Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: CD050400 is the fusion of parental proteins PAK4, RPS12 (from a repository: Mon Oct 14 16:57:27 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)115
The number (and %) of the onco-proteins29 (25.22 %)
The number (and %) of the tumor suppressors11 (9.57 %)
Total number of binary PPIs (saturation %)2952 (45.03 %)
The number (and %) of affected PPIs114 (3.86 %)
The number of possible different fusions21
PPI diameter2
PPI radius1
The average degree of PPI50.939
Assortativity coefficient0.0401
The network average Clustering coefficient0.733
The number (and %) of a zero Clustering coefficients3 (2.61 %)
The number (and %) of a zero Betweenness Centrality6 (5.22 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: PAK4,RPS12 All fusions
: CD050400;
Proteins found in more fusions NPM1 (see 1 fusions); CUL1 (see 3 fusions); RPS5/RPL14 (see 1 fusions); HNRNPU/RPL24 (see 1 fusions); SNW1 (see 1 fusions); APP (see 4 fusions); RPS24/RPS23 (see 1 fusions); RPS24/RPS27 (see 1 fusions); RPL27/RPS6 (see 1 fusions); HNRNPD (see 1 fusions); BAG3 (see 4 fusions); RPL38/RPL3 (see 1 fusions); RANBP9 (see 2 fusions); RPS19/RPS14 (see 1 fusions); CUL3 (see 1 fusions); RACK1/FN1 (see 1 fusions); UBC (see 1 fusions); MCM2 (see 1 fusions); RACK1 (see 3 fusions); FN1/RPL6 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CD050400chimera1140.4372459.176Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
2 ABCE1interactor190.49721.202ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 APPprotein found in more fusions290.55854.701APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 BAG3oncoprotein80.4764.475BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
5 CBX8interactor140.8590.799Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RBR (PF17208): RNA binding Region
CBX7_C (PF17218): CBX family C-terminal motif
6 CD4suppressor130.6216.056ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
7 CDK2suppressor580.674182.445Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
8 CEP250interactor430.9632.877ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
9 CUL1suppressor670.773128.957Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
10 CUL3protein found in more fusions710.666241.483Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
11 DDX6oncoprotein60.6670.227DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
12 DYNC1LI1interactor60.4672.815DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC)
13 EIF3Aoncoprotein170.6405.285DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
14 EIF3CLinteractor190.7784.521eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus
PCI (PF01399, IPR000717, SM00088): PCI domain
15 EIF3Dinteractor200.56813.292eIF-3_zeta (PF05091, IPR007783): Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
16 EIF3Eoncoprotein240.59431.376eIF3_N (PF09440, IPR019010): eIF3 subunit 6 N terminal domain
PCI (PF01399, IPR000717, SM00088): PCI domain
HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain
SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
17 ESR1suppressor540.80049.577Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
18 FAUinteractor320.8893.565Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
19 FN1oncoprotein670.710137.246fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
20 HECW2interactor50.8330.286C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
21 HIST1H1Ainteractor110.8550.687Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
22 HIST1H3Einteractor210.72910.871Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
23 HNRNPDoncoprotein160.4579.263CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
24 HNRNPUprotein found in more fusions730.735127.714CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
25 IKBKGinteractor90.3579.162CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
26 ITGB5interactor100EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
27 LARP1interactor230.7319.395La (PF05383, IPR006630, SM00715): La domain
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
28 LATS2suppressor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
29 MCM2oncoprotein670.669132.777AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
30 NAA20interactor100Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
31 NDUFS6interactor100Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
zf-CHCC (PF10276, IPR019401, SM00400): Zinc-finger domain
32 NOP56interactor540.89913.735Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
33 NPM1suppressor800.644190.552Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
34 PAN2interactor570.91914.480RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
35 PRDX5interactor30.6671.000Redoxin (PF08534, IPR013740): Redoxin
NAD_binding_10 (PF13460, IPR016040): NAD(P)H-binding
36 PSMC6interactor150.52715.163AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
37 PSMD1interactor160.52514.495PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
38 PSMD2oncoprotein140.39616.681PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
39 PSMD4interactor110.4919.565UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
40 PSMD8interactor120.53012.714CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
41 PYM1interactor260.8743.696CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
Mago-bind (PF09282, IPR015362): Mago binding
AAA_23 (PF13476): AAA domain
42 RACK1suppressor410.79014.707WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
43 RANBP9suppressor100.3894.125Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
LisH (PF08513, IPR013720, SM00667): LisH
SPRY (PF00622, IPR003877, SM00449): SPRY domain
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
44 RNF2interactor500.616115.827zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
45 RPL10suppressor760.77862.284Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
46 RPL10Ainteractor760.82837.874Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
47 RPL10Linteractor560.9522.924Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
Cytochrome_P460 (PF16694, IPR032033): Cytochrome P460
48 RPL11suppressor730.86320.095Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
49 RPL12interactor740.82833.042Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
50 RPL13interactor700.88014.476Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
51 RPL13Ainteractor650.9217.206Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
52 RPL14protein found in more fusions730.84624.265KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
53 RPL15interactor710.87914.490Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
54 RPL18interactor740.84732.583Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
55 RPL18Ainteractor690.86923.390Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
56 RPL19interactor720.84424.835DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
57 RPL21interactor750.82834.108Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
58 RPL22oncoprotein740.82250.571Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
59 RPL23interactor710.86819.647Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
60 RPL23Ainteractor770.80643.964Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
61 RPL24protein found in more fusions750.82286.094MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
62 RPL27protein found in more fusions670.89215.038Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
63 RPL27Ainteractor690.86420.185Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
64 RPL29interactor310.8903.910BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
Ribosomal_L29e (PF01779, IPR002673): Ribosomal L29e protein family
65 RPL3protein found in more fusions690.89511.337Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
66 RPL30interactor680.88315.510NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
67 RPL31interactor700.84925.665Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
68 RPL35interactor660.87526.344Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
XFP_N (PF09364, IPR018970): XFP N-terminal domain
69 RPL35Ainteractor530.9359.414Ribosomal_L35Ae (PF01247, IPR001780): Ribosomal protein L35Ae
