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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: CN275550 is the fusion of parental proteins TUBG1 (from a repository: Thu Jan 19 05:49:28 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)221
The number (and %) of the onco-proteins50 (22.62 %)
The number (and %) of the tumor suppressors26 (11.76 %)
Total number of binary PPIs (saturation %)2636 (10.84 %)
The number (and %) of affected PPIs220 (8.35 %)
The number of possible different fusions29
PPI diameter2
PPI radius1
The average degree of PPI23.394
Assortativity coefficient-0.2322
The network average Clustering coefficient0.562
The number (and %) of a zero Clustering coefficients8 (3.62 %)
The number (and %) of a zero Betweenness Centrality27 (12.22 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: TUBG1 All fusions
: CN275550;
Proteins found in more fusions CTBP1 (see 2 fusions); SYK (see 1 fusions); LGALS3BP (see 2 fusions); LAMP2 (see 1 fusions); YWHAH (see 2 fusions); YWHAZ (see 1 fusions); NDE1 (see 3 fusions); SAMHD1 (see 1 fusions); HNRNPU/RPL24 (see 1 fusions); RPLP2 (see 1 fusions); PRPF3 (see 1 fusions); SNW1 (see 1 fusions); APP (see 4 fusions); CUL4A (see 4 fusions); HSP90AA1 (see 2 fusions); HSP90AB1 (see 1 fusions); PPFIA1 (see 2 fusions); HSPA8/HSPD1 (see 1 fusions); EEF1A1 (see 1 fusions); MYC (see 1 fusions); ACTB (see 3 fusions); TP53 (see 3 fusions); PRDX4 (see 1 fusions); DSP (see 4 fusions); BAG2 (see 1 fusions); NDEL1 (see 1 fusions); EGFR (see 2 fusions); UBR5 (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CN275550chimera2200.09825655.579Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
2 ACTBoncoprotein270.36371.623Actin (PF00022, IPR004000, SM00268): Actin
3 AGRNinteractor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain
Laminin_G_1 (PF00054, IPR001791): Laminin G domain
NtA (PF03146, IPR004850): Agrin NtA domain
SEA (PF01390, IPR000082, SM00200): SEA domain
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Kazal_2 (PF07648, IPR002350, SM00280): Kazal-type serine protease inhibitor domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
EGF_3 (PF12947, IPR024731): EGF domain
4 APPprotein found in more fusions480.190549.904APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
5 ARMC5suppressor21.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
HEAT_EZ (PF13513): HEAT-like repeat
6 ARPC1Binteractor70.6191.427WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
7 AUP1interactor50.7000.380CUE (PF02845, IPR003892, SM00546): CUE domain
8 AURKAoncoprotein420.338199.545Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
9 BAG2protein found in more fusions150.59310.254IncA (PF04156, IPR007285): IncA protein
Mnd1 (PF03962, IPR005647): Mnd1 family
ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
10 BRCA1suppressor320.241185.373BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
11 CADoncoprotein220.51919.889Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MGS (PF02142, IPR011607, SM00851): MGS-like domain
OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
12 CAMK2Ginteractor31.0000CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain
Pkinase (PF00069, IPR000719): Protein kinase domain
13 CCDC8interactor540.273444.171Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
14 CCNE1oncoprotein70.5243.429Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
15 CCP110interactor70.5712.285DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
IFT20 (PF14931, IPR028172): Intraflagellar transport complex B, subunit 20
CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
CALM_bind (PF16025): Calcium-dependent calmodulin binding
16 CCT2interactor300.56341.782Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
17 CCT3interactor250.62023.110Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
18 CCT4interactor220.69312.470Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
19 CCT5interactor230.64817.247Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
20 CCT6Ainteractor230.68413.592Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
21 CCT7interactor220.66214.873Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
22 CCT8interactor250.63321.356Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
23 CDC20oncoprotein390.287202.955WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
24 CDC5Linteractor480.290273.545OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
25 CDK2suppressor800.281934.739Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
26 CDK5RAP2interactor90.6946.695APG6 (PF04111, IPR007243): Autophagy protein Apg6
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993)
IncA (PF04156, IPR007285): IncA protein
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
27 CDK5RAP3interactor50.7000.424DUF773 (PF05600, IPR008491): Protein of unknown function (DUF773)
28 CENPJinteractor80.4647.175DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein
Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
AAA_23 (PF13476): AAA domain
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
29 CEP250interactor610.411393.700ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
30 CLPTM1Linteractor30.6670.667CLPTM1 (PF05602, IPR008429): Cleft lip and palate transmembrane protein 1 (CLPTM1)
31 COL18A1oncoprotein21.0000Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF959 (PF06121, IPR010363): Domain of Unknown Function (DUF959)
Endostatin (PF06482, IPR010515): Collagenase NC10 and Endostatin
Fz (PF01392, IPR020067, SM00063): Fz domain
Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
