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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: CB995744 is the fusion of parental proteins MAPK9, RFTN1 (from a repository: Wed Dec 7 07:27:16 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)97
The number (and %) of the onco-proteins35 (36.08 %)
The number (and %) of the tumor suppressors12 (12.37 %)
Total number of binary PPIs (saturation %)324 (6.96 %)
The number (and %) of affected PPIs96 (29.63 %)
The number of possible different fusions13
PPI diameter2
PPI radius1
The average degree of PPI5.814
Assortativity coefficient-0.4420
The network average Clustering coefficient0.520
The number (and %) of a zero Clustering coefficients22 (22.68 %)
The number (and %) of a zero Betweenness Centrality44 (45.36 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions
PPI for parental proteins: RFTN1,MAPK9 All fusions
: CB995744;
Proteins found in more fusions CTBP1 (see 2 fusions); PRKDC (see 3 fusions); EGFR (see 2 fusions); L3MBTL3 (see 1 fusions); FOS (see 4 fusions); MAPKAPK5 (see 4 fusions); GRB2 (see 1 fusions); MFN2 (see 2 fusions); CSNK1E (see 1 fusions); MAP3K1 (see 1 fusions); CLU (see 5 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient		 Betweenness
Centrality		 Domains (Pfam, InterPro, SMART): description
1 CB995744chimera960.0417628.879Pkinase (PF00069, IPR000719): Protein kinase domain
Kinase-like (PF14531, IPR027916): Kinase-like
2 ACP5interactor100Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
3 AHI1oncoprotein100ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
4 AKT1oncoprotein160.32451.890PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
5 ARRB1interactor110.49114.676Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
6 ARRB2interactor100.51111.240Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
7 ATF2oncoprotein70.6002.929bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
8 BCL10suppressor50.5001.200CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
9 C1orf94interactor31.0000DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
10 CASP3interactor80.4299.400Peptidase_C14 (PF00656, IPR011600): Caspase domain
11 CCDC33interactor21.0000C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
12 CDC25Boncoprotein100M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
13 CDC25Concoprotein30.6670.667M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
14 CDC42oncoprotein100.33314.186Ras (PF00071, IPR001806, SM00173): Ras family
15 CDT1oncoprotein100CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like
CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
16 CEP126interactor100Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
K1377 (PF15352, IPR028257): Susceptibility to monomelic amyotrophy
17 CEP44interactor21.0000DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Utp12 (PF04003, IPR007148): Dip2/Utp12 Family
CEP44 (PF15007, IPR029157): Centrosomal spindle body, CEP44
18 CLUsuppressor50.8330.667Clusterin (PF01093, IPR000753): Clusterin
19 CSNK1Eprotein found in more fusions40.6670.667APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
20 CTBP1protein found in more fusions90.5368.7002-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
21 CTNNB1oncoprotein90.47213.919Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
22 CYHR1interactor21.0000Sina (PF03145, IPR018121): Seven in absentia protein family
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
23 DHX33interactor100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
24 DSG4interactor100Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
25 DTX3oncoprotein100zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
26 DUSP1suppressor30.6670.143DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
27 DUSP10oncoprotein30.6670.143DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
28 DUSP14interactor21.0000DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
29 DUSP16interactor50.7000.976DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
30 DUSP19interactor21.0000DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
31 DUSP4interactor21.0000DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
32 DUSP8interactor21.0000DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
33 EFHC2interactor100DUF1126 (PF06565, IPR010554): Repeat of unknown function (DUF1126)
EF-hand_6 (PF13405, IPR002048): EF-hand domain
34 EGFRoncoprotein210.221120.576Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
35 ELK1oncoprotein50.8330.143Ets (PF00178, IPR000418, SM00413): Ets-domain
Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain
36 FOSoncoprotein90.35712.917bZIP_1 (PF00170, IPR004827): bZIP transcription factor
37 FTH1interactor40.6670.400Coat_F (PF07875, IPR012851): Coat F domain
Ferritin (PF00210, IPR008331): Ferritin-like domain
38 GRB2oncoprotein100.25022.655SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
39 HDAC1suppressor120.47318.412FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
40 HDAC9interactor80.7621.845Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
CEP19 (PF14933, IPR029412): CEP19-like protein
41 HIST1H1Boncoprotein21.0000Pneumo_att_G (PF05539, IPR008781): Pneumovirinae attachment membrane glycoprotein G
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
42 HMGCS1interactor30.6671.000HMG_CoA_synt_C (PF08540, IPR013746): Hydroxymethylglutaryl-coenzyme A synthase C terminal
HMG_CoA_synt_N (PF01154, IPR013528): Hydroxymethylglutaryl-coenzyme A synthase N terminal
43 IRF3suppressor50.8330.400IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
44 JUNoncoprotein210.25897.252bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
45 JUNBoncoprotein30.6670.286bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
46 JUNDoncoprotein40.8330.286bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
47 L3MBTL3protein found in more fusions200CDC45 (PF02724, IPR003874): CDC45-like protein
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Glyco_hydro_2_N (PF02837, IPR006104): Glycosyl hydrolases family 2, sugar binding domain
MBT (PF02820, IPR004092, SM00561): mbt repeat
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
zf-C2HC (PF01530, IPR002515, SM00343): Zinc finger, C2HC type
Calci_bind_CcbP (PF11535, IPR020994): Calcium binding
Apelin (PF15360, IPR026155): APJ endogenous ligand
48 LAMA1interactor100Laminin_B (PF00052, IPR000034): Laminin B (Domain IV)
Laminin_G_1 (PF00054, IPR001791): Laminin G domain
Laminin_I (PF06008, IPR009254): Laminin Domain I
Laminin_II (PF06009, IPR010307): Laminin Domain II
Sec34 (PF04136, IPR007265): Sec34-like family
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
