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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: CB114948 is the fusion of parental proteins RAC1, CCT3 (from a repository: Sun Dec 18 06:54:41 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)268
The number (and %) of the onco-proteins91 (33.96 %)
The number (and %) of the tumor suppressors35 (13.06 %)
Total number of binary PPIs (saturation %)2710 (7.57 %)
The number (and %) of affected PPIs267 (9.85 %)
The number of possible different fusions46
PPI diameter2
PPI radius1
The average degree of PPI19.455
Assortativity coefficient-0.2598
The network average Clustering coefficient0.525
The number (and %) of a zero Clustering coefficients10 (3.73 %)
The number (and %) of a zero Betweenness Centrality41 (15.30 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: RAC1,CCT3 All fusions
: CB114948;
Proteins found in more fusions EEF1G (see 1 fusions); GRB2 (see 1 fusions); LGALS3BP (see 2 fusions); VHL (see 1 fusions); ARF1 (see 2 fusions); LGALS3 (see 2 fusions); SH3RF1 (see 1 fusions); GAN (see 1 fusions); FANCA (see 1 fusions); HDAC5 (see 1 fusions); NEDD4 (see 1 fusions); SUZ12 (see 2 fusions); SNW1 (see 1 fusions); TNF (see 1 fusions); VCP (see 4 fusions); SFPQ (see 6 fusions); HUWE1 (see 2 fusions); PAK4 (see 1 fusions); LDHA/SKI (see 3 fusions); STAT3 (see 2 fusions); FMNL1 (see 1 fusions); COPA (see 2 fusions); PTK2 (see 2 fusions); ERRFI1 (see 1 fusions); SH3BP4 (see 2 fusions); TUBG1 (see 1 fusions); RBMX (see 3 fusions); EPS15 (see 1 fusions); EEF1A1 (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); ACTB (see 3 fusions); SKI (see 1 fusions); PEX14 (see 1 fusions); PAK2 (see 2 fusions); UBC (see 1 fusions); LRRK2 (see 1 fusions); TP53 (see 3 fusions); ILK (see 1 fusions); MCM7 (see 2 fusions); TRIM28 (see 1 fusions); KPNB1 (see 2 fusions); MCM2 (see 1 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CB114948chimera2680.06641182.493Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
2 ACACAinteractor130.39712.643ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region
Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
3 ACTBoncoprotein400.332168.315Actin (PF00022, IPR004000, SM00268): Actin
4 ACTL6Ainteractor170.6259.301Actin (PF00022, IPR004000, SM00268): Actin
5 ACTR1Binteractor120.54514.246Actin (PF00022, IPR004000, SM00268): Actin
6 ACTR2interactor250.55734.716Actin (PF00022, IPR004000, SM00268): Actin
7 AGO3interactor60.6000.857ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
8 AHSA1interactor250.45042.087Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
9 AMBRA1interactor150.57113.233Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
10 ANXA11interactor70.4293.130Annexin (PF00191, IPR018502, SM00335): Annexin
11 ARF1suppressor170.45024.315Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
12 ARFIP2interactor40.6671.000Arfaptin (PF06456, IPR010504, SM01015): Arfaptin-like domain
13 ARHGAP27interactor100PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
WW (PF00397, IPR001202, SM00456): WW domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
14 ARHGAP32oncoprotein40.8330.286PX (PF00787, IPR001683, SM00312): PX domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RPEL (PF02755, IPR004018, SM00707): RPEL repeat
SH3_9 (PF14604, IPR001452): Variant SH3 domain
15 ARHGAP33interactor100PX (PF00787, IPR001683, SM00312): PX domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
16 ARHGAP35oncoprotein31.0000FF (PF01846, IPR002713, SM00441): FF domain
Ras (PF00071, IPR001806, SM00173): Ras family
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGAP-FF1 (PF16512, IPR032835): p190-A and -B Rho GAPs FF domain
17 ARHGEF2oncoprotein120.34812.631IncA (PF04156, IPR007285): IncA protein
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
18 ARHGEF4oncoprotein100PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
19 ARHGEF6oncoprotein41.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7
RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7
20 ARMC6interactor91.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
21 ATF2oncoprotein150.48411.066bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
22 ATG16L1interactor70.6670.911ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332)
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
23 B9D1interactor110.8002.848Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
24 BAG6interactor180.19167.018DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
25 BAIAP2interactor40.6670.500IMD (PF08397, IPR013606): IRSp53/MIM homology domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
26 BCRsuppressor80.5363.018Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
27 BIRC2oncoprotein100.41712.984BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
28 BMI1oncoprotein180.31637.421zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
29 BRINP1suppressor60.4672.308MACPF (PF01823, IPR020864, SM00457): MAC/Perforin domain
30 BTRConcoprotein230.38174.371WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
31 C1QAoncoprotein31.0000C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