32 COX4I1interactor30.6670.400COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV
33 CPS1interactor110.4739.246CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding
MGS (PF02142, IPR011607, SM00851): MGS-like domain
34 CPT1Ainteractor60.6670.702Carn_acyltransf (PF00755, IPR000542): Choline/Carnitine o-acyltransferase
CPT_N (PF16484, IPR032476): Carnitine O-palmitoyltransferase N-terminus
35 CSN3interactor100Casein_kappa (PF00997, IPR000117): Kappa casein
36 CTBP1protein found in more fusions90.5365.7112-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
37 CUL4Aprotein found in more fusions400.277223.292Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
38 CUL4Boncoprotein460.402224.851Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
39 DDA1interactor60.6003.022DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
40 DEUP1suppressor200APG6 (PF04111, IPR007243): Autophagy protein Apg6
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
CEP63 (PF17045, IPR031470): Centrosomal protein of 63 kDa
41 DNAJB1suppressor150.57111.168DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
42 DNAJB11interactor110.7271.774DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
43 DNMBPinteractor40.5000.847BAR (PF03114, IPR004148, SM00721): BAR domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
IncA (PF04156, IPR007285): IncA protein
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
44 DPM1interactor50.7000.225Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
45 DSC1interactor80.6434.135Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
UPF0114 (PF03350, IPR005134): Uncharacterized protein family, UPF0114
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
46 DSG1interactor80.5364.298Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
47 DSPsuppressor100.4727.516APG6 (PF04111, IPR007243): Autophagy protein Apg6
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
CLP_protease (PF00574, IPR023562): Clp protease
DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fez1 (PF06818): Fez1
FIVAR (PF07554, IPR011490): Uncharacterised Sugar-binding Domain
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
Rho_Binding (PF08912, IPR015008): Rho Binding
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
SOGA (PF11365, IPR027881): Protein SOGA
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
FAM184 (PF15665): Family with sequence similarity 184, A and B
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
48 DTLinteractor70.6194.833WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
49 EEF1A1suppressor530.438209.003GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
50 EEF1A2oncoprotein70.4292.400GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
51 EGFRoncoprotein540.231524.941Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
52 ESR1suppressor560.394351.776Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
53 FAF2interactor160.36231.548DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
54 FASTKD5interactor40.5000.306FAST_1 (PF06743, IPR010622): FAST kinase-like protein, subdomain 1
FAST_2 (PF08368, IPR013579): FAST kinase-like protein, subdomain 2
RAP (PF08373, IPR013584, SM00952): RAP domain
55 FBXO6interactor570.172663.700FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
56 FGF2oncoprotein21.0000FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
57 FGF3oncoprotein21.0000FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
58 FLGinteractor100Filaggrin (PF03516, IPR003303): Filaggrin
S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
Hid1 (PF12722): High-temperature-induced dauer-formation protein
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266)
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
59 FLIIoncoprotein70.6670.835Gelsolin (PF00626, IPR007123): Gelsolin repeat
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
60 GANABsuppressor80.5002.692Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
DUF5110 (PF17137): Domain of unknown function (DUF5110)
61 GCN1interactor150.40013.139Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
62 GTF2Iinteractor110.7272.373GTF2I (PF02946, IPR004212): GTF2I-like repeat
63 H2AFVinteractor40.8330.167Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
64 HADHAinteractor90.5006.5493HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
65 HADHBinteractor130.46215.904Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
66 HAUS2interactor220.22578.477DpnII (PF04556, IPR007637): DpnII restriction endonuclease
HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2
67 HECW2interactor130.27329.873C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
68 HELZinteractor21.0000PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
TetR_C_8 (PF14278): Transcriptional regulator C-terminal region
69 HIST1H4Hinteractor30.6670.087CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
70 HNRNPUprotein found in more fusions580.522254.726CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
71 HSP90AA1oncoprotein580.337407.513HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
72 HSP90AB1oncoprotein500.420169.789HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
73 HSPA1Ainteractor340.41578.966HSP70 (PF00012, IPR013126): Hsp70 protein
74 HSPA1Linteractor170.46313.583HSP70 (PF00012, IPR013126): Hsp70 protein
75 HSPA4interactor340.337171.758Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
76 HSPA5oncoprotein490.315297.226HSP70 (PF00012, IPR013126): Hsp70 protein
77 HSPA8oncoprotein480.363206.651HSP70 (PF00012, IPR013126): Hsp70 protein
78 HSPA9oncoprotein290.37461.324HSP70 (PF00012, IPR013126): Hsp70 protein
