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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: CA425105 is the fusion of parental proteins RPLP2, CALR (from a repository: Wed Dec 7 05:51:18 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)225
The number (and %) of the onco-proteins76 (33.78 %)
The number (and %) of the tumor suppressors19 (8.44 %)
Total number of binary PPIs (saturation %)5139 (20.39 %)
The number (and %) of affected PPIs224 (4.36 %)
The number of possible different fusions44
PPI diameter2
PPI radius1
The average degree of PPI45.049
Assortativity coefficient0.0543
The network average Clustering coefficient0.590
The number (and %) of a zero Clustering coefficients4 (1.78 %)
The number (and %) of a zero Betweenness Centrality11 (4.89 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: RPLP2,CALR All fusions
: CA425105;
Proteins found in more fusions GRK5 (see 4 fusions); U2AF2 (see 2 fusions); HNRNPU/RPL24 (see 1 fusions); CUL4A (see 4 fusions); RPS24/RPS23 (see 1 fusions); RPS24/RPS27 (see 1 fusions); RPL27/RPS6 (see 1 fusions); HUWE1 (see 2 fusions); RPL38/RPL3 (see 1 fusions); EZR (see 2 fusions); HSPB1 (see 4 fusions); RPS19/RPS14 (see 1 fusions); TUBG1 (see 1 fusions); NTRK1/RPL7A (see 1 fusions); PPME1 (see 1 fusions); CUL3 (see 1 fusions); MRPL12 (see 1 fusions); COPS5 (see 1 fusions); UBC (see 1 fusions); TP53 (see 3 fusions); ELF3 (see 2 fusions); CD40 (see 2 fusions); FN1/RPL6 (see 1 fusions); CUL1 (see 3 fusions); EWSR1 (see 2 fusions); GANAB/PRKCSH (see 1 fusions); RPS5/RPL14 (see 1 fusions); PCNA (see 1 fusions); TPD52L2 (see 2 fusions); RPA1 (see 1 fusions); SUZ12 (see 2 fusions); APP (see 4 fusions); VCP (see 4 fusions); TKT (see 5 fusions); HSP90AB1 (see 1 fusions); SRPK2 (see 1 fusions); CUL7 (see 2 fusions); SMARCB1 (see 12 fusions); NR3C1 (see 8 fusions); PABPC1 (see 2 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); B2M (see 10 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CA425105chimera2240.19419921.796Calreticulin (PF00262, IPR001580): Calreticulin family
IncA (PF04156, IPR007285): IncA protein
OspD (PF03207, IPR004894): Borrelia outer surface protein D (OspD)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
2 AARSD1interactor130.51320.321tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
3 ACTR2interactor230.36065.615Actin (PF00022, IPR004000, SM00268): Actin
4 ANP32Boncoprotein170.31641.384FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
SDA1 (PF05285, IPR007949): SDA1
LRR_9 (PF14580): Leucine-rich repeat
5 APOBinteractor60.9000.087DUF1081 (PF06448, IPR009454): Domain of Unknown Function (DUF1081)
DUF1943 (PF09172, IPR015255, SM01169): Domain of unknown function (DUF1943)
Phage_holin_6_1 (PF09682, IPR010026): Bacteriophage holin of superfamily 6 (Holin_LLH)
Vitellogenin_N (PF01347, IPR001747, SM00638): Lipoprotein amino terminal region
DUF2807 (PF10988, IPR021255): Putative auto-transporter adhesin, head GIN domain
ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
6 APPprotein found in more fusions520.321403.408APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
7 ARoncoprotein160.29534.246Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
8 ARPC1Ainteractor140.52723.207WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
9 ARPC1Binteractor160.35831.870WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
10 ARPC3interactor140.35227.813P21-Arc (PF04062, IPR007204): ARP2/3 complex ARPC3 (21 kDa) subunit
11 ARPC5interactor120.50017.229P16-Arc (PF04699, IPR006789): ARP2/3 complex 16 kDa subunit (p16-Arc)
12 ARRB2interactor520.55786.055Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
13 ATF2oncoprotein190.35931.740bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
14 ATP1B3interactor130.5267.530Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
15 ATP5Binteractor260.50529.038AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
16 AURKAoncoprotein390.444144.199Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
17 B2Moncoprotein70.6005.333C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
18 CALUinteractor340.246230.273EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
19 CAND1interactor990.593326.894Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
20 CANXinteractor390.243346.383Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
21 CD1Dinteractor30.6671.000Kelch_2 (PF07646, IPR011498): Kelch motif
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
MHC_I_3 (PF16497, IPR011161): MHC-I family domain
22 CD40protein found in more fusions200Glycophorin_A (PF01102, IPR001195): Glycophorin A
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
23 CD81interactor390.76025.459Tetraspannin (PF00335, IPR018499): Tetraspanin family
24 CDK2suppressor850.462507.714Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
25 CEP250interactor590.71581.418ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
26 CEP57interactor240.65922.767Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
27 CLN5interactor50.8000.400CLN5 (PF15014, IPR026138): Ceroid-lipofuscinosis neuronal protein 5
28 CNDP2suppressor60.6003.952Peptidase_M20 (PF01546, IPR002933): Peptidase family M20/M25/M40
29 CNTRLoncoprotein70.2869.733APG6 (PF04111, IPR007243): Autophagy protein Apg6
BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fez1 (PF06818): Fez1
Laminin_II (PF06009, IPR010307): Laminin Domain II
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
TMPIT (PF07851, IPR012926): TMPIT-like protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
LRR_9 (PF14580): Leucine-rich repeat
30 COPS5protein found in more fusions960.559487.901JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
31 COPS6interactor410.571106.595DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
32 COX5Binteractor30.6670.222COX5B (PF01215, IPR002124): Cytochrome c oxidase subunit Vb
33 CTNNB1oncoprotein240.38049.735Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
34 CUL1suppressor990.547397.990Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
35 CUL2suppressor710.592243.232Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
36 CUL3protein found in more fusions1120.445896.829Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
37 CUL4Aprotein found in more fusions410.56944.809Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
38 CUL4Boncoprotein660.596109.804Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
39 CUL5suppressor740.630132.144Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
40 CUL7protein found in more fusions750.403494.001ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
41 DCUN1D1interactor310.7468.855Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
42 DDX24interactor220.8531.697DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tti2 (PF10521, IPR018870): Tti2 family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
43 EEF2interactor580.511230.300EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
44 EEF2Kinteractor70.4295.099Alpha_kinase (PF02816, IPR004166, SM00811): Alpha-kinase family
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
45 EGFRoncoprotein470.248278.004Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
46 ELAVL1oncoprotein460.262317.886RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
47 ELF3oncoprotein60.5001.937AT_hook (PF02178, IPR017956, SM00384): AT hook motif
Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
48 ENO1oncoprotein340.38795.047Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
49 ENO2interactor160.52518.845Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
50 ENO3interactor60.6671.425Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
51 EPB41suppressor40.6670.0694_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
SAB (PF04382, IPR007477): SAB domain
52 EWSR1oncoprotein490.406167.686RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
53 EZRprotein found in more fusions250.36662.125DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
54 F5interactor31.0000Cu-oxidase_2 (PF07731, IPR011706): Multicopper oxidase
Cu-oxidase_3 (PF07732, IPR011707): Multicopper oxidase
LSPR (PF06049, IPR009271): Coagulation Factor V LSPD Repeat
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
DUF4672 (PF15716, IPR031445): Domain of unknown function (DUF4672)
55 F8interactor40.6671.667Cu-oxidase (PF00394, IPR001117): Multicopper oxidase
Cu-oxidase_2 (PF07731, IPR011706): Multicopper oxidase
Cu-oxidase_3 (PF07732, IPR011707): Multicopper oxidase
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
56 FBXO6interactor510.315337.130FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
57 FGBinteractor21.0000Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
58 FN1oncoprotein920.497660.205fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
59 GANABsuppressor230.36869.396Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
DUF5110 (PF17137): Domain of unknown function (DUF5110)
60 GRK5protein found in more fusions100.6111.147Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
61 H2AFXsuppressor250.36343.823Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
62 HLA-Aoncoprotein100.44418.902DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
63 HLA-Einteractor31.0000MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
AA_permease_C (PF13906, IPR029485): C-terminus of AA_permease
64 HNRNPA1interactor650.390241.754RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
65 HNRNPA3oncoprotein350.45237.031IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
66 HNRNPUprotein found in more fusions1010.580337.020CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
67 HSP90AB1oncoprotein630.400273.041HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
68 HSP90B1suppressor370.356158.247CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
69 HSPB1oncoprotein310.366108.771HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
70 HUWE1oncoprotein630.545156.567BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
71 ICAM1oncoprotein490.72858.784Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
72 IGSF8oncoprotein490.76440.501V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
73 INHAoncoprotein21.0000TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
74 ITGA3interactor30.6670.250FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
FG-GAP_2 (PF14312, IPR013517): FG-GAP repeat
MLANA (PF14991, IPR029242): Protein melan-A
75 KCNH2interactor50.8000.315Ion_trans (PF00520, IPR005821): Ion transport protein
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
PAS_9 (PF13426, IPR000014): PAS domain