32 CADoncoprotein400.351152.235Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MGS (PF02142, IPR011607, SM00851): MGS-like domain
OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
33 CAMKMTinteractor50.9000.200Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
34 CANXinteractor280.38976.848Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
35 CCDC8interactor460.281184.623Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
36 CCT2interactor1120.1831730.926Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
37 CCT4interactor1050.1801600.273Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
38 CCT5interactor920.219925.860Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
39 CCT6Ainteractor1120.1811750.685Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
40 CCT6Binteractor380.290226.764Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
41 CCT7interactor1050.1831496.413Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
42 CCT8interactor1030.1951345.819Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
43 CD81interactor170.26744.251Tetraspannin (PF00335, IPR018499): Tetraspanin family
44 CDC20oncoprotein210.67911.266WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
45 CDC42BPGinteractor100CNH (PF00780, IPR001180, SM00036): CNH domain
DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like
ZapB (PF06005, IPR009252): Cell division protein ZapB
IncA (PF04156, IPR007285): IncA protein
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
PH (PF00169, IPR001849, SM00233): PH domain
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
XkdW (PF09636, IPR019094): XkdW protein
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
46 CDC5Linteractor480.317297.535OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
47 CDK13interactor50.6000.607K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Macoilin (PF09726, IPR019130): Transmembrane protein
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
48 CDK2suppressor520.271284.431Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
49 CDK5oncoprotein150.57114.547Pkinase (PF00069, IPR000719): Protein kinase domain
50 CDK9protein found in more fusions180.39725.823Pkinase (PF00069, IPR000719): Protein kinase domain
51 CETN2interactor71.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
52 CFTRsuppressor180.26546.247ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
53 CHN2interactor21.0000RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DUF4127 (PF13552, IPR025394): Protein of unknown function (DUF4127)
54 CITinteractor31.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CNH (PF00780, IPR001180, SM00036): CNH domain
Dec-1 (PF04624, IPR006718): Dec-1 repeat
DivIC (PF04977, IPR007060): Septum formation initiator
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fez1 (PF06818): Fez1
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SlyX (PF04102, IPR007236): SlyX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
55 CLIP1oncoprotein30.6670.286ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
CP12 (PF02672, IPR003823, SM01093): CP12 domain
DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
SlyX (PF04102, IPR007236): SlyX
ApoO (PF09769, IPR019166): Apolipoprotein O
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Leu_zip (PF15294): Leucine zipper
CLIP1_ZNF (PF16641, IPR032108): CLIP1 zinc knuckle
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
56 CLTConcoprotein370.315164.555Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
57 COPAprotein found in more fusions180.34617.144Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region
COPI_C (PF06957, IPR010714): Coatomer (COPI) alpha subunit C-terminus
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
58 CORO1Concoprotein150.50517.855DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
59 CTTNBP2interactor130.8852.608Carmo_coat_C (PF08462, IPR013669): Carmovirus coat protein
CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
60 CUL3protein found in more fusions640.253522.673Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
61 CUL7protein found in more fusions560.253334.726ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
62 CYP27A1interactor40.8330.400p450 (PF00067, IPR001128): Cytochrome P450
63 DAZAP1interactor100.3334.338RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
64 DCAF5interactor70.9050.194WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
65 DDX3Xsuppressor310.202107.216DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
66 DEF6interactor21.0000ArgK (PF03308, IPR005129): ArgK protein
HSP70 (PF00012, IPR013126): Hsp70 protein
PH (PF00169, IPR001849, SM00233): PH domain
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
67 DMPKinteractor100AP_endonuc_2 (PF01261, IPR013022): Xylose isomerase-like TIM barrel
DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like
Pkinase (PF00069, IPR000719): Protein kinase domain
68 DNAJA1interactor450.241289.838DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
69 DNAJA4interactor120.48513.113DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
