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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BU662818 is the fusion of parental proteins ATF2, DDIT3 (from a repository: Thu Feb 2 06:29:31 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)177
The number (and %) of the onco-proteins69 (38.98 %)
The number (and %) of the tumor suppressors33 (18.64 %)
Total number of binary PPIs (saturation %)1018 (6.54 %)
The number (and %) of affected PPIs176 (17.29 %)
The number of possible different fusions41
PPI diameter2
PPI radius1
The average degree of PPI10.644
Assortativity coefficient-0.2413
The network average Clustering coefficient0.469
The number (and %) of a zero Clustering coefficients18 (10.17 %)
The number (and %) of a zero Betweenness Centrality35 (19.77 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: ATF2,DDIT3 All fusions
: BU662818;
Proteins found in more fusions APP (see 4 fusions); TPM1 (see 2 fusions); SMAD4 (see 2 fusions); YWHAG (see 1 fusions); HSP90AA1 (see 2 fusions); MAPK1 (see 1 fusions); ZDHHC17 (see 2 fusions); ACTN1 (see 3 fusions); CUL3 (see 1 fusions); AHNAK (see 2 fusions); HDAC4 (see 1 fusions); NCOA6 (see 1 fusions); CREB1 (see 2 fusions); MAPK9 (see 3 fusions); CDK6 (see 1 fusions); YY1 (see 2 fusions); BCAP31 (see 3 fusions); MAPK14 (see 1 fusions); CALR (see 6 fusions); CREBBP (see 6 fusions); ARF1 (see 2 fusions); MDH2 (see 1 fusions); TFRC (see 1 fusions); BATF3 (see 1 fusions); CTTN (see 1 fusions); KAT5 (see 3 fusions); FOS (see 4 fusions); CSNK2A1 (see 1 fusions); HDAC5 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); PML (see 4 fusions); CCND1 (see 1 fusions); SS18 (see 1 fusions); PRKCE (see 3 fusions); SMAD3 (see 3 fusions); GAPDH (see 2 fusions); ATP1A1/MAPK1 (see 1 fusions); ACADVL (see 1 fusions); RTN4 (see 11 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BU662818chimera1760.05023726.632bZIP_1 (PF00170, IPR004827): bZIP transcription factor
2 ACADVLprotein found in more fusions200Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
3 ACTN1protein found in more fusions80.33311.000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
4 AHCYinteractor80.3817.629AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
5 AHNAKsuppressor70.4677.500DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945)
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein
DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993)
DUF4097 (PF13349, IPR025164): Putative adhesin
Ntox37 (PF15535, IPR029108): Bacterial toxin 37
6 AHSGinteractor100Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
7 ALDOAinteractor150.51618.517Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
8 ANXA3interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
RPT (PF13446, IPR025305): A repeated domain in UCH-protein
9 APPprotein found in more fusions450.137639.767APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
10 ARF1suppressor70.6005.167Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
11 ARF4interactor80.5367.967Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
12 ATF1oncoprotein100.4679.978bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
13 ATF3suppressor250.40275.670bZIP_1 (PF00170, IPR004827): bZIP transcription factor
14 ATF4oncoprotein200.48539.146bZIP_1 (PF00170, IPR004827): bZIP transcription factor
15 ATMsuppressor100.50013.133FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
16 ATP1A1protein found in more fusions110.38225.794Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
Tetraspannin (PF00335, IPR018499): Tetraspanin family
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
17 ATP2A2interactor60.4004.858Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
18 ATP2A3interactor100Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
19 ATP5Binteractor140.34139.657AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
20 BACH1interactor80.42910.233BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
21 BATFoncoprotein100.8890.807bZIP_1 (PF00170, IPR004827): bZIP transcription factor
22 BATF2suppressor70.8100.807bZIP_1 (PF00170, IPR004827): bZIP transcription factor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
23 BATF3protein found in more fusions100.8890.807bZIP_1 (PF00170, IPR004827): bZIP transcription factor
24 BCAP31protein found in more fusions70.4674.238Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
25 BSGinteractor40.6671.667Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
26 CALRoncoprotein140.42320.621Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
27 CALUinteractor70.6193.575EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
28 CANXinteractor140.39633.143Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
29 CAP1interactor60.4002.922CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
30 CCDC6oncoprotein50.5002.936CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
FAM199X (PF15814, IPR029672): Protein family FAM199X
31 CCND1oncoprotein90.39311.383Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
32 CD44suppressor40.6671.667VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit
Xlink (PF00193, IPR000538, SM00445): Extracellular link domain
S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
33 CDK6suppressor70.5333.652Pkinase (PF00069, IPR000719): Protein kinase domain
34 CEBPAsuppressor210.42154.130Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
