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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: CA436787 is the fusion of parental proteins AEBP1, PRAF2 (from a repository: Wed Feb 21 09:56:34 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)2
The number (and %) of the onco-proteins2 (100.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)2 (200.00 %)
The number (and %) of affected PPIs1 (50.00 %)
The number of possible different fusions2
PPI diameter1
PPI radius1
The average degree of PPI1.000
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients2 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (100.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: AEBP1,PRAF2 All fusions
: CA436787;
Proteins found in more fusions GRB2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CA436787chimera100NESP55 (PF06390, IPR009434): Neuroendocrine-specific golgi protein P55 (NESP55)
Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
2 GRB2oncoprotein200SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AEBP1parental proteinGAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
2 DLK1suppressorEGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
3 FAM63BinteractorDUF544 (PF04424, IPR007518): Protein of unknown function (DUF544)
Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
CCDC50_N (PF15295, IPR029311): Coiled-coil domain-containing protein 50 N-terminus
4 HMOX2interactorHeme_oxygenase (PF01126, IPR016053): Heme oxygenase
5 LPAR1oncoprotein7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
6 PRAF2parental proteinPRA1 (PF03208, IPR004895): PRA1 family protein
7 RP2interactorNDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
TBCC (PF07986, IPR012945): Tubulin binding cofactor C
8 RTN4suppressorCENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Reticulon (PF02453, IPR003388): Reticulon
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
9 TCTN2interactorDUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
10 TCTN3interactorDUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
11 TNFRSF10BsuppressorDeath (PF00531, IPR000488, SM00005): Death domain
RskA (PF10099, IPR018764): Anti-sigma-K factor rskA
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
12 TSPAN17interactorTetraspannin (PF00335, IPR018499): Tetraspanin family
13 TSPAN5interactorTetraspannin (PF00335, IPR018499): Tetraspanin family

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