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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: DA327424 is the fusion of parental proteins PAXIP1, MBP (from a repository: Sat Feb 18 00:02:46 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)300
The number (and %) of the onco-proteins80 (26.67 %)
The number (and %) of the tumor suppressors32 (10.67 %)
Total number of binary PPIs (saturation %)1600 (3.57 %)
The number (and %) of affected PPIs299 (18.69 %)
The number of possible different fusions47
PPI diameter2
PPI radius1
The average degree of PPI10.000
Assortativity coefficient-0.2646
The network average Clustering coefficient0.478
The number (and %) of a zero Clustering coefficients33 (11.00 %)
The number (and %) of a zero Betweenness Centrality69 (23.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: PAXIP1,MBP All fusions
: DA327424;
Proteins found in more fusions STAU1 (see 2 fusions); MAPK1 (see 1 fusions); S100A8 (see 3 fusions); HIPK2 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); PIAS2 (see 2 fusions); LGALS3 (see 2 fusions); PRKDC (see 3 fusions); CCDC88A (see 3 fusions); PIAS1 (see 2 fusions); ULK1 (see 2 fusions); TLK1 (see 1 fusions); TRAPPC8 (see 1 fusions); EP300 (see 1 fusions); MAP3K5 (see 1 fusions); LRRK2 (see 1 fusions); PRDX6 (see 1 fusions); PRPF40A (see 2 fusions); RPA1 (see 1 fusions); STK3 (see 1 fusions); STRAP (see 2 fusions); CLU (see 5 fusions); LIMK1 (see 1 fusions); SUZ12 (see 2 fusions); APP (see 4 fusions); SRSF2 (see 1 fusions); G3BP1 (see 1 fusions); LUC7L2 (see 2 fusions); PRMT5 (see 2 fusions); SH3GL2 (see 1 fusions); ASH2L/DPY30 (see 1 fusions); HNRNPLL (see 1 fusions); TPM3 (see 2 fusions); ATXN1 (see 3 fusions); A2M (see 2 fusions); SQSTM1 (see 5 fusions); NCOA6 (see 1 fusions); MAPK14 (see 1 fusions); PCBP2 (see 3 fusions); RACK1 (see 3 fusions); SRSF1 (see 1 fusions); DKC1 (see 2 fusions); CSNK2A1 (see 1 fusions); ATN1 (see 1 fusions); MAPRE2 (see 1 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DA327424chimera2990.02773310.996BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
Myelin_MBP (PF01669, IPR000548): Myelin basic protein
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
2 A2Mprotein found in more fusions110.48917.050A2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
MP (PF01107, IPR028919): Viral movement protein (MP)
SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
3 AAMPinteractor40.5001.867PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
4 AASDHPPTinteractor30.6671.000ACPS (PF01648, IPR008278): 4'-phosphopantetheinyl transferase superfamily
5 ABL1oncoprotein90.32112.308Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
6 ALYREFinteractor180.44129.419FYTT (PF07078, IPR009782): Forty-two-three protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
7 ANAPC1suppressor110.9270.797PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
ANAPC1 (PF12859, IPR024990): Anaphase-promoting complex subunit 1
8 ANAPC4interactor150.62614.167ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ANAPC4 (PF12896, IPR024790): Anaphase-promoting complex, cyclosome, subunit 4
9 ANAPC5interactor120.8482.284TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
10 ANAPC7interactor140.8083.199TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
11 APPprotein found in more fusions660.0601747.882APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
12 APTXinteractor100FHA (PF00498, IPR000253, SM00240): FHA domain
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
13 ASH2Lprotein found in more fusions190.45840.549SPRY (PF00622, IPR003877, SM00449): SPRY domain
PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
14 ATN1protein found in more fusions40.6671.000Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
15 ATP1B1interactor40.5002.667Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
16 ATP1B3interactor100Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
17 ATXN1protein found in more fusions90.28619.000AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
18 BABAM1interactor80.60710.667VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
19 BCLAF1oncoprotein160.32539.688API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Apis_Csd (PF11671, IPR021007): Complementary sex determiner protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
20 BLMsuppressor120.41820.037BDHCT (PF08072, IPR012532): BDHCT (NUC031) domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
HRDC (PF00570, IPR002121, SM00341): HRDC domain
RQC (PF09382, IPR018982, SM00956): RQC domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
ALMT (PF11744, IPR020966): Aluminium activated malate transporter
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
BLM_N (PF16202, IPR032437): N-terminal region of Bloom syndrome protein
BDHCT_assoc (PF16204, IPR032439): BDHCT-box associated domain on Bloom syndrome protein
21 BRCC3interactor90.60710.333JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
22 BREoncoprotein61.0000BRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE)
23 BTBD16interactor100BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
24 BTBD6interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
