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Powered by Cytoscape Web for: CA450349 is the fusion of parental proteins NDUFS3 (from a repository: Wed Dec 28 20:40:14 2016)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)136
The number (and %) of the onco-proteins20 (14.71 %)
The number (and %) of the tumor suppressors5 (3.68 %)
Total number of binary PPIs (saturation %)1216 (13.25 %)
The number (and %) of affected PPIs135 (11.10 %)
The number of possible different fusions13
PPI diameter2
PPI radius1
The average degree of PPI17.324
Assortativity coefficient-0.1792
The network average Clustering coefficient0.431
The number (and %) of a zero Clustering coefficients3 (2.21 %)
The number (and %) of a zero Betweenness Centrality5 (3.68 %)


List of the fusions

PPI for parental proteins: NDUFS3 All fusions
: CA450349;
Proteins found in more fusions CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); IMMT (see 4 fusions); UBC (see 1 fusions); NDUFAF4 (see 1 fusions); NDUFAF8 (see 1 fusions); ILK (see 1 fusions); SFPQ (see 6 fusions); HUWE1 (see 2 fusions); SQSTM1 (see 5 fusions); EGFR (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 CA450349chimera1350.1159087.694Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
2 ACAD9interactor150.61012.999Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
3 ACOT13interactor50.5002.3334HBT (PF03061, IPR006683): Thioesterase superfamily
DUF4442 (PF14539, IPR027961): Domain of unknown function (DUF4442)
4 ADRB2interactor160.23835.9137tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
5 ATP1B1interactor140.57110.869Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
6 ATP1B3interactor120.5767.548Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
7 ATP5C1interactor330.258171.060ATP-synt (PF00231, IPR000131): ATP synthase
ACT_4 (PF13291, IPR002912): ACT domain
8 ATP5F1interactor300.320127.947Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
9 ATP5Hinteractor160.43319.345Mt_ATP-synt_D (PF05873, IPR008689): ATP synthase D chain, mitochondrial (ATP5H)
10 ATP5Iinteractor110.43618.346ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
11 ATP5Jinteractor130.43620.102ATP-synt_F6 (PF05511, IPR008387): Mitochondrial ATP synthase coupling factor 6
12 ATP5Ointeractor260.29899.495OSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit
13 C1QBPinteractor300.184196.990MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
14 CHCHD10interactor230.19063.561CHCH (PF06747, IPR010625): CHCH domain
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
15 CHCHD2interactor250.38066.192CHCH (PF06747, IPR010625): CHCH domain
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
16 CISD3interactor340.152198.942zf-CDGSH (PF09360, IPR018967, SM00704): Iron-binding zinc finger CDGSH type
MOLO1 (PF17175): Modulator of levamisole receptor-1
17 CLPBinteractor110.2558.969AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
Torsin (PF06309, IPR010448): Torsin
ClpB_D2-small (PF10431, IPR019489, SM01086): C-terminal, D2-small domain, of ClpB protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
AAA_33 (PF13671): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
18 CLPXinteractor110.4556.012AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
ClpB_D2-small (PF10431, IPR019489, SM01086): C-terminal, D2-small domain, of ClpB protein
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
Sigma54_activ_2 (PF14532, IPR002078): Sigma-54 interaction domain
19 COQ8Ainteractor140.42316.540ABC1 (PF03109, IPR004147): ABC1 family
CbtA (PF09490, IPR012666): Probable cobalt transporter subunit (CbtA)
20 COQ9interactor410.203312.742COQ9 (PF08511, IPR013718): COQ9
21 COX6A1interactor80.4642.302COX6A (PF02046, IPR001349): Cytochrome c oxidase subunit VIa
22 COX6Concoprotein70.4292.011COX6C (PF02937, IPR004204): Cytochrome c oxidase subunit VIc
23 COX7A2interactor60.4000.975COX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
24 CRY1interactor70.5332.025DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
25 CUL3protein found in more fusions230.30367.052Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
26 CUL7protein found in more fusions160.23835.227ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
27 CYB5R3interactor120.37916.970FAD_binding_6 (PF00970, IPR008333): Oxidoreductase FAD-binding domain
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
28 CYC1interactor240.30890.294Cytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family
29 DHRS4interactor160.31436.075adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
