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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BQ771511 is the fusion of parental proteins PGGHG, NPR2 (from a repository: Mon Oct 14 16:23:06 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins1 (20.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)4 (40.00 %)
The number (and %) of affected PPIs4 (100.00 %)
The number of possible different fusions1
PPI diameter2
PPI radius1
The average degree of PPI1.600
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients5 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: SPAG8,PGGHG All fusions
: BQ771511;
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BQ771511chimera4012.000ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
HNOBA (PF07701, IPR011645): Heme NO binding associated
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
2 MOV10interactor100AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
3 NPPAinteractor100ANP (PF00212, IPR000663, SM00183): Atrial natriuretic peptide
4 NPPBinteractor100ANP (PF00212, IPR000663, SM00183): Atrial natriuretic peptide
5 NPPCinteractor100ANP (PF00212, IPR000663, SM00183): Atrial natriuretic peptide

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 NPR2parental proteinANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
HNOBA (PF07701, IPR011645): Heme NO binding associated
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
2 PAXIP1interactorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
3 PGGHGparental proteinGlyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
DUF2152 (PF10222, IPR018795): Uncharacterized conserved protein (DUF2152)

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