Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: CB147232 is the fusion of parental proteins GAPDH, SERPINA1 (from a repository: Thu Dec 8 15:24:29 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)210
The number (and %) of the onco-proteins73 (34.76 %)
The number (and %) of the tumor suppressors32 (15.24 %)
Total number of binary PPIs (saturation %)2216 (10.10 %)
The number (and %) of affected PPIs209 (9.43 %)
The number of possible different fusions48
PPI diameter2
PPI radius1
The average degree of PPI20.219
Assortativity coefficient-0.2019
The network average Clustering coefficient0.481
The number (and %) of a zero Clustering coefficients13 (6.19 %)
The number (and %) of a zero Betweenness Centrality29 (13.81 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: SERPINA1,GAPDH All fusions
: CB147232;
Proteins found in more fusions CTBP1 (see 2 fusions); SMAD4 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); GRB2 (see 1 fusions); UBQLN1 (see 2 fusions); EWSR1 (see 2 fusions); PRDX1 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); MAP3K5 (see 1 fusions); RPA1 (see 1 fusions); APP (see 4 fusions); POU2F1 (see 1 fusions); VCP (see 4 fusions); TKT (see 5 fusions); HSP90AA1 (see 2 fusions); HUWE1 (see 2 fusions); HSP90AB1 (see 1 fusions); GAS7 (see 1 fusions); PTK2 (see 2 fusions); ECHS1 (see 1 fusions); HSPA8/HSPD1 (see 1 fusions); USP25 (see 1 fusions); STAU1 (see 2 fusions); MAPK1 (see 1 fusions); EEF1A1 (see 1 fusions); CBL (see 1 fusions); GSK3B (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); HTT (see 1 fusions); COPS5 (see 1 fusions); OS9 (see 2 fusions); PRPF40A (see 2 fusions); TP53 (see 3 fusions); AP2M1 (see 3 fusions); FUS/PKM (see 1 fusions); ATXN1 (see 3 fusions); SIAH1 (see 4 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); POU2F2 (see 5 fusions); KAT5 (see 3 fusions); CFL1/EED (see 1 fusions); ATN1 (see 1 fusions); SDC2 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CB147232chimera2090.08823769.394Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
2 ACDinteractor80.7501.869TPP1 (PF10341, IPR019437): Shelterin complex subunit, TPP1/ACD
3 ACOT7interactor80.4298.2714HBT (PF03061, IPR006683): Thioesterase superfamily
NINJA_B (PF16136, IPR032310): Putative nuclear localisation signal
4 ACTC1interactor70.3814.087Actin (PF00022, IPR004000, SM00268): Actin
5 ADRB2interactor190.35925.8947tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
6 AKR1A1interactor80.6074.033Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
7 AKT1oncoprotein290.37372.954PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
8 ALDH2oncoprotein60.6672.031Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
DUF1235 (PF06822, IPR009641): Protein of unknown function (DUF1235)
9 ALDOAinteractor410.329197.549Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
10 ANKRD36interactor100DUF573 (PF04504, IPR007592): Protein of unknown function, DUF573
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
IncA (PF04156, IPR007285): IncA protein
Mnd1 (PF03962, IPR005647): Mnd1 family
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4150 (PF13665, IPR025425): Domain of unknown function (DUF4150)
CCDC144C (PF14915): CCDC144C protein coiled-coil region
UPF0693 (PF16088, IPR032143): UPF0693 family
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
11 AP2M1protein found in more fusions180.6107.307Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
12 APPprotein found in more fusions650.1441120.244APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
13 ARoncoprotein220.30077.793Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
14 ARL15interactor100Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
15 ARRB2interactor260.37862.344Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
16 ASB15interactor100Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
17 ASB16interactor100Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
18 ASPSCR1oncoprotein40.6670.160DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
UBX (PF00789, IPR001012, SM00166): UBX domain
TUG-UBL1 (PF11470, IPR021569): TUG ubiquitin-like domain
19 ASS1suppressor140.5006.875Arginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase
20 ATF2oncoprotein200.36832.019bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
21 ATN1protein found in more fusions70.3336.106Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
22 ATP5C1interactor170.35321.798ATP-synt (PF00231, IPR000131): ATP synthase
ACT_4 (PF13291, IPR002912): ACT domain
23 ATXN1protein found in more fusions60.5001.451AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
24 BIDoncoprotein60.7000.315BID (PF06393, IPR010479): BH3 interacting domain (BID)
25 BLKoncoprotein50.7000.797Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
26 BTBD2interactor70.8100.305BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PHR (PF08005, IPR012983): PHR domain
27 BTKsuppressor70.5331.215BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
28 CAND1interactor390.50276.239Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
29 CANXinteractor220.44622.787Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
30 CAPNS1interactor110.25519.518EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
31 CBLsuppressor180.42630.836Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
