |
LIG4 | interactor | 3 | 0.667 | 0.333 | APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
168 |
LYN | oncoprotein | 14 | 0.397 | 18.185 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
169 |
LZTS2 | suppressor | 11 | 0.200 | 31.706 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127) Fez1 (PF06818): Fez1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250) |
170 |
MAF | oncoprotein | 13 | 0.424 | 17.933 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen TraT (PF05818, IPR008874): Enterobacterial TraT complement resistance protein Metal_resist (PF13801, IPR025961): Heavy-metal resistance |
171 |
MAFK | oncoprotein | 12 | 0.561 | 13.285 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
172 |
MAGED1 | protein found in more fusions | 9 | 0.393 | 7.076 | MAGE (PF01454, IPR002190): MAGE family |
173 |
MAML1 | interactor | 8 | 0.393 | 6.692 | MamL-1 (PF09596, IPR019082): MamL-1 domain Kri1 (PF05178, IPR018034): KRI1-like family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
174 |
MAML2 | oncoprotein | 3 | 1.000 | 0 | Senescence_reg (PF04520, IPR007608): Senescence regulator BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal MamL-1 (PF09596, IPR019082): MamL-1 domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
175 |
MAP3K5 | oncoprotein | 11 | 0.444 | 7.792 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
176 |
MAPK1 | oncoprotein | 42 | 0.270 | 267.773 | Pkinase (PF00069, IPR000719): Protein kinase domain |
177 |
MAPK10 | suppressor | 10 | 0.556 | 3.019 | Pkinase (PF00069, IPR000719): Protein kinase domain |
178 |
MAPK3 | oncoprotein | 27 | 0.240 | 140.640 | Pkinase (PF00069, IPR000719): Protein kinase domain |
179 |
MAPRE3 | interactor | 2 | 1.000 | 0 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif |
180 |
MDC1 | suppressor | 18 | 0.399 | 43.037 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
181 |
MDFI | interactor | 11 | 0.267 | 24.034 | MDFI (PF15316, IPR026134): MyoD family inhibitor |
182 |
MDM2 | oncoprotein | 65 | 0.205 | 667.820 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
183 |
MECOM | oncoprotein | 11 | 0.582 | 4.050 | SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
184 |
MED21 | protein found in more fusions | 21 | 0.374 | 45.820 | Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex |
185 |
MED23 | interactor | 33 | 0.267 | 170.222 | Med23 (PF11573, IPR021629): Mediator complex subunit 23 |
186 |
MED25 | interactor | 11 | 0.467 | 7.494 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A |
187 |
MEIS1 | oncoprotein | 6 | 0.467 | 5.200 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Meis_PKNOX_N (PF16493, IPR032453): N-terminal of Homeobox Meis and PKNOX1 |
188 |
MGMT | interactor | 13 | 0.487 | 12.253 | DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain |
189 |
MIER1 | oncoprotein | 6 | 0.600 | 1.047 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain ELM2 (PF01448, IPR000949): ELM2 domain HpaP (PF09483, IPR013390): Type III secretion protein (HpaP) SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein |
190 |
MIPOL1 | interactor | 2 | 0 | 0 | Bac_globin (PF01152, IPR001486): Bacterial-like globin CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003) ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Rho_Binding (PF08912, IPR015008): Rho Binding IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D |
191 |
MKNK1 | interactor | 8 | 0.321 | 6.809 | Pkinase (PF00069, IPR000719): Protein kinase domain |
192 |
MSH2 | suppressor | 17 | 0.483 | 20.945 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain |
193 |
MSH6 | oncoprotein | 11 | 0.636 | 8.585 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II PWWP (PF00855, IPR000313, SM00293): PWWP domain MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70 |
194 |
MSX1 | protein found in more fusions | 4 | 1.000 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
195 |
MTDH | interactor | 4 | 0.833 | 0.083 | NST1 (PF13945, IPR025279): Salt tolerance down-regulator NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain LYRIC (PF15686, IPR031402): Lysine-rich CEACAM1 co-isolated protein family |
196 |
MTF1 | interactor | 2 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Marek_A (PF02124, IPR001038): Marek's disease glycoprotein A zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
197 |
MUS81 | suppressor | 5 | 0.400 | 5.000 | ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MutL (PF13941, IPR006230): MutL protein HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain |
198 |
MYB | oncoprotein | 19 | 0.327 | 43.231 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
