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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BQ315283 is the fusion of parental proteins PSMC2, PTPRF (from a repository: Wed Dec 7 14:45:13 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)182
The number (and %) of the onco-proteins61 (33.52 %)
The number (and %) of the tumor suppressors8 (4.40 %)
Total number of binary PPIs (saturation %)2460 (14.94 %)
The number (and %) of affected PPIs181 (7.36 %)
The number of possible different fusions35
PPI diameter2
PPI radius1
The average degree of PPI26.253
Assortativity coefficient-0.1312
The network average Clustering coefficient0.563
The number (and %) of a zero Clustering coefficients4 (2.20 %)
The number (and %) of a zero Betweenness Centrality15 (8.24 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: SLC26A5,PTPRF All fusions
: BQ315283;
Proteins found in more fusions GRK5 (see 4 fusions); PSMB3 (see 1 fusions); GRB2 (see 1 fusions); SHFM1/BAG3 (see 1 fusions); UBQLN1 (see 2 fusions); PSMB7 (see 2 fusions); NDC80 (see 1 fusions); PSMA7 (see 2 fusions); MAP3K5 (see 1 fusions); SNW1 (see 1 fusions); TRAF6 (see 1 fusions); HUWE1 (see 2 fusions); VPS26A (see 1 fusions); PPFIA1 (see 2 fusions); SNRNP200 (see 3 fusions); BAG3 (see 4 fusions); FKBP8 (see 1 fusions); PSMC5 (see 2 fusions); MAPK1 (see 1 fusions); UBE2C (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); PSME3 (see 2 fusions); UBC (see 1 fusions); PRPF40A (see 2 fusions); CRY2 (see 3 fusions); SQSTM1 (see 5 fusions); MAPT (see 1 fusions); EGFR (see 2 fusions); UBR5 (see 4 fusions); UBQLN2 (see 2 fusions); NID1 (see 1 fusions); PFKM (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BQ315283chimera1810.13614899.554AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Arylsulfotrans (PF05935, IPR010262): Arylsulfotransferase (ASST)
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
DUF3377 (PF11857, IPR021805): Domain of unknown function (DUF3377)
2 ABCE1interactor200.44431.701ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 ACADMoncoprotein120.50018.305Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
4 ADRM1interactor490.75137.670Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor
GET2 (PF08690, IPR028143): GET complex subunit GET2
RPN13_C (PF16550, IPR032368): UCH-binding domain
5 AMBRA1interactor330.67232.600Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
6 AMFRoncoprotein250.68131.790CUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
7 ARPC3interactor30.6670.250P21-Arc (PF04062, IPR007204): ARP2/3 complex ARPC3 (21 kDa) subunit
8 ATG4Cinteractor60.7331.008Peptidase_C54 (PF03416, IPR005078): Peptidase family C54
9 ATXN7interactor90.6675.169DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
10 BAG3oncoprotein300.57953.777BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
11 CADoncoprotein290.40665.461Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MGS (PF02142, IPR011607, SM00851): MGS-like domain
OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
12 CANXinteractor190.39835.211Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
13 CAV1suppressor120.33323.636Caveolin (PF01146, IPR001612): Caveolin
14 CCDC74Binteractor201.0000CCDC92 (PF14916): Coiled-coil domain of unknown function
CCDC74_C (PF14917, IPR029422): Coiled coil protein 74, C terminal
15 CCT2interactor350.41287.228Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
16 CCT3interactor340.45171.923Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
17 CCT4interactor310.40270.085Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
18 CCT6Ainteractor260.52633.503Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
19 CCT6Binteractor110.6555.505Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
20 CCT8interactor280.47643.864Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
21 CDC5Linteractor420.351205.304OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
22 CDKN2AIPinteractor80.4294.596XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD
23 CEACAM21interactor21.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
24 CIITAoncoprotein80.3577.342NACHT (PF05729): NACHT domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
25 CLIP1oncoprotein21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
CP12 (PF02672, IPR003823, SM01093): CP12 domain
DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
SlyX (PF04102, IPR007236): SlyX
ApoO (PF09769, IPR019166): Apolipoprotein O
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Leu_zip (PF15294): Leucine zipper
CLIP1_ZNF (PF16641, IPR032108): CLIP1 zinc knuckle
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
26 CRY2protein found in more fusions200.42127.957DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
27 CTNNB1oncoprotein150.35235.364Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
28 CUL3protein found in more fusions520.239410.348Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
29 CUL7protein found in more fusions320.267133.552ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
30 DCTN2interactor210.53722.559Dynamitin (PF04912): Dynamitin
31 DNAAF5interactor100.37815.611HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
32 DNAJA1interactor280.46852.374DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
33 DNAJA4interactor140.5718.760DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
34 EGFRoncoprotein350.257193.716Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
35 FBXO6interactor300.36369.871FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
36 FKBP8protein found in more fusions340.85016.303FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
37 FTSJ3interactor80.5363.381DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase
M16C_assoc (PF08367, IPR013578): Peptidase M16C associated
Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein
Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14
38 GFPT1interactor170.38232.593SIS (PF01380, IPR001347): SIS domain