PHR (PF08005, IPR012983): PHR domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
25 C2orf42interactor100zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
26 C7orf50interactor30.6670.250DUF2373 (PF10180, IPR019327): Uncharacterised conserved protein (DUF2373)
27 CABYRinteractor100RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
SPATA3 (PF15662, IPR026717): Spermatogenesis-associated protein 3 family
28 CAPZA1interactor120.42422.626F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
29 CAPZBinteractor80.5715.652Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
30 CARMIL2interactor100LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
CARMIL_C (PF16000, IPR031943): CARMIL C-terminus
31 CATSPERGinteractor100CATSPERG (PF15064, IPR028246): Cation channel sperm-associated protein subunit gamma
32 CBX8interactor200.25784.000Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RBR (PF17208): RNA binding Region
CBX7_C (PF17218): CBX family C-terminal motif
33 CCDC88Aprotein found in more fusions31.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
HOOK (PF05622, IPR008636): HOOK protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
34 CCNB2interactor60.4006.389Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
35 CCNDBP1suppressor21.0000CheF-arch (PF04283, IPR007381): Chemotaxis signal transduction system protein F from archaea
GCIP (PF13324): Grap2 and cyclin-D-interacting
36 CCNKinteractor60.5335.500Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
37 CCT6Binteractor60.4676.333Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
38 CD2BP2interactor50.4004.119GYF (PF02213, IPR003169, SM00444): GYF domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
39 CDC16interactor140.68115.446Dynein_light (PF01221, IPR001372): Dynein light chain type 1
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
40 CDC20oncoprotein180.52928.418WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
41 CDC23interactor150.69212.385ANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23
DUF772 (PF05598, IPR008490): Transposase domain (DUF772)
Menin (PF05053, IPR007747): Menin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
42 CDC27oncoprotein150.68110.968TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
43 CDC5Linteractor580.1281056.237OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
44 CDK1oncoprotein220.176126.293Pkinase (PF00069, IPR000719): Protein kinase domain
45 CDK12oncoprotein80.42910.648Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
Mem_trans (PF03547, IPR004776): Membrane transport protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SOBP (PF15279, IPR026092): Sine oculis-binding protein
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
46 CDK5oncoprotein60.8001.333Pkinase (PF00069, IPR000719): Protein kinase domain
47 CDK7oncoprotein100.36115.488Pkinase (PF00069, IPR000719): Protein kinase domain
48 CDK8interactor110.31122.467Pkinase (PF00069, IPR000719): Protein kinase domain
49 CDK9protein found in more fusions150.25345.775Pkinase (PF00069, IPR000719): Protein kinase domain
50 CENPUinteractor21.0000Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
XhlA (PF10779, IPR019715): Haemolysin XhlA
CENP-U (PF13097, IPR025214): CENP-A nucleosome associated complex (NAC) subunit
51 CIRBPoncoprotein80.39311.129RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
52 CLTConcoprotein140.23158.475Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
53 CLUsuppressor70.4672.021Clusterin (PF01093, IPR000753): Clusterin
54 COMTD1interactor100FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
55 COPEinteractor60.5003.467Coatomer_E (PF04733, IPR006822): Coatomer epsilon subunit
TPR_19 (PF14559): Tetratricopeptide repeat
56 CPSF3interactor60.4007.333Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily
RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF73-100_C (PF11718, IPR021718, SM01098): Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
57 CRIPAKinteractor100AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog)
Phage_Coat_B (PF05356, IPR008020): Phage Coat protein B
SEC-C (PF02810, IPR004027): SEC-C motif
zf-HIT (PF04438, IPR007529): HIT zinc finger
KAAG1 (PF15354, IPR029407): Kidney-associated antigen 1
58 CSNK2A1oncoprotein410.165437.508Pkinase (PF00069, IPR000719): Protein kinase domain
59 CSNK2Binteractor270.175196.214CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
60 CTDSP1interactor100NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
61 CYB5R4oncoprotein100CS (PF04969, IPR007052): CS domain
Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
FAD_binding_6 (PF00970, IPR008333): Oxidoreductase FAD-binding domain
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
62 DCAF13interactor21.0000eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
Sof1 (PF04158, IPR007287): Sof1-like domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
63 DCP1Ainteractor40.5002.333DCP1 (PF06058, IPR010334): Dcp1-like decapping family
mRNA_decap_C (PF16741, IPR031953): mRNA-decapping enzyme C-terminus
64 DDX18interactor110.36425.682DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF4217 (PF13959, IPR025313, SM01178): Domain of unknown function (DUF4217)
