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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BU675238 is the fusion of parental proteins MAGED1 (from a repository: Sun Feb 5 11:46:24 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)90
The number (and %) of the onco-proteins19 (21.11 %)
The number (and %) of the tumor suppressors12 (13.33 %)
Total number of binary PPIs (saturation %)333 (8.31 %)
The number (and %) of affected PPIs89 (26.73 %)
The number of possible different fusions13
PPI diameter2
PPI radius1
The average degree of PPI6.622
Assortativity coefficient-0.1716
The network average Clustering coefficient0.525
The number (and %) of a zero Clustering coefficients8 (8.89 %)
The number (and %) of a zero Betweenness Centrality26 (28.89 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: MAGED1 All fusions
: BU675238;
Proteins found in more fusions RBFOX2 (see 2 fusions); ILK (see 1 fusions); BAG3 (see 4 fusions); NTRK1/TFG (see 1 fusions); TRIM28 (see 1 fusions); UBR5 (see 4 fusions); PJA2 (see 1 fusions); MAP3K7 (see 7 fusions); CUL3 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); COPG1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BU675238chimera890.0536252.269MAGE (PF01454, IPR002190): MAGE family
2 AATFoncoprotein40.6671.667DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TRAUB (PF08164, IPR012617): Apoptosis-antagonizing transcription factor, C-terminal
Vif (PF00559, IPR000475): Retroviral Vif (Viral infectivity) protein
AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
3 AKAP8Linteractor80.42911.500AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95)
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
4 AKAP9oncoprotein21.0000ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
Hema_stalk (PF08720, IPR014831): Influenza C hemagglutinin stalk
IncA (PF04156, IPR007285): IncA protein
Laminin_II (PF06009, IPR010307): Laminin Domain II
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
ApoO (PF09769, IPR019166): Apolipoprotein O
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
Macoilin (PF09726, IPR019130): Transmembrane protein
PACT_coil_coil (PF10495, IPR019528): Pericentrin-AKAP-450 domain of centrosomal targeting protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
FlxA (PF14282, IPR025577): FlxA-like protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
FAM76 (PF16046, IPR032017): FAM76 protein
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
5 ANKRD28interactor70.4298.033Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
6 ATXN10interactor21.0000RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
7 BAG3oncoprotein40.6671.000BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
8 BAG6interactor70.4676.333DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
9 BARD1suppressor80.33311.500BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
10 BHLHE40interactor90.32117.167Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
11 BIRC8interactor21.0000BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
12 BRCA2suppressor40.5002.333BRCA-2_helical (PF09169, IPR015252): BRCA2, helical
BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1
BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
BRCA2 (PF00634, IPR002093): BRCA2 repeat
Tower (PF09121, IPR015205): Tower
13 BTRConcoprotein100.30622.733WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
14 CA8interactor100Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
15 CALML5interactor21.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
16 CCAR2suppressor60.5333.450DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide
IncA (PF04156, IPR007285): IncA protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DBC1 (PF14443, IPR025954, SM01122): DBC1
S1-like (PF14444, IPR025223): S1-like
17 CCDC33interactor40.6672.000C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
18 CEP135interactor40.8330.400DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPD52 (PF04201, IPR007327): Tumour protein D52 family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
19 CEP192interactor70.33311.800Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
TMEM131_like (PF12371, IPR022113): Transmembrane protein 131-like
MYCBPAP (PF14646, IPR032707): MYCBP-associated protein family
ASH (PF15780, IPR031549): Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
20 CEP250interactor80.28613.900ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
21 CHUKsuppressor70.5334.667Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
22 COPG1protein found in more fusions100.5289.952Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
COP-gamma_platf (PF08752, IPR013040): Coatomer gamma subunit appendage platform subdomain
Coatomer_g_Cpla (PF16381, IPR032154): Coatomer subunit gamma-1 C-terminal appendage platform
23 COPG2interactor60.8000.800Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
COP-gamma_platf (PF08752, IPR013040): Coatomer gamma subunit appendage platform subdomain
Coatomer_g_Cpla (PF16381, IPR032154): Coatomer subunit gamma-1 C-terminal appendage platform