32 CCDC8interactor320.43260.887Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
33 CCNB1oncoprotein140.44012.583Adeno_E1A (PF02703, IPR003853): Early E1A protein
Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
34 CD4suppressor130.6213.377ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
35 CD81interactor210.34737.187Tetraspannin (PF00335, IPR018499): Tetraspanin family
36 CDC5Linteractor400.354189.570OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
37 CDK17interactor30.6670.400Pkinase (PF00069, IPR000719): Protein kinase domain
38 CDK2suppressor530.338324.474Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
39 CDKN1Asuppressor300.45162.069CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
40 CDKN2Asuppressor210.54824.172Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
41 CFL1protein found in more fusions370.335173.982Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
42 COPS5protein found in more fusions500.384276.661JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
43 COPS6interactor340.40994.404DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
44 CRYZinteractor21.0000ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
45 CSTF3interactor60.8670.139NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
46 CTBP1protein found in more fusions110.4448.1092-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
47 CUL1suppressor480.460129.888Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
48 CUL2suppressor400.415140.614Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
49 CUL3protein found in more fusions620.313472.541Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
50 CUL4Boncoprotein340.56034.151Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
51 CUL7protein found in more fusions420.295185.505ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
52 DCPSinteractor90.5287.110DcpS (PF05652, IPR008594): Scavenger mRNA decapping enzyme (DcpS) N-terminal
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
53 DDX19Binteractor70.4296.414DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
54 DERL1interactor70.6002.591DER1 (PF04511, IPR007599): Der1-like family
55 DERL2interactor60.6003.733DER1 (PF04511, IPR007599): Der1-like family
56 DFFAsuppressor80.5714.617CIDE-N (PF02017, IPR003508): CIDE-N domain
DFF-C (PF09033, IPR015121): DNA Fragmentation factor 45kDa, C terminal domain
T2SSppdC (PF12528, IPR022204): Type II secretion prepilin peptidase dependent protein C
SAPIS-gp6 (PF16722, IPR031999): Pathogenicity island protein gp6 in Staphylococcus
57 DPYDinteractor100DHO_dh (PF01180, IPR012135): Dihydroorotate dehydrogenase
Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain
Fer4_20 (PF14691, IPR028261): Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
Fer4_21 (PF14697): 4Fe-4S dicluster domain
58 DTNBinteractor31.0000EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
SOGA (PF11365, IPR027881): Protein SOGA
59 DUTinteractor200.43730.792dUTPase (PF00692, IPR008180): dUTPase
60 ECHS1protein found in more fusions120.40014.381ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
61 EEDsuppressor200.42126.379WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
62 EEF1A1suppressor730.233828.096GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
63 EGFRoncoprotein520.267403.408Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
64 ELANEinteractor100Trypsin (PF00089, IPR001254, SM00020): Trypsin
65 ENO1oncoprotein500.298266.200Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
66 ENO2interactor240.40954.740Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
67 ENO3interactor160.48317.871Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
68 EP300oncoprotein300.328101.555Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
69 ERLEC1interactor50.8000.900PRKCSH (PF07915, IPR012913): Glucosidase II beta subunit-like protein
PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
70 ESR1suppressor420.309220.123Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
71 ESRRBsuppressor170.5519.651zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
72 EWSR1oncoprotein520.304338.930RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
73 FBXO2interactor50.7000.438FBA (PF04300, IPR007397): F-box associated region
F-box (PF00646, IPR001810, SM00256): F-box domain
74 FBXO6interactor380.347135.603FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
75 FERMT2interactor100.40015.414FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
76 FN1oncoprotein490.295301.963fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
77 FUSsuppressor480.51788.837Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
78 GADD45Asuppressor110.6443.259Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
79 GAPDHSinteractor21.0000Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
80 GAS7oncoprotein200DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
WW (PF00397, IPR001202, SM00456): WW domain
YscO (PF07321, IPR009929): Type III secretion protein YscO
SH3_9 (PF14604, IPR001452): Variant SH3 domain
WW_FCH_linker (PF16623): Unstructured linker region between on GAS7 protein
81 GBP1suppressor40.5002.167GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain
GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
82 GDPD1interactor100GDPD (PF03009, IPR004129): Glycerophosphoryl diester phosphodiesterase family