35 CEBPBoncoprotein140.57711.059RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
36 CEBPEinteractor150.62612.695Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
37 CEBPGinteractor140.6798.400bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
38 CFL1interactor190.28187.745Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
39 CLIC1interactor100GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
40 COLGALT1interactor21.0000Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein)
Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
41 CREB1oncoprotein220.31084.929bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
42 CREB3interactor61.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
43 CREB5interactor90.46410.483bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Zip (PF02535, IPR003689): ZIP Zinc transporter
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
44 CREBBPsuppressor280.348101.694Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
45 CSNK2A1oncoprotein200.29876.536Pkinase (PF00069, IPR000719): Protein kinase domain
46 CTNNB1oncoprotein190.26386.512Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
47 CTNND1suppressor50.8001.000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
48 CTTNoncoprotein70.4005.771FadA (PF09403, IPR018543): Adhesion protein FadA
HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
49 CUL3protein found in more fusions400.165458.671Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
50 DDX39Binteractor70.4768.900DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
51 DLDinteractor60.4676.833Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
52 DNMT3Linteractor140.49514.328CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
53 EEF2interactor120.30331.417EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
54 EIF5Ainteractor40.5002.400EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
55 ENO1oncoprotein150.43831.287Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
56 EP300oncoprotein390.215365.868Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
57 ERP29interactor21.0000ERp29 (PF07749, IPR011679): Endoplasmic reticulum protein ERp29, C-terminal domain
ERp29_N (PF07912, IPR012883): ERp29, N-terminal domain
58 ETS1oncoprotein110.5459.212Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
59 EXOSC8interactor200RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
60 FHsuppressor90.50010.072Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
61 FOSoncoprotein270.354101.743bZIP_1 (PF00170, IPR004827): bZIP transcription factor
62 FOSL1oncoprotein120.6217.870bZIP_1 (PF00170, IPR004827): bZIP transcription factor
63 FOSL2oncoprotein100.44414.302bZIP_1 (PF00170, IPR004827): bZIP transcription factor
64 FUBP1oncoprotein90.33317.186DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
65 GANABsuppressor90.6676.297Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
DUF5110 (PF17137): Domain of unknown function (DUF5110)
66 GAPDHoncoprotein170.43333.086Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
67 GLSinteractor21.0000Glutaminase (PF04960, IPR015868): Glutaminase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
68 GLUD2interactor100ELFV_dehydrog (PF00208, IPR006096, SM00839): Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
SF3b10 (PF07189, IPR009846): Splicing factor 3B subunit 10 (SF3b10)
69 GNB2interactor40.5002.286WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CALM_bind (PF16025): Calcium-dependent calmodulin binding
WD40_like (PF17005, IPR031544): WD40-like domain
70 GP1BAinteractor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
71 GRPEL1interactor70.4676.667GrpE (PF01025, IPR000740): GrpE
72 GSTP1suppressor60.4003.571GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
73 H2AFXsuppressor230.225148.933Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
74 H2AFYinteractor31.0000DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Macro (PF01661, IPR002589, SM00506): Macro domain
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
75 HADHAinteractor40.5002.1673HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
76 HADHBinteractor40.6671.333Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
77 HDAC4oncoprotein150.41825.658Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
78 HDAC5protein found in more fusions380.158426.580Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
79 HK1interactor40.5001.286Hexokinase_1 (PF00349, IPR022672): Hexokinase
Hexokinase_2 (PF03727, IPR022673): Hexokinase
80 HMGA1oncoprotein120.56113.225AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
81 HNRNPH1oncoprotein60.5336.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
82 HSP90AA1oncoprotein300.232214.765HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
83 HSP90B1suppressor160.39247.085CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
84 HSPH1oncoprotein70.5244.336HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
85 IRF2BP1interactor21.0000zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
IRF-2BP1_2 (PF11261, IPR022750): Interferon regulatory factor 2-binding protein zinc finger
86 ITGA2interactor31.0000FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
FG-GAP_2 (PF14312, IPR013517): FG-GAP repeat
87 ITGB1suppressor80.35715.400EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