65 DDX23interactor70.28610.887DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3698 (PF12479, IPR022167): Protein of unknown function (DUF3698)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
66 DDX52interactor21.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal
67 DDX58suppressor60.5004.400DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
RIG-I_C-RD (PF11648, IPR021673): C-terminal domain of RIG-I
AAA_22 (PF13401, IPR003593): AAA domain
Syntaxin_2 (PF14523): Syntaxin-like protein
CARD_2 (PF16739, IPR031964): Caspase recruitment domain
68 DIS3Linteractor40.6670.952RNB (PF00773, SM00955): RNB domain
Rrp44_CSD1 (PF17216): Rrp44-like cold shock domain
Rrp44_S1 (PF17215): S1 domain
69 DKC1oncoprotein110.44416.376DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain
PUA (PF01472, IPR002478, SM00359): PUA domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
70 DNAJA1interactor120.25839.002DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
71 DNAJB11interactor30.6671.000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
72 DPY30protein found in more fusions140.38533.656Dpy-30 (PF05186, IPR007858): Dpy-30 motif
73 DRG1interactor60.6003.267MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TGS (PF02824, IPR004095): TGS domain
MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain
74 DYNC2H1interactor100AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1
DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2
DUF1366 (PF07104, IPR009796): Protein of unknown function (DUF1366)
DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
Laminin_II (PF06009, IPR010307): Laminin Domain II
AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1
AAA_7 (PF12775): P-loop containing dynein motor region D3
MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor
AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4
AAA_9 (PF12781): ATP-binding dynein motor region D5
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
75 EBNA1BP2interactor70.6196.833Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
76 ECSITinteractor70.7334.000ECSIT (PF06239, IPR010418): Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C (PF14784, IPR029342): C-terminal domain of the ECSIT protein
77 EIF2S2interactor110.40012.792DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5
Cytochrom_c3_2 (PF14537): Cytochrome c3
78 EIF3Hinteractor120.40924.395Androgen_recep (PF02166, IPR001103): Androgen receptor
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
NHS (PF15273, IPR024845): NHS-like
79 EIF3Ioncoprotein100.46713.152ISN1 (PF06437, IPR009453): IMP-specific 5'-nucleotidase
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
80 EIF5Binteractor60.5333.467GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
MIase (PF02426, IPR026029): Muconolactone delta-isomerase
NOA36 (PF06524, IPR010531): NOA36 protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
IF-2 (PF11987, IPR023115): Translation-initiation factor 2
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
GTP_EFTU_D4 (PF14578, IPR029459): Elongation factor Tu domain 4
DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632)
Coilin_N (PF15862, IPR031722): Coilin N-terminus
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
81 ELAVL1oncoprotein610.1111236.151RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
82 EMDinteractor130.22736.175LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
83 EP300oncoprotein410.158498.981Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
84 EPB41L3suppressor110.41820.4094_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SAB (PF04382, IPR007477): SAB domain
85 ERFsuppressor30.6670.333CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Ets (PF00178, IPR000418, SM00413): Ets-domain
MCPVI (PF02993, IPR004243): Minor capsid protein VI
86 ERHinteractor60.5333.929ER (PF01133, IPR000781): Enhancer of rudimentary
87 FAHD1interactor31.0000FAA_hydrolase (PF01557, IPR002529): Fumarylacetoacetate (FAA) hydrolase family
88 FAM175Ainteractor61.0000DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
89 FAM96Binteractor21.0000DUF59 (PF01883, IPR002744): Domain of unknown function DUF59
90 FBLN5interactor21.0000EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
91 FEN1oncoprotein100.35618.5555_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
92 FUCA1interactor21.0000Alpha_L_fucos (PF01120, IPR000933, SM00812): Alpha-L-fucosidase
Fucosidase_C (PF16757, IPR031919): Alpha-L-fucosidase C-terminal domain
93 G3BP1protein found in more fusions110.24424.363NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
94 GCLCinteractor21.0000GCS (PF03074, IPR004308): Glutamate-cysteine ligase
95 GPATCH4interactor100G-patch (PF01585, IPR000467, SM00443): G-patch domain
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239)
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
96 GPKOWinteractor30.6670.133KOW (PF00467, IPR005824, SM00739): KOW motif
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
97 GTF3C5interactor30.6670.182Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
Tau95 (PF09734, IPR019136): RNA polymerase III transcription factor (TF)IIIC subunit