199 |
MYBL1 | oncoprotein | 3 | 1.000 | 0 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
200 |
MYBL2 | oncoprotein | 14 | 0.359 | 26.227 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
201 |
MYC | oncoprotein | 65 | 0.259 | 566.087 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
202 |
MYH9 | suppressor | 16 | 0.317 | 40.554 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
203 |
MYOD1 | oncoprotein | 26 | 0.347 | 65.084 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5 |
204 |
MYOG | interactor | 12 | 0.288 | 28.440 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
205 |
N4BP2 | interactor | 4 | 1.000 | 0 | CUE (PF02845, IPR003892, SM00546): CUE domain DUF1771 (PF08590, IPR013899, SM01162): Domain of unknown function (DUF1771) RyR (PF02026, IPR003032): RyR domain Smr (PF01713, IPR002625, SM00463): Smr domain AAA_22 (PF13401, IPR003593): AAA domain AAA_33 (PF13671): AAA domain |
206 |
NCOA1 | oncoprotein | 39 | 0.353 | 145.823 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
207 |
NCOA2 | oncoprotein | 25 | 0.393 | 58.309 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
208 |
NCOA3 | oncoprotein | 41 | 0.306 | 205.038 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
209 |
NCOA6 | oncoprotein | 33 | 0.373 | 86.823 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
210 |
NCOR1 | oncoprotein | 48 | 0.301 | 246.559 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
211 |
NCOR2 | oncoprotein | 37 | 0.414 | 89.093 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
212 |
NEUROG1 | interactor | 4 | 0.833 | 0.500 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Transformer (PF06495, IPR010519): Fruit fly transformer protein |
213 |
NFATC2 | suppressor | 5 | 1.000 | 0 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
214 |
NFATC4 | interactor | 2 | 1.000 | 0 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
215 |
NFE2 | interactor | 5 | 0.833 | 0.222 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Peptidase_Mx (PF15887, IPR031321): Putative zinc-binding metallo-peptidase |
216 |
NFE2L2 | oncoprotein | 19 | 0.409 | 38.269 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
217 |
NFYB | interactor | 13 | 0.654 | 7.202 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone |
218 |
NKX2-1 | oncoprotein | 7 | 0.619 | 2.098 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4719 (PF15843, IPR031696): Domain of unknown function (DUF4719) |
219 |
NLK | protein found in more fusions | 16 | 0.333 | 38.669 | Pkinase (PF00069, IPR000719): Protein kinase domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
220 |
NOTCH2NL | interactor | 8 | 0.321 | 14.233 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like |
221 |
NPAS2 | suppressor | 7 | 0.905 | 0.800 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold DehI (PF10778, IPR019714): Halocarboxylic acid dehydrogenase DehI PAS_11 (PF14598): PAS domain |
222 |
NPAT | interactor | 5 | 0.500 | 2.786 | Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 NPAT_C (PF15712, IPR031442): NPAT C terminus |
223 |
NR3C1 | protein found in more fusions | 46 | 0.282 | 305.138 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
224 |
NR3C2 | oncoprotein | 7 | 0.619 | 1.436 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
225 |
NR5A1 | interactor | 9 | 0.444 | 5.308 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
226 |
NUP98 | suppressor | 8 | 0.536 | 4.296 | Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
227 |
ONECUT1 | suppressor | 3 | 0.667 | 0.154 | CUT (PF02376, IPR003350, SM01109): CUT domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
228 |
PAPOLA | interactor | 8 | 0.321 | 6.227 | PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain Macoilin (PF09726, IPR019130): Transmembrane protein |
229 |
PARP1 | suppressor | 48 | 0.278 | 310.981 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
230 |
PBX1 | oncoprotein | 13 | 0.295 | 36.610 | PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
231 |
PCNA | oncoprotein | 36 | 0.261 | 204.405 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
232 |
PELP1 | interactor | 14 | 0.429 | 16.186 | RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis NUC202 (PF08166, IPR012980): NUC202 domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) |
233 |
PHOX2A | suppressor | 4 | 1.000 | 0 | Phage_Mu_Gam (PF07352, IPR009951): Bacteriophage Mu Gam like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
234 |
PHOX2B | oncoprotein | 1 | 0 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TraC (PF07820, IPR012930): TraC-like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
