1 |
CD368741 | chimera | 238 | 0.148 | 16031.789 | CDC45 (PF02724, IPR003874): CDC45-like protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
2 |
ACIN1 | interactor | 36 | 0.492 | 47.132 | Calc_CGRP_IAPP (PF00214, IPR021116): Calcitonin / CGRP / IAPP family CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family FAM27 (PF15832, IPR031672): FAM27 D and E protein family DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) RSB_motif (PF16294, IPR032552): RNSP1-SAP18 binding (RSB) motif SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal |
3 |
AES | protein found in more fusions | 10 | 0.278 | 11.357 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain |
4 |
AHNAK | suppressor | 21 | 0.489 | 28.260 | DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945) ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993) DUF4097 (PF13349, IPR025164): Putative adhesin Ntox37 (PF15535, IPR029108): Bacterial toxin 37 |
5 |
ALYREF | interactor | 42 | 0.483 | 78.697 | FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
6 |
ANP32A | suppressor | 10 | 0.444 | 9.660 | SDA1 (PF05285, IPR007949): SDA1 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_9 (PF14580): Leucine-rich repeat |
7 |
APBB1 | interactor | 25 | 0.319 | 38.908 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID) |
8 |
ARPC1B | interactor | 5 | 0.700 | 1.333 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
9 |
ATXN1 | protein found in more fusions | 12 | 0.309 | 24.294 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) Spt20 (PF12090, IPR021950): Spt20 family ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term |
10 |
BARD1 | suppressor | 43 | 0.300 | 108.889 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
11 |
CALCOCO2 | interactor | 6 | 0.600 | 1.667 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding zf-C2H2_4 (PF13894): C2H2-type zinc finger |
12 |
CALM1 | interactor | 21 | 0.462 | 18.471 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
13 |
CALR | oncoprotein | 26 | 0.433 | 48.842 | Calreticulin (PF00262, IPR001580): Calreticulin family DDHD (PF02862, IPR004177, SM01127): DDHD domain |
14 |
CAND1 | interactor | 115 | 0.296 | 770.341 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
15 |
CANX | interactor | 26 | 0.471 | 32.368 | Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
16 |
CCAR1 | suppressor | 12 | 0.424 | 6.999 | Cucumo_2B (PF03263, IPR004946): Cucumovirus protein 2B DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) IncA (PF04156, IPR007285): IncA protein Presenilin (PF01080, IPR001108): Presenilin SAP (PF02037, IPR003034, SM00513): SAP domain FimP (PF09766, IPR019163): Fms-interacting protein DBC1 (PF14443, IPR025954, SM01122): DBC1 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) S1-like (PF14444, IPR025223): S1-like DUF4481 (PF14800, IPR028054): Domain of unknown function (DUF4481) FAM176 (PF14851): FAM176 family |
17 |
CDC37 | protein found in more fusions | 22 | 0.443 | 16.334 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
18 |
CDC5L | interactor | 97 | 0.317 | 730.453 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
19 |
CHD8 | oncoprotein | 6 | 0.667 | 0.753 | BUD22 (PF09073, IPR015158): BUD22 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Myb_DNA-bind_7 (PF15963): Myb DNA-binding like |
20 |
CHERP | interactor | 18 | 0.536 | 11.305 | CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. G-patch (PF01585, IPR000467, SM00443): G-patch domain HpaP (PF09483, IPR013390): Type III secretion protein (HpaP) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TP2 (PF01254, IPR000678): Nuclear transition protein 2 Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain Surp (PF01805, IPR000061, SM00648): Surp module |
21 |
CHTOP | interactor | 8 | 0.643 | 0.586 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) Lamprin (PF06403, IPR009437): Lamprin FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
22 |
COPS5 | protein found in more fusions | 109 | 0.281 | 751.207 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
23 |
CORO1A | oncoprotein | 2 | 1.000 | 0 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
24 |
CPSF6 | interactor | 26 | 0.495 | 20.359 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
25 |
CUL1 | suppressor | 96 | 0.328 | 540.861 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
26 |
CUL3 | protein found in more fusions | 136 | 0.251 | 1423.184 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
27 |
CUL5 | suppressor | 73 | 0.339 | 251.423 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
28 |
CUL7 | protein found in more fusions | 131 | 0.204 | 1483.085 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