98 H1FXinteractor40.6670.432IGPS (PF00218, IPR013798): Indole-3-glycerol phosphate synthase
99 H2AFXsuppressor230.237136.526Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
100 HIPK2suppressor50.6671.400Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
101 HIST1H3Ainteractor220.243127.095Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
102 HLA-DRAinteractor21.0000MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
103 HNRNPLLprotein found in more fusions50.5002.667RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
104 HP1BP3interactor80.4296.583RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SDA1 (PF05285, IPR007949): SDA1
YL1 (PF05764, IPR008895): YL1 nuclear protein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
105 HSPA14interactor21.0000HSP70 (PF00012, IPR013126): Hsp70 protein
106 HSPA4Linteractor30.6670.500HSP70 (PF00012, IPR013126): Hsp70 protein
107 IKBKEinteractor50.6672.000IncA (PF04156, IPR007285): IncA protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
108 INTS7interactor100DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
HEAT_2 (PF13646): HEAT repeats
FANCI_S2 (PF14676, IPR026171): FANCI solenoid 2
SPG48 (PF14764, IPR028222): AP-5 complex subunit, vesicle trafficking
109 IRAK4interactor100Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
110 KDM1Binteractor50.5003.833Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
SWIRM (PF04433, IPR007526): SWIRM domain
111 KDM6Asuppressor90.8062.249JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
112 KIF2Cinteractor100.33318.539Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
113 KMT2Boncoprotein100.55614.702FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
GRP (PF07172, IPR010800): Glycine rich protein family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
114 KMT2Csuppressor120.57613.887AT_hook (PF02178, IPR017956, SM00384): AT hook motif
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
SLC12 (PF03522, IPR018491): Solute carrier family 12
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
115 KMT2Doncoprotein70.8101.900DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Mnd1 (PF03962, IPR005647): Mnd1 family
PHD (PF00628, IPR019787, SM00249): PHD-finger
Pox_F17 (PF04767, IPR006854): DNA-binding 11 kDa phosphoprotein
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
SET (PF00856, IPR001214, SM00317): SET domain
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
Fer4_4 (PF12800, IPR001450): 4Fe-4S binding domain
DUF4163 (PF13739, IPR025303): Domain of unknown function (DUF4163)
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
Hydin_ADK (PF17213): Hydin Adenylate kinase-like domain
116 KRI1interactor30.6670.667Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
Vpu (PF00558, IPR008187): Vpu protein
Kri1 (PF05178, IPR018034): KRI1-like family
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Kri1_C (PF12936, IPR024626): KRI1-like family C-terminal
117 KRR1interactor110.47319.117Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
KH_1 (PF00013, IPR004088, SM00322): KH domain
118 LACTBoncoprotein40.6671.000Beta-lactamase (PF00144, IPR001466): Beta-lactamase
119 LARP1interactor80.7141.587La (PF05383, IPR006630, SM00715): La domain
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
120 LARP7interactor90.44412.190Agouti (PF05039, IPR007733, SM00792): Agouti protein
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
La (PF05383, IPR006630, SM00715): La domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
121 LDHAinteractor100.36115.729Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
122 LDHBinteractor130.31832.496Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
123 LGALS3oncoprotein110.33321.422Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
124 LIMA1suppressor100.42215.402LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
125 LIMK1oncoprotein70.5334.762LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
126 LIMK2interactor40.5002.667LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
PP1_inhibitor (PF05361, IPR008025): PKC-activated protein phosphatase-1 inhibitor
127 LRRK2oncoprotein160.18170.633Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
128 LUC7L2protein found in more fusions210.42152.218LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
129 LYARinteractor50.4004.900DEK_C (PF08766, IPR014876): DEK C terminal domain
zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger
DUF3499 (PF12005, IPR021888): Protein of unknown function (DUF3499)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
130 MAP3K3oncoprotein50.6671.400PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
131 MAP3K5oncoprotein40.6670.250Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
132 MAP4K4interactor60.3336.686CNH (PF00780, IPR001180, SM00036): CNH domain
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Pkinase (PF00069, IPR000719): Protein kinase domain
FAM165 (PF14981, IPR028023): FAM165 family
SOBP (PF15279, IPR026092): Sine oculis-binding protein
FAM60A (PF15396, IPR026065): Protein Family FAM60A
133 MAPK1oncoprotein160.22962.267Pkinase (PF00069, IPR000719): Protein kinase domain