79 HSPD1suppressor250.50320.532Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
80 IKBKGinteractor160.52417.376CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
81 IRS4interactor180.37920.771CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
PH_11 (PF15413): Pleckstrin homology domain
82 KEAP1oncoprotein70.8000.869BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
83 LAMA1interactor21.0000Laminin_B (PF00052, IPR000034): Laminin B (Domain IV)
Laminin_G_1 (PF00054, IPR001791): Laminin G domain
Laminin_I (PF06008, IPR009254): Laminin Domain I
Laminin_II (PF06009, IPR010307): Laminin Domain II
Sec34 (PF04136, IPR007265): Sec34-like family
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
84 LAMA3interactor100Laminin_B (PF00052, IPR000034): Laminin B (Domain IV)
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
Laminin_I (PF06008, IPR009254): Laminin Domain I
Laminin_II (PF06009, IPR010307): Laminin Domain II
PPE (PF00823, IPR000030): PPE family
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
85 LAMC1interactor50.4002.699BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
Laminin_B (PF00052, IPR000034): Laminin B (Domain IV)
Laminin_I (PF06008, IPR009254): Laminin Domain I
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Metal_resist (PF13801, IPR025961): Heavy-metal resistance
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
86 LAMP2protein found in more fusions60.7000.709Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
87 LGALS3BPoncoprotein480.304304.666BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
88 LGALS7suppressor50.6001.346Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
89 LIMA1suppressor100.4896.442LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
90 LMNB2interactor40.8330.049Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
91 LONP1interactor50.6000.851AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_PrkA (PF08298, IPR013153, SM00763): PrkA AAA domain
LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
Lon_C (PF05362, IPR008269): Lon protease (S16) C-terminal proteolytic domain
RuvB_N (PF05496, IPR008824): Holliday junction DNA helicase ruvB N-terminus
AAA_23 (PF13476): AAA domain
92 LRWD1interactor100.5785.053WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
93 MAGED2interactor200.57916.613CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
MAGE (PF01454, IPR002190): MAGE family
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
94 MARK4oncoprotein60.5332.811KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
95 MINOS1interactor41.0000DUF543 (PF04418, IPR007512): Domain of unknown function (DUF543)
96 MMP27interactor100Peptidase_M10 (PF00413, IPR001818): Matrixin
PG_binding_1 (PF01471, IPR002477): Putative peptidoglycan binding domain
Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
97 MRPS34interactor80.6431.751MRP-S34 (PF16053, IPR032053): Mitochondrial 28S ribosomal protein S34
98 MRPS7interactor100.6671.619DUF454 (PF04304, IPR007401): Protein of unknown function (DUF454)
Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
99 MYConcoprotein510.207498.936HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
100 MZT1interactor120.8791.621Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
MOZART1 (PF12554, IPR022214): Mitotic-spindle organizing gamma-tubulin ring associated
101 MZT2Ainteractor140.51620.837MOZART2 (PF12926, IPR024332): Mitotic-spindle organizing gamma-tubulin ring associated
102 MZT2Binteractor130.60316.246MOZART2 (PF12926, IPR024332): Mitotic-spindle organizing gamma-tubulin ring associated
103 NAPGinteractor21.0000SNAP (PF14938): Soluble NSF attachment protein, SNAP
104 NBNsuppressor80.4296.479FHA (PF00498, IPR000253, SM00240): FHA domain
Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1
NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
105 NDE1protein found in more fusions60.4004.125NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
106 NDEL1protein found in more fusions60.4002.709HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
107 NEDD1interactor410.276261.314NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
FliM (PF02154, IPR001689): Flagellar motor switch protein FliM
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
108 NINLinteractor200.24285.919PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
109 NME1suppressor40.6670.100NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
110 NME7interactor130.65415.611DUF1126 (PF06565, IPR010554): Repeat of unknown function (DUF1126)
NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
111 NTRK1oncoprotein990.1642241.836I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
112 OLA1interactor80.6073.043Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933)
113 PARD6Ainteractor60.5333.400PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
114 PARK2suppressor520.260367.783IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
115 PDCD5suppressor21.0000dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
116 PDCD6IPinteractor100.5286.094BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
117 PDCL3interactor61.0000Phosducin (PF02114, IPR024253): Phosducin
UPF0175 (PF03683, IPR005368): Uncharacterised protein family (UPF0175)
118 PFDN2interactor30.6670.333Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
119 PKN3interactor40.5000.976HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
120 PKP1interactor60.6002.100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
121 PLK1suppressor230.33271.128Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
122 PLPPR2interactor21.0000PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