235 |
PIAS3 | oncoprotein | 14 | 0.451 | 15.697 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
236 |
PLAGL1 | suppressor | 10 | 0.778 | 1.083 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
237 |
PML | suppressor | 53 | 0.261 | 360.782 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
238 |
POLR2A | protein found in more fusions | 37 | 0.281 | 159.010 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
239 |
POT1 | interactor | 8 | 0.381 | 7.427 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
240 |
POU1F1 | interactor | 7 | 0.714 | 1.372 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2 |
241 |
POU2F3 | suppressor | 2 | 1.000 | 0 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
242 |
PPARG | suppressor | 42 | 0.339 | 170.991 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
243 |
PPARGC1A | interactor | 17 | 0.522 | 13.614 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
244 |
PPP1R13L | oncoprotein | 7 | 0.619 | 3.516 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SH3_9 (PF14604, IPR001452): Variant SH3 domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
245 |
PRDM14 | interactor | 1 | 0 | 0 | Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
246 |
PRLR | oncoprotein | 3 | 1.000 | 0 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
247 |
PSMC5 | protein found in more fusions | 27 | 0.274 | 97.337 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
248 |
PSME3 | protein found in more fusions | 15 | 0.363 | 28.444 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
249 |
PTMA | oncoprotein | 12 | 0.424 | 10.054 | Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family |
250 |
PTMS | interactor | 7 | 0.429 | 3.616 | Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 |
251 |
PTOV1 | interactor | 1 | 0 | 0 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 |
252 |
PTTG1 | oncoprotein | 12 | 0.345 | 20.147 | Securin (PF04856, IPR006940): Securin sister-chromatid separation inhibitor |
253 |
PYGO2 | interactor | 5 | 0.667 | 0.348 | PHD (PF00628, IPR019787, SM00249): PHD-finger |
254 |
RAD23A | oncoprotein | 13 | 0.470 | 13.383 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
255 |
RARA | oncoprotein | 36 | 0.271 | 169.997 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
256 |
RBBP4 | oncoprotein | 30 | 0.375 | 88.762 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
257 |
RBBP7 | suppressor | 20 | 0.432 | 48.035 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
258 |
REL | oncoprotein | 14 | 0.407 | 20.714 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
259 |
RELA | oncoprotein | 69 | 0.218 | 810.539 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
260 |
RPA2 | oncoprotein | 23 | 0.277 | 90.719 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
261 |
RPS6KA1 | oncoprotein | 9 | 0.444 | 10.013 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
262 |
RPS6KA2 | suppressor | 7 | 0.800 | 1.119 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
263 |
RPS6KA3 | interactor | 7 | 0.524 | 6.061 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
264 |
RPS6KA5 | interactor | 14 | 0.363 | 27.153 | Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
265 |
RUNX1 | suppressor | 31 | 0.372 | 81.481 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
266 |
RUNX2 | suppressor | 17 | 0.596 | 8.959 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) |
267 |
RUVBL1 | oncoprotein | 19 | 0.373 | 31.629 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
268 |
SERTAD1 | interactor | 6 | 0.533 | 2.710 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal SERTA (PF06031, IPR009263): SERTA motif |
269 |
SETD1A | interactor | 6 | 0.733 | 0.644 | E7 (PF00527, IPR000148): E7 protein, Early protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET (PF00856, IPR001214, SM00317): SET domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632) DUF4667 (PF15700, IPR031426): Domain of unknown function (DUF4667) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
270 |
SH3GL1 | oncoprotein | 5 | 0.667 | 0.722 | BAR (PF03114, IPR004148, SM00721): BAR domain PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
271 |
SMAD1 | interactor | 27 | 0.317 | 105.443 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
272 |
SMAD2 | suppressor | 47 | 0.274 | 292.466 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
273 |
SMAD3 | oncoprotein | 71 | 0.240 | 694.212 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
274 |
SMAD4 | suppressor | 41 | 0.291 | 208.185 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
275 |
