Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	342
The number (and %) of the onco-proteins	134 (39.18 %)
The number (and %) of the tumor suppressors	77 (22.51 %)
Total number of binary PPIs (saturation %)	3450 (5.92 %)
The number (and %) of affected PPIs	341 (9.88 %)
The number of possible different fusions	75
PPI diameter	2
PPI radius	1
The average degree of PPI	19.281
Assortativity coefficient	-0.2336
The network average Clustering coefficient	0.454
The number (and %) of a zero Clustering coefficients	10 (2.92 %)
The number (and %) of a zero Betweenness Centrality	32 (9.36 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: CREBBP,EIF4E2	All fusions : DA778521;
Proteins found in more fusions	CTBP1 (see 2 fusions); AES (see 3 fusions); VDR (see 2 fusions); SMAD4 (see 2 fusions); RPS6KA2 (see 1 fusions); TCF12 (see 2 fusions); HSF1 (see 3 fusions); BCL6 (see 2 fusions); EBF1 (see 1 fusions); EWSR1 (see 2 fusions); APC (see 1 fusions); AMOTL2 (see 1 fusions); MYBL2 (see 4 fusions); HMGB1/HMGB2 (see 1 fusions); IKBKB (see 2 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); MAP3K5 (see 1 fusions); DDX5 (see 1 fusions); MSH2 (see 1 fusions); STAT1 (see 1 fusions); GRIP1 (see 2 fusions); MSX1 (see 1 fusions); ARIH1 (see 4 fusions); TRAF6 (see 1 fusions); APP (see 4 fusions); MAGED1 (see 1 fusions); MED21 (see 1 fusions); HUWE1 (see 2 fusions); NCOA1 (see 2 fusions); YY1 (see 2 fusions); STAT3 (see 2 fusions); ATF2/DDIT3 (see 1 fusions); KMT2A (see 16 fusions); TCF3 (see 4 fusions); MYOD1 (see 1 fusions); POLR2A (see 2 fusions); CSNK2A1 (see 1 fusions); NLK (see 4 fusions); DDX17 (see 3 fusions); EPAS1 (see 1 fusions); PML (see 4 fusions); PSMC5 (see 2 fusions); MAPK1 (see 1 fusions); HIPK2 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); SMARCB1 (see 12 fusions); MYC (see 1 fusions); SREBF2 (see 2 fusions); PSME3 (see 2 fusions); RUNX1 (see 1 fusions); KRT19 (see 1 fusions); CDH1 (see 3 fusions); KAT2B (see 1 fusions); RARA (see 4 fusions); TMCC2 (see 3 fusions); HTT (see 1 fusions); PARP1 (see 1 fusions); TP53 (see 3 fusions); RARA/PML (see 21 fusions); FOXO1 (see 1 fusions); LYN (see 2 fusions); TRIM28 (see 1 fusions); NR3C1 (see 8 fusions); TRIM27/MDM2 (see 1 fusions); NCOA6 (see 1 fusions); CREB1 (see 2 fusions); SP1 (see 1 fusions); KHDRBS1 (see 1 fusions); PRLR (see 1 fusions); KAT5 (see 3 fusions); FOS (see 4 fusions); FGFR1 (see 2 fusions); SMAD3 (see 3 fusions);

List of the fusions

PPI for parental proteins: CREBBP,EIF4E2

All fusions

: DA778521;

Proteins found in more fusions

CTBP1 (see 2 fusions); AES (see 3 fusions); VDR (see 2 fusions); SMAD4 (see 2 fusions); RPS6KA2 (see 1 fusions); TCF12 (see 2 fusions); HSF1 (see 3 fusions); BCL6 (see 2 fusions); EBF1 (see 1 fusions); EWSR1 (see 2 fusions); APC (see 1 fusions); AMOTL2 (see 1 fusions); MYBL2 (see 4 fusions); HMGB1/HMGB2 (see 1 fusions); IKBKB (see 2 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); MAP3K5 (see 1 fusions); DDX5 (see 1 fusions); MSH2 (see 1 fusions); STAT1 (see 1 fusions); GRIP1 (see 2 fusions); MSX1 (see 1 fusions); ARIH1 (see 4 fusions); TRAF6 (see 1 fusions); APP (see 4 fusions); MAGED1 (see 1 fusions); MED21 (see 1 fusions); HUWE1 (see 2 fusions); NCOA1 (see 2 fusions); YY1 (see 2 fusions); STAT3 (see 2 fusions); ATF2/DDIT3 (see 1 fusions); KMT2A (see 16 fusions); TCF3 (see 4 fusions); MYOD1 (see 1 fusions); POLR2A (see 2 fusions); CSNK2A1 (see 1 fusions); NLK (see 4 fusions); DDX17 (see 3 fusions); EPAS1 (see 1 fusions); PML (see 4 fusions); PSMC5 (see 2 fusions); MAPK1 (see 1 fusions); HIPK2 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); SMARCB1 (see 12 fusions); MYC (see 1 fusions); SREBF2 (see 2 fusions); PSME3 (see 2 fusions); RUNX1 (see 1 fusions); KRT19 (see 1 fusions); CDH1 (see 3 fusions); KAT2B (see 1 fusions); RARA (see 4 fusions); TMCC2 (see 3 fusions); HTT (see 1 fusions); PARP1 (see 1 fusions); TP53 (see 3 fusions); RARA/PML (see 21 fusions); FOXO1 (see 1 fusions); LYN (see 2 fusions); TRIM28 (see 1 fusions); NR3C1 (see 8 fusions); TRIM27/MDM2 (see 1 fusions); NCOA6 (see 1 fusions); CREB1 (see 2 fusions); SP1 (see 1 fusions); KHDRBS1 (see 1 fusions); PRLR (see 1 fusions); KAT5 (see 3 fusions); FOS (see 4 fusions); FGFR1 (see 2 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	DA778521	chimera	341	0.051	69555.005	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
2	ACTA2	interactor	7	0.571	3.037	Actin (PF00022, IPR004000, SM00268): Actin
3	ADAMTSL4	interactor	3	0.667	0.667	ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1 PLAC (PF08686, IPR010909, SM00022): PLAC (protease and lacunin) domain TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
4	AES	protein found in more fusions	22	0.167	135.243	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
5	AIRE	interactor	18	0.375	26.997	PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain
6	AKT1	oncoprotein	42	0.255	240.891	PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
7	AMOTL2	protein found in more fusions	13	0.227	40.467	HOOK (PF05622, IPR008636): HOOK protein SlyX (PF04102, IPR007236): SlyX Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
8	ANAPC2	interactor	12	0.652	8.144	ANAPC2 (PF08672, IPR014786, SM01013): Anaphase promoting complex (APC) subunit 2 Cullin (PF00888, IPR001373, SM00182): Cullin family
9	ANAPC5	interactor	12	0.697	6.419	TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
10	ANAPC7	interactor	12	0.764	3.452	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
11	APC	suppressor	14	0.282	31.798	APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
12	APP	protein found in more fusions	56	0.115	842.275	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
13	AR	oncoprotein	53	0.293	305.622	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
14	ARIH1	protein found in more fusions	5	0.500	0.889	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain Med14 (PF08638, IPR013947): Mediator complex subunit MED14 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
15	ARNTL	suppressor	10	0.578	8.813	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain
16	ATF1	oncoprotein	7	0.619	2.341	bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function
17	ATF2	oncoprotein	30	0.340	88.547	bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
18	ATF3	suppressor	25	0.431	39.408	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
19	ATF4	oncoprotein	19	0.444	37.973	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
20	ATG3	interactor	3	1.000	0	Autophagy_C (PF10381, IPR019461): Autophagocytosis associated protein C-terminal Autophagy_N (PF03986, IPR007134): Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C (PF03987, IPR007135): Autophagocytosis associated protein, active-site domain
21	ATXN3	interactor	21	0.247	70.067	Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
22	BCL6	oncoprotein	24	0.304	90.539	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
23	BMI1	oncoprotein	23	0.333	57.822	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
24	BRCA1	suppressor	59	0.285	394.762	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
25	BRMS1	suppressor	14	0.513	9.674	Dynactin_p62 (PF05502, IPR008603): Dynactin p62 family Sds3 (PF08598, IPR013907): Sds3-like
26	C3orf62	interactor	3	0.667	0.061	DUF4712 (PF15830, IPR031670): Domain of unknown function (DUF4712)
27	CARD9	interactor	11	0.311	22.567	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper IncA (PF04156, IPR007285): IncA protein NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
28	CARM1	oncoprotein	26	0.366	56.299	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
29	CCNA2	oncoprotein	22	0.410	65.052	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
30	CCNC	suppressor	9	0.500	15.300	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
31	CCND3	oncoprotein	9	0.417	6.223	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
32	CCNE1	oncoprotein	16	0.383	27.681	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
33	CDC16	interactor	13	0.603	13.735	Dynein_light (PF01221, IPR001372): Dynein light chain type 1 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
34	CDC20	oncoprotein	28	0.305	134.666	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
35	CDC27	oncoprotein	22	0.362	58.547	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat
36	CDH1	suppressor	12	0.491	10.316	Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
37	CDH2	interactor	3	1.000	0	Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain Cadherin_3 (PF16184): Cadherin-like
38	CDK2	suppressor	51	0.233	434.316	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
39	CDK8	interactor	26	0.417	61.042	Pkinase (PF00069, IPR000719): Protein kinase domain
40	CDKN1A	suppressor	44	0.244	335.497	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
41	CDR2	interactor	6	0.500	2.533	DivIC (PF04977, IPR007060): Septum formation initiator SlyX (PF04102, IPR007236): SlyX Striatin (PF08232, IPR013258): Striatin family BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
42	CEBPB	oncoprotein	43	0.347	147.284	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
43	CEBPD	suppressor	14	0.484	19.552	bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
44	CENPJ	interactor	5	0.500	2.733	DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus TSC22 (PF01166, IPR000580): TSC-22/dip/bun family AAA_23 (PF13476): AAA domain DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
45	CHUK	suppressor	28	0.422	63.270	Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
46	CITED1	interactor	6	0.667	2.650	CITED (PF04487, IPR007576): CITED
47	CITED2	suppressor	8	0.536	4.448	CITED (PF04487, IPR007576): CITED
48	CLOCK	interactor	6	1.000	0	DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PAS (PF00989, IPR013767, SM00091): PAS fold RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 PAS_11 (PF14598): PAS domain FlgT_N (PF16548, IPR032370): Flagellar assembly protein T, N-terminal domain
49	COPS2	suppressor	15	0.419	20.817	YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
50	CPSF6	interactor	9	0.444	6.338	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1
51	CREB1	oncoprotein	38	0.266	227.481	bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function
52	CREM	suppressor	7	0.571	2.585	bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987)
53	CRTC1	oncoprotein	6	0.533	3.436	TORC_N (PF12884, IPR024783): Transducer of regulated CREB activity, N terminus TORC_M (PF12885, IPR024784): Transducer of regulated CREB activity middle domain TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus
54	CSNK2A1	oncoprotein	45	0.204	381.953	Pkinase (PF00069, IPR000719): Protein kinase domain
55	CSNK2A2	interactor	14	0.308	29.516	Pkinase (PF00069, IPR000719): Protein kinase domain
56	CTBP1	protein found in more fusions	32	0.318	109.245	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
57	CTNNB1	oncoprotein	58	0.199	616.844	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
58	CUX1	suppressor	4	0.500	2.167	Baculo_p24 (PF05073, IPR007765): Baculovirus P24 capsid protein CUT (PF02376, IPR003350, SM01109): CUT domain DegS (PF05384, IPR008595): Sensor protein DegS DivIC (PF04977, IPR007060): Septum formation initiator DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Swi5 (PF07061, IPR010760): Swi5 TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein ApoO (PF09769, IPR019166): Apolipoprotein O Homeobox (PF00046, IPR001356, SM00389): Homeobox domain RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
59	DAXX	oncoprotein	37	0.267	175.016	Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
60	DDIT3	oncoprotein	17	0.467	30.598	IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
61	DDX17	protein found in more fusions	24	0.411	40.162	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
62	DDX5	oncoprotein	30	0.365	88.825	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
63	DEK	oncoprotein	15	0.476	12.434	DEK_C (PF08766, IPR014876): DEK C terminal domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family SAP (PF02037, IPR003034, SM00513): SAP domain Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
64	DYRK1A	oncoprotein	17	0.325	32.771	DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X
65	DYRK1B	oncoprotein	9	0.429	8.032	Pkinase (PF00069, IPR000719): Protein kinase domain
66	E2F1	suppressor	34	0.319	144.636	Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
67	E2F3	suppressor	10	0.311	11.419	E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
68	EBF1	oncoprotein	4	0.667	0.667	TIG (PF01833, IPR002909): IPT/TIG domain COE1_DBD (PF16422, IPR032200): Transcription factor COE1 DNA-binding domain COE1_HLH (PF16423, IPR032201): Transcription factor COE1 helix-loop-helix domain
69	EGR1	suppressor	11	0.564	6.261	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432) DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
70	EID3	interactor	4	0.667	0.667	Nse4_C (PF08743, IPR014854): Nse4 C-terminal Nse4-Nse3_bdg (PF15412, IPR029225): Binding domain of Nse4/EID3 to Nse3-MAGE
71	EIF3F	suppressor	5	0.700	0.804	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
72	ELAVL1	oncoprotein	67	0.119	1071.767	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
73	ELK1	oncoprotein	14	0.333	20.528	Ets (PF00178, IPR000418, SM00413): Ets-domain Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain
74	EP300	oncoprotein	176	0.097	8628.522	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
75	EPAS1	suppressor	20	0.380	38.071	Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
76	ESR1	suppressor	85	0.208	1195.338	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
77	ESR2	suppressor	25	0.333	66.870	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
78	ETS1	oncoprotein	25	0.427	55.131	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
79	ETS2	suppressor	12	0.697	3.172	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
80	EWSR1	oncoprotein	42	0.195	333.379	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
81	FAM58A	interactor	2	1.000	0	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
82	FBXO25	suppressor	10	0.222	21.061	Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
83	FBXW11	interactor	22	0.205	107.448	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
84	FERMT3	interactor	3	0.667	0.500	FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
85	FGFR1	oncoprotein	8	0.429	6.327	I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
86	FHL1	suppressor	11	0.709	3.214	LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
87	FHL2	oncoprotein	28	0.356	73.721	LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain
88	FOS	oncoprotein	38	0.288	189.610	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
89	FOSB	oncoprotein	4	1.000	0	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Motilin_ghrelin (PF04644, IPR006738): Motilin/ghrelin
90	FOSL1	oncoprotein	11	0.673	4.208	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
91	FOXM1	oncoprotein	9	0.444	6.569	EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
92	FOXO1	suppressor	24	0.395	57.765	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
93	FOXO3	suppressor	22	0.446	37.417	Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
94	FOXO4	suppressor	13	0.513	11.315	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
95	GATA1	oncoprotein	10	0.578	9.272	GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain
96	GCM1	interactor	4	0.667	0.126	DUF1272 (PF06906, IPR010696): Protein of unknown function (DUF1272) GCM (PF03615, IPR003902): GCM motif protein
97	GIGYF2	interactor	13	0.308	31.749	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
98	GLI3	oncoprotein	4	0.667	0.650	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
99	GRIP1	protein found in more fusions	16	0.571	9.837	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
100	GTF2B	interactor	18	0.392	36.892	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
101	HBP1	suppressor	8	0.607	2.635	AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
102	HCK	oncoprotein	9	0.500	8.682	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
103	HDAC1	suppressor	99	0.173	1889.731	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
104	HDAC2	suppressor	63	0.221	533.913	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
105	HDAC3	suppressor	53	0.244	334.686	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
106	HES6	interactor	1	0	0	Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
107	HIF1A	suppressor	35	0.445	84.500	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
108	HIPK2	suppressor	23	0.307	91.547	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
109	HIST1H2BB	interactor	11	0.491	8.104	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
110	HIST1H3A	interactor	35	0.266	172.553	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
111	HIST1H4A	interactor	28	0.315	84.927	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
112	HIST2H2BE	interactor	18	0.366	36.188	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
113	HIST3H3	interactor	28	0.288	113.740	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
114	HIST4H4	interactor	13	0.474	9.028	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
115	HMGA1	oncoprotein	23	0.391	44.607	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
116	HMGB1	oncoprotein	20	0.284	69.862	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
117	HMGB2	protein found in more fusions	8	0.500	2.920	HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
118	HNF1A	oncoprotein	14	0.346	24.410	HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
119	HNF4A	suppressor	29	0.344	73.113	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
120	HOMEZ	interactor	4	0.500	2.333	Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Homez (PF11569, IPR024578): Homeodomain leucine-zipper encoding, Homez WRNPLPNID (PF15017): Putative WW-binding domain and destruction box PRIMA1 (PF16101): Proline-rich membrane anchor 1
121	HOXA10	interactor	3	0.667	0.400	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266)
122	HOXA9	oncoprotein	5	0.500	2.377	Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
123	HOXB2	interactor	1	0	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
124	HOXB3	interactor	2	1.000	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4074 (PF13293, IPR025281): Domain of unknown function (DUF4074) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
125	HOXB4	interactor	1	0	0	DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
126	HOXB6	interactor	1	0	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
127	HOXB7	interactor	5	0.500	1.971	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
128	HOXB9	interactor	4	0.500	1.567	Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
129	HOXD10	interactor	3	0.667	0.154	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
130	HOXD12	interactor	3	0.667	0.500	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
131	HOXD13	oncoprotein	5	0.600	1.011	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal
132	HOXD4	interactor	5	0.600	1.519	SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
133	HSF1	protein found in more fusions	16	0.381	16.664	DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
134	HTT	protein found in more fusions	20	0.368	32.841	HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
135	HUWE1	oncoprotein	39	0.174	303.008	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
136	IFNAR2	interactor	5	1.000	0	Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor
137	IKBKB	protein found in more fusions	18	0.426	23.729	FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
138	IKBKG	interactor	18	0.331	34.788	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
139	ING1	suppressor	19	0.433	27.913	PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
140	IRF1	suppressor	10	0.533	7.932	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
141	IRF3	suppressor	15	0.440	24.556	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
142	IRF5	suppressor	11	0.511	6.096	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
143	IRF7	interactor	10	0.611	3.694	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
144	IRF9	interactor	7	0.571	4.629	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
145	JUN	oncoprotein	72	0.233	877.085	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
146	JUNB	oncoprotein	16	0.400	26.632	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
147	KAT2B	protein found in more fusions	75	0.154	1175.789	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
148	KAT5	suppressor	42	0.270	246.011	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
149	KAT6A	oncoprotein	15	0.419	14.940	BUD22 (PF09073, IPR015158): BUD22 MOZ_SAS (PF01853, IPR002717): MOZ/SAS family PHD (PF00628, IPR019787, SM00249): PHD-finger Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) zf-met (PF12874): Zinc-finger of C2H2 type
150	KDM3B	suppressor	5	0.500	1.606	JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
151	KHDRBS1	protein found in more fusions	17	0.300	42.776	KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
152	KLF1	interactor	7	0.571	2.520	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain EKLF_TAD1 (PF16832, IPR031786): Erythroid krueppel-like transcription factor, transactivation 1 EKLF_TAD2 (PF16833, IPR031784): Erythroid krueppel-like transcription factor, transactivation 2
153	KLF13	interactor	5	0.800	0.650	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
154	KLF2	interactor	5	0.500	1.118	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
155	KLF4	suppressor	13	0.577	7.686	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
156	KLF5	suppressor	24	0.500	25.582	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
157	KLF8	interactor	7	0.524	1.467	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
158	KMT2A	oncoprotein	24	0.372	50.763	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
159	KPNA2	interactor	23	0.225	117.136	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
160	KPNA6	interactor	8	0.250	11.193	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
161	KRT13	interactor	5	0.400	4.167	Filament (PF00038, IPR001664): Intermediate filament protein FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus Keratin_2_head (PF16208, IPR032444): Keratin type II head
162	KRT19	suppressor	8	0.381	8.567	Filament (PF00038, IPR001664): Intermediate filament protein
163	KRT31	interactor	9	0.306	17.983	Filament (PF00038, IPR001664): Intermediate filament protein
164	KRTAP10-5	interactor	7	0.400	8.000	Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
165	KRTAP10-8	interactor	5	0.667	1.667	Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein PMG (PF05287, IPR007951): PMG protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
166	LDLR	interactor	1	0	0	EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B hEGF (PF12661, IPR013032): Human growth factor-like EGF FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
167	LIG4	interactor	3	0.667	0.333	APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
168	LYN	oncoprotein	14	0.397	18.185	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
169	LZTS2	suppressor	11	0.200	31.706	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127) Fez1 (PF06818): Fez1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
170	MAF	oncoprotein	13	0.424	17.933	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Maf_N (PF08383, IPR013592): Maf N-terminal region NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen TraT (PF05818, IPR008874): Enterobacterial TraT complement resistance protein Metal_resist (PF13801, IPR025961): Heavy-metal resistance
171	MAFK	oncoprotein	12	0.561	13.285	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
172	MAGED1	protein found in more fusions	9	0.393	7.076	MAGE (PF01454, IPR002190): MAGE family
173	MAML1	interactor	8	0.393	6.692	MamL-1 (PF09596, IPR019082): MamL-1 domain Kri1 (PF05178, IPR018034): KRI1-like family PRIMA1 (PF16101): Proline-rich membrane anchor 1
174	MAML2	oncoprotein	3	1.000	0	Senescence_reg (PF04520, IPR007608): Senescence regulator BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal MamL-1 (PF09596, IPR019082): MamL-1 domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
175	MAP3K5	oncoprotein	11	0.444	7.792	Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
176	MAPK1	oncoprotein	42	0.270	267.773	Pkinase (PF00069, IPR000719): Protein kinase domain
177	MAPK10	suppressor	10	0.556	3.019	Pkinase (PF00069, IPR000719): Protein kinase domain
178	MAPK3	oncoprotein	27	0.240	140.640	Pkinase (PF00069, IPR000719): Protein kinase domain
179	MAPRE3	interactor	2	1.000	0	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif
180	MDC1	suppressor	18	0.399	43.037	FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
181	MDFI	interactor	11	0.267	24.034	MDFI (PF15316, IPR026134): MyoD family inhibitor
182	MDM2	oncoprotein	65	0.205	667.820	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
183	MECOM	oncoprotein	11	0.582	4.050	SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
184	MED21	protein found in more fusions	21	0.374	45.820	Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
185	MED23	interactor	33	0.267	170.222	Med23 (PF11573, IPR021629): Mediator complex subunit 23
186	MED25	interactor	11	0.467	7.494	Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1 Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A
187	MEIS1	oncoprotein	6	0.467	5.200	Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Meis_PKNOX_N (PF16493, IPR032453): N-terminal of Homeobox Meis and PKNOX1
188	MGMT	interactor	13	0.487	12.253	DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
189	MIER1	oncoprotein	6	0.600	1.047	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain ELM2 (PF01448, IPR000949): ELM2 domain HpaP (PF09483, IPR013390): Type III secretion protein (HpaP) SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
190	MIPOL1	interactor	2	0	0	Bac_globin (PF01152, IPR001486): Bacterial-like globin CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003) ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Rho_Binding (PF08912, IPR015008): Rho Binding IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D
191	MKNK1	interactor	8	0.321	6.809	Pkinase (PF00069, IPR000719): Protein kinase domain
192	MSH2	suppressor	17	0.483	20.945	MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain
193	MSH6	oncoprotein	11	0.636	8.585	MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II PWWP (PF00855, IPR000313, SM00293): PWWP domain MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70
194	MSX1	protein found in more fusions	4	1.000	0	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
195	MTDH	interactor	4	0.833	0.083	NST1 (PF13945, IPR025279): Salt tolerance down-regulator NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain LYRIC (PF15686, IPR031402): Lysine-rich CEACAM1 co-isolated protein family
196	MTF1	interactor	2	1.000	0	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Marek_A (PF02124, IPR001038): Marek's disease glycoprotein A zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
197	MUS81	suppressor	5	0.400	5.000	ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MutL (PF13941, IPR006230): MutL protein HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
198	MYB	oncoprotein	19	0.327	43.231	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
199	MYBL1	oncoprotein	3	1.000	0	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
200	MYBL2	oncoprotein	14	0.359	26.227	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
201	MYC	oncoprotein	65	0.259	566.087	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
202	MYH9	suppressor	16	0.317	40.554	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
203	MYOD1	oncoprotein	26	0.347	65.084	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5
204	MYOG	interactor	12	0.288	28.440	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
205	N4BP2	interactor	4	1.000	0	CUE (PF02845, IPR003892, SM00546): CUE domain DUF1771 (PF08590, IPR013899, SM01162): Domain of unknown function (DUF1771) RyR (PF02026, IPR003032): RyR domain Smr (PF01713, IPR002625, SM00463): Smr domain AAA_22 (PF13401, IPR003593): AAA domain AAA_33 (PF13671): AAA domain
206	NCOA1	oncoprotein	39	0.353	145.823	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
207	NCOA2	oncoprotein	25	0.393	58.309	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
208	NCOA3	oncoprotein	41	0.306	205.038	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
209	NCOA6	oncoprotein	33	0.373	86.823	DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator
210	NCOR1	oncoprotein	48	0.301	246.559	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region
211	NCOR2	oncoprotein	37	0.414	89.093	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
212	NEUROG1	interactor	4	0.833	0.500	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Transformer (PF06495, IPR010519): Fruit fly transformer protein
213	NFATC2	suppressor	5	1.000	0	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
214	NFATC4	interactor	2	1.000	0	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
215	NFE2	interactor	5	0.833	0.222	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Peptidase_Mx (PF15887, IPR031321): Putative zinc-binding metallo-peptidase
216	NFE2L2	oncoprotein	19	0.409	38.269	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
217	NFYB	interactor	13	0.654	7.202	CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
218	NKX2-1	oncoprotein	7	0.619	2.098	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF4719 (PF15843, IPR031696): Domain of unknown function (DUF4719)
219	NLK	protein found in more fusions	16	0.333	38.669	Pkinase (PF00069, IPR000719): Protein kinase domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
220	NOTCH2NL	interactor	8	0.321	14.233	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
221	NPAS2	suppressor	7	0.905	0.800	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold DehI (PF10778, IPR019714): Halocarboxylic acid dehydrogenase DehI PAS_11 (PF14598): PAS domain
222	NPAT	interactor	5	0.500	2.786	Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 NPAT_C (PF15712, IPR031442): NPAT C terminus
223	NR3C1	protein found in more fusions	46	0.282	305.138	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
224	NR3C2	oncoprotein	7	0.619	1.436	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
225	NR5A1	interactor	9	0.444	5.308	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PRIMA1 (PF16101): Proline-rich membrane anchor 1
226	NUP98	suppressor	8	0.536	4.296	Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head
227	ONECUT1	suppressor	3	0.667	0.154	CUT (PF02376, IPR003350, SM01109): CUT domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
228	PAPOLA	interactor	8	0.321	6.227	PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain Macoilin (PF09726, IPR019130): Transmembrane protein
229	PARP1	suppressor	48	0.278	310.981	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
230	PBX1	oncoprotein	13	0.295	36.610	PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
231	PCNA	oncoprotein	36	0.261	204.405	PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
232	PELP1	interactor	14	0.429	16.186	RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis NUC202 (PF08166, IPR012980): NUC202 domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
233	PHOX2A	suppressor	4	1.000	0	Phage_Mu_Gam (PF07352, IPR009951): Bacteriophage Mu Gam like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
234	PHOX2B	oncoprotein	1	0	0	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TraC (PF07820, IPR012930): TraC-like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
235	PIAS3	oncoprotein	14	0.451	15.697	SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
236	PLAGL1	suppressor	10	0.778	1.083	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
237	PML	suppressor	53	0.261	360.782	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
238	POLR2A	protein found in more fusions	37	0.281	159.010	RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
239	POT1	interactor	8	0.381	7.427	POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
240	POU1F1	interactor	7	0.714	1.372	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2
241	POU2F3	suppressor	2	1.000	0	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
242	PPARG	suppressor	42	0.339	170.991	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
243	PPARGC1A	interactor	17	0.522	13.614	Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1
244	PPP1R13L	oncoprotein	7	0.619	3.516	Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SH3_9 (PF14604, IPR001452): Variant SH3 domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
245	PRDM14	interactor	1	0	0	Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
246	PRLR	oncoprotein	3	1.000	0	EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
247	PSMC5	protein found in more fusions	27	0.274	97.337	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain
248	PSME3	protein found in more fusions	15	0.363	28.444	PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
249	PTMA	oncoprotein	12	0.424	10.054	Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
250	PTMS	interactor	7	0.429	3.616	Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
251	PTOV1	interactor	1	0	0	Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2
252	PTTG1	oncoprotein	12	0.345	20.147	Securin (PF04856, IPR006940): Securin sister-chromatid separation inhibitor
253	PYGO2	interactor	5	0.667	0.348	PHD (PF00628, IPR019787, SM00249): PHD-finger
254	RAD23A	oncoprotein	13	0.470	13.383	UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
255	RARA	oncoprotein	36	0.271	169.997	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
256	RBBP4	oncoprotein	30	0.375	88.762	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
257	RBBP7	suppressor	20	0.432	48.035	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
258	REL	oncoprotein	14	0.407	20.714	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
259	RELA	oncoprotein	69	0.218	810.539	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
260	RPA2	oncoprotein	23	0.277	90.719	RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
261	RPS6KA1	oncoprotein	9	0.444	10.013	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
262	RPS6KA2	suppressor	7	0.800	1.119	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
263	RPS6KA3	interactor	7	0.524	6.061	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
264	RPS6KA5	interactor	14	0.363	27.153	Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
265	RUNX1	suppressor	31	0.372	81.481	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
266	RUNX2	suppressor	17	0.596	8.959	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