29 |
DACH1 | suppressor | 3 | 1.000 | 0 | DUF508 (PF04370, IPR007465): Domain of unknown function (DUF508) Pap_E4 (PF02711, IPR003861): E4 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family Macoilin (PF09726, IPR019130): Transmembrane protein SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
30 |
DARS | interactor | 12 | 0.576 | 4.299 | tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain |
31 |
DDX17 | protein found in more fusions | 51 | 0.473 | 100.358 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
32 |
DDX21 | interactor | 38 | 0.448 | 57.650 | CRT10 (PF08728, IPR014839): CRT10 DEAD (PF00270, IPR011545): DEAD/DEAH box helicase GUCT (PF08152, IPR012562): GUCT (NUC152) domain Sulfatase (PF00884, IPR000917): Sulfatase MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
33 |
DDX39B | interactor | 19 | 0.515 | 10.935 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
34 |
DDX3X | suppressor | 40 | 0.431 | 62.852 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
35 |
DDX5 | oncoprotein | 64 | 0.442 | 166.945 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
36 |
DHX15 | interactor | 60 | 0.418 | 238.657 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
37 |
DHX9 | oncoprotein | 68 | 0.428 | 225.012 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
38 |
DPPA2 | interactor | 2 | 0 | 0 | SAP (PF02037, IPR003034, SM00513): SAP domain DCR (PF14047, IPR025891): Dppa2/4 conserved region Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates |
39 |
DYNC1H1 | interactor | 25 | 0.423 | 36.096 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
40 |
EED | suppressor | 105 | 0.246 | 773.702 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
41 |
EEF1A1 | suppressor | 56 | 0.383 | 163.465 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
42 |
EEF2 | interactor | 38 | 0.506 | 50.194 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
43 |
EFTUD2 | interactor | 50 | 0.486 | 94.668 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus |
44 |
EIF3A | oncoprotein | 14 | 0.538 | 5.139 | DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003) Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region PCI (PF01399, IPR000717, SM00088): PCI domain AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
45 |
EIF4A1 | interactor | 23 | 0.577 | 25.081 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
46 |
EIF4A3 | interactor | 87 | 0.355 | 485.710 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
47 |
EIF5A | interactor | 12 | 0.591 | 4.787 | EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold |
48 |
ELAVL1 | oncoprotein | 88 | 0.268 | 804.785 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
49 |
EPRS | interactor | 22 | 0.476 | 25.495 | GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
50 |
ESR1 | suppressor | 97 | 0.232 | 832.426 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
51 |
EWSR1 | oncoprotein | 76 | 0.296 | 550.924 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
52 |
EZH2 | suppressor | 55 | 0.279 | 157.142 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
53 |
EZR | protein found in more fusions | 18 | 0.412 | 33.042 | DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
54 |
FBL | interactor | 30 | 0.543 | 18.308 | Fibrillarin (PF01269, IPR000692): Fibrillarin |
55 |
FUBP1 | oncoprotein | 18 | 0.542 | 10.451 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
56 |
GANAB | suppressor | 13 | 0.603 | 12.836 | Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31 Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like DUF5110 (PF17137): Domain of unknown function (DUF5110) |
57 |
GIGYF2 | interactor | 14 | 0.560 | 4.829 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GYF (PF02213, IPR003169, SM00444): GYF domain Macoilin (PF09726, IPR019130): Transmembrane protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 DUF3801 (PF12687, IPR024234): Protein of unknown function (DUF3801) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_23 (PF13476): AAA domain ARGLU (PF15346): Arginine and glutamate-rich 1 PRTase_3 (PF15610, IPR028944): PRTase ComF-like Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
58 |
GLIS2 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
59 |
GNAI2 | oncoprotein | 8 | 0.571 | 2.211 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
60 |
H2AFJ | interactor | 3 | 1.000 | 0 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
61 |
HDGF | interactor | 33 | 0.366 | 45.255 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
62 |
HMGB1 | oncoprotein | 9 | 0.472 | 8.147 | HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
63 |