SMARCA2 | suppressor | 32 | 0.401 | 83.449 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
276 |
SMARCA4 | suppressor | 62 | 0.233 | 558.419 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
277 |
SMARCB1 | suppressor | 32 | 0.316 | 121.128 | SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1 |
278 |
SNAI1 | oncoprotein | 15 | 0.438 | 31.205 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
279 |
SND1 | interactor | 11 | 0.400 | 8.719 | TUDOR (PF00567, IPR002999, SM00333): Tudor domain SNase (PF00565, IPR016071, SM00318): Staphylococcal nuclease homologue |
280 |
SNIP1 | interactor | 8 | 0.643 | 5.890 | FHA (PF00498, IPR000253, SM00240): FHA domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 FAM176 (PF14851): FAM176 family |
281 |
SP1 | protein found in more fusions | 65 | 0.249 | 651.444 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
282 |
SP3 | interactor | 12 | 0.773 | 2.106 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
283 |
SPAG5 | interactor | 3 | 0.667 | 0.667 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF1307 (PF06998, IPR009736): Protein of unknown function (DUF1307) DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
284 |
SRC | oncoprotein | 28 | 0.291 | 101.983 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
285 |
SRCAP | interactor | 7 | 0.667 | 1.292 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif HSA (PF07529, IPR014012, SM00573): HSA RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
286 |
SREBF1 | interactor | 17 | 0.417 | 26.279 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
287 |
SREBF2 | protein found in more fusions | 16 | 0.438 | 26.839 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
288 |
SRF | interactor | 22 | 0.324 | 46.079 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) |
289 |
SS18L1 | oncoprotein | 10 | 0.611 | 2.613 | DUF1313 (PF07011, IPR009741): Protein of unknown function (DUF1313) SSXT (PF05030, IPR007726): SSXT protein (N-terminal region) |
290 |
STAT1 | suppressor | 27 | 0.378 | 77.455 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
291 |
STAT2 | oncoprotein | 10 | 0.444 | 9.962 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal |
292 |
STAT3 | suppressor | 43 | 0.286 | 237.848 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
293 |
STAT6 | oncoprotein | 13 | 0.462 | 16.415 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT6_C (PF14596, IPR028187): STAT6 C-terminal |
294 |
TACC2 | interactor | 4 | 0.833 | 0.100 | TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC) |
295 |
TADA2A | interactor | 20 | 0.337 | 44.769 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
296 |
TAF6L | interactor | 5 | 0.600 | 2.686 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF) |
297 |
TBP | interactor | 41 | 0.306 | 208.006 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
298 |
TBX21 | oncoprotein | 3 | 1.000 | 0 | T-box (PF00907, IPR001699, SM00425): T-box T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated |
299 |
TCF12 | oncoprotein | 13 | 0.561 | 8.248 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
300 |
TCF3 | suppressor | 19 | 0.399 | 27.178 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
301 |
TCF4 | suppressor | 17 | 0.353 | 33.025 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
302 |
TDG | interactor | 17 | 0.441 | 16.466 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily |
303 |
TFAP2B | interactor | 5 | 0.500 | 2.317 | TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 |
304 |
TFDP1 | oncoprotein | 9 | 0.528 | 6.281 | DP (PF08781, IPR014889, SM01138): Transcription factor DP E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain |
305 |
TGS1 | interactor | 5 | 0.700 | 0.418 | DinI (PF06183, IPR010391): DinI-like family DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Methyltransf_15 (PF09445, IPR019012): RNA cap guanine-N2 methyltransferase Presenilin (PF01080, IPR001108): Presenilin |
306 |
TLE3 | interactor | 6 | 0.400 | 2.337 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
307 |
TLR2 | interactor | 3 | 1.000 | 0 | LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
308 |
TMCC2 | protein found in more fusions | 7 | 0.467 | 5.067 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
309 |
TP53 | suppressor | 111 | 0.160 | 2462.530 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
310 |
TP73 | suppressor | 26 | 0.403 | 62.846 | P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
311 |
TRAF6 | protein found in more fusions | 26 | 0.237 | 112.283 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
312 |