134 MAPK11interactor50.6003.000HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Pkinase (PF00069, IPR000719): Protein kinase domain
135 MAPK12oncoprotein50.4004.833Pkinase (PF00069, IPR000719): Protein kinase domain
Peripla_BP_5 (PF13433): Periplasmic binding protein domain
136 MAPK13oncoprotein40.5001.556Pkinase (PF00069, IPR000719): Protein kinase domain
137 MAPK14oncoprotein160.22963.306Pkinase (PF00069, IPR000719): Protein kinase domain
138 MAPK3oncoprotein100.30619.900Pkinase (PF00069, IPR000719): Protein kinase domain
139 MAPRE2protein found in more fusions50.5001.833ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
140 MAST1interactor80.7143.967DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
141 MCM6interactor80.3817.919MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
YmgB (PF10798, IPR024753): Biofilm development protein YmgB/AriR
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
142 MDC1suppressor510.151844.303FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
143 MED23interactor110.32725.397Med23 (PF11573, IPR021629): Mediator complex subunit 23
144 MELKinteractor50.5002.333KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
145 MGEA5oncoprotein80.42912.917NAGidase (PF07555, IPR011496): beta-N-acetylglucosaminidase
146 MOB4interactor50.9000.500Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
147 MRE11Aoncoprotein180.44136.033APG6 (PF04111, IPR007243): Autophagy protein Apg6
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain
148 MRM3interactor21.0000SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family
SpoU_sub_bind (PF08032, IPR013123, SM00967): RNA 2'-O ribose methyltransferase substrate binding
149 MT2Asuppressor100Metallothio (PF00131, IPR003019): Metallothionein
150 MTIF3interactor21.0000IF3_C (PF00707, IPR019815): Translation initiation factor IF-3, C-terminal domain
IF3_N (PF05198, IPR019814): Translation initiation factor IF-3, N-terminal domain
151 MUS81suppressor30.6671.000ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
MutL (PF13941, IPR006230): MutL protein
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
152 MYH6interactor30.6671.000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
153 MYL12Ainteractor31.0000EF-hand_11 (PF08976, IPR015070): EF-hand domain
DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
154 MYO1Dinteractor40.6671.333IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
155 NANOGinteractor170.24255.872Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
156 NBNsuppressor150.46727.548FHA (PF00498, IPR000253, SM00240): FHA domain
Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1
NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
157 NCAPD2oncoprotein80.4647.321Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein
HEAT (PF02985, IPR000357): HEAT repeat
LrgA (PF03788, IPR005538): LrgA family
Proteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
158 NCAPD3interactor50.4002.433DUF3013 (PF11217, IPR021380): Protein of unknown function (DUF3013)
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
159 NCAPGinteractor60.5335.000P16-Arc (PF04699, IPR006789): ARP2/3 complex 16 kDa subunit (p16-Arc)
Terminase_2 (PF03592, IPR005335): Terminase small subunit
UVR (PF02151, IPR001943): UvrB/uvrC motif
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
HEAT_2 (PF13646): HEAT repeats
160 NCOA6oncoprotein160.46731.348DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Presenilin (PF01080, IPR001108): Presenilin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
161 NME4interactor31.0000NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
162 NOL7suppressor21.0000NUC129 (PF08157, IPR012579): NUC129 domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal
163 NOM1interactor100HSP90 (PF00183, IPR001404): Hsp90 protein
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
164 NOP14interactor21.0000Nop14 (PF04147, IPR007276): Nop14-like family
165 NOP2interactor130.38528.556BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
166 NOP9interactor100PUF (PF00806, IPR001313, SM00025): Pumilio-family RNA binding repeat
167 NOS3interactor90.50010.595FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
HTH_15 (PF12324, IPR024259): Helix-turn-helix domain of alkylmercury lyase
168 NPC2interactor100E1_DerP2_DerF2 (PF02221, IPR003172, SM00737): ML domain
169 NXT1interactor31.0000NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
170 PAGR1interactor90.6944.400PAXIP1_C (PF15364, IPR028213): PAXIP1-associated-protein-1 C term PTIP binding protein
171 PAX2oncoprotein100PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Pax2_C (PF12403, IPR022130): Paired-box protein 2 C terminal
172 PCBP2protein found in more fusions110.42214.331Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
173 PCYT1Binteractor21.0000ApoC-I (PF04691, IPR006781): Apolipoprotein C-I (ApoC-1)
CTP_transf_like (PF01467, IPR004821): Cytidylyltransferase-like
FTO_CTD (PF12934, IPR024366): FTO C-terminal domain
174 PDCD11interactor40.6672.000DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
175 PELOinteractor70.4295.795eRF1_1 (PF03463, IPR005140): eRF1 domain 1
eRF1_2 (PF03464, IPR005141): eRF1 domain 2
eRF1_3 (PF03465, IPR005142): eRF1 domain 3