HMGB2 | protein found in more fusions | 5 | 0.700 | 0.855 | HMG_box_2 (PF09011, IPR009071): HMG-box domain NOA36 (PF06524, IPR010531): NOA36 protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
64 |
HNRNPA0 | interactor | 41 | 0.644 | 32.648 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
65 |
HNRNPA1 | interactor | 98 | 0.364 | 473.925 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
66 |
HNRNPA2B1 | oncoprotein | 43 | 0.548 | 59.432 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
67 |
HNRNPA3 | oncoprotein | 45 | 0.541 | 57.280 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
68 |
HNRNPAB | interactor | 33 | 0.576 | 36.704 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462) |
69 |
HNRNPC | protein found in more fusions | 51 | 0.496 | 92.174 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
70 |
HNRNPD | oncoprotein | 55 | 0.461 | 126.197 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
71 |
HNRNPDL | interactor | 42 | 0.569 | 48.321 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
72 |
HNRNPF | interactor | 44 | 0.566 | 68.494 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
73 |
HNRNPH1 | oncoprotein | 52 | 0.534 | 85.568 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
74 |
HNRNPK | oncoprotein | 81 | 0.396 | 394.367 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
75 |
HNRNPL | protein found in more fusions | 45 | 0.557 | 63.707 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
76 |
HNRNPM | interactor | 67 | 0.422 | 191.083 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
77 |
HNRNPR | interactor | 69 | 0.470 | 199.564 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
78 |
HNRNPU | interactor | 93 | 0.354 | 493.644 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
79 |
HSP90AA1 | oncoprotein | 49 | 0.399 | 163.897 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
80 |
HSP90AB1 | oncoprotein | 39 | 0.448 | 84.293 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
81 |
HSP90B1 | suppressor | 28 | 0.487 | 30.503 | CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region |
82 |
HSPA1A | interactor | 30 | 0.494 | 57.436 | HSP70 (PF00012, IPR013126): Hsp70 protein |
83 |
HSPA5 | oncoprotein | 62 | 0.398 | 246.364 | HSP70 (PF00012, IPR013126): Hsp70 protein |
84 |
HSPA8 | oncoprotein | 38 | 0.442 | 117.061 | HSP70 (PF00012, IPR013126): Hsp70 protein |
85 |
HSPA9 | oncoprotein | 26 | 0.566 | 19.047 | HSP70 (PF00012, IPR013126): Hsp70 protein |
86 |
HUWE1 | oncoprotein | 69 | 0.232 | 424.661 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
87 |
IFI16 | suppressor | 20 | 0.216 | 51.491 | HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
88 |
IK | interactor | 28 | 0.521 | 24.785 | Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
89 |
IL7R | interactor | 42 | 0.289 | 82.990 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
90 |
ILF2 | interactor | 56 | 0.484 | 93.661 | DZF (PF07528, IPR006561, SM00572): DZF domain |
91 |
ILF3 | oncoprotein | 60 | 0.439 | 167.390 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
92 |
IQGAP1 | interactor | 20 | 0.521 | 22.922 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
93 |
KHDRBS1 | protein found in more fusions | 34 | 0.562 | 34.416 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
94 |
KHDRBS3 | interactor | 9 | 0.679 | 3.093 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
95 |
KHSRP | interactor | 23 | 0.518 | 9.981 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain |
96 |
KIAA1429 | interactor | 9 | 0.583 | 4.320 | Mpp10 (PF04006, IPR007151): Mpp10 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus VIR_N (PF15912, IPR031801): Virilizer, N-terminal |
97 |
KIFC1 | interactor | 2 | 1.000 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 IncA (PF04156, IPR007285): IncA protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit Microtub_bd (PF16796, IPR031852): Microtubule binding |
98 |
KPNB1 | protein found in more fusions | 25 | 0.428 | 53.056 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat |
99 |
LAMB3 | interactor | 3 | 0.667 | 0.200 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Laminin_II (PF06009, IPR010307): Laminin Domain II Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI) Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase SOAR (PF16533, IPR032393): STIM1 Orai1-activating region |
100 |
LARP1 | interactor | 26 | 0.529 | 21.712 | La (PF05383, IPR006630, SM00715): La domain Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
101 |
LASP1 | oncoprotein | 6 | 0.400 | 7.500 | LIM (PF00412, IPR001781, SM00132): LIM domain Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat SH3_9 (PF14604, IPR001452): Variant SH3 domain |
102 |
