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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: BU608049 is the fusion of parental proteins VCL (from a repository: Sun Dec 25 21:30:11 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)100
The number (and %) of the onco-proteins31 (31.00 %)
The number (and %) of the tumor suppressors7 (7.00 %)
Total number of binary PPIs (saturation %)583 (11.78 %)
The number (and %) of affected PPIs99 (16.98 %)
The number of possible different fusions15
PPI diameter2
PPI radius1
The average degree of PPI11.060
Assortativity coefficient-0.2556
The network average Clustering coefficient0.495
The number (and %) of a zero Clustering coefficients11 (11.00 %)
The number (and %) of a zero Betweenness Centrality20 (20.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: VCL All fusions
: BU608049;
Proteins found in more fusions YWHAG (see 1 fusions); VCP (see 4 fusions); PAK4 (see 1 fusions); UBA3 (see 1 fusions); YWHAH (see 2 fusions); CDH1 (see 3 fusions); EWSR1 (see 2 fusions); GSS (see 1 fusions); YWHAZ (see 1 fusions); SORBS2 (see 4 fusions); G6PD (see 3 fusions); FN1/YWHAG (see 1 fusions); ECHS1 (see 1 fusions); PRPF40A (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BU608049chimera990.0946017.606Vinculin (PF01044, IPR006077): Vinculin family
2 ABI2suppressor50.5001.500Abi_HHR (PF07815, IPR012849): Abl-interactor HHR
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
3 AP3M1interactor40.8330.500Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
4 ASB7interactor100Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
5 ASCC2interactor30.6670.400CUE (PF02845, IPR003892, SM00546): CUE domain
BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3
6 ASNSoncoprotein160.46727.102Asn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
7 ATP6V1Ainteractor60.5334.317ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
8 BCAR1oncoprotein70.4765.710Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
9 C19orf57interactor31.0000DUF4671 (PF15710, IPR031441): Domain of unknown function (DUF4671)
10 CAPZBinteractor80.4644.437Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
11 CDCA5interactor31.0000Sororin (PF09666, IPR018605): Sororin protein
12 CDH1suppressor50.5001.000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
13 CDK2suppressor270.305111.290Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
14 CLTConcoprotein160.34241.475Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
15 CORO2Boncoprotein100DivIC (PF04977, IPR007060): Septum formation initiator
DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_4 (PF16300): Type of WD40 repeat
16 CTNNB1oncoprotein100.44412.421Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
17 CTPS1interactor80.5244.633CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
18 DAG1interactor41.0000DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
19 DCPSinteractor160.41736.730DcpS (PF05652, IPR008594): Scavenger mRNA decapping enzyme (DcpS) N-terminal
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
20 DNAJC5interactor100DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Baculo_F (PF12259, IPR022048): Baculovirus F protein
21 ECHS1protein found in more fusions110.6675.088ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
22 EIF5interactor170.61017.838CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
23 ERP44interactor100.6894.773Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
24 EWSR1oncoprotein200.28785.965RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
25 FBF1interactor40.5001.533DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
YlqD (PF11068, IPR021297): YlqD protein
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
26 FERMT2interactor170.50031.816FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
27 FN1oncoprotein260.33292.053fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
28 G6PDprotein found in more fusions160.66710.615G6PD_C (PF02781, IPR022675): Glucose-6-phosphate dehydrogenase, C-terminal domain
G6PD_N (PF00479, IPR022674): Glucose-6-phosphate dehydrogenase, NAD binding domain
29 GINS3interactor100.6446.702Sld5 (PF05916, IPR021151): GINS complex protein
30 GKAP1interactor200CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
31 GNAI3interactor80.8210.961G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
32 GSSprotein found in more fusions140.52616.491GSH_synth_ATP (PF03917, IPR005615): Eukaryotic glutathione synthase, ATP binding domain
33 HSPA5oncoprotein140.43623.773HSP70 (PF00012, IPR013126): Hsp70 protein
34 HSPA9oncoprotein180.34655.090HSP70 (PF00012, IPR013126): Hsp70 protein
35 ISOC1interactor150.63813.064Isochorismatase (PF00857, IPR000868): Isochorismatase family
Glyco_trans_4_4 (PF13579, IPR028098): Glycosyl transferase 4-like domain
36 ITGA4interactor210.38445.580FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
37 ITGB1suppressor110.49112.777EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
38 LIMA1suppressor130.52616.698LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
39 LPXNinteractor100LIM (PF00412, IPR001781, SM00132): LIM domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
40 MKNK2interactor21.0000ABC_trans_aux (PF03886, IPR005586): ABC-type transport auxiliary lipoprotein component
Pkinase (PF00069, IPR000719): Protein kinase domain
41 MPDZinteractor100L27_2 (PF09045, IPR015132): L27_2
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
MPDZ_u10 (PF16667, IPR032078): Unstructured region 10 on multiple PDZ protein
42 MSNoncoprotein220.31479.010DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
43 MYO1Cinteractor90.5568.668IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
44 NRAPinteractor100LIM (PF00412, IPR001781, SM00132): LIM domain
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
45 NTRK1oncoprotein550.169840.528I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
46 PAK4protein found in more fusions100.7503.133PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
47 PDCD10interactor130.28230.330DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
CENP-L (PF13092, IPR025204): Kinetochore complex Sim4 subunit Fta1
48 PDHA1interactor60.6001.308E1_dh (PF00676, IPR001017): Dehydrogenase E1 component
49 PDIA4interactor140.58213.724Calsequestrin (PF01216, IPR001393): Calsequestrin
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
FAM176 (PF14851): FAM176 family
50 PFASinteractor160.45032.524AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