88 ITGB4oncoprotein21.0000Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain
EGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
SEA (PF01390, IPR000082, SM00200): SEA domain
STOP (PF05217, IPR024963): STOP protein
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
89 JUNoncoprotein410.276318.828bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
90 JUNBoncoprotein180.41239.820bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
91 JUNDoncoprotein160.41740.324bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
92 KAT5suppressor240.289111.107MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
93 KIFC3oncoprotein50.5002.000Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
94 KRT18interactor60.5002.967Filament (PF00038, IPR001664): Intermediate filament protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
95 KRT7interactor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
96 KRT8interactor60.5334.186Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
97 LDHAinteractor190.35361.731Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
98 LDHBinteractor170.36744.997Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
99 LLGL2interactor200Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal
LLGL (PF08366, IPR013577): LLGL2
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
100 MAPK1oncoprotein210.32182.903Pkinase (PF00069, IPR000719): Protein kinase domain
101 MAPK10suppressor70.5333.198Pkinase (PF00069, IPR000719): Protein kinase domain
102 MAPK11interactor60.4673.686HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Pkinase (PF00069, IPR000719): Protein kinase domain
103 MAPK13oncoprotein30.6670.286Pkinase (PF00069, IPR000719): Protein kinase domain
104 MAPK14oncoprotein140.37229.583Pkinase (PF00069, IPR000719): Protein kinase domain
105 MAPK3oncoprotein100.50010.821Pkinase (PF00069, IPR000719): Protein kinase domain
106 MAPK8oncoprotein160.35243.072DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
107 MAPK9suppressor90.5714.385Pkinase (PF00069, IPR000719): Protein kinase domain
Kinase-like (PF14531, IPR027916): Kinase-like
108 MDH2protein found in more fusions90.35712.419Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
109 MLH1suppressor110.30926.233DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
110 MRE11Aoncoprotein90.6794.019APG6 (PF04111, IPR007243): Autophagy protein Apg6
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain
111 NACAoncoprotein50.5002.015NAC (PF01849, IPR002715): NAC domain
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
CitT (PF12431, IPR028141): Transcriptional regulator
112 NBNsuppressor80.6794.019FHA (PF00498, IPR000253, SM00240): FHA domain
Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1
NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
113 NCOA6oncoprotein100.6945.748DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Presenilin (PF01080, IPR001108): Presenilin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
114 NFATC1oncoprotein130.52613.105RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
115 NFYAinteractor70.7621.158CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus
FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase
DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237)
116 OATinteractor21.0000Aminotran_3 (PF00202, IPR005814): Aminotransferase class-III
117 P4HBinteractor180.37552.400Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
118 PCBP1oncoprotein90.5288.833Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
119 PCNAoncoprotein210.30094.013PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
120 PDIA3interactor110.32727.216Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
121 PDIA4interactor40.8330.500Calsequestrin (PF01216, IPR001393): Calsequestrin
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
FAM176 (PF14851): FAM176 family
122 PHBsuppressor160.30058.930Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
123 PHB2interactor110.38222.338DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
124 PKMoncoprotein200.34272.869PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
125 PMLsuppressor190.34057.864zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
126 PPIFinteractor21.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
127 PRDX5interactor70.5712.991Redoxin (PF08534, IPR013740): Redoxin
NAD_binding_10 (PF13460, IPR016040): NAD(P)H-binding
128 PRKCEsuppressor70.5334.733C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
129 RAB11Aoncoprotein70.6195.400Ras (PF00071, IPR001806, SM00173): Ras family
130 RAB14oncoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
131 RAB2Aoncoprotein100.46716.667Ras (PF00071, IPR001806, SM00173): Ras family
132 RAB2Boncoprotein21.0000PNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase
Ras (PF00071, IPR001806, SM00173): Ras family
133 RAB7Asuppressor100.33322.800Ras (PF00071, IPR001806, SM00173): Ras family
134 RB1suppressor170.37546.206RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
135 RHOConcoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
136 RPN1oncoprotein100.5789.327Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
137 RPS6KA5interactor100.48910.075Choline_kinase (PF01633): Choline/ethanolamine kinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