GATase_6 (PF13522): Glutamine amidotransferase domain
39 GIT1interactor80.5248.067ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT
GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
FlxA (PF14282, IPR025577): FlxA-like protein
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
40 GRB2oncoprotein220.34848.730SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
41 GRK2interactor50.4003.667ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
42 GRK5protein found in more fusions110.4229.882Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
43 GTF2Binteractor70.4295.187Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
44 GTF2F1interactor90.41710.632TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
45 GTF2H1oncoprotein50.7001.733BSD (PF03909, IPR005607, SM00751): BSD domain
PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain
46 HACL1interactor200TPP_enzyme_C (PF02775, IPR011766): Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
TPP_enzyme_N (PF02776, IPR012001): Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
47 HEPACAM2interactor100V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
PgaD (PF13994, IPR023829): PgaD-like protein
48 HERC3interactor120.5308.522RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
49 HSPA4interactor280.265121.721Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
50 HUWE1oncoprotein610.429334.277BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
51 IPO4interactor100.37811.237HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
UME (PF08064, IPR012993, SM00802): UME (NUC010) domain
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
52 JUPsuppressor80.5005.640Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
53 KIAA0368interactor280.53761.250HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
Ecm29 (PF13001, IPR024372): Proteasome stabiliser
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
54 KPNA6interactor50.7000.493Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
55 LDHAinteractor190.33341.382Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
56 LDHBinteractor170.45032.080Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
57 MAP3K5oncoprotein80.7140.949Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
58 MAPK1oncoprotein160.27641.585Pkinase (PF00069, IPR000719): Protein kinase domain
59 MAPTprotein found in more fusions80.8100.768Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
60 MCFD2interactor120.62113.149EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
61 MID1oncoprotein170.7925.652Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
62 MID2interactor110.6006.778fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
63 MRPS16interactor51.0000Ribosomal_S16 (PF00886, IPR000307): Ribosomal protein S16
FtsK_4TM (PF13491, IPR025199): 4TM region of DNA translocase FtsK/SpoIIIE
64 MTCH1interactor110.8731.559YdjM (PF04307, IPR007404): LexA-binding, inner membrane-associated putative hydrolase
Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
65 MTMR1interactor100GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
3-PAP (PF12578, IPR022587): Myotubularin-associated protein
Myb_CC_LHEQLE (PF14379, IPR025756): MYB-CC type transfactor, LHEQLE motif
66 MYConcoprotein410.378192.989HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
67 NAA50interactor21.0000Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
68 NDC80protein found in more fusions80.6671.939DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Ndc80_HEC (PF03801, IPR005550): HEC/Ndc80p family
SlyX (PF04102, IPR007236): SlyX
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
69 NDRG1suppressor120.30320.682Ndr (PF03096, IPR004142): Ndr family
70 NEURL4interactor30.6670.250Neuralized (PF07177, IPR006573, SM00588): Neuralized
71 NFS1interactor31.0000Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V
72 NID1protein found in more fusions31.0000EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
G2F (PF07474, IPR006605, SM00682): G2F domain
NIDO (PF06119, IPR003886, SM00539): Nidogen-like
Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
73 NOS2interactor370.61757.382FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
74 NPLOC4interactor110.49114.453NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
75 NTRK1oncoprotein940.2131780.588I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
76 NXF1interactor350.242219.004NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
77 PAAF1interactor230.9640.629WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
78 PARK2suppressor570.536218.178IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
79 PCDH10suppressor21.0000Cadherin_2 (PF08266, IPR013164): Cadherin-like
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
80 PCK1interactor200.55321.046PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
81 PFKMprotein found in more fusions130.39413.508PFK (PF00365, IPR000023): Phosphofructokinase
82 PICALMoncoprotein90.5566.770ANTH (PF07651, IPR011417): ANTH domain
83 PMS2oncoprotein90.6115.072DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
MORN_2 (PF07661, IPR011652): MORN repeat variant
MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
84 POLR2Minteractor30.6670.667GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
85 POMPinteractor230.78414.960UMP1 (PF05348, IPR008012): Proteasome maturation factor UMP1
86 PPFIA1protein found in more fusions120.54517.618HWE_HK (PF07536, IPR011102, SM00911): HWE histidine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Cluap1 (PF10234, IPR019366): Clusterin-associated protein-1
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
FAM76 (PF16046, IPR032017): FAM76 protein
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
87 PPFIA2interactor60.8001.167DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
HWE_HK (PF07536, IPR011102, SM00911): HWE histidine kinase
IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SlyX (PF04102, IPR007236): SlyX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