51 PGM5interactor100PGM_PMM_I (PF02878, IPR005844): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879, IPR005845): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880, IPR005846): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408, IPR005843): Phosphoglucomutase/phosphomannomutase, C-terminal domain
52 PICALMoncoprotein140.49517.574ANTH (PF07651, IPR011417): ANTH domain
53 PPHLN1interactor100Lge1 (PF11488): Transcriptional regulatory protein LGE1
HERV-K_REC (PF15695): Rec (regulator of expression encoded by corf) of HERV-K-113
54 PPP5Cinteractor80.6793.665Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PPP5 (PF08321, IPR013235): PPP5 TPR repeat region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
55 PRPF40Aprotein found in more fusions70.5332.271FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
56 PSME1interactor200PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)
57 PXNoncoprotein140.33042.501LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
58 RAP1GDS1oncoprotein150.57116.256Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
59 RBM26interactor50.7003.000Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TT_ORF1 (PF02956, IPR004219): TT viral orf 1
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Nup35_RRM_2 (PF14605): Nup53/35/40-type RNA recognition motif
60 RPS27Ainteractor60.6670.846DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
61 SCAF4interactor30.6671.000CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
62 SDHAF2oncoprotein21.0000Sdh5 (PF03937, IPR005631): Flavinator of succinate dehydrogenase
Peroxidase_2 (PF01328, IPR000028): Peroxidase, family 2
Reovirus_cap (PF00979, IPR000153): Reovirus outer capsid protein, Sigma 3
63 SEC16Ainteractor100.6006.682APC_r (PF05923): APC repeat
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
64 SELEoncoprotein21.0000EGF (PF00008, IPR000742, SM00181): EGF-like domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
65 SFNsuppressor130.48517.45714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
66 SIRT7interactor170.29441.578DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
67 SORBS1interactor30.6670.500SH3_2 (PF07653, IPR011511): Variant SH3 domain
Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
SCAB-ABD (PF16711, IPR032012): Actin-binding domain of plant-specific actin-binding protein
68 SORBS2oncoprotein80.5243.830Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
69 SPTAN1oncoprotein110.6009.555EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
70 SSU72interactor30.6670.667Ssu72 (PF04722, IPR006811): Ssu72-like protein
71 STK24interactor100.5286.440DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
72 SVILinteractor80.53610.952Gelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
73 TBCBinteractor130.65410.469CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain
74 TEKT1interactor100CI-B14_5a (PF07347, IPR009947): NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
Tektin (PF03148, IPR000435): Tektin family
75 TGFB1I1interactor31.0000LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
76 TLN1interactor130.39723.173DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Talin_middle (PF09141, IPR015224): Talin, middle domain
VBS (PF08913, IPR015009): Vinculin Binding Site
CoatB (PF10389, IPR008020): Bacteriophage coat protein B
LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein
I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM
77 TPI1interactor70.6004.222TIM (PF00121, IPR000652): Triosephosphate isomerase
78 TRIM15suppressor60.4002.867Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
79 TRIP6interactor80.39312.383DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
LIM (PF00412, IPR001781, SM00132): LIM domain
80 TUBA1Aoncoprotein90.5289.121Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
81 TUBB3interactor70.4763.771Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
82 TXNL1interactor60.5333.982PITH (PF06201, IPR010400): PITH domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
83 UBA3protein found in more fusions50.6671.667E2_bind (PF08825, IPR014929): E2 binding domain
ThiF (PF00899, IPR000594): ThiF family
84 UBFD1interactor120.5619.949ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
85 UBR1interactor50.7001.222ATPase_2 (PF01637, IPR011579): ATPase domain predominantly from Archaea
ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
86 UFC1interactor30.6670.667UFC1 (PF08694, IPR014806): Ubiquitin-fold modifier-conjugating enzyme 1
87 UNKinteractor140.29735.001MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
88 URM1interactor50.5003.000Urm1 (PF09138, IPR015221): Urm1 (Ubiquitin related modifier)
89 USO1interactor51.0000Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Uso1_p115_head (PF04869, IPR006953): Uso1 / p115 like vesicle tethering protein, head region
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
MG1 (PF11974, IPR021868): Alpha-2-macroglobulin MG1 domain
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
90 VAPBinteractor40.6672.000ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
ZapB (PF06005, IPR009252): Cell division protein ZapB
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
91 VASPinteractor110.44415.079ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
92 VCAM1interactor180.33335.197C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
93 VCPprotein found in more fusions220.36767.432AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
94 XPO1interactor340.223295.530CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
95 YWHAEoncoprotein280.373111.40514-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
96 YWHAGprotein found in more fusions200.50333.95314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
97 YWHAHprotein found in more fusions200.59622.53314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
98 YWHAQinteractor240.37085.21914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
99 YWHAZprotein found in more fusions280.376100.21714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
100 ZC3HAV1Linteractor21.0000FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACTG1interactorActin (PF00022, IPR004000, SM00268): Actin
2 CTNNA1oncoproteinVinculin (PF01044, IPR006077): Vinculin family
3 GSNsuppressorGelsolin (PF00626, IPR007123): Gelsolin repeat
4 PPP1R2interactorIPP-2 (PF04979, IPR007062): Protein phosphatase inhibitor 2 (IPP-2)
5 SNRPFinteractorLSM (PF01423, IPR001163): LSM domain
6 VCLparental proteinVinculin (PF01044, IPR006077): Vinculin family

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