LCP1 | oncoprotein | 4 | 0.833 | 0.222 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
103 |
LGALS1 | interactor | 10 | 0.422 | 15.756 | Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin |
104 |
LRRFIP1 | oncoprotein | 8 | 0.536 | 3.993 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 LRRFIP (PF09738, IPR019139): LRRFIP family RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region Coilin_N (PF15862, IPR031722): Coilin N-terminus |
105 |
LUC7L2 | protein found in more fusions | 46 | 0.453 | 76.368 | LUC7 (PF03194, IPR004882): LUC7 N_terminus Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain |
106 |
MAPRE1 | oncoprotein | 14 | 0.436 | 12.919 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
107 |
MATR3 | interactor | 53 | 0.481 | 109.685 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
108 |
MCM2 | oncoprotein | 94 | 0.219 | 855.963 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
109 |
MDH2 | protein found in more fusions | 9 | 0.571 | 2.573 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
110 |
MDM2 | oncoprotein | 52 | 0.291 | 250.325 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
111 |
MSN | oncoprotein | 18 | 0.419 | 30.871 | DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
112 |
MVP | oncoprotein | 12 | 0.400 | 12.239 | Vault (PF01505, IPR002499): Major Vault Protein repeat DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543) MVP_shoulder (PF11978, IPR021870): Shoulder domain |
113 |
NCBP1 | interactor | 30 | 0.409 | 53.583 | MIF4G (PF02854, IPR003890, SM00543): MIF4G domain MIF4G_like (PF09088, IPR015172): MIF4G like MIF4G_like_2 (PF09090, IPR015174): MIF4G like SlyX (PF04102, IPR007236): SlyX |
114 |
NCL | protein found in more fusions | 45 | 0.463 | 74.457 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
115 |
NONO | oncoprotein | 35 | 0.487 | 43.398 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
116 |
NOP56 | interactor | 32 | 0.558 | 24.086 | Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal |
117 |
NPM1 | suppressor | 65 | 0.347 | 315.809 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
118 |
NTRK1 | oncoprotein | 174 | 0.180 | 3835.457 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
119 |
NUMA1 | oncoprotein | 20 | 0.400 | 18.159 | Colicin (PF01024, IPR000293): Colicin pore forming domain Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
120 |
OBSL1 | interactor | 131 | 0.207 | 1422.024 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
121 |
P4HB | interactor | 30 | 0.424 | 48.815 | Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
122 |
PA2G4 | interactor | 16 | 0.667 | 4.043 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein |
123 |
PABPC1 | oncoprotein | 55 | 0.412 | 143.114 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
124 |
PABPC4 | interactor | 36 | 0.471 | 50.991 | ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family |
125 |
PABPN1 | interactor | 15 | 0.619 | 3.311 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Shadoo (PF14999, IPR029238): Shadow of prion protein, neuroprotective |
126 |
PAICS | interactor | 9 | 0.750 | 0.634 | AIRC (PF00731, IPR000031, SM01001): AIR carboxylase SAICAR_synt (PF01259, IPR028923): SAICAR synthetase |
127 |
PCBP1 | oncoprotein | 43 | 0.395 | 126.543 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
128 |
PCNA | oncoprotein | 26 | 0.410 | 44.778 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
129 |
PDIA3 | interactor | 20 | 0.437 | 37.332 | Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
130 |
PDIA6 | interactor | 16 | 0.625 | 3.628 | FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
131 |
PHB2 | interactor | 17 | 0.493 | 15.986 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
132 |
PHGDH | interactor | 30 | 0.480 | 28.362 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
133 |
PIN1 | suppressor | 25 | 0.417 | 27.863 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
134 |
PKM | oncoprotein | 31 | 0.484 | 47.744 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
135 |
PLRG1 | interactor | 19 | 0.667 | 8.371 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
136 |
PNN | suppressor | 23 | 0.593 | 11.843 | Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) |
137 |
POC1A | interactor | 3 | 0.667 | 1.000 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
138 |
POLDIP3 | interactor | 11 | 0.473 | 3.812 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
139 |
POLR2A | protein found in more fusions | 28 | 0.422 | 45.997 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
140 |
PPIE | interactor | 5 | 0.800 | 0.083 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
141 |