138 RTN4suppressor60.7002.500CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Reticulon (PF02453, IPR003388): Reticulon
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
139 RUVBL2oncoprotein130.40922.079TIP49 (PF06068, IPR010339): TIP49 C-terminus
140 S100A10oncoprotein40.6671.000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
141 S100A11suppressor200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
142 S100A2suppressor200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
143 SCGNinteractor100EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_10 (PF14788): EF hand
144 SERPINH1interactor60.4006.733Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
145 SFNsuppressor70.6671.86714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
146 SFXN1interactor21.0000Mtc (PF03820, IPR004686): Tricarboxylate carrier
147 SLC25A12interactor40.6671.667Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
148 SLC25A13interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
149 SLC3A2interactor70.4769.000Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain
DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459)
SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus
150 SMAD3oncoprotein280.325145.851MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
151 SMAD4suppressor150.47326.816MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
152 SQRDLinteractor21.0000Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
153 SRA1interactor90.4447.501SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1)
154 SS18oncoprotein60.5002.767SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
155 STIP1interactor100.42219.186TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
156 TACSTD2oncoprotein100Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749)
157 TAGLN2interactor110.36418.671Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
158 TFRConcoprotein40.6670.286PA (PF02225, IPR003137): PA domain
Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
TFR_dimer (PF04253, IPR007365): Transferrin receptor-like dimerisation domain
DUF3855 (PF12967, IPR024482): Domain of Unknown Function with PDB structure (DUF3855)
159 THRBsuppressor50.5001.286zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
160 TIMM9interactor100zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
161 TLE1interactor50.5001.833TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
162 TMED10interactor100EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
163 TMX1interactor21.0000OST3_OST6 (PF04756, IPR021149): OST3 / OST6 family, transporter family
Thioredoxin (PF00085, IPR013766): Thioredoxin
FAM176 (PF14851): FAM176 family
164 TPM1protein found in more fusions60.5004.667Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
165 TPM4oncoprotein60.4007.667Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
166 TRIB3interactor50.7000.718Pkinase (PF00069, IPR000719): Protein kinase domain
167 TUBBinteractor110.56410.762Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
168 UBE2Iinteractor210.39555.913UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
169 UQCRC1interactor80.4649.867Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
170 UQCRC2oncoprotein170.35364.111Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
171 VAPAinteractor110.29130.033DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
172 VIMsuppressor90.42911.367Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
173 YWHABinteractor130.39728.16714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
174 YWHAGprotein found in more fusions170.30061.32914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
175 YY1protein found in more fusions150.45117.992zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
176 ZDHHC17protein found in more fusions200zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
177 ZSCAN31interactor100SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AMOTL2interactorHOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
2 ANXA1suppressorAnnexin (PF00191, IPR018502, SM00335): Annexin
3 ANXA5oncoproteinAnnexin (PF00191, IPR018502, SM00335): Annexin
4 APMAPinteractorStr_synth (PF03088, IPR018119): Strictosidine synthase
5 ATF2parental proteinbZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
6 ATP5OinteractorOSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit
7 ATPAF2interactorATP12 (PF07542, IPR011419): ATP12 chaperone protein
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
8 BACH2oncoproteinBTB (PF00651, IPR013069, SM00225): BTB/POZ domain
bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
9 BASP1suppressorBASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein)
10 C14orf80interactorDUF4509 (PF14970, IPR027996): Domain of unknown function (DUF4509)
DUF4510 (PF14971, IPR028100): Domain of unknown function (DUF4510)
11 CCDC153interactorDUF722 (PF05263, IPR007927): Protein of unknown function (DUF722)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
12 CCT2interactorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
13 CCT3interactorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
14 CCT4interactorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
15 CCT5interactorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
16 COPS3interactorRasGEF (PF00617, IPR001895, SM00147): RasGEF domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
17 COPS7AinteractorPCI (PF01399, IPR000717, SM00088): PCI domain