88 PPFIA3interactor51.0000DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
T2SSF (PF00482, IPR018076): Type II secretion system (T2SS), protein F
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
Tup_N (PF08581, IPR013890): Tup N-terminal
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
FAM76 (PF16046, IPR032017): FAM76 protein
89 PPP2R5Dinteractor50.6001.951B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
90 PPWD1interactor30.6670.400DUF505 (PF04458, IPR007548): Protein of unknown function (DUF505)
Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
91 PRPF40Aprotein found in more fusions130.54510.675FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
92 PSMA1interactor600.624135.617Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
93 PSMA2interactor640.608118.454Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
94 PSMA3interactor630.595197.866Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
95 PSMA4interactor530.70662.086Proteasome (PF00227, IPR001353): Proteasome subunit
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
96 PSMA5oncoprotein620.577163.733Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
97 PSMA6interactor630.592154.996Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
98 PSMA7protein found in more fusions570.67981.365Proteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
99 PSMA8interactor310.9740.936Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
Myb_DNA-bind_5 (PF13873, IPR028002): Myb/SANT-like DNA-binding domain
100 PSMB1interactor510.73956.718Proteasome (PF00227, IPR001353): Proteasome subunit
101 PSMB2interactor490.74759.316Proteasome (PF00227, IPR001353): Proteasome subunit
102 PSMB3protein found in more fusions490.78527.283Proteasome (PF00227, IPR001353): Proteasome subunit
103 PSMB4interactor500.74043.086Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Proteasome (PF00227, IPR001353): Proteasome subunit
104 PSMB5interactor530.67983.285Proteasome (PF00227, IPR001353): Proteasome subunit
105 PSMB6interactor460.79633.422DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502)
Proteasome (PF00227, IPR001353): Proteasome subunit
106 PSMB7protein found in more fusions490.80821.823Proteasome (PF00227, IPR001353): Proteasome subunit
Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal
107 PSMB8interactor410.88211.632Proteasome (PF00227, IPR001353): Proteasome subunit
108 PSMB9interactor400.9075.843Proteasome (PF00227, IPR001353): Proteasome subunit
109 PSMC1interactor750.452462.302AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
DivIC (PF04977, IPR007060): Septum formation initiator
DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815)
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
110 PSMC3interactor740.462415.844AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
111 PSMC4interactor750.457408.276AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
NTPase_1 (PF03266, IPR004948): NTPase
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
AAA_16 (PF13191): AAA ATPase domain
112 PSMC5protein found in more fusions790.442448.759AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Laminin_II (PF06009, IPR010307): Laminin Domain II
RILP (PF11461, IPR021563): Rab interacting lysosomal protein
AAA_16 (PF13191): AAA ATPase domain
113 PSMC6interactor680.524233.315AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
114 PSMD1interactor680.536204.453PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
115 PSMD10interactor290.76622.288Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
116 PSMD11interactor620.565179.810DUF247 (PF03140, IPR004158): Plant protein of unknown function
PCI (PF01399, IPR000717, SM00088): PCI domain
AAA_16 (PF13191): AAA ATPase domain
TPR_12 (PF13424): Tetratricopeptide repeat
117 PSMD12interactor640.581141.964Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
PCI (PF01399, IPR000717, SM00088): PCI domain
118 PSMD13interactor590.617116.022Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase
PCI (PF01399, IPR000717, SM00088): PCI domain
119 PSMD14interactor640.587171.900JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
120 PSMD2oncoprotein810.410531.781PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
121 PSMD3interactor700.492274.201Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
122 PSMD4interactor650.536232.143UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
123 PSMD5interactor410.82442.163Proteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit
124 PSMD6interactor560.68268.762RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
125 PSMD7interactor600.605158.004JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
Auts2 (PF15336): Autism susceptibility gene 2 protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
126 PSMD8interactor560.67579.168CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
127 PSMD9interactor210.9431.024Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
PDZ_2 (PF13180, IPR001478): PDZ domain
128 PSME1interactor300.8409.106PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)
129 PSME2interactor290.8923.186PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
130 PSME3protein found in more fusions300.78320.361PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
131 RAB5Concoprotein80.5004.792Ras (PF00071, IPR001806, SM00173): Ras family
132 RAD21oncoprotein190.42131.070Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
133 RAD23Aoncoprotein470.711107.255UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
134 RAD23Bsuppressor290.61156.236K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
135 RELAoncoprotein150.40726.488DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
136 REToncoprotein70.6672.519Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
137 RNF185interactor150.6924.861zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