30 ECH1interactor160.25833.448ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
31 ECI2interactor70.4006.367ACBP (PF00887, IPR000582): Acyl CoA binding protein
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
32 ECSITinteractor220.41957.752ECSIT (PF06239, IPR010418): Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C (PF14784, IPR029342): C-terminal domain of the ECSIT protein
33 EGFRoncoprotein230.30780.848Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
34 ETFAinteractor80.5366.372ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain
ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain
35 FN1oncoprotein190.27570.041fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
36 GFM1interactor40.5000.968EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
37 GOLT1Binteractor330.375124.551Got1 (PF04178, IPR007305): Got1/Sft2-like family
38 HTRA2suppressor50.5001.022Peptidase_S32 (PF05579, IPR008760): Equine arteritis virus serine endopeptidase S32
PDZ_2 (PF13180, IPR001478): PDZ domain
Trypsin_2 (PF13365): Trypsin-like peptidase domain
39 HUWE1oncoprotein190.34650.785BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
40 ILKsuppressor120.34519.862Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
41 ILVBLinteractor120.36416.973TPP_enzyme_C (PF02775, IPR011766): Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
TPP_enzyme_N (PF02776, IPR012001): Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
42 IMMTprotein found in more fusions220.25768.056Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
43 ITGA4interactor120.50913.011FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
44 LMAN2interactor50.8000.273Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Tad (PF13400, IPR028087): Putative Flp pilus-assembly TadE/G-like
45 MOV10interactor280.206155.562AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
46 MRPL13interactor100.31117.934Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
47 MRPL16interactor40.8330.500Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
48 MRPL22interactor70.4764.571Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
49 MRPL3interactor60.6672.333Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
50 MRPL46interactor60.6004.262NUDIX (PF00293, IPR000086): NUDIX domain
MRP-L46 (PF11788, IPR021757): 39S mitochondrial ribosomal protein L46
51 MRPL53interactor30.6670.667MRP_L53 (PF10780, IPR019716): 39S ribosomal protein L53/MRP-L53
52 MRPL58interactor400.181351.634RF-1 (PF00472, IPR000352): RF-1 domain
53 MRPS10interactor80.3935.826Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
54 MTHFSinteractor1005-FTHF_cyc-lig (PF01812, IPR002698): 5-formyltetrahydrofolate cyclo-ligase family
55 MYConcoprotein230.29492.861HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
56 NDUFA10interactor160.45029.975dNK (PF01712, IPR002624): Deoxynucleoside kinase
57 NDUFA11interactor280.45871.1477kD_coat (PF02495, IPR003411): 7kD viral coat protein
Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
58 NDUFA12interactor430.348228.416NDUFA12 (PF05071, IPR007763): NADH ubiquinone oxidoreductase subunit NDUFA12
59 NDUFA13interactor270.42579.689GRIM-19 (PF06212, IPR009346): GRIM-19 protein
60 NDUFA2interactor250.36789.104L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
61 NDUFA3interactor41.0000NADHdh_A3 (PF14987, IPR026626): NADH dehydrogenase 1 alpha subcomplex subunit 3
62 NDUFA5interactor240.25090.946ETC_C1_NDUFA5 (PF04716, IPR006806): ETC complex I subunit conserved region
63 NDUFA6interactor80.8570.658Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)
64 NDUFA7interactor100.6449.055CI-B14_5a (PF07347, IPR009947): NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
65 NDUFA8interactor390.327217.106CHCH (PF06747, IPR010625): CHCH domain
Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191
Cdd1 (PF11731, IPR021725): Pathogenicity locus
66 NDUFA9interactor440.339250.584Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
67 NDUFAB1interactor60.4006.400MinE (PF03776, IPR005527): Septum formation topological specificity factor MinE
PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site
68 NDUFAF1interactor130.7055.602CIA30 (PF08547, IPR013857): Complex I intermediate-associated protein 30 (CIA30)
69 NDUFAF3interactor220.46850.015DUF498 (PF04430, IPR007523): Protein of unknown function (DUF498/DUF598)
70 NDUFAF4protein found in more fusions250.33096.135UPF0240 (PF06784, IPR009622): Uncharacterised protein family (UPF0240)
71 NDUFAF5interactor100.41711.459Methyltransf_11 (PF08241, IPR013216): Methyltransferase domain
72 NDUFAF8protein found in more fusions190.28838.831ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