TRERF1 | interactor | 5 | 0.600 | 0.704 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal ELM2 (PF01448, IPR000949): ELM2 domain Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2681 (PF10883, IPR020274): Protein of unknown function (DUF2681) MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
313 |
TRIM27 | oncoprotein | 19 | 0.327 | 50.018 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
314 |
TRIM28 | protein found in more fusions | 36 | 0.255 | 182.632 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
315 |
TRIM54 | interactor | 11 | 0.289 | 19.223 | DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) zf-HIT (PF04438, IPR007529): HIT zinc finger zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
316 |
TRIP4 | interactor | 14 | 0.538 | 10.334 | ASCH (PF04266, IPR007374, SM01022): ASCH domain UxaC (PF02614, IPR003766): Glucuronate isomerase zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type |
317 |
TUBGCP3 | interactor | 8 | 0.464 | 4.895 | Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family |
318 |
TXNDC11 | interactor | 3 | 0.667 | 0.500 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
319 |
UBE2D1 | interactor | 18 | 0.338 | 35.332 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
320 |
UBE2I | interactor | 74 | 0.183 | 982.743 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
321 |
UBE2L3 | interactor | 17 | 0.317 | 35.809 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
322 |
UBE2S | interactor | 11 | 0.578 | 14.067 | ALF (PF03752, IPR005506): Short repeats of unknown function UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
323 |
UBXN11 | interactor | 3 | 0.667 | 0.667 | DivIC (PF04977, IPR007060): Septum formation initiator SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) TRPM_tetra (PF16519, IPR032415): Tetramerisation domain of TRPM |
324 |
USHBP1 | interactor | 7 | 0.400 | 7.167 | DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper SlyX (PF04102, IPR007236): SlyX MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome YlqD (PF11068, IPR021297): YlqD protein DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) CAGE1 (PF15066, IPR029381): Cancer-associated gene protein 1 family TEX13 (PF15186, IPR028193): Testis-expressed sequence 13 protein family |
325 |
USP4 | oncoprotein | 13 | 0.409 | 16.177 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
326 |
USP54 | interactor | 3 | 1.000 | 0 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase |
327 |
VDR | suppressor | 36 | 0.329 | 135.412 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
328 |
WDR5 | interactor | 27 | 0.274 | 108.851 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
329 |
WDR83 | interactor | 6 | 0.400 | 6.733 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
330 |
WRN | oncoprotein | 12 | 0.473 | 17.002 | DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease DEAD (PF00270, IPR011545): DEAD/DEAH box helicase HRDC (PF00570, IPR002121, SM00341): HRDC domain Laminin_II (PF06009, IPR010307): Laminin Domain II RQC (PF09382, IPR018982, SM00956): RQC domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain HTH_40 (PF14493, IPR029491): Helix-turn-helix domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding |
331 |
XAF1 | suppressor | 4 | 0.667 | 0.361 | Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain PL48 (PF15903, IPR031780): Filopodia upregulated, FAM65 |
332 |
XPO1 | interactor | 64 | 0.126 | 1053.091 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
333 |
XRCC6 | oncoprotein | 35 | 0.276 | 198.891 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
334 |
YWHAB | interactor | 19 | 0.251 | 73.624 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor |
335 |
YWHAE | oncoprotein | 19 | 0.263 | 64.314 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
336 |
YY1 | protein found in more fusions | 29 | 0.360 | 66.916 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
337 |
ZBTB2 | interactor | 7 | 0.667 | 2.056 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
338 |
ZBTB9 | interactor | 7 | 0.381 | 7.213 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
339 |
ZCCHC12 | interactor | 3 | 1.000 | 0 | PNMA (PF14893, IPR026523): PNMA zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger |
340 |
ZEB1 | interactor | 9 | 0.528 | 2.995 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
341 |
ZNF598 | interactor | 4 | 0.500 | 2.000 | Arc_trans_TRASH (PF08394, IPR013603): Archaeal TRASH domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger |
342 |
ZNF639 | interactor | 1 | 0 | 0 | CarbpepA_inh (PF02977, IPR004231): Carboxypeptidase A inhibitor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |