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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: DA592957 is the fusion of parental proteins PABPC1, HLA-DQB1 (from a repository: Mon Dec 5 17:06:06 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)226
The number (and %) of the onco-proteins67 (29.65 %)
The number (and %) of the tumor suppressors25 (11.06 %)
Total number of binary PPIs (saturation %)3771 (14.83 %)
The number (and %) of affected PPIs225 (5.97 %)
The number of possible different fusions50
PPI diameter2
PPI radius1
The average degree of PPI32.584
Assortativity coefficient-0.1342
The network average Clustering coefficient0.501
The number (and %) of a zero Clustering coefficients1 (0.44 %)
The number (and %) of a zero Betweenness Centrality8 (3.54 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: HLA-DQB1,PABPC1 All fusions
: DA592957;
Proteins found in more fusions EEF1G (see 1 fusions); U2AF2 (see 2 fusions); RPL37A/PRPF8 (see 1 fusions); CUL1 (see 3 fusions); UBA1 (see 2 fusions); GAN (see 1 fusions); HDAC5 (see 1 fusions); RPA1 (see 1 fusions); RPLP2 (see 1 fusions); PRPF3 (see 1 fusions); SNW1 (see 1 fusions); ZMYND11 (see 1 fusions); CUL4A (see 4 fusions); RPL27/RPS6 (see 1 fusions); SRPK2 (see 1 fusions); HNRNPD (see 1 fusions); SNRNP200 (see 3 fusions); ACAT2 (see 1 fusions); PRPF8 (see 3 fusions); BAG3 (see 4 fusions); ATP5A1 (see 1 fusions); NCL (see 3 fusions); STAU1 (see 2 fusions); EEF1A1 (see 1 fusions); NTRK1/RPL7A (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); SKI (see 1 fusions); SMG6 (see 1 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); FN1/YWHAG (see 1 fusions); TP53 (see 3 fusions); SREK1 (see 4 fusions); G3BP1 (see 1 fusions); YWHAG (see 1 fusions); LUC7L2 (see 2 fusions); PUF60 (see 2 fusions); PDCD6 (see 1 fusions); SERBP1 (see 1 fusions); PCBP2 (see 3 fusions); EIF4A2 (see 2 fusions); SH3KBP1 (see 1 fusions); MCM2 (see 1 fusions); UBR5 (see 4 fusions); RACK1 (see 3 fusions); USP10 (see 1 fusions); FN1/RPL6 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DA592957chimera2250.13719773.139RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
2 ACAT2protein found in more fusions60.7001.221Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
3 AGO1interactor120.50016.789ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
4 AGO2interactor230.40360.972ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
5 AIREinteractor70.6670.971PHD (PF00628, IPR019787, SM00249): PHD-finger
SAND (PF01342, IPR000770, SM00258): SAND domain
HSR (PF03172, IPR004865): HSR domain; Sp100 domain
zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain
6 ALYREFinteractor360.34564.936FYTT (PF07078, IPR009782): Forty-two-three protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
7 ANAPC5interactor40.5001.536TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
8 APBB1interactor90.6071.616PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
9 APEX1interactor100.5782.774Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
10 ARRB2interactor440.413110.631Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
11 ATP5A1protein found in more fusions320.38562.401ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
12 ATP6V1B2interactor100.4225.876ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
13 ATXN2interactor100.5787.308LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Spt20 (PF12090, IPR021950): Spt20 family
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
14 ATXN2Linteractor110.4737.204LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
15 BAG3oncoprotein210.19568.686BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
16 BCAR3oncoprotein100RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
17 BRCA1suppressor260.263104.338BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
18 BRIX1interactor220.8272.220Brix (PF04427, IPR007109, SM00879): Brix domain
19 CAND1interactor950.367564.539Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
20 CCDC8interactor520.391165.472Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
21 CD81interactor410.42666.505Tetraspannin (PF00335, IPR018499): Tetraspanin family
22 CEP250interactor440.469139.275ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
23 CHAF1Ainteractor90.25013.317CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term
CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA
24 CLK2interactor90.5006.533DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-met (PF12874): Zinc-finger of C2H2 type
25 CLK3interactor70.6671.387Pkinase (PF00069, IPR000719): Protein kinase domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
26 CNOT6interactor80.5716.287Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
27 CNOT7interactor140.38532.660CAF1 (PF04857, IPR006941): CAF1 family ribonuclease
28 COPS5protein found in more fusions840.387409.235JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
29 COPS6interactor310.61822.795DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
30 CRY1interactor180.35316.302DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
31 CSF2suppressor51.0000GM_CSF (PF01109, IPR000773, SM00040): Granulocyte-macrophage colony-stimulating factor
32 CSTF2interactor120.31822.976RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
33 CSTF3interactor110.49111.276NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
34 CUL1suppressor860.353546.560Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
35 CUL2suppressor600.446160.251Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
36 CUL3protein found in more fusions1100.2821215.849Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
37 CUL4Aprotein found in more fusions280.61834.156Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
38 CUL4Boncoprotein500.516103.512Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
39 CUL5suppressor590.503113.275Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
40 CUL7protein found in more fusions760.320421.497ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
41 DCUN1D1interactor330.67419.086Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
42 DDX19Ainteractor60.6001.930DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
43 DDX39Ainteractor110.4677.844DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
44 DDX39Binteractor230.31648.611DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
45 DHX15interactor500.318227.851DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
46 DYNLL1interactor110.5337.860Dynein_light (PF01221, IPR001372): Dynein light chain type 1
47 EEF1A1suppressor740.424317.780GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
48 EEF1A2oncoprotein240.46719.572GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
49 EEF1Gprotein found in more fusions300.42940.144EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
50 EEF2interactor470.512129.965EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
51 EIF4A1interactor340.337100.745DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
52 EIF4A2oncoprotein150.38522.611DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
53 EIF4Binteractor230.25572.295RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3774 (PF12609, IPR022251): Wound-induced protein
PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
54 EIF4Eoncoprotein80.6794.198IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
55 EIF4G1oncoprotein250.36762.129DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
56 EIF4G3interactor100.6005.109MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
57 ELAVL1oncoprotein710.217939.354RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
58 ESR1suppressor670.383332.996Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
59 ETF1interactor60.6672.467eRF1_1 (PF03463, IPR005140): eRF1 domain 1
eRF1_2 (PF03464, IPR005141): eRF1 domain 2
eRF1_3 (PF03465, IPR005142): eRF1 domain 3
60 FBXO6interactor400.346104.876FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
61 FBXW11interactor260.34770.560WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
62 FDPSinteractor50.9000.118polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase
63 FN1oncoprotein770.352354.792fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
64 G3BP1protein found in more fusions310.46745.863NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
65 G3BP2interactor200.54217.384NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
66 GANprotein found in more fusions210.58411.397BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
67 GIGYF2interactor170.44123.398DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
GYF (PF02213, IPR003169, SM00444): GYF domain
Macoilin (PF09726, IPR019130): Transmembrane protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
AAA_23 (PF13476): AAA domain
ARGLU (PF15346): Arginine and glutamate-rich 1
PRTase_3 (PF15610, IPR028944): PRTase ComF-like
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
68 GNPDA1interactor21.0000Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
69 GSPT1oncoprotein140.51618.265GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
70 GSPT2interactor60.7331.917GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
71 H2AFXsuppressor230.39133.285Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
72 HAUS1interactor80.4764.681THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
73 HBBinteractor70.4294.579Globin (PF00042, IPR000971): Globin
74 HDAC5protein found in more fusions430.37789.491Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
75 HIST1H3Einteractor280.34791.007Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
76 HNRNPA1interactor890.312875.724RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
77 HNRNPDoncoprotein610.326322.017CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
78 HNRNPKoncoprotein650.353344.378ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
79 HNRNPRinteractor520.447101.608RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
80 HNRNPUinteractor930.395571.493CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
81 HSPA8oncoprotein500.362215.394HSP70 (PF00012, IPR013126): Hsp70 protein
82 ICAM1oncoprotein320.60318.207Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
83 IFIT1interactor60.7330.638TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
DUF4268 (PF14088, IPR025364): Domain of unknown function (DUF4268)
TPR_19 (PF14559): Tetratricopeptide repeat
84 IFIT2interactor80.6432.037TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein
85 IFIT3interactor130.45518.716TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
86 IGBP1interactor120.24226.797TAP42 (PF04177, IPR007304): TAP42-like family
87 IGSF8oncoprotein380.51636.775V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
88 IKBKEinteractor40.6670.333IncA (PF04156, IPR007285): IncA protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
89 IL7Rinteractor230.39119.031fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
90 ILF3oncoprotein720.467308.445dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
91 ITCHinteractor110.4227.072C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
92 ITGA4interactor640.377267.173FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
93 KINinteractor31.0000KOW (PF00467, IPR005824, SM00739): KOW motif
SecM (PF06558, IPR009502): Secretion monitor precursor protein (SecM)
Kin17_mid (PF10357, IPR019447): Domain of Kin17 curved DNA-binding protein
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
94 LUC7L2protein found in more fusions340.369129.561LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
95 MAELinteractor70.5242.117HMG_box_2 (PF09011, IPR009071): HMG-box domain
Maelstrom (PF13017, IPR024970): piRNA pathway germ-plasm component
96 MAPKAPK2oncoprotein80.6672.195Pkinase (PF00069, IPR000719): Protein kinase domain
97 MCM2oncoprotein840.351573.986AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
98 MEX3Ainteractor21.0000KH_1 (PF00013, IPR004088, SM00322): KH domain
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
99 MEX3Binteractor30.6670.400KH_1 (PF00013, IPR004088, SM00322): KH domain
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
100 MEX3Cinteractor100.3789.124KH_1 (PF00013, IPR004088, SM00322): KH domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
101 MIFoncoprotein120.5824.018MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
102 MKRN1interactor50.7001.487Opy2 (PF09463, IPR018571): Opy2 protein
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
CD52 (PF15116, IPR026643): CAMPATH-1 antigen
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
Torus (PF16131, IPR032297): Torus domain
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
103 MSI2oncoprotein110.5643.498NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
104 NCLprotein found in more fusions700.410350.929DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
105 NDRG1suppressor190.46825.201Ndr (PF03096, IPR004142): Ndr family
106 NEDD8interactor400.57462.212ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
107 NFX1interactor120.6972.209R3H (PF01424, IPR001374, SM00393): R3H domain
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
108 NTRK1oncoprotein1110.2321831.872I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
109 OBSL1interactor650.333267.494BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
110 ORC4interactor50.5000.452AAA_16 (PF13191): AAA ATPase domain
ORC4_C (PF14629, IPR032705): Origin recognition complex (ORC) subunit 4 C-terminus
111 P4HBinteractor250.33747.694Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
112 PAIP1interactor110.47314.360MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
113 PAIP2suppressor80.3937.308PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
114 PAIP2Binteractor30.6670.100OB_RNB (PF08206, IPR013223): Ribonuclease B OB domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
115 PAN2interactor560.375346.827RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
116 PAN3interactor70.5243.544Pkinase (PF00069, IPR000719): Protein kinase domain
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
117 PAPOLAinteractor70.6671.959PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain
PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
118 PAPOLBinteractor31.0000PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain
PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain
119 PCBP1oncoprotein400.360141.804Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
120 PCBP2protein found in more fusions350.40675.525Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
121 PDCD6oncoprotein200.40926.153EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
122 PFASinteractor70.3335.465AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
123 PHGDHinteractor200.5796.5662-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
124 PIN1suppressor180.39222.127Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
125 PINX1suppressor70.4764.199G-patch (PF01585, IPR000467, SM00443): G-patch domain
NR_Repeat (PF14046, IPR025900): Nuclear receptor repeat
126 PLRG1interactor90.7781.373WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
127 POLEinteractor60.6001.208DNA_pol_B (PF00136, IPR006134): DNA polymerase family B
DNA_pol_B_exo1 (PF03104, IPR006133): DNA polymerase family B, exonuclease domain
DUF1744 (PF08490, IPR013697, SM01159): Domain of unknown function (DUF1744)
DNA_pol_B_exo2 (PF10108, IPR019288): Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
zf-RRPl_C4 (PF17026, IPR031502): Putative ribonucleoprotein zinc-finger pf C4 type
128 PPP2CAsuppressor200.24755.409Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
129 PREPinteractor40.5000.390Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
Peptidase_S9_N (PF02897, IPR023302): Prolyl oligopeptidase, N-terminal beta-propeller domain
130 PRMT6interactor21.0000Methyltransf_25 (PF13649): Methyltransferase domain
131 PRPF3protein found in more fusions190.42525.533DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115)
PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3)
PWI (PF01480, IPR002483, SM00311): PWI domain
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
132 PRPF8oncoprotein470.360159.068PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
133 PSMD9interactor80.4299.564Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
PDZ_2 (PF13180, IPR001478): PDZ domain
134 PUF60protein found in more fusions230.55019.246RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Titin_Z (PF09042, IPR015129): Titin Z
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
135 PXNoncoprotein60.7331.200LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
136 R3HCC1Linteractor21.0000NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
UPF0561 (PF10573, IPR018888): Uncharacterised protein family UPF0561
137 RACK1suppressor510.509114.358WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
138 RAE1interactor170.41219.854Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
139 RALYinteractor230.6967.790RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
140 RBM4suppressor250.54014.010RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
CompInhib_SCIN (PF11546, IPR021612): Staphylococcal complement inhibitor SCIN
141 RBM8Ainteractor220.23385.764RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
142 RPA1suppressor520.420210.387Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
143 RPA2oncoprotein440.451119.518RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
144 RPA3interactor390.49251.290Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
145 RPL10suppressor590.608148.412Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
146 RPL10Ainteractor580.70239.070Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
147 RPL11suppressor670.601136.512Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
148 RPL13interactor600.64665.060Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
149 RPL13Ainteractor510.71234.980Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
150 RPL14interactor590.66057.805KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
151 RPL15interactor670.60492.855Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
152 RPL17interactor490.74529.097Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
153 RPL18interactor720.569115.335Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
154 RPL18Ainteractor530.68841.537Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
155 RPL27protein found in more fusions470.76921.712Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
156 RPL27Ainteractor510.70739.426Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
157 RPL3interactor600.65576.432Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
158 RPL35interactor500.71232.965Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
XFP_N (PF09364, IPR018970): XFP N-terminal domain
159 RPL37Aprotein found in more fusions480.70254.580Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
160 RPL39interactor50.8000.222Ribosomal_L39 (PF00832, IPR000077): Ribosomal L39 protein
161 RPL4interactor770.513240.958Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
162 RPL5suppressor690.61584.018Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
163 RPL6protein found in more fusions770.515189.804Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
164 RPL7interactor670.62475.388Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
165 RPL7Aprotein found in more fusions660.588101.885Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
166 RPLP0interactor710.563118.156Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
167 RPLP2protein found in more fusions570.62966.619Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
168 RPS16interactor640.623113.804Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
169 RPS21interactor410.75225.727Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
170 RPS28interactor410.65745.162Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
171 RPS3Ainteractor750.559181.686Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
172 RPS4Xinteractor750.548171.966KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
173 RPS6protein found in more fusions720.577143.571Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
174 RPS8interactor720.586100.184Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
175 RPSAinteractor650.528220.548Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
176 RUVBL1oncoprotein300.37274.795TIP49 (PF06068, IPR010339): TIP49 C-terminus
177 SART1interactor300.49041.663SART-1 (PF03343, IPR005011): SART-1 family
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
178 SERBP1protein found in more fusions280.45042.092HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
179 SF3A1interactor330.43979.505TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
180 SFNsuppressor390.421100.85214-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
181 SGTAinteractor50.6001.549TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
XPC-binding (PF09280, IPR015360): XPC-binding domain
TPR_17 (PF13431): Tetratricopeptide repeat
SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
182 SH3KBP1protein found in more fusions120.25520.864Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
183 SIRT7interactor550.325268.900DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
184 SKIoncoprotein160.6294.948c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
SlyX (PF04102, IPR007236): SlyX
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
185 SKIV2L2interactor180.51615.683DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DSHCT (PF08148, IPR012961, SM01142): DSHCT (NUC185) domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain
186 SMAD3oncoprotein230.31269.377MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
187 SMG1interactor90.6793.040Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
SMG1 (PF15785, IPR031559): Serine/threonine-protein kinase smg-1
188 SMG6oncoprotein60.7002.333EST1 (PF10374, IPR019458): Telomerase activating protein Est1
EST1_DNA_bind (PF10373, IPR018834): Est1 DNA/RNA binding domain
PIN_4 (PF13638, IPR002716): PIN domain
189 SNRNP200protein found in more fusions400.44967.430DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
190 SNRPAinteractor290.41861.241RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
191 SNRPD3interactor400.283156.039LSM (PF01423, IPR001163): LSM domain
192 SNU13interactor310.64121.245Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
193 SNW1protein found in more fusions560.329330.556SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
194 SREK1protein found in more fusions170.5427.391Ureide_permease (PF07168, IPR009834): Ureide permease
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
195 SRPK1interactor260.49537.233FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
196 SRPK2oncoprotein310.347101.063DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
197 STAU1protein found in more fusions550.51376.545dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
198 SUMO1interactor80.6193.843Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
199 SYNCRIPinteractor570.371201.512RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
200 TARDBPinteractor800.367445.645RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
201 TDRD3interactor70.4293.938RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
DUF3472 (PF11958, IPR021862): Domain of unknown function (DUF3472)
202 TERToncoprotein100.28920.745RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
203 TMOD3interactor110.36411.337Tropomodulin (PF03250, IPR004934): Tropomodulin
Usher (PF00577, IPR000015): Outer membrane usher protein
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
204 TNRC6Ainteractor100.44411.002CreD (PF06123, IPR010364): Inner membrane protein CreD
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Ago_hook (PF10427, IPR019486): Argonaute hook
M_domain (PF12938, IPR026805): M domain of GW182
TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
205 TNRC6Binteractor150.44830.707DUF1421 (PF07223, IPR010820): Protein of unknown function (DUF1421)
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Ago_hook (PF10427, IPR019486): Argonaute hook
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
RRM_occluded (PF16842, IPR031766): Occluded RNA-recognition motif
206 TNRC6Cinteractor110.45510.150RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Ago_hook (PF10427, IPR019486): Argonaute hook
DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439)
M_domain (PF12938, IPR026805): M domain of GW182
DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
207 TOB1interactor70.3815.466PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
BTG (PF07742, IPR002087, SM00099): BTG family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
208 TOB2oncoprotein70.5243.958PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
BTG (PF07742, IPR002087, SM00099): BTG family
209 TP53suppressor790.282810.451DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
210 TSG101suppressor110.44412.259APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
211 U2AF1oncoprotein260.55131.773DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
212 U2AF2protein found in more fusions630.374259.423RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
213 UAP1interactor40.6670.065UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
214 UBA1protein found in more fusions150.31913.394ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
215 UBL4Ainteractor460.55075.342ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
216 UBR5protein found in more fusions210.24781.317CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SDA1 (PF05285, IPR007949): SDA1
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
217 UPF1interactor370.396168.721UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain)
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
218 USP10protein found in more fusions100.7222.357PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD
219 VCAM1interactor630.375194.889C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
220 WBP4interactor80.6791.417CDC45 (PF02724, IPR003874): CDC45-like protein
WW (PF00397, IPR001202, SM00456): WW domain
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
TMCO5 (PF14992, IPR026617): TMCO5 family
221 WWOXsuppressor220.32551.442adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
222 WWP2interactor60.6001.702WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
223 XPO1interactor650.223842.441CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
224 YWHAGprotein found in more fusions310.287132.57414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
225 ZFP36suppressor60.4003.228zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
226 ZMYND11suppressor90.4642.461DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002)
DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353)
PWWP (PF00855, IPR000313, SM00293): PWWP domain
zf-MYND (PF01753, IPR002893): MYND finger
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 HLA-DQB1interactorMHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
2 PABPC1parental proteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT

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