76 KRASoncoprotein130.34822.705Ras (PF00071, IPR001806, SM00173): Ras family
77 KRT17interactor60.6670.631DUF1798 (PF08807, IPR014913): Bacterial domain of unknown function (DUF1798)
Filament (PF00038, IPR001664): Intermediate filament protein
78 LGR4interactor100.5004.0797tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
79 LPLinteractor70.5331.942Lipase (PF00151, IPR013818): Lipase
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
80 LPPoncoprotein100.35613.615LIM (PF00412, IPR001781, SM00132): LIM domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
81 LRIF1interactor60.5001.952LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
82 LRP1interactor90.44413.982EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region
TadE (PF07811, IPR012495): TadE-like protein
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050)
83 MAPK6oncoprotein120.25517.446Pkinase (PF00069, IPR000719): Protein kinase domain
84 MAPK8oncoprotein120.5276.474DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
85 MAPRE3interactor30.6670.500CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
86 MATR3interactor290.45838.073DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FAM60A (PF15396, IPR026065): Protein Family FAM60A
87 MBL2interactor100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
88 MCM2oncoprotein920.480395.887AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
89 MRPL12protein found in more fusions150.7697.668Ribosomal_L12 (PF00542, IPR013823): Ribosomal protein L7/L12 C-terminal domain
Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain
90 MRPS21interactor60.8000.131Ribosomal_S21 (PF01165, IPR001911): Ribosomal protein S21
91 MSNoncoprotein250.39554.403DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
92 MTNR1Ainteractor30.6670.5007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
TctB (PF07331, IPR009936): Tripartite tricarboxylate transporter TctB family
93 NACA2interactor120.5457.196NAC (PF01849, IPR002715): NAC domain
94 NANSinteractor70.6193.723NeuB (PF03102, IPR013132): NeuB family
SAF (PF08666, IPR013974, SM00858): SAF domain
95 NEDD8interactor450.63347.269ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
96 NKX2-1oncoprotein100DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF4719 (PF15843, IPR031696): Domain of unknown function (DUF4719)
97 NPEPPSinteractor100.4227.890Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain
98 NR3C1protein found in more fusions110.37812.257GCR (PF02155, IPR001409): Glucocorticoid receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
99 NSUN2interactor190.39240.973Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
100 NTMinteractor31.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain
Ig_3 (PF13927): Immunoglobulin domain
101 NTRK1oncoprotein910.326900.861I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
102 P4HBinteractor450.320229.107Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
103 PA2G4interactor270.55849.020Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
TraC (PF07820, IPR012930): TraC-like protein
104 PABPC1oncoprotein640.57191.630RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
105 PAN2interactor710.726114.312RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
106 PARK2suppressor430.43188.390IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
107 PCNAoncoprotein290.41840.717PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
108 PDIA3interactor260.234166.626Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
109 PFDN5interactor60.6671.798Prefoldin (PF02996, IPR004127): Prefoldin subunit
UPF0693 (PF16088, IPR032143): UPF0693 family
110 PLATinteractor30.6670.667EGF (PF00008, IPR000742, SM00181): EGF-like domain
fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
Kringle (PF00051, IPR000001): Kringle domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
111 PLP1interactor100Myelin_PLP (PF01275, IPR001614, SM00002): Myelin proteolipid protein (PLP or lipophilin)
112 PPME1protein found in more fusions140.42314.597Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
113 PRF1oncoprotein31.0000C2 (PF00168, IPR000008, SM00239): C2 domain
MACPF (PF01823, IPR020864, SM00457): MAC/Perforin domain
114 PRKACAinteractor130.42324.794Pkinase (PF00069, IPR000719): Protein kinase domain
115 PRKCSHprotein found in more fusions150.45724.120CDC45 (PF02724, IPR003874): CDC45-like protein
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
PRKCSH-like (PF12999, IPR028146): Glucosidase II beta subunit-like
PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
EF-hand_5 (PF13202, IPR002048): EF hand
116 PSMA3interactor220.50525.293Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
117 PTENsuppressor340.64035.691DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
118 PTGES3interactor230.34658.535CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
119 RCN1interactor200.37944.937EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
120 RDXinteractor140.52712.543ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
121 RNF2interactor670.491298.774zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
122 RPA1suppressor470.456169.001Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
123 RPA3interactor340.53861.935Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