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
83 GLOD4interactor70.5711.759Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
84 GOT2oncoprotein60.8000.257Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
85 GPD1Linteractor30.6670.118NAD_Gly3P_dh_C (PF07479, IPR006109): NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
86 GRB2oncoprotein340.41795.679SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
87 GSDMBinteractor21.0000Gasdermin (PF04598, IPR007677): Gasdermin family
88 GSK3Bsuppressor160.47619.250Pkinase (PF00069, IPR000719): Protein kinase domain
89 HES1oncoprotein40.8330.500Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
90 HNF4Ginteractor21.0000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
91 HNRNPA1interactor590.393258.109RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
92 HNRNPA3oncoprotein310.47142.978IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
93 HSP90AA1oncoprotein730.277835.001HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
94 HSP90AB1oncoprotein550.379246.657HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
95 HSPA1Linteractor280.34463.379HSP70 (PF00012, IPR013126): Hsp70 protein
96 HSPA5oncoprotein620.318432.200HSP70 (PF00012, IPR013126): Hsp70 protein
97 HSPA8oncoprotein650.328425.315HSP70 (PF00012, IPR013126): Hsp70 protein
98 HSPA9oncoprotein520.320252.232HSP70 (PF00012, IPR013126): Hsp70 protein
99 HSPB2interactor100.33312.907Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
100 HSPD1suppressor450.368182.330Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
101 HTTprotein found in more fusions160.44827.673HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
102 HUWE1oncoprotein400.356156.326BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
103 ICAM1oncoprotein70.3811.606Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
104 ICE2interactor100NARG2_C (PF10505, IPR019535): NMDA receptor-regulated gene protein 2 C-terminus
CLAMP (PF14769, IPR032727): Flagellar C1a complex subunit C1a-32
105 IQCB1interactor200.37933.398DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
106 ISG15suppressor170.44924.319ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
107 ITGA4interactor360.380115.374FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
108 KARSinteractor130.4749.142tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
109 KAT5suppressor160.51414.956MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
110 KLK3interactor40.6670.515Trypsin (PF00089, IPR001254, SM00020): Trypsin
111 KNL1oncoprotein30.6670.500DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
112 LAMA4interactor40.6670.157DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ZapB (PF06005, IPR009252): Cell division protein ZapB
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
Laminin_I (PF06008, IPR009254): Laminin Domain I
Laminin_II (PF06009, IPR010307): Laminin Domain II
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
113 LAMTOR5interactor40.8330.053LAMTOR5 (PF16672, IPR024135): Ragulator complex protein LAMTOR5
114 LIG4interactor70.5244.514APG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
115 MAP3K5oncoprotein120.41810.941Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
116 MAPK1oncoprotein190.31435.902Pkinase (PF00069, IPR000719): Protein kinase domain
117 MAPK7oncoprotein100.7780.648Pkinase (PF00069, IPR000719): Protein kinase domain
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
118 MAT2Binteractor80.6074.578RmlD_sub_bind (PF04321, IPR005913): RmlD substrate binding domain
119 MCM2oncoprotein640.312444.056AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
120 MCM5oncoprotein300.49439.428MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
121 MDM2oncoprotein390.334175.173Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
122 MED8interactor60.4671.051Med8 (PF10232, IPR019364): Mediator of RNA polymerase II transcription complex subunit 8
123 METAP2oncoprotein40.5001.398Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
124 MIS12interactor40.6671.333DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
Mis12 (PF05859, IPR008685): Mis12 protein
125 MSRB3interactor100SelR (PF01641, IPR002579): SelR domain
126 MYOCinteractor90.7141.439IncA (PF04156, IPR007285): IncA protein
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
127 NEDD8interactor280.58437.363ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
128 NFYCinteractor21.0000CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Fucose_iso_C (PF02952, IPR015888): L-fucose isomerase, C-terminal domain
129 NLRP2oncoprotein31.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
AAA_16 (PF13191): AAA ATPase domain
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
130 NPATinteractor40.6670.633Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
NPAT_C (PF15712, IPR031442): NPAT C terminus
131 NPM1suppressor550.358246.405Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
132 NR1H4interactor41.0000LRV_FeS (PF05484, IPR008665): LRV protein FeS4 cluster
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
133 NTRK1oncoprotein810.2271110.220I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
134 NUDCinteractor130.35920.461CS (PF04969, IPR007052): CS domain
D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc.