70 RPL36interactor690.85529.940Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
71 RPL37Ainteractor670.87618.349Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
72 RPL38protein found in more fusions630.9128.761Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family
73 RPL4interactor750.82834.108Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
74 RPL5suppressor760.84024.651Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
75 RPL6protein found in more fusions740.83926.635Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
76 RPL7interactor760.798120.120Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
77 RPL7Ainteractor750.83029.106Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
78 RPL9interactor740.84327.577Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6
79 RPLP0interactor740.83638.431Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
80 RPS11interactor760.79951.354Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
81 RPS13interactor790.76877.217Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
82 RPS14protein found in more fusions780.76864.986Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
83 RPS15Ainteractor790.76687.096Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
84 RPS16interactor820.75959.915Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
85 RPS19protein found in more fusions780.77464.274Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
86 RPS2interactor820.745102.206Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
87 RPS21interactor640.77198.306Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
88 RPS23protein found in more fusions760.77359.153Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
89 RPS24protein found in more fusions730.78841.973Fascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
90 RPS26interactor730.77657.219Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
91 RPS27protein found in more fusions710.78574.569Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
92 RPS27Ainteractor470.8849.410DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
93 RPS27Linteractor470.86722.445E7 (PF00527, IPR000148): E7 protein, Early protein
Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
94 RPS28interactor610.75560.425Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
95 RPS29interactor350.84011.218Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e
96 RPS3interactor840.722101.098KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
97 RPS3Ainteractor870.692134.856Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
98 RPS4Xinteractor820.75071.707KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
99 RPS5protein found in more fusions780.77663.202Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
100 RPS6protein found in more fusions800.76065.697Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
101 RPS7interactor740.81535.555Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
102 RPS8interactor850.702172.842Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
103 RPS9interactor810.72997.803Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
104 RPSAinteractor780.749116.654Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
105 SIRT7interactor470.61697.535DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
106 SMURF1interactor290.65122.696C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
107 SNW1protein found in more fusions140.37221.202SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
108 SUPT5Hinteractor60.4002.423KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
109 TSR1interactor310.81917.134AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain
RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein
110 UBCprotein found in more fusions250.48946.489ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
111 UBL4Ainteractor600.85236.319ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
112 USP38oncoprotein21.0000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
113 VAMP2interactor21.0000Synaptobrevin (PF00957, IPR001388): Synaptobrevin
PRIMA1 (PF16101): Proline-rich membrane anchor 1
114 VCAM1interactor580.73879.126C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
115 XPO1interactor390.73833.999CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ABL1oncoproteinPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
2 ARHGEF11interactorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RGS-like (PF09128, IPR015212): Regulator of G protein signalling-like domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
3 CARMIL1interactorLRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
IL34 (PF15036, IPR020415): Interleukin 34
CARMIL_C (PF16000, IPR031943): CARMIL C-terminus
4 CDC42oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
5 CDC5LinteractorOmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
6 DLSToncoprotein2-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
7 FBXO25suppressorElongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
8 GGNBP2suppressorSPT2 (PF08243, IPR013256, SM00784): SPT2 chromatin protein
TSLP (PF15216, IPR029189): Thymic stromal lymphopoietin
AP3D1 (PF06375): AP-3 complex subunit delta-1
9 KLHL42interactorBACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
10 LIMK1oncoproteinLIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
11 LOC101929876interactorNA
12 LRRK1interactorRoc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
13 NAA25interactorBTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
NatB_MDM20 (PF09797, IPR019183): N-acetyltransferase B complex (NatB) non catalytic subunit
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
14 NTRK1oncoproteinI-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
15 PAK4parental proteinPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
16 PAK5interactorPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
17 PAK6interactorPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
18 PNO1interactorKH_1 (PF00013, IPR004088, SM00322): KH domain
19 POT1interactorPOT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
20 PPM1BinteractorPP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
21 PXNoncoproteinLIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
22 RAC1oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
23 RANoncoproteinRas (PF00071, IPR001806, SM00173): Ras family
24 RCC2oncoproteinRCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
25 RHOUinteractorRas (PF00071, IPR001806, SM00173): Ras family
SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain
26 RHOVinteractorRas (PF00071, IPR001806, SM00173): Ras family
AAA_25 (PF13481): AAA domain
27 RPL17interactorRibosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
28 RPLP0P6interactorNA
29 RPS10interactorS10_plectin (PF03501, IPR005326): Plectin/S10 domain
30 RPS12parental proteinRibosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
31 RPS18interactorRibosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
32 RPS20interactorRibosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
33 RPS25interactorRibosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
34 SFNsuppressor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
35 SH3RF2interactorSH3_2 (PF07653, IPR011511): Variant SH3 domain
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
SH3_9 (PF14604, IPR001452): Variant SH3 domain
36 SRPK1interactorFYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
37 SRPK2oncoproteinDUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
38 TERF1interactorTRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
39 TMEM17interactorTransmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
40 TMPRSS11AsuppressorSEA (PF01390, IPR000082, SM00200): SEA domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
DUF4179 (PF13786, IPR025436): Domain of unknown function (DUF4179)
41 VCLoncoproteinVinculin (PF01044, IPR006077): Vinculin family
42 YWHABinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
43 YWHAEoncoprotein14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
44 YWHAGinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
45 YWHAQinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
46 YWHAZinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

B a c k    t o    T o p ⇑