PRPF3 | protein found in more fusions | 32 | 0.548 | 25.922 | DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3) PWI (PF01480, IPR002483, SM00311): PWI domain TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) |
142 |
PRPF40A | protein found in more fusions | 47 | 0.504 | 71.359 | FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
143 |
PRPF6 | protein found in more fusions | 34 | 0.559 | 31.065 | PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
144 |
PRPF8 | oncoprotein | 55 | 0.456 | 122.670 | PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain PROCN (PF08083, IPR012592): PROCN (NUC071) domain PROCT (PF08084, IPR012984): PROCT (NUC072) domain RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8 JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core |
145 |
PSMA7 | protein found in more fusions | 14 | 0.526 | 7.734 | Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
146 |
PSMD2 | oncoprotein | 15 | 0.514 | 7.240 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
147 |
PSPC1 | interactor | 10 | 0.489 | 2.350 | FUSC (PF04632, IPR006726): Fusaric acid resistance protein family NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zot (PF05707, IPR008900): Zonular occludens toxin (Zot) |
148 |
PTBP1 | oncoprotein | 56 | 0.412 | 189.859 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
149 |
PTPRC | suppressor | 3 | 0.667 | 0.667 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase PTP_N (PF12453, IPR024739): Protein tyrosine phosphatase N terminal CD45 (PF12567, IPR016335): Leukocyte receptor CD45 SCIMP (PF15050, IPR028181): SCIMP protein |
150 |
PUF60 | protein found in more fusions | 43 | 0.467 | 73.090 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
151 |
QKI | protein found in more fusions | 16 | 0.486 | 21.923 | KH_1 (PF00013, IPR004088, SM00322): KH domain STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking |
152 |
RAB7A | suppressor | 13 | 0.500 | 6.837 | Ras (PF00071, IPR001806, SM00173): Ras family |
153 |
RAC2 | oncoprotein | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
154 |
RACK1 | suppressor | 32 | 0.413 | 60.927 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
155 |
RALY | interactor | 34 | 0.613 | 24.648 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
156 |
RAN | oncoprotein | 18 | 0.510 | 8.223 | Ras (PF00071, IPR001806, SM00173): Ras family |
157 |
RBFOX2 | protein found in more fusions | 18 | 0.507 | 27.631 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal |
158 |
RBM10 | interactor | 23 | 0.489 | 36.514 | G-patch (PF01585, IPR000467, SM00443): G-patch domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site zf-C2H2_4 (PF13894): C2H2-type zinc finger DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337) FAM176 (PF14851): FAM176 family |
159 |
RBM39 | oncoprotein | 56 | 0.424 | 168.172 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
160 |
RBM4 | suppressor | 27 | 0.607 | 19.038 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC (PF00098, IPR001878): Zinc knuckle CompInhib_SCIN (PF11546, IPR021612): Staphylococcal complement inhibitor SCIN |
161 |
RBM5 | suppressor | 9 | 0.694 | 0.687 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) G-patch (PF01585, IPR000467, SM00443): G-patch domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
162 |
RBMX | suppressor | 47 | 0.514 | 75.666 | RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
163 |
RHOA | suppressor | 8 | 0.429 | 4.307 | Ras (PF00071, IPR001806, SM00173): Ras family |
164 |
RNF2 | interactor | 92 | 0.227 | 787.012 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
165 |
RNPS1 | interactor | 54 | 0.437 | 106.917 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) Macoilin (PF09726, IPR019130): Transmembrane protein |
166 |
RPL6 | interactor | 50 | 0.456 | 94.786 | Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain |
167 |
RPN1 | oncoprotein | 23 | 0.522 | 17.473 | Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain |
168 |
RPS24 | interactor | 34 | 0.510 | 37.189 | Fascin (PF06268, IPR022768): Fascin domain Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
169 |
RRP7A | interactor | 12 | 0.485 | 3.545 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 (PF12923, IPR024326): Ribosomal RNA-processing protein 7 (RRP7) |
170 |
S100A6 | interactor | 3 | 1.000 | 0 | S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
171 |
S100A9 | oncoprotein | 29 | 0.476 | 22.860 | S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
172 |
SAFB | suppressor | 27 | 0.499 | 27.777 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
173 |
SARNP | oncoprotein | 4 | 0.833 | 0.069 | SAP (PF02037, IPR003034, SM00513): SAP domain HTH_Tnp_IS630 (PF01710, IPR002622): Transposase Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A |