138 RNF2interactor260.27772.361zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
139 RPN1oncoprotein220.39051.106Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
140 RPS21interactor140.7694.227Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
141 RPS6KB2interactor160.42513.249Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
142 RYKoncoprotein80.32111.908Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
WIF (PF02019, IPR003306, SM00469): WIF domain
143 SCN2Binteractor21.0000DUF1191 (PF06697, IPR010605): Protein of unknown function (DUF1191)
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
144 SEC23Ainteractor130.38514.604Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
145 SEPHS1interactor50.5001.518AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain
AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
146 SHFM1protein found in more fusions430.63174.136CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
147 SHMT2interactor120.36415.832SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
148 SIRT7interactor280.31578.348DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
149 SKILsuppressor40.6671.000c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
150 SMC1Aoncoprotein150.48416.601SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
151 SMC3oncoprotein130.53813.206SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
152 SNRNP200protein found in more fusions170.45011.509DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
153 SNW1protein found in more fusions410.362176.335SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
154 SPRTNinteractor110.43611.811GreA_GreB (PF01272, IPR001437): Transcription elongation factor, GreA/GreB, C-term
SprT-like (PF10263, IPR006640, SM00731): SprT-like family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
155 SQSTM1oncoprotein250.34863.823PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
156 SUCLA2interactor60.6003.810ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain
Ligase_CoA (PF00549, IPR005811): CoA-ligase
nsp7 (PF08716, IPR014828): nsp7 replicase
157 TBPinteractor90.4647.819TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
158 TGFBR2suppressor30.6670.667ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
159 TPM4oncoprotein90.8330.808Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
160 TRAF6protein found in more fusions200.47439.300SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
161 TRIM5interactor80.6671.262Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0)
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
162 TRIOoncoprotein40.8330.100T3SS_needle_E (PF08988, IPR012671): Type III secretion system, cytoplasmic E component of needle
GRP (PF07172, IPR010800): Glycine rich protein family
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pap_E4 (PF02711, IPR003861): E4 protein
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Spectrin (PF00435, IPR002017): Spectrin repeat
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
PH_10 (PF15411): Pleckstrin homology domain
SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region
163 TSTA3interactor40.5000.729Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
NICE-3 (PF07406, IPR010876): NICE-3 protein
Polysacc_synt_2 (PF02719, IPR003869): Polysaccharide biosynthesis protein
164 TUBBinteractor260.36380.900Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
165 TXNL1interactor270.72419.403PITH (PF06201, IPR010400): PITH domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
166 UBCprotein found in more fusions770.318822.459ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
167 UBE2Concoprotein110.6224.905UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
168 UBQLN1protein found in more fusions250.48655.814Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X
169 UBQLN2protein found in more fusions190.45842.921Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
SUZ (PF12752, IPR024771): SUZ domain
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
170 UBR2interactor40.5001.750ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS
zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
171 UBR5protein found in more fusions140.34617.758CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SDA1 (PF05285, IPR007949): SDA1
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
172 UCHL5oncoprotein510.73935.722Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
173 UFC1interactor30.6670.333UFC1 (PF08694, IPR014806): Ubiquitin-fold modifier-conjugating enzyme 1
174 UFD1Linteractor110.47311.844UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
175 UNKinteractor210.21981.761MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
176 USP14interactor320.74635.509UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
177 VBP1interactor21.0000Prefoldin (PF02996, IPR004127): Prefoldin subunit
178 VPS26Aprotein found in more fusions70.5333.311Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26
179 XPO1interactor360.176305.633CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
180 YBX1oncoprotein240.30864.068CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
181 ZCCHC8interactor130.48715.591Herpes_BLRF2 (PF05812, IPR008642): Herpesvirus BLRF2 protein
PSP (PF04046, IPR006568, SM00581): PSP
zf-CCHC (PF00098, IPR001878): Zinc knuckle
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
182 ZNF512Binteractor100YTV (PF07639, IPR011521): YTV
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 COX7A2interactorCOX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
2 INSIG2interactorINSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
3 PSMC2parental proteinAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
4 PTPRFparental proteinArylsulfotrans (PF05935, IPR010262): Arylsulfotransferase (ASST)
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
DUF3377 (PF11857, IPR021805): Domain of unknown function (DUF3377)

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