73 NDUFB1interactor80.5712.901NADH_oxidored (PF08040, IPR012575): MNLL subunit
74 NDUFB10interactor200.47433.947NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10
75 NDUFB11interactor120.6066.499ESSS (PF10183, IPR019329): ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
76 NDUFB3interactor70.7141.151NDUF_B12 (PF08122, IPR012576): NADH-ubiquinone oxidoreductase B12 subunit family
77 NDUFB4interactor130.8461.912NDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
78 NDUFB5interactor160.6179.248NDUF_B5 (PF09781, IPR019173): NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
79 NDUFB6interactor80.8570.459NDUF_B6 (PF09782, IPR019174): NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
80 NDUFB7interactor150.57110.808DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
NDUF_B7 (PF05676, IPR008698): NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
OrfB_IS605 (PF01385, IPR001959): Probable transposase
81 NDUFB8interactor190.50328.773NDUF_B8 (PF05821, IPR008699): NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
82 NDUFB9interactor190.46228.328Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)
83 NDUFS1interactor390.350199.647NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
Molybdopterin (PF00384, IPR006656): Molybdopterin oxidoreductase
NADH-G_4Fe-4S_3 (PF10588, IPR019574, SM00929): NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
Fer2_4 (PF13510): 2Fe-2S iron-sulfur cluster binding domain
84 NDUFS2interactor400.326224.378Complex1_49kDa (PF00346, IPR001135): Respiratory-chain NADH dehydrogenase, 49 Kd subunit
NiFeSe_Hases (PF00374, IPR001501): Nickel-dependent hydrogenase
85 NDUFS4interactor300.49764.773ETC_C1_NDUFA4 (PF04800, IPR006885): ETC complex I subunit conserved region
86 NDUFS5interactor360.422120.694Ndufs5 (PF10200, IPR019342): NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
87 NDUFS6interactor210.66221.251Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
zf-CHCC (PF10276, IPR019401, SM00400): Zinc-finger domain
88 NDUFS7interactor270.52963.698Oxidored_q6 (PF01058, IPR006137): NADH ubiquinone oxidoreductase, 20 Kd subunit
89 NDUFS8interactor290.43889.250Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
Fer4_16 (PF13484): 4Fe-4S double cluster binding domain
90 NDUFV1interactor340.421148.912Complex1_51K (PF01512, IPR011538): Respiratory-chain NADH dehydrogenase 51 Kd subunit
NADH_4Fe-4S (PF10589, IPR019575, SM00928): NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
SLBB (PF10531, IPR019554): SLBB domain
91 NDUFV2interactor260.52361.1392Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin
92 NDUFV3interactor160.62514.836DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
NDUFV3 (PF15880, IPR026193): NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
93 NIPSNAP1interactor140.33020.200NIPSNAP (PF07978, IPR012577): NIPSNAP
94 NONOoncoprotein120.45513.208GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PAS_7 (PF12860): PAS fold
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
95 NPHP1interactor31.0000SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FAM176 (PF14851): FAM176 family
Speriolin_N (PF15058, IPR029385): Speriolin N terminus
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
96 NPLOC4interactor60.6671.455NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
97 NTRK1oncoprotein400.186348.249I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
98 NXF1interactor270.185146.244NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
99 OCIAD1interactor290.164143.406OCIA (PF07051, IPR009764): Ovarian carcinoma immunoreactive antigen (OCIA)
100 OXCT1interactor80.6192.304CoA_trans (PF01144, IPR004165, SM00882): Coenzyme A transferase
101 PARK2suppressor190.25559.635IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
102 PARK7suppressor70.5334.250DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
103 PITRM1interactor70.4293.933M16C_assoc (PF08367, IPR013578): Peptidase M16C associated
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
104 PMPCAinteractor100.5783.634Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
105 PMPCBinteractor150.37121.434Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
106 POLDIP2interactor170.27930.946DUF525 (PF04379, IPR007474): Protein of unknown function (DUF525)
YccV-like (PF08755, IPR011722, SM00992): Hemimethylated DNA-binding protein YccV like
107 POU5F1oncoprotein80.5244.599Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
108 PROSCinteractor100Ala_racemase_N (PF01168, IPR001608): Alanine racemase, N-terminal domain