70 DNAJC7interactor130.4875.867DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_17 (PF13431): Tetratricopeptide repeat
71 DOCK1interactor60.6001.682DHR-2 (PF06920, IPR010703): Dock homology region 2
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
TetR_C_8 (PF14278): Transcriptional regulator C-terminal region
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DOCK_N (PF16172, IPR032376): DOCK N-terminus
72 DOCK2oncoprotein60.4005.217DHR-2 (PF06920, IPR010703): Dock homology region 2
DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DOCK_N (PF16172, IPR032376): DOCK N-terminus
73 EEDsuppressor250.25471.559WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
74 EEF1A1suppressor360.309120.638GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
75 EEF1Gprotein found in more fusions290.30480.820EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
76 EHD2interactor60.8000.265Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein
77 EPS15oncoprotein150.57115.542Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
78 ERRFI1suppressor60.8000.277GTPase_binding (PF09027, IPR015116): GTPase binding
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
79 ETFAinteractor120.4858.803ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain
ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain
80 ETFBKMTinteractor31.0000PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
81 FAM86B2interactor100.9560.194Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
FAM86 (PF14904, IPR029426): Family of unknown function
82 FANCAoncoprotein50.5000.431Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
83 FBXO6interactor460.231290.847FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
84 FBXW4oncoprotein120.7125.211WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
F-box-like (PF12937, IPR001810): F-box-like
F-box_4 (PF15966, IPR001810): F-box
85 FBXW7suppressor130.30315.426Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
86 FBXW8interactor120.7732.434WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
87 FMNL1protein found in more fusions60.4002.875CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
SlyX (PF04102, IPR007236): SlyX
FNIP_M (PF14637, IPR028085): Folliculin-interacting protein middle domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
88 FN1oncoprotein570.234415.093fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
89 FUSsuppressor400.464101.911Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
90 FYCO1interactor70.7621.063Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region
RUN (PF02759, IPR004012, SM00593): RUN domain
Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
91 GANprotein found in more fusions130.8033.857BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
92 GBAinteractor90.5833.767Glyco_hydro_30 (PF02055, IPR001139): Glycosyl hydrolase family 30 TIM-barrel domain
Glyco_hydro_30C (PF17189): Glycosyl hydrolase family 30 beta sandwich domain
93 GIT1interactor90.46411.800ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT
GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
FlxA (PF14282, IPR025577): FlxA-like protein
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
94 GNB5interactor51.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
95 GRB2oncoprotein450.298379.997SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
96 GRNoncoprotein110.2918.483Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
97 HACE1suppressor31.0000HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
98 HDAC1suppressor290.38991.806FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
99 HDAC11interactor90.5006.857Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
100 HDAC3suppressor180.57419.696Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
101 HDAC5protein found in more fusions420.329131.516Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
102 HDAC6oncoprotein230.32068.471Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
103 HIST1H3Ainteractor190.27552.741Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
104 HSP90B1suppressor380.266241.413CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
105 HUWE1oncoprotein490.351226.673BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
106 ICAM1oncoprotein70.4292.933Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
107 IGBP1interactor150.64818.649TAP42 (PF04177, IPR007304): TAP42-like family
108 IGSF8oncoprotein80.5003.809V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
109 IKBKEinteractor160.43830.314IncA (PF04156, IPR007285): IncA protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
110 IL1RAPinteractor50.7002.000ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
TIR (PF01582, IPR000157, SM00255): TIR domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
111 ILKsuppressor240.47028.382Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
112 INPPL1oncoprotein140.46218.249Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
113 IQGAP1interactor370.323178.170CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
114 IQGAP2suppressor30.6670.222CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