176 PER1oncoprotein31.0000PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
SPX (PF03105, IPR004331): SPX domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region
177 PGAM5interactor40.5001.389His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
178 PGGHGoncoprotein100Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
DUF2152 (PF10222, IPR018795): Uncharacterized conserved protein (DUF2152)
179 PGM1interactor60.4006.400PGM_PMM_I (PF02878, IPR005844): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879, IPR005845): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880, IPR005846): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408, IPR005843): Phosphoglucomutase/phosphomannomutase, C-terminal domain
180 PHAXinteractor40.6671.286RNA_GG_bind (PF10258, IPR019385): PHAX RNA-binding domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
181 PHB2interactor90.36114.700DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
182 PIAS1suppressor100.30617.420Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
183 PIAS2protein found in more fusions50.5003.000SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
184 PKN1interactor70.5336.667C2 (PF00168, IPR000008, SM00239): C2 domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
185 PKP4interactor21.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
186 PLCD1suppressor21.0000C2 (PF00168, IPR000008, SM00239): C2 domain
EF-hand_like (PF09279, IPR015359): Phosphoinositide-specific phospholipase C, efhand-like
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
EF-hand_10 (PF14788): EF hand
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
187 PLP1interactor100Myelin_PLP (PF01275, IPR001614, SM00002): Myelin proteolipid protein (PLP or lipophilin)
188 POLR1Einteractor30.6671.000RNA_pol_I_A49 (PF06870, IPR009668): A49-like RNA polymerase I associated factor
189 POM121interactor21.0000Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
POM121 (PF15229): POM121 family
190 POU5F1oncoprotein200.20589.536Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
191 PPARGsuppressor150.29742.582zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
192 PPHLN1interactor60.4672.920Lge1 (PF11488): Transcriptional regulatory protein LGE1
HERV-K_REC (PF15695): Rec (regulator of expression encoded by corf) of HERV-K-113
193 PPIAinteractor100.35619.412Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
194 PPIHinteractor200Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
195 PPP1CConcoprotein210.186128.679Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
196 PPP1R12Ainteractor60.5334.067DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
AAA_23 (PF13476): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
GEMIN8 (PF15348): Gemini of Cajal bodies-associated protein 8
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
197 PPP2CAsuppressor150.27659.917Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
198 PPP2R5Csuppressor50.6001.650B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
DUF1616 (PF07760, IPR011674): Protein of unknown function (DUF1616)
199 PRDX6protein found in more fusions50.5001.352AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
200 PRKCAinteractor80.4766.705C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
201 PRKCBsuppressor70.5334.286C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
202 PRKCIinteractor80.4647.901PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
203 PRKCZinteractor70.4006.333PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
204 PRKDCprotein found in more fusions260.297120.890FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
205 PRMT5protein found in more fusions80.3819.833PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
206 PRPF40Aprotein found in more fusions180.27953.724FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
207 PRPSAP1interactor50.5001.733Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
208 PSMA6interactor50.4002.933Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
209 RAB3GAP1interactor21.0000Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Rab3-GTPase_cat (PF13890, IPR026147): Rab3 GTPase-activating protein catalytic subunit
210 RAB3GAP2interactor21.0000RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
RAB3GAP2_C (PF14656, IPR029257): Rab3 GTPase-activating protein regulatory subunit C-terminus
211 RACK1suppressor150.35236.615WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
212 RAD50interactor100.6676.252DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
YscO (PF07321, IPR009929): Type III secretion protein YscO
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
DUF2703 (PF10865, IPR021219): Domain of unknown function (DUF2703)
DUF3015 (PF11220, IPR021383): Protein of unknown function (DUF3015)
AAA_13 (PF13166, IPR026866): AAA domain
AAA_23 (PF13476): AAA domain
SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
DUF4795 (PF16043, IPR032013): Domain of unknown function (DUF4795)
213 RBBP5oncoprotein190.40552.941WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
214 RBBP7suppressor40.5001.310WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