124 RPL10suppressor820.779123.356Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
125 RPL10Ainteractor880.75795.709Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
126 RPL11suppressor940.701129.758Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
127 RPL12interactor930.71694.745Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
128 RPL13Ainteractor760.82730.046Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
129 RPL14protein found in more fusions930.707150.166KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
130 RPL15interactor950.703103.863Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
131 RPL18interactor980.683140.057Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
132 RPL18Ainteractor820.750139.617Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
133 RPL19interactor900.72897.180DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
134 RPL21interactor900.739115.716Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
135 RPL22oncoprotein910.710124.154Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
136 RPL23interactor950.681256.074Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
137 RPL23Ainteractor900.75961.342Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
138 RPL24protein found in more fusions860.79742.033MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
139 RPL26oncoprotein550.78825.916TP2 (PF01254, IPR000678): Nuclear transition protein 2
Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
140 RPL26L1interactor450.79816.590Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
141 RPL27protein found in more fusions870.77457.529Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
142 RPL27Ainteractor820.79539.211Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
143 RPL28interactor450.78014.474Ribosomal_L28e (PF01778, IPR029004): Ribosomal L28e protein family
144 RPL3protein found in more fusions880.76976.233Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
145 RPL30interactor830.79247.893NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
146 RPL31interactor880.76156.099Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
147 RPL35interactor800.79750.087Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
XFP_N (PF09364, IPR018970): XFP N-terminal domain
148 RPL35Ainteractor620.89311.288Ribosomal_L35Ae (PF01247, IPR001780): Ribosomal protein L35Ae
149 RPL36interactor780.83128.769Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
150 RPL37Ainteractor740.85270.235Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
151 RPL38protein found in more fusions780.77459.209Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family
152 RPL4interactor1020.640206.900Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
153 RPL5suppressor960.706178.747Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
154 RPL6protein found in more fusions1050.636278.249Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
155 RPL7interactor950.690146.168Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
156 RPL7Aprotein found in more fusions880.73473.731Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
157 RPL8interactor900.72794.393Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
158 RPL9interactor850.78549.247Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6
159 RPLP0interactor1030.651149.877Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
160 RPLP1interactor730.802108.638Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
161 RPS10interactor880.75975.802S10_plectin (PF03501, IPR005326): Plectin/S10 domain
162 RPS11interactor830.79547.289Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
163 RPS13interactor900.74985.933Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
164 RPS14protein found in more fusions910.73773.753Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
165 RPS15interactor750.78159.035Ribosomal_S19 (PF00203, IPR002222): Ribosomal protein S19
Prok_Ub (PF14454, IPR032866): Prokaryotic Ubiquitin
166 RPS15Ainteractor900.732113.247Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
167 RPS16interactor960.71690.198Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
168 RPS17interactor620.82219.384Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
169 RPS18interactor870.78347.776Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
170 RPS19protein found in more fusions940.700165.953Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
171 RPS2interactor980.680142.478Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
172 RPS20interactor830.76375.617Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
173 RPS21interactor660.82460.677Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
174 RPS23protein found in more fusions830.79341.844Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
175 RPS24protein found in more fusions770.84624.017Fascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
176 RPS25interactor960.691148.835Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
177 RPS26interactor760.82744.427Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
178 RPS27protein found in more fusions720.86623.028Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
179 RPS27Linteractor440.9394.313E7 (PF00527, IPR000148): E7 protein, Early protein
Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
180 RPS28interactor620.82325.078Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
181 RPS3interactor1010.662161.031KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
182 RPS3Ainteractor1020.669135.468Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
183 RPS4Xinteractor1010.673172.419KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
184 RPS5protein found in more fusions830.77863.304Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
185 RPS6protein found in more fusions980.686164.451Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
186 RPS7interactor880.74589.315Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
187 RPS8interactor1020.665152.316Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
188 RPS9interactor910.73686.238Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
189 RPSAinteractor820.77376.438Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
190 SH3GL1oncoprotein160.48625.306BAR (PF03114, IPR004148, SM00721): BAR domain
PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
191 SH3GLB1suppressor140.50017.788BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
192 SIRT7interactor590.544157.442DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
193 SLC27A2interactor30.6670.400AMP-binding (PF00501, IPR000873): AMP-binding enzyme
AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
194 SLC2A1interactor50.7001.086Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
195 SLC6A4interactor21.00005HT_transport_N (PF03491, IPR013086): Serotonin (5-HT) neurotransmitter transporter, N-terminus
SNF (PF00209, IPR000175): Sodium:neurotransmitter symporter family
196 SMARCB1suppressor80.5712.517SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
197 SOX2oncoprotein90.2508.047HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
198 SRPK2oncoprotein180.45626.997DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
199 SSR3interactor60.5336.167TRAP-gamma (PF07074, IPR009779): Translocon-associated protein, gamma subunit (TRAP-gamma)
200 SUZ12suppressor150.49517.083DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
201 TAP1oncoprotein60.6673.667ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
202 TAPBPinteractor60.6003.686C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
203 TCTN1interactor90.6672.636DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
204 TCTN3interactor120.50019.755DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
205 THG1Linteractor110.6007.574Thg1 (PF04446, IPR024956): tRNAHis guanylyltransferase
Thg1C (PF14413, IPR025845): Thg1 C terminal domain
206 TKTprotein found in more fusions260.40765.926Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
207 TP53suppressor830.528367.261DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
208 TPD52L2protein found in more fusions170.35832.298TPD52 (PF04201, IPR007327): Tumour protein D52 family
209 TPT1interactor60.4670.897TCTP (PF00838, IPR018105): Translationally controlled tumour protein
210 TRIM21interactor80.6190.676DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
211 TSHRoncoprotein30.6670.1827tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
212 TUBG1protein found in more fusions550.593148.212Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
213 TUBGCP2interactor130.47412.817Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
214 TUBGCP4interactor180.7918.766Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
215 U2AF2protein found in more fusions440.411127.131RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
216 UBA52interactor270.75216.630Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
217 UBCprotein found in more fusions510.367249.363ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
218 UBE3Aoncoprotein150.36321.054HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
219 UBL4Ainteractor750.70195.509ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
220 UPF2interactor130.5158.343DDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
221 VCPprotein found in more fusions620.382331.237AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
222 VWFinteractor30.6670.667Antistasin (PF02822, IPR004094): Antistasin family
C8 (PF08742, IPR014853, SM00832): C8 domain
Metallothio_5 (PF02067, IPR000966): Metallothionein family 5
Pacifastin_I (PF05375, IPR008037): Pacifastin inhibitor (LCMII)
TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
VWD (PF00094, IPR001846, SM00216): von Willebrand factor type D domain
VWA_N2 (PF16164, IPR032361): VWA N-terminal
223 WDR1interactor110.7452.773eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
224 YWHAEoncoprotein350.46661.40314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
225 YWHAQinteractor340.405103.44514-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ATP1B2interactorAcyl_transf_1 (PF00698, IPR014043): Acyl transferase domain
2 CALRparental proteinCalreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
3 LOC101929876interactorNA
4 RNY1interactorNA
5 RNY3interactorNA
6 RNY4interactorNA
7 RPLP0P6interactorNA
8 RPLP2parental proteinRibosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
9 TFinteractorTransferrin (PF00405, IPR001156, SM00094): Transferrin

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