115 IQGAP3interactor31.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
SHD1 (PF03983, IPR007131): SLA1 homology domain 1, SHD1
116 IRAK1interactor190.50342.843Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
117 ISG15suppressor160.26724.596ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
118 ITGA4interactor530.272279.612FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
119 JAK3oncoprotein90.6674.916Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
120 KALRNoncoprotein21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Spectrin (PF00435, IPR002017): Spectrin repeat
UPF0302 (PF08864, IPR014963): UPF0302 domain
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
HAD_2 (PF13419, IPR023214): Haloacid dehalogenase-like hydrolase
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PH_10 (PF15411): Pleckstrin homology domain
SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region
121 KIF21Ainteractor120.8486.500DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690)
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Strep_SA_rep (PF06696, IPR009578): Streptococcal surface antigen repeat
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
122 KPNA2interactor260.34577.163Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
123 KPNA4interactor200.46325.643Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
124 KPNA6interactor70.7141.149Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
125 KPNB1protein found in more fusions350.301102.669Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
126 KRT40interactor50.6002.389Filament (PF00038, IPR001664): Intermediate filament protein
UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184)
127 KTN1oncoprotein70.3818.822ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PTPS (PF01242, IPR007115): 6-pyruvoyl tetrahydropterin synthase
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Fimbrial_PilY2 (PF14481, IPR029497): Type 4 fimbrial biogenesis protein PilY2
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
128 LATS1suppressor90.33316.790Cas_Cas6 (PF01881, IPR010156): CRISPR associated protein Cas6
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
129 LDHAprotein found in more fusions290.27880.054Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
130 LDHBinteractor240.39955.961Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
131 LGALS1interactor110.43611.338Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
132 LGALS3oncoprotein90.4645.494Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
133 LGALS3BPoncoprotein280.56441.621BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
134 LMNB1interactor160.32514.646Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
135 LRRC47interactor90.3619.334B3_4 (PF03483, IPR005146, SM00873): B3/4 domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
136 LRRK2oncoprotein120.40010.733Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
137 LTBP3oncoprotein21.0000EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
TB (PF00683, IPR017878): TB domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
138 LTBP4interactor21.0000EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
TB (PF00683, IPR017878): TB domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
139 LZTS2suppressor110.34526.601CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
140 MAGI1interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Peptidase_C58 (PF03543, IPR006473): Yersinia/Haemophilus virulence surface antigen
Serglycin (PF04360, IPR007455): Serglycin
WW (PF00397, IPR001202, SM00456): WW domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
PDZ_2 (PF13180, IPR001478): PDZ domain
DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578)
DUF4770 (PF15994, IPR031935): Domain of unknown function (DUF4770)
MAGI_u1 (PF16663): Unstructured region on MAGI
MAGI_u5 (PF16666): Unstructured region on MAGI
141 MAP3K10interactor31.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
142 MAP3K11interactor31.0000APG6 (PF04111, IPR007243): Autophagy protein Apg6
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH3_9 (PF14604, IPR001452): Variant SH3 domain
143 MAP3K4suppressor60.4003.460CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pkinase (PF00069, IPR000719): Protein kinase domain
PLU-1 (PF08429, IPR013637): PLU-1-like protein
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
144 MAPK6oncoprotein70.4674.402Pkinase (PF00069, IPR000719): Protein kinase domain
145 MAPK8oncoprotein140.59016.038DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
146 MARSoncoprotein190.35720.453Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
tRNA-synt_1g (PF09334, IPR015413): tRNA synthetases class I (M)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
147 MCF2Linteractor100PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Spectrin (PF00435, IPR002017): Spectrin repeat
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DUF4771 (PF15995, IPR031936): Domain of unknown function (DUF4771)
148 MCM2oncoprotein630.298467.693AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