267	RUVBL1	oncoprotein	19	0.373	31.629	TIP49 (PF06068, IPR010339): TIP49 C-terminus
268	SERTAD1	interactor	6	0.533	2.710	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal SERTA (PF06031, IPR009263): SERTA motif
269	SETD1A	interactor	6	0.733	0.644	E7 (PF00527, IPR000148): E7 protein, Early protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET (PF00856, IPR001214, SM00317): SET domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632) DUF4667 (PF15700, IPR031426): Domain of unknown function (DUF4667) PRIMA1 (PF16101): Proline-rich membrane anchor 1
270	SH3GL1	oncoprotein	5	0.667	0.722	BAR (PF03114, IPR004148, SM00721): BAR domain PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
271	SMAD1	interactor	27	0.317	105.443	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
272	SMAD2	suppressor	47	0.274	292.466	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
273	SMAD3	oncoprotein	71	0.240	694.212	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
274	SMAD4	suppressor	41	0.291	208.185	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
275	SMARCA2	suppressor	32	0.401	83.449	DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
276	SMARCA4	suppressor	62	0.233	558.419	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
277	SMARCB1	suppressor	32	0.316	121.128	SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
278	SNAI1	oncoprotein	15	0.438	31.205	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
279	SND1	interactor	11	0.400	8.719	TUDOR (PF00567, IPR002999, SM00333): Tudor domain SNase (PF00565, IPR016071, SM00318): Staphylococcal nuclease homologue
280	SNIP1	interactor	8	0.643	5.890	FHA (PF00498, IPR000253, SM00240): FHA domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 FAM176 (PF14851): FAM176 family
281	SP1	protein found in more fusions	65	0.249	651.444	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
282	SP3	interactor	12	0.773	2.106	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
283	SPAG5	interactor	3	0.667	0.667	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF1307 (PF06998, IPR009736): Protein of unknown function (DUF1307) DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
284	SRC	oncoprotein	28	0.291	101.983	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
285	SRCAP	interactor	7	0.667	1.292	AT_hook (PF02178, IPR017956, SM00384): AT hook motif HSA (PF07529, IPR014012, SM00573): HSA RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
286	SREBF1	interactor	17	0.417	26.279	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
287	SREBF2	protein found in more fusions	16	0.438	26.839	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
288	SRF	interactor	22	0.324	46.079	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
289	SS18L1	oncoprotein	10	0.611	2.613	DUF1313 (PF07011, IPR009741): Protein of unknown function (DUF1313) SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
290	STAT1	suppressor	27	0.378	77.455	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
291	STAT2	oncoprotein	10	0.444	9.962	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal
292	STAT3	suppressor	43	0.286	237.848	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
293	STAT6	oncoprotein	13	0.462	16.415	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT6_C (PF14596, IPR028187): STAT6 C-terminal
294	TACC2	interactor	4	0.833	0.100	TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
295	TADA2A	interactor	20	0.337	44.769	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
296	TAF6L	interactor	5	0.600	2.686	TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
297	TBP	interactor	41	0.306	208.006	TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
298	TBX21	oncoprotein	3	1.000	0	T-box (PF00907, IPR001699, SM00425): T-box T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated
299	TCF12	oncoprotein	13	0.561	8.248	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
300	TCF3	suppressor	19	0.399	27.178	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
301	TCF4	suppressor	17	0.353	33.025	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
302	TDG	interactor	17	0.441	16.466	Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
303	TFAP2B	interactor	5	0.500	2.317	TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2
304	TFDP1	oncoprotein	9	0.528	6.281	DP (PF08781, IPR014889, SM01138): Transcription factor DP E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
305	TGS1	interactor	5	0.700	0.418	DinI (PF06183, IPR010391): DinI-like family DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Methyltransf_15 (PF09445, IPR019012): RNA cap guanine-N2 methyltransferase Presenilin (PF01080, IPR001108): Presenilin
306	TLE3	interactor	6	0.400	2.337	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
307	TLR2	interactor	3	1.000	0	LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
308	TMCC2	protein found in more fusions	7	0.467	5.067	Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
309	TP53	suppressor	111	0.160	2462.530	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
310	TP73	suppressor	26	0.403	62.846	P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
311	TRAF6	protein found in more fusions	26	0.237	112.283	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
312	TRERF1	interactor	5	0.600	0.704	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal ELM2 (PF01448, IPR000949): ELM2 domain Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2681 (PF10883, IPR020274): Protein of unknown function (DUF2681) MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger PRIMA1 (PF16101): Proline-rich membrane anchor 1
313	TRIM27	oncoprotein	19	0.327	50.018	IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
314	TRIM28	protein found in more fusions	36	0.255	182.632	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