NuDC (PF16273, IPR032572): Nuclear distribution C domain
135 OBSL1interactor280.49027.360BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
136 OLA1interactor80.5362.798Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933)
137 OS9protein found in more fusions90.6434.446DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87
PRKCSH (PF07915, IPR012913): Glucosidase II beta subunit-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
138 OSMRinteractor21.0000EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
139 OSTF1interactor40.5000.869SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
140 PABPN1interactor110.7272.391RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Shadoo (PF14999, IPR029238): Shadow of prion protein, neuroprotective
141 PAFAH1B3interactor100.4443.521Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family
142 PARK2suppressor350.36281.848IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
143 PCDHA4interactor31.0000Cadherin_2 (PF08266, IPR013164): Cadherin-like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_tail (PF15974, IPR031904): Cadherin C-terminal cytoplasmic tail, catenin-binding region
Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
144 PCNAoncoprotein360.37394.188PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
145 PDIA2interactor21.0000Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
146 PGK1interactor280.52440.025PGK (PF00162, IPR001576): Phosphoglycerate kinase
147 PKMoncoprotein510.344251.259PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
148 PLD2interactor50.6001.145PH (PF00169, IPR001849, SM00233): PH domain
PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif
PX (PF00787, IPR001683, SM00312): PX domain
PLDc_2 (PF13091, IPR025202): PLD-like domain
149 PLK2suppressor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
150 POT1interactor140.44918.208POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
151 POU2F1protein found in more fusions80.5244.014Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
152 POU2F2oncoprotein40.6670.143Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
153 POU5F1oncoprotein160.37122.575Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
154 PPIBinteractor210.32948.725Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
155 PPP2R2Ainteractor70.6194.201WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
156 PPP4R3Ainteractor40.6670.536Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1
WH1 (PF00568, IPR000697, SM00461): WH1 domain
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
157 PPP5Cinteractor200.40042.473Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PPP5 (PF08321, IPR013235): PPP5 TPR repeat region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
158 PRDX1oncoprotein400.312149.955AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
159 PRDX2interactor240.37056.117AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
160 PRDX5interactor100.5565.277Redoxin (PF08534, IPR013740): Redoxin
NAD_binding_10 (PF13460, IPR016040): NAD(P)H-binding
161 PRKCIinteractor41.0000PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
162 PRPF40Aprotein found in more fusions170.34226.374FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
163 PRTN3interactor100Trypsin (PF00089, IPR001254, SM00020): Trypsin
164 PSEN1oncoprotein70.6002.767Presenilin (PF01080, IPR001108): Presenilin
LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain
165 PSMA3interactor340.45676.492Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
166 PSMD11interactor170.39016.329DUF247 (PF03140, IPR004158): Plant protein of unknown function
PCI (PF01399, IPR000717, SM00088): PCI domain
AAA_16 (PF13191): AAA ATPase domain
TPR_12 (PF13424): Tetratricopeptide repeat
167 PSMD3interactor160.41714.801Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
168 PTK2protein found in more fusions130.51511.256FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
169 QRICH2interactor100Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
GLTT (PF01744, IPR008164): GLTT repeat (6 copies)
Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
DUF4795 (PF16043, IPR032013): Domain of unknown function (DUF4795)
170 RAD52oncoprotein140.4366.824Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
171 RAP1GDS1oncoprotein120.47013.063Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
172 RBM5suppressor30.6670.400DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
173 RCHY1suppressor70.7333.333C1_2 (PF03107, IPR004146): C1 domain
zf-CHY (PF05495, IPR008913): CHY zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zinc_ribbon_6 (PF14599): Zinc-ribbon