YwiC (PF14256, IPR025576): YwiC-like protein
123 POU5F1oncoprotein330.214193.339Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
124 PPFIA1protein found in more fusions70.4672.698HWE_HK (PF07536, IPR011102, SM00911): HWE histidine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Cluap1 (PF10234, IPR019366): Clusterin-associated protein-1
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
FAM76 (PF16046, IPR032017): FAM76 protein
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
125 PRDX4protein found in more fusions31.0000AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
126 PRICKLE3interactor31.0000LIM (PF00412, IPR001781, SM00132): LIM domain
PET (PF06297, IPR010442): PET Domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
127 PRKACAinteractor60.7332.667Pkinase (PF00069, IPR000719): Protein kinase domain
128 PRPF3protein found in more fusions80.4291.926DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115)
PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3)
PWI (PF01480, IPR002483, SM00311): PWI domain
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
129 PRSS21interactor31.0000Trypsin (PF00089, IPR001254, SM00020): Trypsin
130 PSMD8interactor60.6671.792CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
131 PSME1interactor50.8330.182PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)
132 PTPN23suppressor50.7000.695BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
SOGA (PF11365, IPR027881): Protein SOGA
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
133 PXNoncoprotein40.5001.467LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
134 RAB8Boncoprotein60.4673.562Ras (PF00071, IPR001806, SM00173): Ras family
135 RAD51interactor80.5713.720Rad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
136 RASSF1suppressor80.7141.335RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
137 RAVER1interactor100.4443.162RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
138 RICTORinteractor150.30537.840RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term
RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site
RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain
RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5
139 RPL10Ainteractor490.73563.250Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
140 RPL10Linteractor340.9551.489Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
Cytochrome_P460 (PF16694, IPR032033): Cytochrome P460
141 RPL13interactor480.72053.192Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
142 RPL13Ainteractor390.8957.290Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
143 RPL14interactor470.80419.604KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
144 RPL17interactor430.78827.003Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
145 RPL18Ainteractor430.86212.259Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
146 RPL21interactor470.80425.361Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
147 RPL22oncoprotein470.75037.719Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
148 RPL23interactor510.68475.973Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
149 RPL24protein found in more fusions490.732109.765MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
150 RPL26oncoprotein310.83913.406TP2 (PF01254, IPR000678): Nuclear transition protein 2
Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
151 RPL26L1interactor230.8932.537Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
152 RPL3interactor520.71755.016Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
153 RPL31interactor460.76444.620Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
154 RPL5suppressor530.70973.323Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
155 RPL6interactor540.692114.187Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
156 RPL7interactor500.75332.828Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
157 RPLP0interactor520.73743.317Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
158 RPLP2protein found in more fusions460.75735.848Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
159 RPN1oncoprotein150.6196.688Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
160 RPS10interactor470.723118.367S10_plectin (PF03501, IPR005326): Plectin/S10 domain
161 RPS11interactor460.80422.935Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
162 RPS13interactor480.79534.888Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
163 RPS14interactor500.75631.217Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
164 RPS15interactor400.86711.800Ribosomal_S19 (PF00203, IPR002222): Ribosomal protein S19
Prok_Ub (PF14454, IPR032866): Prokaryotic Ubiquitin
165 RPS15Ainteractor480.73249.154Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
166 RPS16interactor540.70450.180Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
167 RPS17interactor320.9113.170Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
168 RPS18interactor470.79223.568Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
169 RPS2interactor530.71287.885Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
170 RPS23interactor440.85016.389Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
171 RPS25interactor490.73940.872Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
172 RPS3interactor620.565181.222KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
173 RPS3Ainteractor520.73247.605Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
174 RPS4Xinteractor570.66384.314KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
175 RPS6interactor520.72946.532Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