315	TRIM54	interactor	11	0.289	19.223	DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) zf-HIT (PF04438, IPR007529): HIT zinc finger zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
316	TRIP4	interactor	14	0.538	10.334	ASCH (PF04266, IPR007374, SM01022): ASCH domain UxaC (PF02614, IPR003766): Glucuronate isomerase zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
317	TUBGCP3	interactor	8	0.464	4.895	Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
318	TXNDC11	interactor	3	0.667	0.500	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain
319	UBE2D1	interactor	18	0.338	35.332	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
320	UBE2I	interactor	74	0.183	982.743	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
321	UBE2L3	interactor	17	0.317	35.809	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
322	UBE2S	interactor	11	0.578	14.067	ALF (PF03752, IPR005506): Short repeats of unknown function UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
323	UBXN11	interactor	3	0.667	0.667	DivIC (PF04977, IPR007060): Septum formation initiator SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) TRPM_tetra (PF16519, IPR032415): Tetramerisation domain of TRPM
324	USHBP1	interactor	7	0.400	7.167	DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper SlyX (PF04102, IPR007236): SlyX MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome YlqD (PF11068, IPR021297): YlqD protein DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) CAGE1 (PF15066, IPR029381): Cancer-associated gene protein 1 family TEX13 (PF15186, IPR028193): Testis-expressed sequence 13 protein family
325	USP4	oncoprotein	13	0.409	16.177	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
326	USP54	interactor	3	1.000	0	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
327	VDR	suppressor	36	0.329	135.412	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
328	WDR5	interactor	27	0.274	108.851	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
329	WDR83	interactor	6	0.400	6.733	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
330	WRN	oncoprotein	12	0.473	17.002	DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease DEAD (PF00270, IPR011545): DEAD/DEAH box helicase HRDC (PF00570, IPR002121, SM00341): HRDC domain Laminin_II (PF06009, IPR010307): Laminin Domain II RQC (PF09382, IPR018982, SM00956): RQC domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain HTH_40 (PF14493, IPR029491): Helix-turn-helix domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
331	XAF1	suppressor	4	0.667	0.361	Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain PL48 (PF15903, IPR031780): Filopodia upregulated, FAM65
332	XPO1	interactor	64	0.126	1053.091	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
333	XRCC6	oncoprotein	35	0.276	198.891	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain
334	YWHAB	interactor	19	0.251	73.624	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor
335	YWHAE	oncoprotein	19	0.263	64.314	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
336	YY1	protein found in more fusions	29	0.360	66.916	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
337	ZBTB2	interactor	7	0.667	2.056	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
338	ZBTB9	interactor	7	0.381	7.213	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type PRIMA1 (PF16101): Proline-rich membrane anchor 1
339	ZCCHC12	interactor	3	1.000	0	PNMA (PF14893, IPR026523): PNMA zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
340	ZEB1	interactor	9	0.528	2.995	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
341	ZNF598	interactor	4	0.500	2.000	Arc_trans_TRASH (PF08394, IPR013603): Archaeal TRASH domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger
342	ZNF639	interactor	1	0	0	CarbpepA_inh (PF02977, IPR004231): Carboxypeptidase A inhibitor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain

B a c k t o T o p ⇑

List of missing interactors

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	CREBBP	parental protein	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
2	DIS3L	interactor	RNB (PF00773, SM00955): RNB domain Rrp44_CSD1 (PF17216): Rrp44-like cold shock domain Rrp44_S1 (PF17215): S1 domain
3	EID1	interactor	NA
4	EIF4E2	parental protein	IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
5	EIF4EBP3	interactor	eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
6	EIF4ENIF1	interactor	EIF4E-T (PF10477, IPR018862): Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
7	GIGYF1	interactor	GYF (PF02213, IPR003169, SM00444): GYF domain RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component) PRTase_3 (PF15610, IPR028944): PRTase ComF-like VIR_N (PF15912, IPR031801): Virilizer, N-terminal
8	KRT20	interactor	Duffy_binding (PF05424, IPR008602): Duffy binding domain Filament (PF00038, IPR001664): Intermediate filament protein
9	KRT40	interactor	Filament (PF00038, IPR001664): Intermediate filament protein UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184)
10	KRTAP10-9	interactor	Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
11	KRTAP4-12	interactor	Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
12	NECAB2	interactor	ABM (PF03992, IPR007138): Antibiotic biosynthesis monooxygenase EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
13	SPERT	interactor	ZapB (PF06005, IPR009252): Cell division protein ZapB DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Chibby (PF14645, IPR028118): Chibby family JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
14	SPRY2	suppressor	KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9 Sprouty (PF05210, IPR007875): Sprouty protein (Spry)

B a c k t o T o p ⇑

Fusion ID: Protein names:	DA778521
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List of the fusions

List of active interactors

List of missing interactors