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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BU608204 is the fusion of parental proteins TPMT, PHACTR2 (from a repository: Thu Oct 17 18:22:22 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)2
The number (and %) of the onco-proteins2 (100.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)2 (200.00 %)
The number (and %) of affected PPIs1 (50.00 %)
The number of possible different fusions2
PPI diameter1
PPI radius1
The average degree of PPI1.000
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients2 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (100.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: PHACTR2,YES1 All fusions
: BU608204;
Proteins found in more fusions APP (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BU608204chimera100TPMT (PF05724, IPR008854): Thiopurine S-methyltransferase (TPMT)
2 APPprotein found in more fusions200APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
2 PHACTR2parental proteinRPEL (PF02755, IPR004018, SM00707): RPEL repeat
PRIMA1 (PF16101): Proline-rich membrane anchor 1
3 TPMTparental proteinTPMT (PF05724, IPR008854): Thiopurine S-methyltransferase (TPMT)

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