149 MCM7protein found in more fusions250.29748.198MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
150 METTL21Binteractor160.6339.745Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
151 METTL21Cinteractor21.0000Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
152 METTL23interactor50.5001.131Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
153 MIPOL1interactor31.0000Bac_globin (PF01152, IPR001486): Bacterial-like globin
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Rho_Binding (PF08912, IPR015008): Rho Binding
IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D
154 MKS1interactor130.5649.596B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein
155 MOB4interactor160.76711.541Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
156 MYConcoprotein560.217609.216HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
157 MYD88oncoprotein60.5002.983Death (PF00531, IPR000488, SM00005): Death domain
TIR (PF01582, IPR000157, SM00255): TIR domain
158 MYH9suppressor300.32996.388IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
159 NCF2interactor100PB1 (PF00564, IPR000270, SM00666): PB1 domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
TPR_16 (PF13432): Tetratricopeptide repeat
160 NEDD1interactor140.74710.473NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
FliM (PF02154, IPR001689): Flagellar motor switch protein FliM
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
161 NEDD4suppressor170.20855.245Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
162 NIPSNAP1interactor130.8461.333NIPSNAP (PF07978, IPR012577): NIPSNAP
163 NOS2interactor220.46728.421FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
164 NOTCH1suppressor180.33138.426Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
165 NOXA1interactor21.0000PB1 (PF00564, IPR000270, SM00666): PB1 domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
166 NSMAFinteractor100.7338.312Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain
GRAM (PF02893, IPR004182, SM00568): GRAM domain
NABP (PF07990, IPR012940): Nucleic acid binding protein NABP
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH
167 NTRK1oncoprotein970.1581989.784I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
168 NXF5interactor31.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
LRR_8 (PF13855, IPR001611): Leucine rich repeat
169 OBSL1interactor450.314156.067BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
170 PAFAH1B2oncoprotein70.4765.011Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family
171 PAK1oncoprotein110.26725.298PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
172 PAK2protein found in more fusions90.39312.817PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
173 PAK3interactor200PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
174 PAK4protein found in more fusions90.39313.905PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
175 PAK5interactor40.6670.500PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
176 PAK6interactor30.6670.500PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
177 PAN2interactor180.40517.871RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
178 PARK2suppressor330.234138.719IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
179 PCinteractor110.5828.792Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
HMGL-like (PF00682, IPR000891): HMGL-like
PYC_OADA (PF02436, IPR003379): Conserved carboxylase domain
180 PDCL3interactor110.7093.959Phosducin (PF02114, IPR024253): Phosducin
UPF0175 (PF03683, IPR005368): Uncharacterised protein family (UPF0175)
181 PDK3interactor91.0000HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
182 PEX14protein found in more fusions130.54511.069HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
183 PIAS3oncoprotein21.0000SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
184 PPP2CAsuppressor400.418136.073Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
185 PPP2CBsuppressor260.57837.708Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
186 PPP2R2Ainteractor190.71910.490WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
187 PPP2R2Binteractor170.7069.350WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
188 PPP2R2Csuppressor130.8462.619WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
189 PPP2R2Dinteractor150.9051.662WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
190 PPP4Cinteractor220.55442.181Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
191 PPP4R2interactor70.3818.201BT1 (PF03092, IPR004324): BT1 family
PPP4R2 (PF09184, IPR015267): PPP4R2
192 PRPF4interactor180.8313.181PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
193 PSMA2interactor190.51619.122Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
194 PSMA3interactor290.45858.001Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
195 PSMA5oncoprotein180.43120.380Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
196 PSMA6interactor200.61112.028Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
197 PTK2protein found in more fusions120.41819.226FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
198 PTK6interactor51.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