215 RBM25interactor80.7142.308Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778)
216 RFC2interactor70.8101.198AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
AAA_16 (PF13191): AAA ATPase domain
AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
217 RFC4interactor100.53311.288AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Rad17 (PF03215): Rad17 cell cycle checkpoint protein
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
218 RNF32interactor90.7143.967IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
219 RPA1suppressor390.168419.776Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
220 RPL12interactor70.7142.138Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
221 RPS20interactor80.5716.769Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
222 RPS27Ainteractor50.5003.833DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
223 RPS6KA5interactor90.44411.693Choline_kinase (PF01633): Choline/ethanolamine kinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
224 RPS6KA6suppressor30.6670.667Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
225 S100A8oncoprotein50.6672.000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
226 SCAMP5interactor100SCAMP (PF04144, IPR007273): SCAMP family
227 SCCPDHinteractor40.5002.667Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain
228 SELENOVinteractor100DUF963 (PF06131, IPR009306): Schizosaccharomyces pombe repeat of unknown function (DUF963)
Rdx (PF10262, IPR011893): Rdx family
229 SH3GL2oncoprotein60.5003.333BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
230 SKA3interactor21.0000RNA_pol_RpbG (PF16992, IPR031555): DNA-directed RNA polymerase, subunit G
231 SLC1A5interactor21.0000SDF (PF00375, IPR001991): Sodium:dicarboxylate symporter family
232 SMAD2suppressor140.26941.556MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
233 SMC1Aoncoprotein140.34633.680SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
234 SMC2interactor100.42217.102SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
235 SMC3oncoprotein120.37923.864SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
236 SNRNP70interactor150.34336.325RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
237 SNRPD3interactor90.5835.788LSM (PF01423, IPR001163): LSM domain
238 SNX3interactor40.6671.286PX (PF00787, IPR001683, SM00312): PX domain
239 SOX30interactor100HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
240 SPAG4interactor100IncA (PF04156, IPR007285): IncA protein
Sad1_UNC (PF07738, IPR012919): Sad1 / UNC-like C-terminal
241 SPATA18interactor100Filament (PF00038, IPR001664): Intermediate filament protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
SOBP (PF15279, IPR026092): Sine oculis-binding protein
MIEAP (PF16026, IPR031981): Mitochondria-eating protein
242 SPOUT1interactor21.0000Methyltrn_RNA_3 (PF02598, IPR003750): Putative RNA methyltransferase
243 SQSTM1oncoprotein200.158111.205PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
244 SRP9interactor30.6670.667SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
245 SRPK1interactor250.260138.876FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
246 SRRM1interactor280.246170.221DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen
MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
PWI (PF01480, IPR002483, SM00311): PWI domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
247 SRRM2interactor250.293115.455cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
248 SRSF1protein found in more fusions250.38479.931Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
249 SRSF10interactor100.5785.439RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
250 SRSF2oncoprotein130.45514.393RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
251 SRSF4interactor100.6444.851Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
252 SRSF5interactor130.57712.110DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
253 SRSF7interactor170.46324.069RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-CCHC (PF00098, IPR001878): Zinc knuckle
254 SRSF9interactor120.42411.256RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
255 SSBinteractor140.31932.966HMA (PF00403, IPR006121): Heavy-metal-associated domain
La (PF05383, IPR006630, SM00715): La domain
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
256 STAU1protein found in more fusions360.192309.657dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
257 STK3protein found in more fusions90.39316.000Pkinase (PF00069, IPR000719): Protein kinase domain
Mst1_SARAH (PF11629, IPR024205): C terminal SARAH domain of Mst1
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
258 STK39interactor31.0000BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein)
FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
Pkinase (PF00069, IPR000719): Protein kinase domain
OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
259 STOML2oncoprotein50.6001.162Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4769 (PF15992, IPR031934): Domain of unknown function (DUF4769)
Band_7_C (PF16200, IPR032435): C-terminal region of band_7
260 STRAPprotein found in more fusions80.4766.282WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