49 LMAN2interactor100Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Tad (PF13400, IPR028087): Putative Flp pilus-assembly TadE/G-like
50 LNX1interactor70.4007.733PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
51 LNX2interactor41.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DZR (PF12773, IPR025874): Double zinc ribbon
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
52 LRRC15interactor100CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
53 MACF1oncoprotein21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
CTV_P33 (PF07184, IPR010803): Citrus tristeza virus P33 protein
DnaI_N (PF07319, IPR009928): Primosomal protein DnaI N-terminus
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF19 (PF01579, IPR002542): Domain of unknown function (DUF19)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Peptidase_S49 (PF01343, IPR002142): Peptidase family S49
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
SYF2 (PF08231, IPR013260): SYF2 splicing factor
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
DUF3813 (PF12758, IPR024217): Protein of unknown function (DUF3813)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
TEX12 (PF15219, IPR029193): Testis-expressed 12
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
54 MAP2K4suppressor130.53014.833Pkinase (PF00069, IPR000719): Protein kinase domain
55 MAP2K7interactor100.48916.619Pkinase (PF00069, IPR000719): Protein kinase domain
56 MAP3K1oncoprotein120.47314.869zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
57 MAP3K10interactor60.5002.686Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
58 MAPK10suppressor180.22873.083Pkinase (PF00069, IPR000719): Protein kinase domain
59 MAPK8oncoprotein360.145419.626DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
60 MAPK8IP1oncoprotein100.5288.502PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
61 MAPK8IP2interactor100.41714.133BUD22 (PF09073, IPR015158): BUD22
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
SH3_9 (PF14604, IPR001452): Variant SH3 domain
62 MAPK8IP3interactor70.7142.162Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
63 MAPKAPK5protein found in more fusions31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
64 MEOX1interactor100Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
65 MFN2protein found in more fusions200Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
66 NCF1interactor31.0000p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain
PX (PF00787, IPR001683, SM00312): PX domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1
67 NFATC2suppressor41.0000RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
68 NFATC3oncoprotein21.0000DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
69 NFATC4interactor31.0000RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
70 NFE2L2oncoprotein50.8000.619bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
71 PKN1interactor60.4005.167C2 (PF00168, IPR000008, SM00239): C2 domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
72 PKP3interactor100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383)
73 PPM1Asuppressor50.7003.000PP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
74 PRKD1oncoprotein50.8330.250PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
75 PRKDCprotein found in more fusions90.5009.352FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
76 SCLT1oncoprotein30.6671.000DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
XhlA (PF10779, IPR019715): Haemolysin XhlA
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Imm7 (PF15585, IPR028965): Immunity protein 7
CCCAP (PF15964, IPR031887): Centrosomal colon cancer autoantigen protein family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
77 SEC13interactor40.6670.667WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
78 SERPINB5suppressor40.5002.333Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
79 SF3B4interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
80 SH3BP5interactor30.6670.143SH3BP5 (PF05276, IPR007940): SH3 domain-binding protein 5 (SH3BP5)
81 SHMT1interactor200SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
82 SMCO3interactor100DUF4533 (PF15047, IPR027895): Protein of unknown function (DUF4533)
83 SPTAN1oncoprotein40.6671.333EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
84 SSU72interactor30.6670.286Ssu72 (PF04722, IPR006811): Ssu72-like protein
85 STILoncoprotein100STIL_N (PF15253, IPR026123): SCL-interrupting locus protein N-terminus
86 STK25interactor21.0000DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
87 STK26interactor40.6671.000DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
88 TEX11interactor100SPO22 (PF08631, IPR013940): Meiosis protein SPO22/ZIP4 like
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2547 (PF10818, IPR020508): Protein of unknown function (DUF2547)
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
AAA_28 (PF13521): AAA domain
TPR_19 (PF14559): Tetratricopeptide repeat
89 TOB1interactor21.0000PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
BTG (PF07742, IPR002087, SM00099): BTG family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
90 TP53suppressor150.29747.936DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
91 TRAF2interactor150.22062.071MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
92 TUSC2suppressor100TUSC2 (PF15000, IPR029393): Tumour suppressor candidate 2
93 VSIG8interactor100V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
94 WDR62interactor50.5002.143eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
95 XPNPEP1interactor21.0000Creatinase_N (PF01321, IPR000587): Creatinase/Prolidase N-terminal domain
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Peptidase_M24_C (PF16188, IPR032416): C-terminal region of peptidase_M24
Creatinase_N_2 (PF16189): Creatinase/Prolidase N-terminal domain
96 XPO7interactor21.0000IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
97 ZBTB25interactor31.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 MAPK9parental proteinPkinase (PF00069, IPR000719): Protein kinase domain
Kinase-like (PF14531, IPR027916): Kinase-like
2 MUS81suppressorERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
MutL (PF13941, IPR006230): MutL protein
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
3 PTENsuppressorDSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
4 RFTN1parental proteinRaftlin (PF15250, IPR028169): Raftlin
5 SLC25A41interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
6 UNC119interactorGMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit

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