199 PTPAsuppressor140.56015.944PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
200 RAD21oncoprotein190.45623.080Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
201 RAF1oncoprotein210.22680.666Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
202 RBMXsuppressor230.35526.747RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
203 RCC2oncoprotein130.53810.914RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
204 RFWD2suppressor110.9780.071Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
IncA (PF04156, IPR007285): IncA protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
WD40_like (PF17005, IPR031544): WD40-like domain
205 RFWD3interactor120.6674.521OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
206 RNF2interactor320.224133.212zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
207 RPN1oncoprotein310.40082.172Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
208 RPS6KB2interactor210.45217.612Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
209 SEC31Binteractor100.7782.416SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
210 SEH1Linteractor80.7501.536WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
211 SEToncoprotein170.33327.298NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
212 SFPQoncoprotein270.31140.100GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
213 SGK2interactor80.7861.577Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
214 SH3BP4protein found in more fusions60.5001.956SH3_2 (PF07653, IPR011511): Variant SH3 domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
215 SH3RF1protein found in more fusions40.6671.000zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
216 SH3RF2interactor50.4005.500SH3_2 (PF07653, IPR011511): Variant SH3 domain
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
SH3_9 (PF14604, IPR001452): Variant SH3 domain
217 SH3RF3interactor21.0000SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
218 SIRT7interactor310.30897.096DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
219 SKIoncoprotein110.4894.913c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
SlyX (PF04102, IPR007236): SlyX
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
220 SNW1protein found in more fusions580.246584.684SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
221 SSSCA1interactor60.7000.758Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
222 STAT3suppressor160.20059.912SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
223 STK24interactor200.63230.366DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
224 STRNoncoprotein170.8533.769CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
225 STRN3interactor170.80116.250Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
226 SUCLG2interactor70.6191.534ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain
Ligase_CoA (PF00549, IPR005811): CoA-ligase
227 SUZ12suppressor190.29436.424DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
228 SYNJ2interactor21.0000DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866)
Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
Syja_N (PF02383, IPR002013): SacI homology domain
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
229 TCP1interactor1040.1821515.542Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
230 TECinteractor41.0000BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
231 TIAM1oncoprotein50.6000.910PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
AAA_22 (PF13401, IPR003593): AAA domain
232 TNFoncoprotein50.8330.667TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
233 TOLLIPinteractor70.6004.833C2 (PF00168, IPR000008, SM00239): C2 domain
CUE (PF02845, IPR003892, SM00546): CUE domain
234 TOP2Aoncoprotein160.34218.476DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Toprim (PF01751, IPR006171, SM00493): Toprim domain
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
235 TP53suppressor580.295408.891DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
236 TRIM28protein found in more fusions390.323139.517ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
237 TRIOoncoprotein40.8330.095T3SS_needle_E (PF08988, IPR012671): Type III secretion system, cytoplasmic E component of needle
GRP (PF07172, IPR010800): Glycine rich protein family
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pap_E4 (PF02711, IPR003861): E4 protein
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Spectrin (PF00435, IPR002017): Spectrin repeat
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
PH_10 (PF15411): Pleckstrin homology domain
SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region
238 TSSK6interactor90.8061.438Pkinase (PF00069, IPR000719): Protein kinase domain
239 TUBA1Cinteractor390.409158.597Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
240 TUBA3Cinteractor90.4445.436Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
241 TUBA3Einteractor70.7141.616Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
242 TUBAL3interactor80.6792.741Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
243 TUBB2Binteractor200.46827.125Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