174 |
SEPT2 | oncoprotein | 26 | 0.471 | 24.467 | FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Septin (PF00735, IPR000038): Septin |
175 |
SEPT7 | interactor | 22 | 0.545 | 14.324 | Fez1 (PF06818): Fez1 Septin (PF00735, IPR000038): Septin |
176 |
SEPT9 | oncoprotein | 12 | 0.697 | 2.517 | Septin (PF00735, IPR000038): Septin DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
177 |
SERBP1 | protein found in more fusions | 20 | 0.608 | 7.223 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
178 |
SF1 | protein found in more fusions | 25 | 0.507 | 28.581 | UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain |
179 |
SF3A1 | interactor | 52 | 0.500 | 93.544 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
180 |
SF3A2 | interactor | 68 | 0.337 | 315.212 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
181 |
SF3B1 | oncoprotein | 56 | 0.494 | 98.316 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
182 |
SF3B2 | interactor | 35 | 0.519 | 40.456 | DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382) PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region PSP (PF04046, IPR006568, SM00581): PSP SAP (PF02037, IPR003034, SM00513): SAP domain Usp (PF00582, IPR006016): Universal stress protein family Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
183 |
SF3B3 | interactor | 59 | 0.474 | 133.020 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
184 |
SF3B6 | interactor | 33 | 0.479 | 39.120 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
185 |
SFPQ | oncoprotein | 50 | 0.449 | 87.754 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
186 |
SH3RF2 | interactor | 3 | 0.667 | 0.125 | SH3_2 (PF07653, IPR011511): Variant SH3 domain TUDOR (PF00567, IPR002999, SM00333): Tudor domain UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547 SH3_1 (PF00018, IPR001452, SM00326): SH3 domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger SH3_9 (PF14604, IPR001452): Variant SH3 domain |
187 |
SIRT7 | interactor | 83 | 0.166 | 894.205 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
188 |
SLC25A5 | interactor | 26 | 0.511 | 24.829 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
189 |
SLC9A3R1 | suppressor | 7 | 0.600 | 1.456 | EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
190 |
SLIRP | interactor | 8 | 0.429 | 4.962 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
191 |
SMARCAD1 | interactor | 29 | 0.438 | 36.498 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
192 |
SND1 | interactor | 25 | 0.603 | 10.962 | TUDOR (PF00567, IPR002999, SM00333): Tudor domain SNase (PF00565, IPR016071, SM00318): Staphylococcal nuclease homologue |
193 |
SNRNP200 | protein found in more fusions | 51 | 0.501 | 97.198 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
194 |
SNRNP70 | interactor | 47 | 0.503 | 71.463 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal |
195 |
SNRPA | interactor | 36 | 0.509 | 32.058 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
196 |
SNRPD1 | interactor | 47 | 0.516 | 59.319 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) LSM (PF01423, IPR001163): LSM domain |
197 |
SNW1 | protein found in more fusions | 100 | 0.300 | 717.593 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
198 |
SON | interactor | 41 | 0.420 | 73.937 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region G-patch (PF01585, IPR000467, SM00443): G-patch domain tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1 GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer RSRP (PF17069): Arginine/Serine-Rich protein 1 |
199 |
SPTAN1 | oncoprotein | 26 | 0.542 | 26.224 | EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Tetrabrachion (PF11401, IPR021535): Tetrabrachion EF-hand_7 (PF13499, IPR011992): EF-hand domain pair E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
200 |
SRPK1 | interactor | 45 | 0.455 | 88.743 | FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) Pkinase (PF00069, IPR000719): Protein kinase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
201 |
SRPK2 | oncoprotein | 63 | 0.326 | 313.596 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
202 |
SRRM1 | interactor | 53 | 0.429 | 122.649 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
203 |
SRRM2 | interactor | 79 | 0.408 | 321.028 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
204 |
SRSF1 | protein found in more fusions | 67 | 0.489 | 155.525 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
205 |
SRSF10 | interactor | 27 | 0.436 | 36.436 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
206 |
SRSF11 | interactor | 37 | 0.455 | 50.583 | Rtf2 (PF04641, IPR027799): Rtf2 RING-finger RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