176 RPS8interactor550.673111.817Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
177 RPS9interactor480.77530.061Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
178 SAMHD1protein found in more fusions110.4675.409HD (PF01966, IPR006674): HD domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
179 SCAF11interactor130.7187.841DUF566 (PF04484, IPR007573): Family of unknown function (DUF566)
Phage_XkdX (PF09693, IPR010022): Phage uncharacterised protein (Phage_XkdX)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
180 SDF4interactor80.3575.277Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
181 SGPP1interactor100DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
182 SKP1oncoprotein120.5306.715Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
183 SMG1interactor60.6000.800Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
SMG1 (PF15785, IPR031559): Serine/threonine-protein kinase smg-1
184 SNCAinteractor200.39849.367Synuclein (PF01387, IPR001058): Synuclein
185 SNW1protein found in more fusions430.294244.709SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
186 SOCS1suppressor31.0000SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
187 SOX2oncoprotein150.30827.099HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
188 SPATC1interactor21.0000Speriolin_N (PF15058, IPR029385): Speriolin N terminus
Speriolin_C (PF15059, IPR029384): Speriolin C-terminus
189 SPINT2suppressor60.5334.681Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
190 SPTBN1suppressor100.4894.921CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
191 SQRDLinteractor30.6670.250Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
192 STIP1interactor140.6705.020TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
193 SUPT6Hinteractor80.3575.630Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
Tex_N (PF09371, IPR018974): Tex-like protein N-terminal domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SH2_2 (PF14633, IPR000980): SH2 domain
HHH_7 (PF14635, IPR032706): Helix-hairpin-helix motif
YqgF (PF14639, IPR028231): Holliday-junction resolvase-like of SPT6
HTH_44 (PF14641, IPR028088): Helix-turn-helix DNA-binding domain of SPT6
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
DLD (PF14878, IPR027999): Death-like domain of SPT6
194 SYKsuppressor80.5714.006Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
195 TCP1interactor290.56432.690Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
196 TFB2Minteractor40.5000.306RrnaAD (PF00398, IPR001737, SM00650): Ribosomal RNA adenine dimethylase
197 TIMM13interactor60.3334.271zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
198 TIMM50interactor70.5713.399NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
199 TMPOinteractor90.4178.625LEM (PF03020, IPR003887, SM00540): LEM domain
Thymopoietin (PF08198, IPR013146): Thymopoietin protein
LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
200 TMUB1interactor31.0000DUF347 (PF03988, IPR007136): Repeat of Unknown Function (DUF347)
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF4227 (PF14004, IPR025321): Protein of unknown function (DUF4227)
201 TP53suppressor920.2641310.067DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
202 TUBA1Aoncoprotein360.297203.320Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
203 TUBA1Cinteractor410.345187.329Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
204 TUBA4Ainteractor250.47734.401Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
205 TUBBinteractor480.334271.964Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
206 TUBB1interactor80.3573.608Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
207 TUBB4Binteractor330.40379.924Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
208 TUBGCP2interactor400.306241.689Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
209 TUBGCP3interactor530.292433.202Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
210 TUBGCP4interactor360.337154.592Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
211 TUBGCP5interactor130.7824.352Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
GCP5-Mod21 (PF14609, IPR032797): gamma-Tubulin ring complex non-core subunit mod21
212 TUBGCP6interactor130.7056.745Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
213 UBBinteractor120.3188.455ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
214 UBR5protein found in more fusions140.41010.010CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SDA1 (PF05285, IPR007949): SDA1
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
215 UNC5Bsuppressor21.0000Death (PF00531, IPR000488, SM00005): Death domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
Ig_3 (PF13927): Immunoglobulin domain
UPA (PF17217): UPA domain
216 WIZinteractor60.4673.500AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog)
C1_2 (PF03107, IPR004146): C1 domain
Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST
zf-C2H2_4 (PF13894): C2H2-type zinc finger
217 XPO1interactor610.272644.623CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
218 XRN1interactor110.45512.264XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
219 YWHAHprotein found in more fusions130.34821.09314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
220 YWHAZprotein found in more fusions220.29076.54614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
221 ZFAND3interactor100FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 HSPA7interactorNA
2 RPL27AP6interactorNA
3 RPL7AP27interactorNA
4 TUBG1parental proteinTubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain

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