244 TUBG1protein found in more fusions270.62223.080Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
245 TXNDC9interactor110.47314.950Thioredoxin (PF00085, IPR013766): Thioredoxin
DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619)
246 TYK2interactor130.62114.322Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
247 UBASH3Binteractor220.39044.308His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily
SH3_9 (PF14604, IPR001452): Variant SH3 domain
248 UBCprotein found in more fusions630.244726.011ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
249 UNKLinteractor100Mnd1 (PF03962, IPR005647): Mnd1 family
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
250 UQCRC2oncoprotein240.46449.677Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
251 USP6oncoprotein100RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
252 VARSinteractor170.49315.875Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
Val_tRNA-synt_C (PF10458, IPR019499): Valyl tRNA synthetase tRNA binding arm
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
253 VAV1oncoprotein100.28921.396PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
254 VAV2oncoprotein60.7330.704PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
CotJB (PF12652, IPR024207): CotJB protein
255 VAV3oncoprotein21.0000PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
DUF2326 (PF10088, IPR018760): Uncharacterised protein conserved in bacteria (DUF2326)
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
PH_10 (PF15411): Pleckstrin homology domain
256 VCAM1interactor480.256196.188C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
257 VCPprotein found in more fusions550.353275.555AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
258 VHLsuppressor260.48347.757Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
VHL_C (PF17211): VHL box domain
259 WARSinteractor80.3578.508tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
260 WDR37interactor51.0000DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
261 WDR76interactor100.5563.483WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
SPATIAL (PF15256): SPATIAL
262 WDR82oncoprotein90.7783.627MinC_C (PF03775, IPR005526): Septum formation inhibitor MinC, C-terminal domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
263 WDR83interactor130.6288.428WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
264 WDR92interactor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Itfg2 (PF15907, IPR031793): Integrin-alpha FG-GAP repeat-containing protein 2
265 WRAP53oncoprotein100.9780.222WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
266 XIAPinteractor100.47210.846BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
267 XRCC3oncoprotein100.35610.237Rad51 (PF08423, IPR013632): Rad51
RNA_pol_A_CTD (PF03118, IPR011260): Bacterial RNA polymerase, alpha chain C terminal domain
268 XRCC6oncoprotein300.254114.516Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ARHGAP1interactorRhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
2 ARHGAP15interactorPH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
3 ARHGAP17interactorBAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
4 ARHGAP31interactorRhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
5 ARHGAP44interactorBAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
6 ARHGDIAinteractorRho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
7 ARHGDIBinteractorRho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
8 ARHGEF25interactorPH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PH_10 (PF15411): Pleckstrin homology domain
SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region
9 ARHGEF7interactorBorrelia_lipo_1 (PF05714, IPR008421): Borrelia burgdorferi virulent strain associated lipoprotein
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7
RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7
10 ARL2BPinteractorARL2_Bind_BART (PF11527, IPR023379): The ARF-like 2 binding protein BART
11 C17orf102interactorNA
12 CAV1suppressorCaveolin (PF01146, IPR001612): Caveolin
13 CCT3parental proteinCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
14 CDC23interactorANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23
DUF772 (PF05598, IPR008490): Transposase domain (DUF772)
Menin (PF05053, IPR007747): Menin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
15 CDC42SE1interactorPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
16 CDC42SE2interactorPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
17 CFAP36interactorDUF1068 (PF06364, IPR010471): Protein of unknown function (DUF1068)
ARL2_Bind_BART (PF11527, IPR023379): The ARF-like 2 binding protein BART
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
18 CLNS1AinteractorVoldacs (PF03517): Regulator of volume decrease after cellular swelling
19 COG5interactorAceK (PF06315, IPR010452): Isocitrate dehydrogenase kinase/phosphatase (AceK)
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
COG5 (PF10392, IPR019465): Golgi transport complex subunit 5
DUF3800 (PF12686, IPR024524): Protein of unknown function (DUF3800)