207 |
SRSF2 | oncoprotein | 38 | 0.492 | 44.399 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
208 |
SRSF3 | oncoprotein | 56 | 0.444 | 105.876 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
209 |
SRSF4 | interactor | 20 | 0.637 | 7.410 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
210 |
SRSF5 | interactor | 51 | 0.445 | 96.331 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
211 |
SRSF6 | oncoprotein | 33 | 0.576 | 23.754 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Tox-HNH-EHHH (PF15657, IPR028048): HNH/Endo VII superfamily nuclease toxins |
212 |
SRSF7 | interactor | 55 | 0.475 | 91.750 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-CCHC (PF00098, IPR001878): Zinc knuckle |
213 |
SRSF9 | interactor | 35 | 0.529 | 34.261 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
214 |
STIP1 | interactor | 20 | 0.495 | 18.903 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP |
215 |
SUGP1 | interactor | 5 | 0.700 | 1.952 | G-patch (PF01585, IPR000467, SM00443): G-patch domain Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor MAS20 (PF02064, IPR002056): MAS20 protein import receptor NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region OrfB_IS605 (PF01385, IPR001959): Probable transposase RtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB Surp (PF01805, IPR000061, SM00648): Surp module G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site |
216 |
SUZ12 | suppressor | 80 | 0.224 | 522.642 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
217 |
SYNCRIP | interactor | 57 | 0.473 | 135.776 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
218 |
TARDBP | interactor | 76 | 0.349 | 281.695 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
219 |
TCERG1 | interactor | 30 | 0.379 | 54.329 | FF (PF01846, IPR002713, SM00441): FF domain WW (PF00397, IPR001202, SM00456): WW domain Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO FAM150 (PF15129, IPR029364): FAM150 family |
220 |
THAP1 | interactor | 6 | 0.500 | 3.033 | THAP (PF05485, IPR006612, SM00980): THAP domain Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2 Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 |
221 |
THOC6 | interactor | 15 | 0.476 | 8.119 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
222 |
THRAP3 | oncoprotein | 37 | 0.423 | 52.419 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family |
223 |
TLN1 | interactor | 12 | 0.667 | 3.301 | DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site CoatB (PF10389, IPR008020): Bacteriophage coat protein B LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM |
224 |
TOP1 | oncoprotein | 56 | 0.453 | 154.880 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
225 |
TPR | oncoprotein | 29 | 0.399 | 50.021 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
226 |
TRA2A | interactor | 46 | 0.460 | 75.716 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
227 |
TRA2B | interactor | 38 | 0.545 | 41.857 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
228 |
TRIM28 | protein found in more fusions | 20 | 0.491 | 5.346 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
229 |
TUBB | interactor | 30 | 0.547 | 31.065 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
230 |
TUFM | interactor | 22 | 0.506 | 13.507 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
231 |
U2AF1 | oncoprotein | 58 | 0.404 | 169.879 | DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509) KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
232 |
UPF1 | interactor | 31 | 0.523 | 32.477 | UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain) AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain |
233 |
VCP | protein found in more fusions | 54 | 0.347 | 259.507 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
234 |
WARS | interactor | 5 | 0.700 | 0.695 | tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
235 |
WDR1 | interactor | 10 | 0.444 | 7.585 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
236 |
XRCC6 | oncoprotein | 33 | 0.482 | 41.082 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
237 |
YBX1 | oncoprotein | 48 | 0.425 | 105.921 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
238 |
ZC3H13 | interactor | 8 | 0.536 | 2.908 | FGF-BP1 (PF06473, IPR010510): FGF binding protein 1 (FGF-BP1) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) PET117 (PF15786, IPR031568): PET assembly of cytochrome c oxidase, mitochondrial |
239 |
ZYX | suppressor | 7 | 0.524 | 6.685 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) LIM (PF00412, IPR001781, SM00132): LIM domain DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757) |