109 PTPMT1interactor260.25780.333DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
110 SAMM50interactor90.5008.248Bac_surface_Ag (PF01103, IPR000184): Surface antigen
POTRA (PF07244, IPR010827): Surface antigen variable number repeat
111 SCO1interactor40.5000.689SCO1-SenC (PF02630, IPR003782): SCO1/SenC
112 SDHAsuppressor250.320102.867FAD_binding_2 (PF00890, IPR003953): FAD binding domain
Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term
113 SFPQoncoprotein180.39037.589GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
114 SFXN3interactor90.4448.847Mtc (PF03820, IPR004686): Tricarboxylate carrier
115 SHMT2interactor150.30532.251SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
116 SLC16A1oncoprotein90.3068.081MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
117 SLC3A2interactor70.4295.653Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain
DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459)
SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus
118 SQSTM1oncoprotein150.46221.932PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
119 SSBP1interactor130.42415.635SSB (PF00436, IPR000424): Single-strand binding protein family
120 STOML2oncoprotein160.31720.526Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4769 (PF15992, IPR031934): Domain of unknown function (DUF4769)
Band_7_C (PF16200, IPR032435): C-terminal region of band_7
121 SURF1interactor110.45513.256SURF1 (PF02104, IPR002994): SURF1 family
122 TCTN3interactor140.40720.419DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
123 TIMM44interactor120.28822.769Tim44 (PF04280, IPR007379, SM00978): Tim44-like domain
DUF4211 (PF13926, IPR025451): Domain of unknown function (DUF4211)
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
RecG_N (PF17190): RecG N-terminal helical domain
124 TIMMDC1interactor290.392113.138Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
125 TMEM126Binteractor70.9050.293TMEM126 (PF07114, IPR009801): Transmembrane protein 126
126 TMEM14Cinteractor100Tmemb_14 (PF03647, IPR005349): Transmembrane proteins 14C
127 TMEM17interactor50.4003.519Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
128 TSFMinteractor30.6670.667EF_TS (PF00889, IPR014039): Elongation factor TS
129 UBCprotein found in more fusions270.323106.358ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
130 UBR2interactor30.6670.222ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS
zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
131 UQCR10interactor70.5242.684UCR_UQCRX_QCR9 (PF05365, IPR008027): Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like
132 UQCRBinteractor210.44340.310UCR_14kD (PF02271, IPR003197): Ubiquinol-cytochrome C reductase complex 14kD subunit
133 UQCRC2oncoprotein260.35483.989Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
134 UQCRFS1interactor230.36866.453Rieske (PF00355, IPR017941): Rieske [2Fe-2S] domain
Ubiq-Cytc-red_N (PF09165, IPR015248): Ubiquinol-cytochrome c reductase 8 kDa, N-terminal
UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region
135 UQCRQinteractor190.32245.368UcrQ (PF02939, IPR004205): UcrQ family
136 VCAM1interactor100.5567.678C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 BCKDHAinteractorE1_dh (PF00676, IPR001017): Dehydrogenase E1 component
2 C15orf48interactorB12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
3 C2orf47interactorTim44 (PF04280, IPR007379, SM00978): Tim44-like domain
4 CBR3interactoradh_short (PF00106, IPR002198): short chain dehydrogenase
5 CPT2interactorCarn_acyltransf (PF00755, IPR000542): Choline/Carnitine o-acyltransferase
6 GLRX5interactorGlutaredoxin (PF00462, IPR002109): Glutaredoxin
7 GZMAinteractorTrypsin (PF00089, IPR001254, SM00020): Trypsin
8 MT-ND5interactorNADH5_C (PF06455, IPR010934): NADH dehydrogenase subunit 5 C-terminus
Proton_antipo_M (PF00361, IPR001750): Proton-conducting membrane transporter
Proton_antipo_N (PF00662, IPR001516): NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
9 MT-ND6interactorCD20 (PF04103, IPR007237): CD20-like family
Oxidored_q3 (PF00499, IPR001457): NADH-ubiquinone/plastoquinone oxidoreductase chain 6
10 MTCH2interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
11 NANOGinteractorHomeobox (PF00046, IPR001356, SM00389): Homeobox domain
12 ND1interactorNA
13 ND4interactorNA
14 NDUFA4interactorB12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
15 NDUFS3parental proteinComplex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
16 RASL10BsuppressorRas (PF00071, IPR001806, SM00173): Ras family

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