20 COX3interactorNA
21 CSN2interactorCasein (PF00363, IPR001588): Casein
22 DCAF7interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
23 DDB2suppressorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
24 DIAPH3interactorDrf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
POX (PF07526, IPR006563, SM00574): Associated with HOX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
25 DOCK8interactorDHR-2 (PF06920, IPR010703): Dock homology region 2
DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
DOCK_N (PF16172, IPR032376): DOCK N-terminus
26 EIF2B2interactorIF-2B (PF01008, IPR000649): Initiation factor 2 subunit family
27 FHOD1interactorMito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
28 FLNBoncoproteinCH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
29 GTF2IinteractorGTF2I (PF02946, IPR004212): GTF2I-like repeat
30 HPS4interactorNA
31 HSPE1interactorCpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
32 LIMA1suppressorLIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
33 MCM3APinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAC3_GANP (PF03399, IPR005062): SAC3/GANP family
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2
NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein
MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP
34 METTL18interactorMethyltransf_23 (PF13489): Methyltransferase domain
35 MTNR1Ainteractor7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
TctB (PF07331, IPR009936): Tripartite tricarboxylate transporter TctB family
36 NCKAP1interactorNckap1 (PF09735, IPR019137): Membrane-associated apoptosis protein
37 NME1suppressorNDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
38 OPHN1interactorPH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
BAR_3 (PF16746): BAR domain of APPL family
39 PACRGsuppressorParcG (PF10274, IPR019399): Parkin co-regulated protein
40 PARD6AinteractorPB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
41 PARD6BinteractorPB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
42 PARD6GinteractorPB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
43 PEX7interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
44 PKMoncoproteinPK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
45 PLEKHG2oncoproteinPH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
46 PNPLA1interactorPatatin (PF01734, IPR002641): Patatin-like phospholipase
47 POC1AinteractorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
48 PRKYinteractorNA
49 PRMT6interactorMethyltransf_25 (PF13649): Methyltransferase domain
50 PSAT1interactorAminotran_5 (PF00266, IPR000192): Aminotransferase class-V
51 PSMC2interactorAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
52 RAB2AoncoproteinRas (PF00071, IPR001806, SM00173): Ras family
53 RAC1parental proteinRas (PF00071, IPR001806, SM00173): Ras family
54 RALBP1interactorDDHD (PF02862, IPR004177, SM01127): DDHD domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SlyX (PF04102, IPR007236): SlyX
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1
55 RAP1GDS1oncoproteinArm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
56 RELBoncoproteinRHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
RelB_leu_zip (PF16180, IPR032399): RelB leucine zipper
RelB_transactiv (PF16181, IPR032400): RelB transactivation domain
57 RGL2interactorRA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
58 RHOBsuppressorRas (PF00071, IPR001806, SM00173): Ras family
59 RHOConcoproteinRas (PF00071, IPR001806, SM00173): Ras family
60 RPL3interactorRibosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
61 SLC25A3interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
62 STOMinteractorBand_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
63 TALDO1interactorTAL_FSA (PF00923, IPR001585): Transaldolase/Fructose-6-phosphate aldolase
64 TOM1oncoproteinGAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
65 TSSC1suppressorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
66 TTLL3oncoproteinTTL (PF03133, IPR004344): Tubulin-tyrosine ligase family
67 USH1CinteractorCemA (PF03040, IPR004282): CemA family
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
Saw1 (PF11561, IPR021624): Single strand annealing-weakened 1
DUF3393 (PF11873, IPR024570): Domain of unknown function (DUF3393)
DUF3567 (PF12091, IPR021951): Protein of unknown function (DUF3567)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
68 VWFinteractorAntistasin (PF02822, IPR004094): Antistasin family
C8 (PF08742, IPR014853, SM00832): C8 domain
Metallothio_5 (PF02067, IPR000966): Metallothionein family 5
Pacifastin_I (PF05375, IPR008037): Pacifastin inhibitor (LCMII)
TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
VWD (PF00094, IPR001846, SM00216): von Willebrand factor type D domain
VWA_N2 (PF16164, IPR032361): VWA N-terminal
69 WASoncoproteinCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
PRIMA1 (PF16101): Proline-rich membrane anchor 1
70 WASF1interactorMito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
WH2 (PF02205, IPR003124, SM00246): WH2 motif

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