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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: BP359675 is the fusion of parental proteins MAD1L1, APLP2 (from a repository: Sun Dec 18 04:25:56 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)57
The number (and %) of the onco-proteins18 (31.58 %)
The number (and %) of the tumor suppressors6 (10.53 %)
Total number of binary PPIs (saturation %)179 (11.22 %)
The number (and %) of affected PPIs56 (31.28 %)
The number of possible different fusions11
PPI diameter2
PPI radius1
The average degree of PPI5.228
Assortativity coefficient-0.3391
The network average Clustering coefficient0.548
The number (and %) of a zero Clustering coefficients12 (21.05 %)
The number (and %) of a zero Betweenness Centrality27 (47.37 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: MAD1L1,APLP2 All fusions
: BP359675;
Proteins found in more fusions AMOTL2 (see 1 fusions); TPM3 (see 2 fusions); TPM1 (see 2 fusions); TSC22D3 (see 2 fusions); UBC (see 1 fusions); NTRK1/TPR (see 1 fusions); APC (see 1 fusions); NTRK1/TPM3 (see 3 fusions); SNW1 (see 1 fusions); TRIM29 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BP359675chimera560.0602535.552MAD (PF05557, IPR008672): Mitotic checkpoint protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
2 ALOX5oncoprotein100Lipoxygenase (PF00305, IPR013819): Lipoxygenase
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
3 AMOTL2protein found in more fusions40.6671.000HOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
4 APCsuppressor50.5002.333APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
5 BAG5interactor21.0000BAG (PF02179, IPR003103, SM00264): BAG domain
PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
RRF (PF01765, IPR023584): Ribosome recycling factor
6 BAG6interactor41.0000DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
7 CCDC94interactor31.0000DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
8 CCHCR1interactor60.5005.000HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR)
9 CDC20oncoprotein110.40019.919WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
10 CDC27oncoprotein90.5368.067TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
11 CDC5Linteractor140.33341.019OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
12 CLEC11Ainteractor100ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
HBS1_N (PF08938, IPR015033): HBS1 N-terminus
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
13 COILinteractor40.6670.667CDC45 (PF02724, IPR003874): CDC45-like protein
Macoilin (PF09726, IPR019130): Transmembrane protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
14 CWF19L2interactor21.0000CwfJ_C_1 (PF04677, IPR006768): Protein similar to CwfJ C-terminus 1
CwfJ_C_2 (PF04676, IPR006767): Protein similar to CwfJ C-terminus 2
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Pap_E4 (PF02711, IPR003861): E4 protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
MRI (PF15325, IPR028278): Modulator of retrovirus infection
15 FAM131Cinteractor100FAM131 (PF15010, IPR026782): Putative cell signalling
16 FLNBoncoprotein100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
17 FOXJ2interactor21.0000SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
Spt20 (PF12090, IPR021950): Spt20 family
Pro-rich (PF15240, IPR026086): Proline-rich
18 HAUS1interactor41.0000THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
19 HDAC1suppressor80.5716.333FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
20 HDAC2suppressor110.44418.133Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
21 IKZF3suppressor60.6002.400C1_2 (PF03107, IPR004146): C1 domain
Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
22 KCNAB3interactor100Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
23 LGALSLinteractor100Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
24 MAD2L1oncoprotein90.42914.286HORMA (PF02301, IPR003511): HORMA domain
25 MAD2L1BPinteractor60.9000.286p31comet (PF06581, IPR009511): Mad1 and Cdc20-bound-Mad2 binding
26 METTL21Cinteractor21.0000Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
27 MFAP1interactor50.5004.667MFAP1 (PF06991, IPR009730): Microfibril-associated/Pre-mRNA processing
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
28 MNTsuppressor41.0000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Sipho_Gp157 (PF05565, IPR008840): Siphovirus Gp157
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
29 NEBLinteractor100Bac_small_YrzI (PF09501, IPR012655): Probable sporulation protein (Bac_small_yrzI)
Annexin (PF00191, IPR018502, SM00335): Annexin
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
SH3_9 (PF14604, IPR001452): Variant SH3 domain
30 NINLinteractor60.4677.333PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
31 NONOoncoprotein80.7622.567GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PAS_7 (PF12860): PAS fold
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
32 NRDCinteractor31.0000Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
33 NTRK1oncoprotein210.216130.086I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
34 NUDCinteractor41.0000CS (PF04969, IPR007052): CS domain
D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc.