24 CUL3protein found in more fusions270.175214.133Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
25 DEUP1suppressor31.0000APG6 (PF04111, IPR007243): Autophagy protein Apg6
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
CEP63 (PF17045, IPR031470): Centrosomal protein of 63 kDa
26 DNAAF5interactor40.6671.200HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
27 EIF3Eoncoprotein30.6670.133eIF3_N (PF09440, IPR019010): eIF3 subunit 6 N terminal domain
PCI (PF01399, IPR000717, SM00088): PCI domain
HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain
SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
28 EIF4E2interactor21.0000IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
29 EP300oncoprotein100.27821.833Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
30 FAF2interactor90.46411.233DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
31 FANCIinteractor60.4673.869DUF3972 (PF13118, IPR025002): Protein of unknown function (DUF3972)
FANCI_S1-cap (PF14674, IPR029305): FANCI solenoid 1 cap
FANCI_S1 (PF14675, IPR029308): FANCI solenoid 1
FANCI_S2 (PF14676, IPR026171): FANCI solenoid 2
FANCI_S3 (PF14677, IPR029313): FANCI solenoid 3
FANCI_S4 (PF14678, IPR029314): FANCI solenoid 4
FANCI_HD1 (PF14679, IPR029310): FANCI helical domain 1
FANCI_HD2 (PF14680, IPR029312): FANCI helical domain 2
32 FBXO7interactor21.0000Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
F-box-like (PF12937, IPR001810): F-box-like
33 GCN1interactor70.4297.452Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
34 GPR135interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
Fumarate_red_D (PF02313, IPR003418): Fumarate reductase subunit D
35 HEATR1interactor40.5000.619BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain
HEAT (PF02985, IPR000357): HEAT repeat
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
CLASP_N (PF12348, IPR024395): CLASP N terminal
U3snoRNP10 (PF12397, IPR022125): U3 small nucleolar RNA-associated protein 10
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
36 HIVEP1suppressor31.0000PHD (PF00628, IPR019787, SM00249): PHD-finger
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_7 (PF15269): Zinc-finger
37 IARSinteractor31.0000Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
38 ILKsuppressor130.27330.967Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
39 IRAK1interactor100.30622.400Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
40 IRS4interactor80.5008.302CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
PH_11 (PF15413): Pleckstrin homology domain
41 KPNA2interactor50.5003.833Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
42 KRTAP19-5interactor21.0000KRTAP (PF11759, IPR021743): Keratin-associated matrix
43 LRPPRCinteractor60.4674.667DED (PF01335, IPR001875, SM00031): Death effector domain
MA3 (PF02847, IPR003891, SM00544): MA3 domain
PPR (PF01535, IPR002885): PPR repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
TPR_19 (PF14559): Tetratricopeptide repeat
PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
44 MAGED2interactor70.4766.667CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
MAGE (PF01454, IPR002190): MAGE family
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
45 MAP3K7oncoprotein70.4677.333Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
46 MDFIinteractor70.4009.000MDFI (PF15316, IPR026134): MyoD family inhibitor
47 MEOX2interactor21.0000Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
48 MTHFD1Linteractor50.7001.050FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase
THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
49 NANOGinteractor80.28612.967Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
50 NGFRsuppressor31.0000LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
51 NOC2Linteractor60.4006.286CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Noc2 (PF03715, IPR005343): Noc2p family
CEND1 (PF15677, IPR020162): Cell cycle exit and neuronal differentiation protein 1
52 NREPinteractor100DUF2719 (PF10891, IPR020122): Protein of unknown function (DUF2719)
Alveol-reg_P311 (PF11092, IPR024417): Neuronal protein 3.1 (p311)
53 NTRK1oncoprotein330.119354.067I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
54 NUMBLinteractor31.0000DUF1932 (PF09130, IPR015814): Domain of unknown function (DUF1932)
NumbF (PF06311, IPR010449): NUMB domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
55 NUP160interactor40.6670.383Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
56 PCM1oncoprotein80.35711.667FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
AAA_23 (PF13476): AAA domain
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829)
57 PCNAoncoprotein80.3819.300PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
58 PITX1oncoprotein21.0000Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
OAR (PF03826, IPR003654): OAR domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
59 PJA1interactor60.4003.500zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
60 PJA2protein found in more fusions70.6005.333zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