261 STRNoncoprotein90.36119.733CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
262 STRN4interactor60.6674.500CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
263 SUGT1interactor30.6670.154CheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
264 SUZ12suppressor450.132599.599DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
265 TADA2Ainteractor150.41933.057SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
266 TARDBPinteractor290.204204.021RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
267 TBK1interactor80.38110.006DUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
268 TCN2interactor21.0000Cobalamin_bind (PF01122, IPR002157): Eukaryotic cobalamin-binding protein
DUF4430 (PF14478, IPR027954): Domain of unknown function (DUF4430)
269 TECRinteractor30.6671.000Steroid_dh (PF02544, IPR001104): 3-oxo-5-alpha-steroid 4-dehydrogenase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
270 THRAP3oncoprotein100.4899.559API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
271 TLK1protein found in more fusions50.6670.952Pkinase (PF00069, IPR000719): Protein kinase domain
Vir_act_alpha_C (PF10400, IPR018309): Virulence activator alpha C-term
272 TM2D3interactor100TM2 (PF05154, IPR007829): TM2 domain
273 TMEM120Ainteractor21.0000TMPIT (PF07851, IPR012926): TMPIT-like protein
274 TMPOinteractor100.33318.001LEM (PF03020, IPR003887, SM00540): LEM domain
Thymopoietin (PF08198, IPR013146): Thymopoietin protein
LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
275 TP53BP1suppressor310.206251.79953-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
276 TPM3oncoprotein90.39310.852Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
277 TRA2Ainteractor220.30397.381DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
278 TRA2Binteractor170.34641.196RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
279 TRAPPC8protein found in more fusions200TRAPPC-Trs85 (PF12739, IPR024420): ER-Golgi trafficking TRAPP I complex 85 kDa subunit
SNAP (PF14938): Soluble NSF attachment protein, SNAP
280 TRPM7interactor200Alpha_kinase (PF02816, IPR004166, SM00811): Alpha-kinase family
Ion_trans (PF00520, IPR005821): Ion transport protein
DUF3893 (PF13032, IPR024996): Domain of unknown function (DUF3893)
TRPM_tetra (PF16519, IPR032415): Tetramerisation domain of TRPM
281 TSSK6interactor40.6670.917Pkinase (PF00069, IPR000719): Protein kinase domain
282 U2SURPinteractor70.6672.110cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB)
Surp (PF01805, IPR000061, SM00648): Surp module
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
FAM176 (PF14851): FAM176 family
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637)
283 UIMC1suppressor140.29751.339Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
284 ULK1protein found in more fusions40.6670.667Pkinase (PF00069, IPR000719): Protein kinase domain
DUF3543 (PF12063, IPR022708): Domain of unknown function (DUF3543)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
285 UMPSinteractor60.4008.667OMPdecase (PF00215, IPR001754, SM00934): Orotidine 5'-phosphate decarboxylase / HUMPS family
Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
286 WDHD1interactor40.5002.000PVL_ORF50 (PF07768, IPR011688): PVL ORF-50-like family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
287 WDR18interactor60.6672.122WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif
288 WDR48suppressor60.6004.000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3337 (PF11816, IPR021772): Domain of unknown function (DUF3337)
289 WDR5interactor220.312111.798WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
290 WDR82oncoprotein130.51318.489MinC_C (PF03775, IPR005526): Septum formation inhibitor MinC, C-terminal domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
291 WEE1interactor60.6004.556Pkinase (PF00069, IPR000719): Protein kinase domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
292 XAGE1Einteractor100GAGE (PF05831, IPR008625): GAGE protein
293 XPO1interactor560.0831201.253CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
294 XRCC6oncoprotein200.28179.464Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
295 YBX1oncoprotein190.26969.610CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
296 YBX3interactor120.28828.759CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1)
297 ZBTB8Ainteractor40.6671.000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
298 ZNF251interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
299 ZNF280Binteractor21.0000PLATZ (PF04640, IPR006734): PLATZ transcription factor
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
DUF4195 (PF13836, IPR025243): Domain of unknown function (DUF4195)
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
300 ZNF622interactor70.5335.400S-antigen (PF05756, IPR008825): S-antigen protein
Stm1_N (PF09598, IPR019084): Stm1
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 LOC653602interactorNA
2 MBPparental proteinMyelin_MBP (PF01669, IPR000548): Myelin basic protein
3 MRPL33interactorNA
4 ND1interactorNA
5 PAXIP1parental proteinBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain

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