NuDC (PF16273, IPR032572): Nuclear distribution C domain
35 PSMA1interactor60.6003.067Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
36 RNF8suppressor40.6671.000FHA (PF00498, IPR000253, SM00240): FHA domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
37 SCARA3interactor100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Filament (PF00038, IPR001664): Intermediate filament protein
Flagellin_C (PF00700, IPR001029): Bacterial flagellin C-terminal helical region
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
38 SENP3interactor50.7002.000Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
39 SIN3Aoncoprotein80.6077.733Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
40 SNW1protein found in more fusions130.40928.352SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
41 SPATA2interactor100zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
42 STK24interactor31.0000DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
43 TEX11interactor21.0000SPO22 (PF08631, IPR013940): Meiosis protein SPO22/ZIP4 like
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2547 (PF10818, IPR020508): Protein of unknown function (DUF2547)
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
AAA_28 (PF13521): AAA domain
TPR_19 (PF14559): Tetratricopeptide repeat
44 TPM1protein found in more fusions31.0000Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
45 TPM3oncoprotein50.5003.000Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
46 TPRoncoprotein40.6671.667Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
ZapB (PF06005, IPR009252): Cell division protein ZapB
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
XhlA (PF10779, IPR019715): Haemolysin XhlA
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373)
DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
47 TRIM29protein found in more fusions31.0000MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
48 TRIP13interactor80.6194.233AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
49 TSC22D3protein found in more fusions50.6671.067TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
50 TSHZ3interactor100LMP (PF04778, IPR006864): LMP repeated region
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
51 TUBGCP4interactor30.6670.500Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
52 UBCprotein found in more fusions120.23638.233ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
53 USP15oncoprotein60.7002.000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
54 VPS28interactor21.0000VPS28 (PF03997, IPR007143): VPS28 protein
55 ZSCAN32interactor200KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com
DUF3613 (PF12266, IPR022053): Protein of unknown function (DUF3613)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
56 ZW10interactor40.6671.500Zw10 (PF06248, IPR009361): Centromere/kinetochore Zw10
DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)
57 ZZEF1interactor100ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
CUB (PF00431, IPR000859, SM00042): CUB domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 APBB1interactorPID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
2 APBB2interactorPID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
3 APBB3interactorPID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
4 APLP2parental proteinAPP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
ELM2 (PF01448, IPR000949): ELM2 domain
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
Usp (PF00582, IPR006016): Universal stress protein family
YL1 (PF05764, IPR008895): YL1 nuclear protein
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
5 BRCA1suppressorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
6 DAB1interactorPID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
7 DAB2suppressorPID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
8 DEDDinteractorDED (PF01335, IPR001875, SM00031): Death effector domain
9 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
10 ETS1oncoproteinEts (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
11 HDAC5interactorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
12 HGSinteractorFYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
13 JUNoncoproteinbZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
14 JUNBoncoproteinbZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
15 KAT5suppressorMOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
16 KLK2oncoproteinTrypsin (PF00089, IPR001254, SM00020): Trypsin
17 MAD1L1parental proteinMAD (PF05557, IPR008672): Mitotic checkpoint protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
18 MAPK8oncoproteinDUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
19 RPL26oncoproteinTP2 (PF01254, IPR000678): Nuclear transition protein 2
Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
20 RYKoncoproteinPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
WIF (PF02019, IPR003306, SM00469): WIF domain
21 SFNsuppressor14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
22 VKORC1interactorVKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family
23 ZNF512BinteractorYTV (PF07639, IPR011521): YTV
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger

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