18 COPS8interactorCSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
19 CREB3L1suppressorbZIP_1 (PF00170, IPR004827): bZIP transcription factor
ELP6 (PF09807, IPR018627): Elongation complex protein 6
20 CSinteractorCitrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain
21 CUL1suppressorCullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
22 CYC1interactorCytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family
23 DBPinteractorbZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
24 DDIT3parental proteinIFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
25 DDOSTinteractorDDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta
26 DGCR2interactorUL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
27 EMSYoncoproteinENT (PF03735, IPR005491): ENT domain
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
GTA_TIM (PF13547, IPR025195): GTA TIM-barrel-like domain
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
28 EPAS1suppressorCorona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
29 ERO1AinteractorERO1 (PF04137, IPR007266): Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
30 F2interactorGla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Kringle (PF00051, IPR000001): Kringle domain
Thrombin_light (PF09396, IPR018992): Thrombin light chain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
Antifungal_pept (PF11410, IPR024206): Antifungal peptide
31 FSCN1oncoproteinFascin (PF06268, IPR022768): Fascin domain
32 GIPC1interactorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
33 HDAC1suppressorFSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
34 HDAC6oncoproteinHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
35 HOXA5interactorChorion_2 (PF03964, IPR005649): Chorion family 2
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
Terminase_5 (PF06056, IPR010332): Putative ATPase subunit of terminase (gpP-like)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
36 HSD17B14interactoradh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
37 HSPB1oncoproteinHSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
38 HSPD1suppressorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
39 HSPE1interactorCpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
40 IKBKGinteractorCENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
41 IMMTinteractorMitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
42 JDP2suppressorbZIP_1 (PF00170, IPR004827): bZIP transcription factor
43 KEAP1oncoproteinBACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
44 KPNA2interactorArm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
45 LDOC1LinteractorZapB (PF06005, IPR009252): Cell division protein ZapB
DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
46 LMO2oncoproteinCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
LIM (PF00412, IPR001781, SM00132): LIM domain
47 MAFFinteractorbZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
48 MAFGoncoproteinbZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
ThrE_2 (PF12821, IPR024528): Threonine/Serine exporter, ThrE
49 MARCKSsuppressorMARCKS (PF02063, IPR002101): MARCKS family
50 MCMBPinteractorMCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
51 MYDGFinteractorUPF0556 (PF10572, IPR018887): Uncharacterised protein family UPF0556
52 NFIL3interactorVert_IL3-reg_TF (PF06529, IPR010533): Vertebrate interleukin-3 regulated transcription factor
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
53 NME2P1interactorNA
54 PFN1suppressorProfilin (PF00235, IPR005455, SM00392): Profilin
55 POLR1DinteractorRNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
56 PPIBinteractorPro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
57 PTPN1suppressorY_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
58 RAI1interactorLin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
59 RPS3AinteractorRibosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
60 SHMT2interactorSHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
61 SLC2A1interactorSugar_tr (PF00083, IPR005828): Sugar (and other) transporter
62 SNAPC5interactorSNAPc19 (PF15497, IPR029138): snRNA-activating protein complex subunit 19, SNAPc subunit 19
63 SPOPsuppressorBACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
MATH (PF00917, IPR002083, SM00061): MATH domain
64 SSX2oncoproteinKRAB (PF01352, IPR001909, SM00349): KRAB box
65 SSX3interactorKRAB (PF01352, IPR001909, SM00349): KRAB box
66 SUMO1interactorRad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
67 TCP1interactorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
68 TNFSF12suppressorTNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
69 TPI1interactorTIM (PF00121, IPR000652): Triosephosphate isomerase
70 UTF1interactorMyb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
71 VDAC1interactorPorin_3 (PF01459, IPR027246): Eukaryotic porin
72 VDAC2interactorPorin_3 (PF01459, IPR027246): Eukaryotic porin
73 VDAC3interactorPorin_3 (PF01459, IPR027246): Eukaryotic porin
74 VPS37CinteractorMod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
75 ZBTB25interactorBTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
76 ZC3H14interactorPWI (PF01480, IPR002483, SM00311): PWI domain
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger

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