61 PLK1suppressor100.31126.467Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
62 PLK4interactor70.3337.400ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
63 PRKAB2interactor70.4008.400AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain
AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase
64 RBFOX1interactor80.38111.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
65 RBFOX2protein found in more fusions120.25536.567RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
66 RBM23interactor30.6670.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
RSRP (PF17069): Arginine/Serine-Rich protein 1
67 RFX1interactor100Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RFX1_trans_act (PF04589, IPR007668): RFX1 transcription activation region
RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain
68 RHOXF2interactor90.32118.500DUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
69 RNF8suppressor50.5001.833FHA (PF00498, IPR000253, SM00240): FHA domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
70 ROR2suppressor40.6670.667I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Kringle (PF00051, IPR000001): Kringle domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Fz (PF01392, IPR020067, SM00063): Fz domain
TMEM154 (PF15102, IPR028064): TMEM154 protein family
71 RPS6KB2interactor70.3339.733Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
72 SENP3interactor80.5368.900Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
73 SIRT7interactor180.15788.033DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
74 SMAP2interactor100ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
Spore-coat_CotD (PF11122, IPR020108): Inner spore coat protein D
75 SNRPCinteractor40.6671.067zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
76 SPTLC1interactor100Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
77 TAB1interactor31.0000PP2C (PF00481, IPR001932): Protein phosphatase 2C
78 TELO2interactor41.0000Telomere_reg-2 (PF10193, IPR019337): Telomere length regulation protein
HEAT_2 (PF13646): HEAT repeats
79 TFGoncoprotein41.0000ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
80 TIMM50interactor50.6003.067NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
81 TOLLIPinteractor70.4007.000C2 (PF00168, IPR000008, SM00239): C2 domain
CUE (PF02845, IPR003892, SM00546): CUE domain
82 TRIM28protein found in more fusions70.6003.167ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
83 TTC23interactor30.6671.000DUF3856 (PF12968, IPR024552): Domain of Unknown Function (DUF3856)
TPR_12 (PF13424): Tetratricopeptide repeat
84 TTC32interactor21.0000DUF1936 (PF09151, IPR015234): Domain of unknown function (DUF1936)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
85 UBR5protein found in more fusions90.42911.617CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SDA1 (PF05285, IPR007949): SDA1
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
86 UBXN1interactor90.5368.733Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UBX (PF00789, IPR001012, SM00166): UBX domain
87 UNC5Asuppressor100Death (PF00531, IPR000488, SM00005): Death domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
DUF3377 (PF11857, IPR021805): Domain of unknown function (DUF3377)
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
UPA (PF17217): UPA domain
88 USP9Xinteractor90.33315.483DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722)
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
89 XIAPinteractor60.5004.667BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
90 ZNF488interactor100zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 C1orf94interactorDUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
2 CCDC14interactorCCDC14 (PF15254, IPR029343): Coiled-coil domain-containing protein 14
3 CCDC59interactorrRNA_processing (PF08524, IPR013730): rRNA processing
4 DAB1interactorPID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
5 DAZAP2interactorDAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
6 EIF3JinteractoreIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit
7 HSPB1oncoproteinHSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
8 KIAA0753interactorMNR (PF15718, IPR031447): Protein moonraker
9 MAGED1parental proteinMAGE (PF01454, IPR002190): MAGE family
10 MAPK3oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
11 MPC1interactorMPC (PF03650, IPR005336): Uncharacterised protein family (UPF0041)
12 NEDD8interactorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
13 NUP205interactorNup192 (PF11894, IPR021827): Nuclear pore complex scaffold, nucleoporins 186/192/205
14 PCK1interactorPEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
15 RBPMSinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
16 RNF185interactorzf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
17 SLC25A1interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
18 SMC3oncoproteinSMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
19 STILoncoproteinSTIL_N (PF15253, IPR026123): SCL-interrupting locus protein N-terminus

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