174 RPA1suppressor340.47967.479Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
175 RPA2oncoprotein300.52043.237RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
176 RPA3interactor240.60914.599Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
177 SDC2protein found in more fusions31.0000Glycophorin_A (PF01102, IPR001195): Glycophorin A
Syndecan (PF01034, IPR027789): Syndecan domain
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
178 SERPINB9interactor80.5003.150Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
179 SEToncoprotein170.32519.406NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
180 SIAH1suppressor100.38910.659Sina (PF03145, IPR018121): Seven in absentia protein family
181 SIRT1suppressor220.36760.555DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
182 SIRT6suppressor80.5711.611SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
183 SLC2A4interactor21.0000Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
184 SMAD4suppressor140.38516.456MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
185 SMN1interactor140.5008.010SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
186 SNCAinteractor180.44133.676Synuclein (PF01387, IPR001058): Synuclein
187 SOD1interactor200.34544.762Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
188 SSR1interactor100.6891.782TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
189 STAU1protein found in more fusions320.46554.636dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
190 STIP1interactor330.348126.305TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
191 TACO1interactor21.0000Transcrip_reg (PF01709, IPR002876): Transcriptional regulator
192 TANGO2interactor50.7000.606TANGO2 (PF05742, IPR008551): Transport and Golgi organisation 2
193 TERF1interactor240.28998.345TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
194 TINF2interactor110.5787.071TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus
195 TK1oncoprotein110.5332.676TK (PF00265, IPR001267, SM00203): Thymidine kinase
196 TKTprotein found in more fusions300.44167.505Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
197 TP53suppressor550.263454.032DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
198 TPI1interactor290.36280.894TIM (PF00121, IPR000652): Triosephosphate isomerase
199 TRAP1oncoprotein180.45818.547HSP90 (PF00183, IPR001404): Hsp90 protein
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
200 TUBA1Aoncoprotein310.312105.296Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
201 TUBA1Cinteractor390.39582.831Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
202 TUBBinteractor580.306398.411Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
203 TUFMinteractor250.37737.028GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
204 TXNoncoprotein280.39978.039Thioredoxin (PF00085, IPR013766): Thioredoxin
205 TYMPoncoprotein40.6670.333Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Glycos_transf_3 (PF00591, IPR000312): Glycosyl transferase family, a/b domain
PYNP_C (PF07831, IPR013102, SM00941): Pyrimidine nucleoside phosphorylase C-terminal domain
206 UBQLN1protein found in more fusions150.26431.926Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X
207 USP25protein found in more fusions60.8000.300UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UBA_4 (PF14555): UBA-like domain
208 VCAM1interactor320.40362.364C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
209 VCPprotein found in more fusions580.296499.453AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
210 ZNF558interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ANXA1suppressorAnnexin (PF00191, IPR018502, SM00335): Annexin
2 ANXA7suppressorAnnexin (PF00191, IPR018502, SM00335): Annexin
3 CA8interactorCarb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
4 GAPDHparental proteinGp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
5 GDPGP1interactorNA
6 KCNE3interactorISK_Channel (PF02060, IPR000369): Slow voltage-gated potassium channel
7 PGAM1interactorHis_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
8 PGAM2interactorHis_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
9 PPME1interactorAbhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
10 PRKYinteractorNA
11 RAP2AoncoproteinRas (PF00071, IPR001806, SM00173): Ras family
12 SERPINA1parental proteinSerpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
13 VKORC1interactorVKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family
14 YWHAEoncoprotein14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
15 YWHAGinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
16 YWHAQinteractor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

B a c k    t o    T o p ⇑